Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 34, 2004, Pages 12467-12472

  Fellouse, Frederic A ^a   Wiesmann, Christian ^a   Sidhu, Sachdev S ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; ANTIBODY; ASPARTIC ACID; IMMUNOGLOBULIN F(AB) FRAGMENT; SERINE; SOLVENT; TYROSINE; VASCULOTROPIN;

ANTIBODY LIBRARY; ANTIGEN ANTIBODY COMPLEX; ANTIGEN RECOGNITION; ARTICLE; BINDING SITE; CODON; COMPLEMENTARITY DETERMINING REGION; HUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN CONFORMATION;

AMINO ACID SEQUENCE; ANTIGENS; BINDING SITES; BINDING SITES, ANTIBODY; CODON; COMPLEMENTARITY DETERMINING REGIONS; CRYSTALLOGRAPHY, X-RAY; EPITOPES; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; TYROSINE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 4344714933     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0401786101     Document Type: Article

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