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Volumn 42, Issue 4, 2007, Pages 358-365

Recent advances in the biosynthesis of taxol

Author keywords

Biosynthetic pathway; Combinational expression; Taxol

Indexed keywords

ANTINEOPLASTIC AGENT; DOCETAXEL; PACLITAXEL; TAXOID;

EID: 34249948813     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (47)
  • 1
    • 34249932597 scopus 로고    scopus 로고
    • Recent advance in studies on production of taxol with biological technology [J]
    • Ye JY, Gao F. Recent advance in studies on production of taxol with biological technology [J]. J Guizhou Univ (Nat Sci). 1998, 15:139 - 144.
    • (1998) J Guizhou Univ (Nat Sci) , vol.15 , pp. 139-144
    • Ye, J.Y.1    Gao, F.2
  • 2
    • 3142631984 scopus 로고    scopus 로고
    • Advances in taxol research [J]
    • Shen ZW, Wu LF. Advances in taxol research [J]. Prog Chem, 1997, 9:1 - 13.
    • (1997) Prog Chem , vol.9 , pp. 1-13
    • Shen, Z.W.1    Wu, L.F.2
  • 3
    • 0029156949 scopus 로고
    • Crystal and molecular structure of paclitaxel (taxol) [J]
    • Mastropaolo D, Camerman A, Luo Y, et al. Crystal and molecular structure of paclitaxel (taxol) [J]. Proc Natl Acad Sci USA, 1995, 92:6920 - 6924.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6920-6924
    • Mastropaolo, D.1    Camerman, A.2    Luo, Y.3
  • 4
    • 0037365310 scopus 로고    scopus 로고
    • A structure-activity study of taxol, laxotere, and derivatives using the electronic indices methodology (EIM) [J]
    • Braga SF, Galvao DS. A structure-activity study of taxol, laxotere, and derivatives using the electronic indices methodology (EIM) [J]. J Chem Inf Comput Sci, 2003, 43:699 - 706.
    • (2003) J Chem Inf Comput Sci , vol.43 , pp. 699-706
    • Braga, S.F.1    Galvao, D.S.2
  • 5
    • 0037184831 scopus 로고    scopus 로고
    • Synthesis of C-3' methyl taxotere (docetaxel) [J]
    • Lucatelli C, Viton F, Gimbert Y, et al. Synthesis of C-3' methyl taxotere (docetaxel) [J]. J Org Chem, 2002, 67:9468 - 9470.
    • (2002) J Org Chem , vol.67 , pp. 9468-9470
    • Lucatelli, C.1    Viton, F.2    Gimbert, Y.3
  • 6
    • 34249942314 scopus 로고    scopus 로고
    • Lin GS, Cheng HH, Fu ZC. Concurrent chemoradiotherapy with low dose weekly paclitaxel in the treatment of stage III non-small-cell lung cancer [J]. China Oncol, 2006, 16:277 - 280.
    • Lin GS, Cheng HH, Fu ZC. Concurrent chemoradiotherapy with low dose weekly paclitaxel in the treatment of stage III non-small-cell lung cancer [J]. China Oncol, 2006, 16:277 - 280.
  • 7
    • 34249948668 scopus 로고    scopus 로고
    • Clinical research of dose-dense combinated pharmorubicin with paclitaxel in advanced breast cancer treatment [J]
    • Zeng XH, Zhou HW, Wang JJ, et al. Clinical research of dose-dense combinated pharmorubicin with paclitaxel in advanced breast cancer treatment [J]. J Chongqing Med Univ, 2005, 30:873 - 877.
    • (2005) J Chongqing Med Univ , vol.30 , pp. 873-877
    • Zeng, X.H.1    Zhou, H.W.2    Wang, J.J.3
  • 8
    • 34249942830 scopus 로고    scopus 로고
    • Preliminary clinical observation of paclitaxel based chemotherapy in the treatment of advanced gastric cancer [J]
    • Zhong XM, Huang WB. Preliminary clinical observation of paclitaxel based chemotherapy in the treatment of advanced gastric cancer [J]. J Mod Oncol, 2006, 14:203 - 204.
    • (2006) J Mod Oncol , vol.14 , pp. 203-204
    • Zhong, X.M.1    Huang, W.B.2
  • 9
    • 34249951454 scopus 로고    scopus 로고
    • Nosocomial infection during radiotherapy with concomitant weekly paclitaxel for advanced nasopharyngeal carcinoma: A clinical investigation [J]
    • Ding WJ, Wang JH, Yang HH, et al. Nosocomial infection during radiotherapy with concomitant weekly paclitaxel for advanced nasopharyngeal carcinoma: a clinical investigation [J]. Chin J Nosocomiol, 2006, 16:398 - 400.
