Crystal structure of anti-hen egg white lysozyme antibody (HyHEL-10) Fv- antigen complex. Local structural changes in the protein antigen and water- mediated interactions of Fv-antigen and light chain-heavy chain interfaces

Journal of Biological Chemistry

Volumn 274, Issue 39, 1999, Pages 27623-27631

  Kondo, Hidemasa ^a,c   Shiroishi, Mitsunori ^a   Matsushima, Masaaki ^b   Tsumoto, Kouhei ^a   Kumagai, Izumi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b Rational Drug Design Laboratories   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTIGEN; LYSOZYME;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CRYSTAL STRUCTURE; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES, ANTIBODY; CHICKENS; CRYSTALLOGRAPHY, X-RAY; EGG WHITE; HYDROGEN BONDING; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MURAMIDASE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; WATER;

EID: 0033600742     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.39.27623     Document Type: Article

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