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Volumn 28, Issue 1, 2003, Pages 15-27

p53-dependent cell death signaling in neurons

Author keywords

Apoptosis; Bcl 2 family; Caspase; Cell death; Neurons neurodegeneration; p53

Indexed keywords

CASPASE; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

EID: 0037263789     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021687810103     Document Type: Article
Times cited : (171)

References (143)
  • 1
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko, L. J. and Prives, C. 1996. p53: Puzzle and paradigm. Genes Dev. 10:1054-1072.
    • (1996) Genes Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 2
    • 0032192140 scopus 로고    scopus 로고
    • The complexity of p53 modulation: Emerging patterns from divergent signals
    • Giaccia, A. J. and Kastan, M. B. 1998. The complexity of p53 modulation: Emerging patterns from divergent signals. Genes Dev. 12:2973-2983.
    • (1998) Genes Dev. , vol.12 , pp. 2973-2983
    • Giaccia, A.J.1    Kastan, M.B.2
  • 3
    • 0029670589 scopus 로고    scopus 로고
    • p53 in signaling checkpoint arrest or apoptosis
    • Bates, S. and Vousden, K. H. 1996. p53 in signaling checkpoint arrest or apoptosis. Curr. Opin. Genet. Dev. 6:12-18.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 12-18
    • Bates, S.1    Vousden, K.H.2
  • 5
    • 0028292480 scopus 로고
    • Identification of a p53-dependent negative response element in the bcl- 2 gene
    • Miyashita, T., Harigai, M., Hanada, M., and Reed, J. C. 1994. Identification of a p53-dependent negative response element in the bcl- 2 gene. Cancer Res. 54:3131-3135.
    • (1994) Cancer Res. , vol.54 , pp. 3131-3135
    • Miyashita, T.1    Harigai, M.2    Hanada, M.3    Reed, J.C.4
  • 7
    • 0032561471 scopus 로고    scopus 로고
    • Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system
    • Ding, H. F., McGill, G., Rowan, S., Schmaltz, C., Shimamura, A., and Fisher, D. E. 1998. Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system. J. Biol. Chem. 273:28378-28383.
    • (1998) J. Biol. Chem. , vol.273 , pp. 28378-28383
    • Ding, H.F.1    McGill, G.2    Rowan, S.3    Schmaltz, C.4    Shimamura, A.5    Fisher, D.E.6
  • 8
    • 0032127463 scopus 로고    scopus 로고
    • p53 facilitates pRb cleavage in IL-3 deprived cells: Novel pro-apoptotic activity of p53
    • Gottlieb, E. and Oren, M. 1998. p53 facilitates pRb cleavage in IL-3 deprived cells: Novel pro-apoptotic activity of p53. EMBO J. 17:3587-3596.
    • (1998) EMBO J. , vol.17 , pp. 3587-3596
    • Gottlieb, E.1    Oren, M.2
  • 10
    • 0029867466 scopus 로고    scopus 로고
    • Nuclear accumulation of p53 protein following kainic acid-induced seizures
    • Sakhi, S., Sun, N., Wing, L. L., Mehta, P., and Schreiber, S. S. 1996. Nuclear accumulation of p53 protein following kainic acid-induced seizures. Neuroreport. 7:493-496.
    • (1996) Neuroreport , vol.7 , pp. 493-496
    • Sakhi, S.1    Sun, N.2    Wing, L.L.3    Mehta, P.4    Schreiber, S.S.5
  • 11
    • 0037154781 scopus 로고    scopus 로고
    • Differential induction of p53 in immature and adult rat brain following lithium-pilocarpine status epilepticus
    • Tan, Z., Sankar, R., Shin, D., Sun, N., Liu, H., Wasterlain, C. G., and Schreiber, S. S. 2002. Differential induction of p53 in immature and adult rat brain following lithium-pilocarpine status epilepticus. Brain Res. 928:187-193.
    • (2002) Brain Res. , vol.928 , pp. 187-193
    • Tan, Z.1    Sankar, R.2    Shin, D.3    Sun, N.4    Liu, H.5    Wasterlain, C.G.6    Schreiber, S.S.7
  • 12
    • 0033561799 scopus 로고    scopus 로고
    • Nuclear factor kappaB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum
    • Qin, Z. H., Chen, R. W., Wang, Y., Nakai, M., Chuang, D. M., and Chase, T. N. 1999. Nuclear factor kappaB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum. J. Neurosci. 19:4023-4033.
    • (1999) J. Neurosci. , vol.19 , pp. 4023-4033
    • Qin, Z.H.1    Chen, R.W.2    Wang, Y.3    Nakai, M.4    Chuang, D.M.5    Chase, T.N.6
  • 13
    • 0032753026 scopus 로고    scopus 로고
    • Co-stimulation of cyclic-AMP-linked metabotropic glutamate receptors in rat striatum attenuates excitotoxin-induced nuclear factor-kappaB activation and apoptosis
    • Wang, Y., Qin, Z. H., Nakai, M., Chen, R. W., Chuang, D. M., and Chase, T. N. 1999. Co-stimulation of cyclic-AMP-linked metabotropic glutamate receptors in rat striatum attenuates excitotoxin-induced nuclear factor-kappaB activation and apoptosis. Neuroscience. 94:1153-1162.
    • (1999) Neuroscience , vol.94 , pp. 1153-1162
    • Wang, Y.1    Qin, Z.H.2    Nakai, M.3    Chen, R.W.4    Chuang, D.M.5    Chase, T.N.6
  • 14
    • 0033966324 scopus 로고    scopus 로고
    • Kainic acid-induced apoptosis in rat striatum is associated with nuclear factor-kappaB activation
    • Nakai, M., Qin, Z. H., Chen, J. F., Wang, Y., and Chase, T. N. 2000. Kainic acid-induced apoptosis in rat striatum is associated with nuclear factor-kappaB activation. J. Neurochem. 74:647-658.
    • (2000) J. Neurochem. , vol.74 , pp. 647-658
    • Nakai, M.1    Qin, Z.H.2    Chen, J.F.3    Wang, Y.4    Chase, T.N.5
  • 15
    • 0033059025 scopus 로고    scopus 로고
    • The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury
    • Napieralski, J. A., Raghupathi, R., and McIntosh, T. K. 1999. The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury. Brain Res. Mol. Brain Res. 71:78-86.
