Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme

Biochemistry

Volumn 35, Issue 48, 1996, Pages 15494-15503

  Fields, Barry A ^a   Goldbaum, Fernando A ^a   Acqua, William Dall' ^a   Malchiodi, Emilio L ^a,b   Cauerhff, Ana ^a   Schwarz, Frederick P ^a   Ysern, Xavier ^c   Poljak, Roberte J ^a   Mariuzza, Roy A ^a  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CRYSTAL STRUCTURE; ENTROPY; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; THERMODYNAMICS;

ANTIGEN-ANTIBODY COMPLEX; CALORIMETRY; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; IMMUNOGLOBULIN VARIABLE REGION; MODELS, MOLECULAR; MURAMIDASE; MUTAGENESIS, SITE-DIRECTED;

EID: 0029856410     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961709e     Document Type: Article

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