An O-fucose site in the ligand binding domain inhibits Notch activation

Development

Volumn 130, Issue 26, 2003, Pages 6411-6421

  Lei, Liang ^a   Xu, Aiguo ^a   Panin, Vladislav M ^a   Irvine, Kenneth D ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Drosophila; Fringe; Fucose; Glycosylation; Notch; O fucosyltransferase

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FUCOSYLTRANSFERASE; HYBRID PROTEIN; JAGGED1; MEMBRANE PROTEIN; MUTANT PROTEIN; N ACETYLGLUCOSAMINYLTRANSFERASE; NOTCH RECEPTOR; PROTEIN FRINGE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DROSOPHILA; EMBRYO DEVELOPMENT; EXTRACELLULAR SPACE; FORELIMB; FUCOSYLATION; GENE MUTATION; GENETIC CONSERVATION; LIGAND BINDING; MOLECULAR EVOLUTION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BODY PATTERNING; CROSSES, GENETIC; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; FUCOSE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LIGANDS; MEMBRANE PROTEINS; PROTEIN CONFORMATION; RECEPTORS, NOTCH;

EID: 0346505185     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00883     Document Type: Article

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