    • (1999) Brain Res. Mol. Brain Res. , vol.71 , pp. 78-86
    • Napieralski, J.A.1    Raghupathi, R.2    McIntosh, T.K.3
  • 16
    • 0032847633 scopus 로고    scopus 로고
    • Postinjury magnesium treatment attenuates traumatic brain injury-induced cortical induction of p53 mRNA in rats
    • Muir, J. K., Raghupathi, R., Emery, D. L., Bareyre, F. M., and McIntosh, T. K. 1999. Postinjury magnesium treatment attenuates traumatic brain injury-induced cortical induction of p53 mRNA in rats. Exp. Neurol. 159:584-593.
    • (1999) Exp. Neurol. , vol.159 , pp. 584-593
    • Muir, J.K.1    Raghupathi, R.2    Emery, D.L.3    Bareyre, F.M.4    McIntosh, T.K.5
  • 17
    • 0026607994 scopus 로고
    • p53 expression in brain after middle cerebral artery occlusion in the rat
    • Chopp, M., Li, Y., Zhang, Z. G., and Freytag, S. O. 1992. p53 expression in brain after middle cerebral artery occlusion in the rat. Biochem Biophys Res Commun. 182:1201-1207.
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 1201-1207
    • Chopp, M.1    Li, Y.2    Zhang, Z.G.3    Freytag, S.O.4
  • 18
    • 0033533086 scopus 로고    scopus 로고
    • Increase in p53 protein expression following cortical infarction in the spontaneously hypertensive rat
    • Watanabe, H., Ohta, S., Kumon, Y., Sakaki, S., and Sakanaka, M. 1999. Increase in p53 protein expression following cortical infarction in the spontaneously hypertensive rat. Brain Res. 837:38-45.
    • (1999) Brain Res. , vol.837 , pp. 38-45
    • Watanabe, H.1    Ohta, S.2    Kumon, Y.3    Sakaki, S.4    Sakanaka, M.5
  • 21
    • 0027407570 scopus 로고
    • Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells
    • Busciglio, J., Gabuzda, D. H., Matsudaira, P., and Yankner, B. A. 1993. Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells. Proc. Natl. Acad. Sci. U.S.A. 90:2092-2096.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 2092-2096
    • Busciglio, J.1    Gabuzda, D.H.2    Matsudaira, P.3    Yankner, B.A.4
  • 22
    • 0030831489 scopus 로고    scopus 로고
    • Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease
    • de la Monte, S. M., Sohn, Y. K., and Wands, J. R. 1997. Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease. J. Neurol. Sci. 152:73-83.
    • (1997) J. Neurol. Sci. , vol.152 , pp. 73-83
    • De la Monte, S.M.1    Sohn, Y.K.2    Wands, J.R.3
  • 23
    • 0031959496 scopus 로고    scopus 로고
    • P53- and CD95-associated apoptosis in neurodegenerative diseases
    • de la Monte, S. M., Sohn, Y. K., Ganju, N., and Wands, J. R. 1998. P53- and CD95-associated apoptosis in neurodegenerative diseases. Lab. Invest. 78:401-411.
    • (1998) Lab. Invest. , vol.78 , pp. 401-411
    • De la Monte, S.M.1    Sohn, Y.K.2    Ganju, N.3    Wands, J.R.4
  • 24
    • 0029823454 scopus 로고    scopus 로고
    • Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice
    • LaFerla, F. M., Hall, C. K., Ngo, L., and Jay, G. 1996. Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice. J. Clin. Invest. 98:1626-1632.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1626-1632
    • LaFerla, F.M.1    Hall, C.K.2    Ngo, L.3    Jay, G.4
  • 25
    • 0032192481 scopus 로고    scopus 로고
    • Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation
    • Jiang, Y. H., Armstrong, D., Albrecht, U., Atkins, C. M., Noebels, J. L., Eichele, G., Sweatt, J. D., and Beaudet, A. L. 1998. Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. Neuron. 21:799-811.
    • (1998) Neuron , vol.21 , pp. 799-811
    • Jiang, Y.H.1    Armstrong, D.2    Albrecht, U.3    Atkins, C.M.4    Noebels, J.L.5    Eichele, G.6    Sweatt, J.D.7    Beaudet, A.L.8
  • 26
    • 0032585811 scopus 로고    scopus 로고
    • Neuronal cell death in Down's syndrome
    • Sawa, A. 1999. Neuronal cell death in Down's syndrome. J. Neural Transm. Suppl. 57:87-97.
    • (1999) J. Neural Transm. Suppl. , vol.57 , pp. 87-97
    • Sawa, A.1
  • 27
    • 0033593483 scopus 로고    scopus 로고
    • Apoptosis-associated proteins p53 and APO-1/Fas (CD95) in brains of adult patients with Down syndrome
    • Seidl, R., Fang-Kircher, S., Bidmon, B., Cairns, N., and Lubec, G. 1999. Apoptosis-associated proteins p53 and APO-1/Fas (CD95) in brains of adult patients with Down syndrome. Neurosci. Lett. 260:9-12.
    • (1999) Neurosci. Lett. , vol.260 , pp. 9-12
    • Seidl, R.1    Fang-Kircher, S.2    Bidmon, B.3    Cairns, N.4    Lubec, G.5
  • 28
    • 0034517935 scopus 로고    scopus 로고
    • p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis
    • Martin, L. J. 2000. p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis. Neurobiol. Dis. 7:613-622.
    • (2000) Neurobiol. Dis. , vol.7 , pp. 613-622
    • Martin, L.J.1
  • 30
    • 0031842231 scopus 로고    scopus 로고
    • Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids
    • Uberti, D., Belloni, M., Grilli, M., Spano, P., and Memo, M. 1998. Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids. Eur. J. Neurosci. 10:246-254.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 246-254
    • Uberti, D.1    Belloni, M.2    Grilli, M.3    Spano, P.4    Memo, M.5
  • 31
    • 0033525538 scopus 로고    scopus 로고
    • Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression: A prominent role in neuroprotection against excitotoxicity
    • Chen, R. W. and Chuang, D. M. 1999. Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression: A prominent role in neuroprotection against excitotoxicity. J. Biol. Chem. 274:6039-6042.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6039-6042
    • Chen, R.W.1    Chuang, D.M.2
  • 32
    • 0033556356 scopus 로고    scopus 로고
    • A role for MAPK/ERK in sympathetic neuron survival: Protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside
    • Anderson, C. N. G. and Tolkovsky, A. M. 1999. A role for MAPK/ERK in sympathetic neuron survival: Protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside. J. Neurosci. 19:664-673.
