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Volumn 34, Issue 5, 2003, Pages 1130-1135

MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: The NILS-LSA study

Author keywords

Amine oxidoreductases; Brain infarction; Elderly; Polymorphism; White matter

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); OXIDOREDUCTASE;

EID: 0037967343     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000069163.02611.B0     Document Type: Article
Times cited : (111)

References (33)
  • 1
  • 2
    • 3543122309 scopus 로고    scopus 로고
    • Lacunar infarcts defined by magnetic resonance imaging of 3660 elderly people: The Cardiovascular Health Study
    • Longstreth WT Jr, Bernick C, Manolio TA, Bryan N, Jungreis CA, Price TR. Lacunar infarcts defined by magnetic resonance imaging of 3660 elderly people: the Cardiovascular Health Study. Arch Neurol. 1998;55: 1217-1225.
    • (1998) Arch Neurol , vol.55 , pp. 1217-1225
    • Longstreth W.T., Jr.1    Bernick, C.2    Manolio, T.A.3    Bryan, N.4    Jungreis, C.A.5    Price, T.R.6
  • 3
    • 0036144081 scopus 로고    scopus 로고
    • Prevalence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study
    • Vermeer SE, Koudstaal PJ, Oudkerk M, Hofman A, Breteler MM. Prevalence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study. Stroke. 2002;33:21-25.
    • (2002) Stroke , vol.33 , pp. 21-25
    • Vermeer, S.E.1    Koudstaal, P.J.2    Oudkerk, M.3    Hofman, A.4    Breteler, M.M.5
  • 4
    • 0030704729 scopus 로고    scopus 로고
    • Subcortical silent brain infarction as a risk factor for clinical stroke
    • Kobayashi S, Okada K, Koide H, et al. Subcortical silent brain infarction as a risk factor for clinical stroke. Stroke. 1997;28:1932-1939.
    • (1997) Stroke , vol.28 , pp. 1932-1939
    • Kobayashi, S.1    Okada, K.2    Koide, H.3
  • 5
    • 0035833961 scopus 로고    scopus 로고
    • Silent MRI infarcts and the risk of future stroke: The Cardiovascular Health Study
    • Bernick C, Kuller L, Dulberg C, Longstreth WT Jr, Manolio T, Beauchamp N, Price T, for the Cardiovascular Health Study Collaborative Research Group. Silent MRI infarcts and the risk of future stroke: the Cardiovascular Health Study. Neurology. 2001;57:1222-1229.
    • (2001) Neurology , vol.57 , pp. 1222-1229
    • Bernick, C.1    Kuller, L.2    Dulberg, C.3    Longstreth W.T., Jr.4    Manolio, T.5    Beauchamp, N.6    Price, T.7
  • 6
    • 0031910347 scopus 로고    scopus 로고
    • Relationship between ApoE, MRI findings, and cognitive function in the Cardiovascular Health Study
    • Kuller LH, Shemanski L, Manolio T, et al. Relationship between ApoE, MRI findings, and cognitive function in the Cardiovascular Health Study. Stroke. 1998;29:388-398.
    • (1998) Stroke , vol.29 , pp. 388-398
    • Kuller, L.H.1    Shemanski, L.2    Manolio, T.3
  • 7
    • 0031970953 scopus 로고    scopus 로고
    • Cigarette smoking and other risk factors for silent cerebral infarction in the general population
    • Howard G, Wagenknecht LE, Cai J, Cooper L, Kraut MA, Toole JF. Cigarette smoking and other risk factors for silent cerebral infarction in the general population. Stroke. 1998;29:913-917.
    • (1998) Stroke , vol.29 , pp. 913-917
    • Howard, G.1    Wagenknecht, L.E.2    Cai, J.3    Cooper, L.4    Kraut, M.A.5    Toole, J.F.6
  • 9
    • 0032829537 scopus 로고    scopus 로고
    • Evaluation of genetic risk factors for silent brain infarction
    • Notsu Y, Nabika T, Park H-Y, Masuda J, Kobayashi S. Evaluation of genetic risk factors for silent brain infarction. Stroke. 1999;30: 1881-1886.
    • (1999) Stroke , vol.30 , pp. 1881-1886
    • Notsu, Y.1    Nabika, T.2    Park, H.-Y.3    Masuda, J.4    Kobayashi, S.5
  • 13
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: Probable benefits of increasing folic acid intakes
    • Boushey CJ, Beresford SA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of increasing folic acid intakes. JAMA. 1995;274: 1049-1057.
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 14
    • 0032497941 scopus 로고    scopus 로고
    • Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: The result of a meta-analysis
    • Brattstrom L, Wilcken DE, Ohrvik J, Brudin L. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. Circulation. 1998;98:2520-2526.
    • (1998) Circulation , vol.98 , pp. 2520-2526
    • Brattstrom, L.1    Wilcken, D.E.2    Ohrvik, J.3    Brudin, L.4
  • 15
    • 34248517136 scopus 로고    scopus 로고
    • A new comprehensive study on aging: The National Institute for Longevity Sciences, Longitudinal Study of Aging (NILS-LSA)
    • Shimokata H, Ando F, Niino N. A new comprehensive study on aging: the National Institute for Longevity Sciences, Longitudinal Study of Aging (NILS-LSA). J Epidemiol. 2000;10(suppl):S1-S9.
    • (2000) J Epidemiol , vol.10 , Issue.SUPPL.
    • Shimokata, H.1    Ando, F.2    Niino, N.3
  • 16