    • (1999) J. Neurosci. , vol.19 , pp. 664-673
    • Anderson, C.N.G.1    Tolkovsky, A.M.2
  • 33
    • 0033232529 scopus 로고    scopus 로고
    • Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: Evidence that GAPDH is upregulated by p53
    • Chen, R. W., Saunders, P. A., Wei, H., Li, Z., Seth, P., and Chuang, D. M. 1999. Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: Evidence that GAPDH is upregulated by p53. J. Neurosci. 19:9654-9662.
    • (1999) J. Neurosci. , vol.19 , pp. 9654-9662
    • Chen, R.W.1    Saunders, P.A.2    Wei, H.3    Li, Z.4    Seth, P.5    Chuang, D.M.6
  • 35
    • 0035879071 scopus 로고    scopus 로고
    • Cyclin-dependent kinases and p53 pathways are activated independently and mediate Bax activation in neurons after DNA damage
    • Morris, E. J., Keramaris, E., Rideout, H. J., Slack, R. S., Dyson, N. J., Stefanis, L., and Park, D. S. 2001. Cyclin-dependent kinases and p53 pathways are activated independently and mediate Bax activation in neurons after DNA damage. J. Neurosci. 21:5017-5026.
    • (2001) J. Neurosci. , vol.21 , pp. 5017-5026
    • Morris, E.J.1    Keramaris, E.2    Rideout, H.J.3    Slack, R.S.4    Dyson, N.J.5    Stefanis, L.6    Park, D.S.7
  • 37
    • 0032578028 scopus 로고    scopus 로고
    • Hypoxia-induced apoptosis: Effect of hypoxic severity and role of p53 in neuronal cell death
    • Banasiak, K. J. and Haddad, G. G. 1998. Hypoxia-induced apoptosis: Effect of hypoxic severity and role of p53 in neuronal cell death. Brain Res. 797:295-304.
    • (1998) Brain Res. , vol.797 , pp. 295-304
    • Banasiak, K.J.1    Haddad, G.G.2
  • 38
    • 0032517786 scopus 로고    scopus 로고
    • p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors
    • Aloyz, R. S., Bamji, S. X., Pozniak, C. D., Toma, J. G., Atwal, J., Kaplan, D. R., and Miller, F. D. 1998. p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors. J. Cell Biol. 143:1691-1703.
    • (1998) J. Cell Biol. , vol.143 , pp. 1691-1703
    • Aloyz, R.S.1    Bamji, S.X.2    Pozniak, C.D.3    Toma, J.G.4    Atwal, J.5    Kaplan, D.R.6    Miller, F.D.7
  • 39
    • 0027985453 scopus 로고
    • Attenuation of p53 expression protects against focal ischemic damage in transgenic mice
    • Crumrine, R. C., Thomas, A. L., and Morgan, P. F. 1994. Attenuation of p53 expression protects against focal ischemic damage in transgenic mice. J. Cereb. Blood Flow Metab. 14:887-891.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 887-891
    • Crumrine, R.C.1    Thomas, A.L.2    Morgan, P.F.3
  • 40
    • 0032534625 scopus 로고    scopus 로고
    • Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons
    • Johnson, M. D., Xiang, H., London, S., Kinoshita, Y., Knudson, M., Mayberg, M., Korsmeyer, S. J., and Morrison, R. S. 1998. Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons. J. Neurosci. Res. 54:721-733.
    • (1998) J. Neurosci. Res. , vol.54 , pp. 721-733
    • Johnson, M.D.1    Xiang, H.2    London, S.3    Kinoshita, Y.4    Knudson, M.5    Mayberg, M.6    Korsmeyer, S.J.7    Morrison, R.S.8
  • 41
    • 0029086989 scopus 로고
    • The role of free radicals and p53 in neuron apoptosis in vivo
    • Wood, K. A. and Youle, R. J. 1995. The role of free radicals and p53 in neuron apoptosis in vivo. J. Neurosci. 15:5851-5857.
    • (1995) J. Neurosci. , vol.15 , pp. 5851-5857
    • Wood, K.A.1    Youle, R.J.2
  • 42
    • 0029745387 scopus 로고    scopus 로고
    • Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons
    • Enokido, Y., Araki, T., Tanaka, K., Aizawa, S., and Hatanaka, H. 1996. Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons. Eur. J. Neurosci. 8: 1812-1821.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1812-1821
    • Enokido, Y.1    Araki, T.2    Tanaka, K.3    Aizawa, S.4    Hatanaka, H.5
  • 43
    • 0032524070 scopus 로고    scopus 로고
    • Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
    • Herzog, K. H., Chong, M. J., Kapsetaki, M., Morgan, J. I., and McKinnon, P. J. 1998. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science. 280:1089-1091.
    • (1998) Science , vol.280 , pp. 1089-1091
    • Herzog, K.H.1    Chong, M.J.2    Kapsetaki, M.3    Morgan, J.I.4    McKinnon, P.J.5
  • 44
    • 0035138404 scopus 로고    scopus 로고
    • DNA damage-induced neural precursor cell apoptosis requires p53 and caspase 9 but neither Bax nor caspase 3
    • D'Sa-Eipper, C., Leonard, J. R., Putcha, G., Zheng, T. S., Flavell, R. A., Rakic, P., Kuida, K., and Roth, K. A. 2001. DNA damage-induced neural precursor cell apoptosis requires p53 and caspase 9 but neither Bax nor caspase 3. Development. 128:137-146.
    • (2001) Development , vol.128 , pp. 137-146
    • D'Sa-Eipper, C.1    Leonard, J.R.2    Putcha, G.3    Zheng, T.S.4    Flavell, R.A.5    Rakic, P.6    Kuida, K.7    Roth, K.A.8
  • 46
    • 0030249597 scopus 로고    scopus 로고
    • Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity
    • Trimmer, P. A., Smith, T. S., Jung, A. B., and Bennett, J. P., Jr. 1996. Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity. Neurodegeneration. 5:233-239.
    • (1996) Neurodegeneration , vol.5 , pp. 233-239
    • Trimmer, P.A.1    Smith, T.S.2    Jung, A.B.3    Bennett J.P., Jr.4
  • 47
    • 0030840777 scopus 로고    scopus 로고
    • p53-knockout mice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies
    • Hirata, H. and Cadet, J. L. 1997. p53-knockout mice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies. J. Neurochem. 69:780-790.
    • (1997) J. Neurochem. , vol.69 , pp. 780-790
    • Hirata, H.1    Cadet, J.L.2
  • 48
    • 0030945412 scopus 로고    scopus 로고
    • p53-deficient mice are protected against adrenalectomyinduced apoptosis
    • Sakhi, S., Gilmore, W., Tran, N. D., and Schreiber, S. S. 1996. p53-deficient mice are protected against adrenalectomyinduced apoptosis. Neuroreport. 8:233-235.
    • (1996) Neuroreport , vol.8 , pp. 233-235
    • Sakhi, S.1    Gilmore, W.2    Tran, N.D.3    Schreiber, S.S.4
  • 49
    • 0035821429 scopus 로고    scopus 로고
    • Injury-induced apoptosis of neurons in adult brain is mediated by p53-dependent and p53-independent pathways and requires Bax
    • Martin, L. J., Kaiser, A., Yu, J. W., Natale, J. E., and Al-Abdulla, N. A. 2001. Injury-induced apoptosis of neurons in adult brain is mediated by p53-dependent and p53-independent pathways and requires Bax. J. Comp. Neurol. 433:299-311.
    • (2001) J. Comp. Neurol. , vol.433 , pp. 299-311
    • Martin, L.J.1    Kaiser, A.2    Yu, J.W.3    Natale, J.E.4    Al-Abdulla, N.A.5
  • 50
    • 0030031650 scopus 로고    scopus 로고
    • p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons
    • Enokido, Y., Araki, T., Aizawa, S., and Hatanaka, H. 1996. p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons. Neurosci. Lett. 203:1-4.
    • (1996) Neurosci. Lett. , vol.203 , pp. 1-4
    • Enokido, Y.1    Araki, T.2    Aizawa, S.3    Hatanaka, H.4
  • 51
    • 0032104138 scopus 로고    scopus 로고
    • Changes in c-Jun but not Bcl-2 family proteins in p53-dependent apoptosis of mouse cerebellar granule neurons induced by DNA damaging agent bleomycin
    • Araki, T., Enokido, Y., Inamura, N., Aizawa, S., Reed, J. C., and Hatanaka, H. 1998. Changes in c-Jun but not Bcl-2 family proteins in p53-dependent apoptosis of mouse cerebellar granule neurons induced by DNA damaging agent bleomycin. Brain Res. 794:239-247.
    • (1998) Brain Res. , vol.794 , pp. 239-247
    • Araki, T.1    Enokido, Y.2    Inamura, N.3    Aizawa, S.4    Reed, J.C.5    Hatanaka, H.6
  • 54
    • 0033566792 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 alpha mediates hypoxia-induced delayed neuronal death that involves p53
    • Halterman, M. W., Miller, C. C., and Federoff, H. J. 1999. Hypoxia-inducible factor-1 alpha mediates hypoxia-induced delayed neuronal death that involves p53. J. Neurosci. 19:6818-6824.
    • (1999) J. Neurosci. , vol.19 , pp. 6818-6824
    • Halterman, M.W.1    Miller, C.C.2    Federoff, H.J.3
  • 55
    • 0031860507 scopus 로고    scopus 로고
    • Sympathetic neuron survival and proliferation are prolonged by loss of p53 and neurofibromin
    • Vogel, K. S. and Parada. L. F. 1998. Sympathetic neuron survival and proliferation are prolonged by loss of p53 and neurofibromin. Mol. Cell Neurosci. 11:19-28.
    • (1998) Mol. Cell Neurosci. , vol.11 , pp. 19-28
    • Vogel, K.S.1    Parada, L.F.2
  • 56
    • 0026744563 scopus 로고
    • Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
    • Lee, E. Y., Chang, C. Y., Hu, N., Wang, Y. C., Lai, C. C., Herrup, K., Lee, W. H., and Bradley, A. 1992. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature. 359:288-294.
    • (1992) Nature , vol.359 , pp. 288-294
    • Lee, E.Y.1    Chang, C.Y.2    Hu, N.3    Wang, Y.C.4    Lai, C.C.5    Herrup, K.6    Lee, W.H.7    Bradley, A.8
  • 57
    • 0029910628 scopus 로고    scopus 로고
    • Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
    • Macleod, K. F., Hu, Y., and Jacks, T. 1996. Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO. J. 15:6178-6188.
    • (1996) EMBO. J. , vol.15 , pp. 6178-6188
    • Macleod, K.F.1    Hu, Y.2    Jacks, T.3
  • 58
    • 0032485244 scopus 로고    scopus 로고
    • Inhibition of HIV-1 gp120-induced apoptosis in neuroblastoma SKN-SH cells by an antisense oligodeoxynucleotide against p53
    • Yeung, M. C., Geertsma, F., Liu, J., and Lau, A. S. 1998. Inhibition of HIV-1 gp120-induced apoptosis in neuroblastoma SKN-SH cells by an antisense oligodeoxynucleotide against p53. AIDS 12:349-354.
    • (1998) AIDS , vol.12 , pp. 349-354
    • Yeung, M.C.1    Geertsma, F.2    Liu, J.3    Lau, A.S.4
  • 59
    • 0035943738 scopus 로고    scopus 로고
    • Neurons are protected from excitotoxic death by p53 antisense oligonucleotides delivered in anionic liposomes
    • Lakkaraju, A., Dubinsky, J. M., Low, W. C., and Rahman, Y. E. 2001. Neurons are protected from excitotoxic death by p53 antisense oligonucleotides delivered in anionic liposomes. J. Biol. Chem. 276:32000-32007.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32000-32007
    • Lakkaraju, A.1    Dubinsky, J.M.2    Low, W.C.3    Rahman, Y.E.4
  • 60
    • 0035085210 scopus 로고    scopus 로고
    • A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide
    • Culmsee, C., Zhu, X., Yu, Q. S., Chan, S. L., Camandola, S., Guo, Z., Greig, N. H., and Mattson, M. P. 2001. A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide. J Neurochem. 77:220-228.
    • (2001) J. Neurochem. , vol.77 , pp. 220-228
    • Culmsee, C.1    Zhu, X.2    Yu, Q.S.3    Chan, S.L.4    Camandola, S.5    Guo, Z.6    Greig, N.H.7    Mattson, M.P.8
  • 61
    • 0037017399 scopus 로고    scopus 로고
    • Selective cytotoxicity of intracellular amyloid {beta} peptide 1-42 through p53 and Bax in cultured primary human neurons
    • Zhang, Y., McLaughlin, R., Goodyer, C., and LeBlanc, A. 2002. Selective cytotoxicity of intracellular amyloid {beta} peptide 1-42 through p53 and Bax in cultured primary human neurons. J. Cell Biol. 156:519-529.