    • 0030715595 scopus 로고    scopus 로고
    • Postural dysregulation in systolic blood pressure is associated with worsened scoring on neurobehavioral function tests and leukoariosis in the older elderly living in a community
    • Matsubayashi K, Okumiya K, Wada T, Osaki Y, Fujisawa M, Doi Y, Ozawa T. Postural dysregulation in systolic blood pressure is associated with worsened scoring on neurobehavioral function tests and leukoariosis in the older elderly living in a community. Stroke. 1997;28:2169-2173.
    • (1997) Stroke , vol.28 , pp. 2169-2173
    • Matsubayashi, K.1    Okumiya, K.2    Wada, T.3    Osaki, Y.4    Fujisawa, M.5    Doi, Y.6    Ozawa, T.7
  • 17
    • 0032924043 scopus 로고    scopus 로고
    • Postprandial hypotension is associated with asymptomatic cerebrovascular damage in essential hypertensive patients
    • Kohara K, Jiang YN, Igase M, Takata Y, Fukuoka T, Okura T, Kitami Y, Hiwada K. Postprandial hypotension is associated with asymptomatic cerebrovascular damage in essential hypertensive patients. Hypertension. 1999;33:565-568.
    • (1999) Hypertension , vol.33 , pp. 565-568
    • Kohara, K.1    Jiang, Y.N.2    Igase, M.3    Takata, Y.4    Fukuoka, T.5    Okura, T.6    Kitami, Y.7    Hiwada, K.8
  • 21
    • 0035864690 scopus 로고    scopus 로고
    • The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British Regional Heart Study
    • Dekou V, Whincup P, Papacosta O, Ebrahim S, Lennon L, Ueland PM, Refsum H, Humphries SE, Gudnason V. The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British Regional Heart Study. Atherosclerosis. 2001;154:659-666.
    • (2001) Atherosclerosis , vol.154 , pp. 659-666
    • Dekou, V.1    Whincup, P.2    Papacosta, O.3    Ebrahim, S.4    Lennon, L.5    Ueland, P.M.6    Refsum, H.7    Humphries, S.E.8    Gudnason, V.9
  • 22
    • 0030914882 scopus 로고    scopus 로고
    • Silent brain infarction on magnetic resonance imaging and neurological abnormalities in community-dwelling older adults: The Cardiovascular Health Study (CHS) Collaborative Research Group
    • Price TR, Manolio TA, Kronmal RA, Kittner SJ, Yue NC, Robbins J, Anton-Culver H, O'Leary DH. Silent brain infarction on magnetic resonance imaging and neurological abnormalities in community-dwelling older adults: the Cardiovascular Health Study (CHS) Collaborative Research Group. Stroke. 1997;28:1158-1164.
    • (1997) Stroke , vol.28 , pp. 1158-1164
    • Price, T.R.1    Manolio, T.A.2    Kronmal, R.A.3    Kittner, S.J.4    Yue, N.C.5    Robbins, J.6    Anton-Culver, H.7    O'Leary, D.H.8
  • 23
    • 0033231246 scopus 로고    scopus 로고
    • Neuroanatomic and functional correlates of depressed mood: The Cardiovascular Health Study
    • Sato R, Bryan RN, Fried LP. Neuroanatomic and functional correlates of depressed mood: the Cardiovascular Health Study. Am J Epidemiol. 1999;150:919-929.
    • (1999) Am J Epidemiol , vol.150 , pp. 919-929
    • Sato, R.1    Bryan, R.N.2    Fried, L.P.3
  • 24
    • 0033081010 scopus 로고    scopus 로고
    • Relation of left ventricular hypertrophy and geometry to asymptomatic cerebrovascular damage in essential hypertension
    • Kohara K, Zhao B, Jiang YN, Takata Y, Fukuoka T, Igase M, Miki T, Hiwada K. Relation of left ventricular hypertrophy and geometry to asymptomatic cerebrovascular damage in essential hypertension. Am J Cardiol. 1999;83:367-370.
    • (1999) Am J Cardiol , vol.83 , pp. 367-370
    • Kohara, K.1    Zhao, B.2    Jiang, Y.N.3    Takata, Y.4    Fukuoka, T.5    Igase, M.6    Miki, T.7    Hiwada, K.8
  • 26
    • 0033888475 scopus 로고    scopus 로고
    • Pathogenicity of thermolabile methylenetetrahydrofolate reductase for vascular dementia
    • Yoo J-H, Choi G-D, Kang S-S. Pathogenicity of thermolabile methylenetetrahydrofolate reductase for vascular dementia. Arterioscler Thromb Vasc Biol. 2000;20:1921-1925.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1921-1925
    • Yoo, J.-H.1    Choi, G.-D.2    Kang, S.-S.3
  • 27
    • 37849186628 scopus 로고    scopus 로고
    • Apolipoprotein E. methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia: An epidemiological study using the polymerase chain reaction (PCR) method
    • Nishiyama M, Kato Y, Hashimoto M, Yukawa S, Omori K. Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia: an epidemiological study using the polymerase chain reaction (PCR) method. J Epidemiol. 2000;10: 163-172.
    • (2000) J Epidemiol , vol.10 , pp. 163-172
    • Nishiyama, M.1    Kato, Y.2    Hashimoto, M.3    Yukawa, S.4    Omori, K.5
  • 30
    • 0033855267 scopus 로고    scopus 로고
    • Oxidative stress in the context of acute cerebrovascular stroke
    • El Kossi MM, Zakhary MM. Oxidative stress in the context of acute cerebrovascular stroke. Stroke. 2000;31:1889-1892.
    • (2000) Stroke , vol.31 , pp. 1889-1892
    • El Kossi, M.M.1    Zakhary, M.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.