    • (2002) J. Cell Biol. , vol.156 , pp. 519-529
    • Zhang, Y.1    McLaughlin, R.2    Goodyer, C.3    LeBlanc, A.4
  • 62
    • 0035664111 scopus 로고    scopus 로고
    • Reduction of purkinje cell pathology in SCA1 transgenic mice by p53 deletion
    • Shahbazian, M. D., Orr, H. T., and Zoghbi, H. Y. 2001. Reduction of purkinje cell pathology in SCA1 transgenic mice by p53 deletion. Neurobiol. Dis. 8:974-981.
    • (2001) Neurobiol. Dis. , vol.8 , pp. 974-981
    • Shahbazian, M.D.1    Orr, H.T.2    Zoghbi, H.Y.3
  • 63
    • 0033560927 scopus 로고    scopus 로고
    • Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation
    • Johnson, M. D., Kinoshita, Y., Xiang, H., Ghatan, S., and Morrison, R. S. 1999. Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation. J. Neurosci. 19:2996-3006.
    • (1999) J. Neurosci. , vol.19 , pp. 2996-3006
    • Johnson, M.D.1    Kinoshita, Y.2    Xiang, H.3    Ghatan, S.4    Morrison, R.S.5
  • 65
    • 0035232146 scopus 로고    scopus 로고
    • Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease
    • Mattson, M. P., Gary, D. S., Chan, S. L., and Duan, W. 2001. Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease. Biochem. Soc. Symp. 67:151-162.
    • (2001) Biochem. Soc. Symp. , vol.67 , pp. 151-162
    • Mattson, M.P.1    Gary, D.S.2    Chan, S.L.3    Duan, W.4
  • 66
    • 0033834503 scopus 로고    scopus 로고
    • Absence of p53: No effect in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Kuntz, C. T., Kinoshita, Y., Beal, M. F., Donehower, L. A., and Morrison, R. S. 2000. Absence of p53: No effect in a transgenic mouse model of familial amyotrophic lateral sclerosis. Exp. Neurol. 165:184-190.
    • (2000) Exp. Neurol. , vol.165 , pp. 184-190
    • Kuntz, C.T.1    Kinoshita, Y.2    Beal, M.F.3    Donehower, L.A.4    Morrison, R.S.5
  • 67
    • 0034613225 scopus 로고    scopus 로고
    • Motor neuron cell death in a mouse model of FALS is not mediated by the p53 cell survival regulator
    • Prudlo, J., Koenig, J., Graser, J., Burckhardt, E., Mestres, P., Menger, M., and Roemer, K. 2000. Motor neuron cell death in a mouse model of FALS is not mediated by the p53 cell survival regulator. Brain Res. 879:183-187.
    • (2000) Brain Res. , vol.879 , pp. 183-187
    • Prudlo, J.1    Koenig, J.2    Graser, J.3    Burckhardt, E.4    Mestres, P.5    Menger, M.6    Roemer, K.7
  • 68
    • 0029055808 scopus 로고
    • Activation of p53 sequencespecific DNA binding by short single strands of DNA requires the p53 C-terminus
    • Jayaraman, J. and Prives, C. 1995. Activation of p53 sequencespecific DNA binding by short single strands of DNA requires the p53 C-terminus. Cell. 81:1021-1029.
    • (1995) Cell , vol.81 , pp. 1021-1029
    • Jayaraman, J.1    Prives, C.2
  • 69
    • 0029897210 scopus 로고    scopus 로고
    • Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest
    • Huang, L. C., Clarkin, K. C., and Wahl, G. M. 1996. Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest. Proc. Natl. Acad. Sci. U.S.A. 93:4827-4832.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 4827-4832
    • Huang, L.C.1    Clarkin, K.C.2    Wahl, G.M.3
  • 71
    • 0029856557 scopus 로고    scopus 로고
    • Three distinct signalling responses by murine fibroblasts to genotoxic stress
    • Liu, Z. G., Baskaran, R., Lea-Chou, E. T., Wood, L. D., Chen, Y., Karin, M., and Wang, J. Y. 1996. Three distinct signalling responses by murine fibroblasts to genotoxic stress. Nature. 384:273-276.
    • (1996) Nature , vol.384 , pp. 273-276
    • Liu, Z.G.1    Baskaran, R.2    Lea-Chou, E.T.3    Wood, L.D.4    Chen, Y.5    Karin, M.6    Wang, J.Y.7
  • 72
    • 0033574434 scopus 로고    scopus 로고
    • Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents
    • Gibson, S., Widmann, C., and Johnson, G. L. 1999. Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents. J Biol Chem. 274:10916-10922.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10916-10922
    • Gibson, S.1    Widmann, C.2    Johnson, G.L.3
  • 74
    • 0033485261 scopus 로고    scopus 로고
    • Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
    • Bulavin, D. V., Saito, S., Hollander, M. C., Sakaguchi, K., Anderson, C. W., Appella, E., and Fornace, A. J., Jr. 1999. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO. J. 18:6845-6854.
    • (1999) EMBO. J. , vol.18 , pp. 6845-6854
    • Bulavin, D.V.1    Saito, S.2    Hollander, M.C.3    Sakaguchi, K.4    Anderson, C.W.5    Appella, E.6    Fornace A.J., Jr.7
  • 75
    • 0034617077 scopus 로고    scopus 로고
    • ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation
    • She, Q. B., Chen, N., and Dong, Z. 2000. ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation. J. Biol. Chem. 275:20444-20449.
    • (2000) J. Biol. Chem. , vol.275 , pp. 20444-20449
    • She, Q.B.1    Chen, N.2    Dong, Z.3
  • 76
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia, Z., Dickens, M., Raingeaud, J., Davis, R. J., and Greenberg, M. E. 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 270:1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 78
    • 0030694175 scopus 로고    scopus 로고
    • Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons
    • Philpott, K. L., McCarthy, M. J., Klippel, A., and Rubin, L. L. 1997. Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons. J. Cell Biol. 139:809-815.
    • (1997) J. Cell Biol. , vol.139 , pp. 809-815
    • Philpott, K.L.1    McCarthy, M.J.2    Klippel, A.3    Rubin, L.L.4
  • 79
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 80
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
    • Zha, J., Harada, H., Yang, E., Jockel, J., and Korsmeyer, S. J. 1996. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L). Cell. 87:619-628.
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5
  • 82
    • 0033571906 scopus 로고    scopus 로고
    • Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway
    • Mazzoni, I. E., Said, F. A., Aloyz, R., Miller, F. D., and Kaplan, D. 1999. Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway. J. Neurosci. 19:9716-9727.
    • (1999) J. Neurosci. , vol.19 , pp. 9716-9727
    • Mazzoni, I.E.1    Said, F.A.2    Aloyz, R.3    Miller, F.D.4    Kaplan, D.5
  • 83
  • 84
    • 0034985847 scopus 로고    scopus 로고
    • p53 protein at the hub of cellular DNA damage response pathways through sequencespecific and non-sequence-specific DNA binding
    • Liu, Y. and Kulesz-Martin M. 2001. p53 protein at the hub of cellular DNA damage response pathways through sequencespecific and non-sequence-specific DNA binding. Carcinogenesis. 22:851-860.
    • (2001) Carcinogenesis , vol.22 , pp. 851-860
    • Liu, Y.1    Kulesz-Martin, M.2
  • 86
    • 0033044728 scopus 로고    scopus 로고
    • The involvement of p53 in dopamine-induced apoptosis of cerebellar granule neurons and leukemic cells overexpressing p53
    • Daily, D., Barzilai, A., Offen, D., Kamsler, A., Melamed, E., and Ziv, I. 1999. The involvement of p53 in dopamine-induced apoptosis of cerebellar granule neurons and leukemic cells overexpressing p53. Cell Mol. Neurobiol. 19:261-276.
    • (1999) Cell Mol. Neurobiol. , vol.19 , pp. 261-276
    • Daily, D.1    Barzilai, A.2    Offen, D.3    Kamsler, A.4    Melamed, E.5    Ziv, I.6
  • 87
    • 0035448927 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated-dependent apoptosis after genotoxic stress in the developing nervous system is determined by cellular differentiation status
    • Lee, Y., Chong, M. J., and McKinnon, P. J. 2001. Ataxia telangiectasia mutated-dependent apoptosis after genotoxic stress in the developing nervous system is determined by cellular differentiation status. J. Neurosci. 21:6687-6693.
    • (2001) J. Neurosci. , vol.21 , pp. 6687-6693
    • Lee, Y.1    Chong, M.J.2    McKinnon, P.J.3
  • 88
    • 0033534665 scopus 로고    scopus 로고
    • Status epilepticus induces p53 sequence-specific DNA binding in mature rat brain
    • Liu, W., Rong, Y., Baudry, M., and Schreiber, S. S. 1999. Status epilepticus induces p53 sequence-specific DNA binding in mature rat brain. Brain Res. Mol. Brain Res. 63:248-253.
    • (1999) Brain Res. Mol. Brain Res. , vol.63 , pp. 248-253
    • Liu, W.1    Rong, Y.2    Baudry, M.3    Schreiber, S.S.4
  • 90
    • 0034689773 scopus 로고    scopus 로고
    • Role of NF-kappaB in p53-mediated programmed cell death
    • Ryan, K. M., Ernst, M. K., Rice, N. R., and Vousden, K. H. 2000. Role of NF-kappaB in p53-mediated programmed cell death. Nature. 404:892-897.
    • (2000) Nature , vol.404 , pp. 892-897
    • Ryan, K.M.1    Ernst, M.K.2    Rice, N.R.3    Vousden, K.H.4
  • 91
    • 0032557889 scopus 로고    scopus 로고
    • Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats
    • Nonaka, S. and Chuang, D. M. 1998. Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats. Neuroreport. 9:2081-2084.
    • (1998) Neuroreport , vol.9 , pp. 2081-2084
    • Nonaka, S.1    Chuang, D.M.2
  • 92
    • 0033595020 scopus 로고    scopus 로고
    • Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis
    • Xu, X., Yang, D., Wyss-Coray, T., Yan, J., Gan, L., Sun, Y., and Mucke, L. 1999. Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis. Proc. Natl. Acad. Sci. U.S.A. 96:7547-7552.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 7547-7552
    • Xu, X.1    Yang, D.2    Wyss-Coray, T.3    Yan, J.4    Gan, L.5    Sun, Y.6    Mucke, L.7
  • 93
    • 85047697335 scopus 로고    scopus 로고
    • A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes
    • Thornborrow, E. C., Patel, S., Mastropietro, A. E., Schwartzfarb, E. M., and Manfredi, J. J. 2002. A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes. Oncogene. 21:990-999.
    • (2002) Oncogene , vol.21 , pp. 990-999
    • Thornborrow, E.C.1    Patel, S.2    Mastropietro, A.E.3    Schwartzfarb, E.M.4    Manfredi, J.J.5
  • 95
    • 0030689782 scopus 로고    scopus 로고
    • The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo
    • Reinke, V. and Lozano, G. 1997. The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo. Oncogene. 15:1527-1534.
    • (1997) Oncogene , vol.15 , pp. 1527-1534
    • Reinke, V.1    Lozano, G.2
  • 98
    • 0034737292 scopus 로고    scopus 로고
    • Drosophila p53 binds a damage response element at the reaper locus
    • Brodsky, M. H., Nordstrom, W., Tsang, G., Kwan, E., Rubin, G. M., and Abrams, J. M. 2000. Drosophila p53 binds a damage response element at the reaper locus. Cell. 101:103-113.
    • (2000) Cell , vol.101 , pp. 103-113
    • Brodsky, M.H.1    Nordstrom, W.2    Tsang, G.3    Kwan, E.4    Rubin, G.M.5    Abrams, J.M.6
  • 99
    • 0031036879 scopus 로고    scopus 로고
    • The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal
    • Prisco, M., Hongo, A., Rizzo, M. G., Sacchi, A., and Baserga, R. 1997. The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal. Mol. Cell Biol. 17:1084-1092.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 1084-1092
    • Prisco, M.1    Hongo, A.2    Rizzo, M.G.3    Sacchi, A.4    Baserga, R.5
  • 100
    • 0029803281 scopus 로고    scopus 로고
    • Wild-type p53 negatively regulates the expression of a microtubule-associated protein
    • Murphy, M., Hinman, A., and Levine, A. J. 1996. Wild-type p53 negatively regulates the expression of a microtubule-associated protein. Genes Dev. 10:2971-2980.
    • (1996) Genes Dev. , vol.10 , pp. 2971-2980
    • Murphy, M.1    Hinman, A.2    Levine, A.J.3
  • 101
    • 0033229866 scopus 로고    scopus 로고
    • p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
    • Li, P. F., Dietz, R., and von Harsdorf, R. 1999. p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. EMBO. J. 18:6027-6036.
    • (1999) EMBO. J. , vol.18 , pp. 6027-6036
    • Li, P.F.1    Dietz, R.2    Von Harsdorf, R.3
  • 102
    • 0027485950 scopus 로고
    • Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor
    • Deckwerth, T. L. and Johnson, E. M., Jr. 1993. Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. J. Cell Biol. 123:1207-1222.
    • (1993) J. Cell Biol. , vol.123 , pp. 1207-1222
    • Deckwerth, T.L.1    Johnson E.M., Jr.2
  • 103
    • 0028046038 scopus 로고
    • Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40
    • Vayssiere, J. L., Petit, P. X., Risler, Y., and Mignotte, B. 1994. Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc. Natl. Acad. Sci. U.S.A. 91:11752-11756.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 11752-11756
    • Vayssiere, J.L.1    Petit, P.X.2    Risler, Y.3    Mignotte, B.4
  • 104
    • 0028903933 scopus 로고
    • Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
    • Zamzami, N., Marchetti, P., Castedo, M., Zanin, C., Vayssiere, J. L., Petit, P. X., and Kroemer, G. 1995. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med. 181:1661-1672.
    • (1995) J. Exp. Med. , vol.181 , pp. 1661-1672
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3    Zanin, C.4    Vayssiere, J.L.5    Petit, P.X.6    Kroemer, G.7
  • 105
    • 0029036412 scopus 로고
    • Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis
    • Petit, P. X., Lecoeur, H., Zorn, E., Dauguet, C., Mignotte, B., and Gougeon, M. L. 1995. Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J. Cell Biol. 130:157-167.
    • (1995) J. Cell Biol. , vol.130 , pp. 157-167
    • Petit, P.X.1    Lecoeur, H.2    Zorn, E.3    Dauguet, C.4    Mignotte, B.5    Gougeon, M.L.6
  • 107
    • 0029906828 scopus 로고    scopus 로고
    • BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases
    • Xiang, J., Chao, D. T., and Korsmeyer, S. J. 1996. BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. Proc. Natl. Acad. Sci. U.S.A. 93: 14559-14563.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 14559-14563
    • Xiang, J.1    Chao, D.T.2    Korsmeyer, S.J.3
  • 110
    • 0033010059 scopus 로고    scopus 로고
    • Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis
    • McGinnis, K. M., Gnegy, M. E., and Wang, K. K. 1999. Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis. J. Neurochem. 72:1899-1906.
    • (1999) J. Neurochem. , vol.72 , pp. 1899-1906
    • McGinnis, K.M.1    Gnegy, M.E.2    Wang, K.K.3
  • 111
    • 0033198217 scopus 로고    scopus 로고
    • BAX translocation is a critical event in neuronal apoptosis: Regulation by neuroprotectants, BCL-2, and caspases
    • Putcha, G. V., Deshmukh, M., and Johnson, E. M., Jr. 1999. BAX translocation is a critical event in neuronal apoptosis: Regulation by neuroprotectants, BCL-2, and caspases. J. Neurosci. 19:7476-7485.
    • (1999) J. Neurosci. , vol.19 , pp. 7476-7485
    • Putcha, G.V.1    Deshmukh, M.2    Johnson E.M., Jr.3
  • 112
    • 0031001244 scopus 로고    scopus 로고
    • Bax promotes neuronal cell death and is downregulated during the development of the nervous system
    • Vekrellis, K., McCarthy, M. J., Watson, A., Whitfield, J., Rubin, L. L., and Ham, J. 1997. Bax promotes neuronal cell death and is downregulated during the development of the nervous system. Development. 124:1239-1249.
    • (1997) Development , vol.124 , pp. 1239-1249
    • Vekrellis, K.1    McCarthy, M.J.2    Watson, A.3    Whitfield, J.4    Rubin, L.L.5    Ham, J.6
  • 113
    • 0032484687 scopus 로고    scopus 로고
    • Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons
    • Martinou, I., Missotten, M., Fernandez, P. A., Sadoul, R., and Martinou. J. C. 1998. Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons. Neuroreport. 9:15-19.
    • (1998) Neuroreport , vol.9 , pp. 15-19
    • Martinou, I.1    Missotten, M.2    Fernandez, P.A.3    Sadoul, R.4    Martinou, J.C.5
  • 115
    • 0034629291 scopus 로고    scopus 로고
    • p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release
    • Schuler, M., Bossy-Wetzel, E., Goldstein, J. C., Fitzgerald, P., and Green, D. R. 2000. p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release. J. Biol. Chem. 275:7337-7342.
    • (2000) J. Biol. Chem. , vol.275 , pp. 7337-7342
    • Schuler, M.1    Bossy-Wetzel, E.2    Goldstein, J.C.3    Fitzgerald, P.4    Green, D.R.5
  • 117
    • 0034710940 scopus 로고    scopus 로고
    • Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria
    • Deng, Y. and Wu, X. 2000. Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria. Proc. Natl. Acad. Sci. U.S.A. 97:12050-12055.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 12050-12055
    • Deng, Y.1    Wu, X.2
  • 121
    • 0035736259 scopus 로고    scopus 로고
    • Organelle-specific initiation of cell death pathways
    • Ferri, K. F. and Kroemer, G. 2001. Organelle-specific initiation of cell death pathways. Nat. Cell Biol. 3:E255-E263.
    • (2001) Nat. Cell Biol. , vol.3
    • Ferri, K.F.1    Kroemer, G.2
  • 123
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A. J. 1997. p53, the cellular gatekeeper for growth and division. Cell. 88:323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 124
    • 0032931517 scopus 로고    scopus 로고
    • The p53 pathway
    • Prives, C. and Hall, P. A. 1999. The p53 pathway. J. Pathol. 187:112-126.
    • (1999) J. Pathol. , vol.187 , pp. 112-126
    • Prives, C.1    Hall, P.A.2
  • 127
    • 0034079520 scopus 로고    scopus 로고
    • The p53/p63/p73 family of transcription factors: Overlapping and distinct functions
    • Levrero, M., De Laurenzi, V., Costanzo, A., Gong, J., Wang, J. Y., and Melino, G. 2000. The p53/p63/p73 family of transcription factors: Overlapping and distinct functions. J. Cell Sci. 113:1661-1670.
    • (2000) J. Cell Sci. , vol.113 , pp. 1661-1670
    • Levrero, M.1    De Laurenzi, V.2    Costanzo, A.3    Gong, J.4    Wang, J.Y.5    Melino, G.6
  • 128
    • 0034192628 scopus 로고    scopus 로고
    • Regulation and function of the p53-related proteins: Same family, different rules
    • Lohrum, M. A. and Vousden, K. H. 2000. Regulation and function of the p53-related proteins: Same family, different rules. Trends Cell Biol. 10:197-202.
    • (2000) Trends Cell Biol. , vol.10 , pp. 197-202
    • Lohrum, M.A.1    Vousden, K.H.2
  • 129
    • 0034647718 scopus 로고    scopus 로고
    • An anti-apoptotic role for the p53 family member, p73, during developmental neuron death
    • Pozniak, C. D., Radinovic, S., Yang, A., McKeon, F., Kaplan, D. R., and Miller, F. D. 2000. An anti-apoptotic role for the p53 family member, p73, during developmental neuron death. Science. 289:304-306.
    • (2000) Science , vol.289 , pp. 304-306
    • Pozniak, C.D.1    Radinovic, S.2    Yang, A.3    McKeon, F.4    Kaplan, D.R.5    Miller, F.D.6
  • 130
    • 0028641624 scopus 로고
    • Tumor suppressor p53 induction and DNA damage in hippocampal granule cells after adrenalectomy
    • Schreiber, S. S., Sakhi, S., Dugich-Djordjevic, M. M., and Nichols, N. R. 1994. Tumor suppressor p53 induction and DNA damage in hippocampal granule cells after adrenalectomy. Exp. Neurol. 130:368-376.
    • (1994) Exp. Neurol. , vol.130 , pp. 368-376
    • Schreiber, S.S.1    Sakhi, S.2    Dugich-Djordjevic, M.M.3    Nichols, N.R.4
  • 133
    • 0028263192 scopus 로고
    • p53-immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats
    • discussion 855-856
    • Li, Y., Chopp, M., Zhang, Z. G., Zaloga, C., Niewenhuis, L., and Gautam, S. 1994. p53-immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats. Stroke. 25:849-855; discussion 855-856.
    • (1994) Stroke , vol.25 , pp. 849-855
    • Li, Y.1    Chopp, M.2    Zhang, Z.G.3    Zaloga, C.4    Niewenhuis, L.5    Gautam, S.6
  • 134
    • 0032893772 scopus 로고    scopus 로고
    • The tumor suppressor p53 and its response gene p21WAF1/Cip1 are not markers of neuronal death following transient global cerebral ischemia
    • Tomasevic, G., Kamme, F., Stubberod, P., Wieloch, M., and Wieloch, T. 1999. The tumor suppressor p53 and its response gene p21WAF1/Cip1 are not markers of neuronal death following transient global cerebral ischemia. Neuroscience. 90:781-792.
    • (1999) Neuroscience , vol.90 , pp. 781-792
    • Tomasevic, G.1    Kamme, F.2    Stubberod, P.3    Wieloch, M.4    Wieloch, T.5
  • 136
    • 0028567078 scopus 로고
    • Photochemical brain injury in rats triggers DNA fragmentation, p53 and HSP72
    • Manev, H., Kharlamov, A., and Armstrong, D. M. 1994. Photochemical brain injury in rats triggers DNA fragmentation, p53 and HSP72. Neuroreport. 5:2661-2664.
    • (1994) Neuroreport , vol.5 , pp. 2661-2664
    • Manev, H.1    Kharlamov, A.2    Armstrong, D.M.3
  • 137
    • 0030272509 scopus 로고    scopus 로고
    • Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation
    • Hughes, P. E., Alexi, T., Yoshida, T., Schreiber, S. S., and Knusel, B. 1996. Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation. Neuroscience. 74:1143-1160.
    • (1996) Neuroscience , vol.74 , pp. 1143-1160
    • Hughes, P.E.1    Alexi, T.2    Yoshida, T.3    Schreiber, S.S.4    Knusel, B.5
  • 138
    • 0033528230 scopus 로고    scopus 로고
    • Apoptosis and expression of p53 response proteins and cyclin D1 after cortical impact in rat brain
    • Kaya, S. S., Mahmood, A., Li, Y., Yavuz, E., Goksel, M., and Chopp, M. 1999. Apoptosis and expression of p53 response proteins and cyclin D1 after cortical impact in rat brain. Brain Res. 818:23-33.
    • (1999) Brain Res. , vol.818 , pp. 23-33
    • Kaya, S.S.1    Mahmood, A.2    Li, Y.3    Yavuz, E.4    Goksel, M.5    Chopp, M.6
  • 139
    • 0030956532 scopus 로고    scopus 로고
    • p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PCl2 cells
    • Blum, D., Wu, Y., Nissou, M. F., Arnaud, S., Alim Louis, B., and Verna, J. M. 1997. p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PCl2 cells. Brain Res. 751:139-142.
    • (1997) Brain Res. , vol.751 , pp. 139-142
    • Blum, D.1    Wu, Y.2    Nissou, M.F.3    Arnaud, S.4    Alim Louis, B.5    Verna, J.M.6
  • 140
    • 0030887853 scopus 로고    scopus 로고
    • Genetic determinants of susceptibility to excitotoxic cell death: Implications for gene targeting approaches
    • Schauwecker, P. E. and Steward, O. 1997. Genetic determinants of susceptibility to excitotoxic cell death: Implications for gene targeting approaches. Proc. Natl. Acad. Sci. U.S.A. 94: 4103-4108.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 4103-4108
    • Schauwecker, P.E.1    Steward, O.2
  • 142
    • 0029670172 scopus 로고    scopus 로고
    • p53 protein in sympathetic neurons: Cytoplasmic localization and no apparent function in apoptosis
    • Sadoul, R., Quiquerez, A. L., Martinou, I., Fernandez, P. A., and Martinou, J. C. 1996. p53 protein in sympathetic neurons: Cytoplasmic localization and no apparent function in apoptosis. J. Neurosci. Res. 43:594-601.
    • (1996) J. Neurosci. Res. , vol.43 , pp. 594-601
    • Sadoul, R.1    Quiquerez, A.L.2    Martinou, I.3    Fernandez, P.A.4    Martinou, J.C.5
  • 143
    • 0027940391 scopus 로고
    • Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins
    • Davies, A. M. and Rosenthal, A. 1994. Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins. Neurosci. Lett. 182:112-114.
    • (1994) Neurosci. Lett. , vol.182 , pp. 112-114
    • Davies, A.M.1    Rosenthal, A.2


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