    • (2006) Chin J Nosocomiol , vol.16 , pp. 398-400
    • Ding, W.J.1    Wang, J.H.2    Yang, H.H.3
  • 10
    • 34249945111 scopus 로고    scopus 로고
    • Comparison between paclitaxel plus carboplatin and paclitaxel plua cisplatin in the treatment of advanced stage of ovarian cancer [J]
    • Xiang HY, Shen GH. Comparison between paclitaxel plus carboplatin and paclitaxel plua cisplatin in the treatment of advanced stage of ovarian cancer [J]. Chin J Clin Oncol Rehabil, 2006, 13:165 - 167.
    • (2006) Chin J Clin Oncol Rehabil , vol.13 , pp. 165-167
    • Xiang, H.Y.1    Shen, G.H.2
  • 11
    • 34249949242 scopus 로고    scopus 로고
    • Clinical efficacy of docetaxel plus nedaplatin for advanced cervical cancer [J]
    • Peng JW, Liang HL, Xiao JJ, et al. Clinical efficacy of docetaxel plus nedaplatin for advanced cervical cancer [J]. Chin J Clin Oncol Rehabil, 2006, 13:114 - 116.
    • (2006) Chin J Clin Oncol Rehabil , vol.13 , pp. 114-116
    • Peng, J.W.1    Liang, H.L.2    Xiao, J.J.3
  • 12
    • 34248519206 scopus 로고    scopus 로고
    • The study of antiproliferation agent paclitaxel on preventing graft arteriosclerosis [J]. Fudan Univ
    • Yang ZH, Hong T, Wang CS, et al. The study of antiproliferation agent paclitaxel on preventing graft arteriosclerosis [J]. Fudan Univ J Med Sci, 2006, 33:225 - 228.
    • (2006) J Med Sci , vol.33 , pp. 225-228
    • Yang, Z.H.1    Hong, T.2    Wang, C.S.3
  • 13
    • 84966691338 scopus 로고    scopus 로고
    • Application of paclitaxel in glaucoma filtration surgery [J]
    • Ren YX, Wei YC, Zhao F. Application of paclitaxel in glaucoma filtration surgery [J]. J Diffic Complicat Case, 2005, 4:328 - 330.
    • (2005) J Diffic Complicat Case , vol.4 , pp. 328-330
    • Ren, Y.X.1    Wei, Y.C.2    Zhao, F.3
  • 14
    • 34249936068 scopus 로고    scopus 로고
    • Ying M, Chen LB, Geng HC, et al. An experimental study of paclitaxol on inhibiting angiogenesis [J]. Cancer Res Prev Treat, 2004, 31:282 - 285.
    • Ying M, Chen LB, Geng HC, et al. An experimental study of paclitaxol on inhibiting angiogenesis [J]. Cancer Res Prev Treat, 2004, 31:282 - 285.
  • 15
    • 34249942964 scopus 로고    scopus 로고
    • http://www.zghds.cn/jianjie.asp[DB/OL].
    • http://www.zghds.cn/jianjie.asp[DB/OL].
  • 16
    • 34249935580 scopus 로고    scopus 로고
    • http://www.hongdoushanonline.com/js.htm[DB/OL].
    • http://www.hongdoushanonline.com/js.htm[DB/OL].
  • 17
    • 34249934750 scopus 로고    scopus 로고
    • http://www.hongdoushanonline.com/yyjzg. htm [DB/OL].
    • http://www.hongdoushanonline.com/yyjzg. htm [DB/OL].
  • 18
    • 0028213668 scopus 로고
    • First total synthesis of taxol. 1. Functionalization of the B ring [J]
    • Holton RA, Somoza C, Kim HB, et al. First total synthesis of taxol. 1. Functionalization of the B ring [J]. J Am Chem Soc, 1994, 116:1597 - 1598.
    • (1994) J Am Chem Soc , vol.116 , pp. 1597-1598
    • Holton, R.A.1    Somoza, C.2    Kim, H.B.3
  • 19
    • 0028353983 scopus 로고
    • First total synthesis of taxol. 2. Completion of the C and D rings [J]
    • Holton RA, Kim HB, Somoza C, et al. First total synthesis of taxol. 2. Completion of the C and D rings [J]. J Am Chem Soc, 1994, 116:1599 - 1600.
    • (1994) J Am Chem Soc , vol.116 , pp. 1599-1600
    • Holton, R.A.1    Kim, H.B.2    Somoza, C.3
  • 20
    • 0028012837 scopus 로고
    • Total synthesis of taxol [J]
    • Nicolaou KC, Yang Z, Liu JJ, et al. Total synthesis of taxol [J]. Nature, 1994, 367:630 - 634.
    • (1994) Nature , vol.367 , pp. 630-634
    • Nicolaou, K.C.1    Yang, Z.2    Liu, J.J.3
  • 21
    • 0035656798 scopus 로고    scopus 로고
    • Total synthesis of taxol developed by nicolaou [J]
    • Xu L, Wang FP. Total synthesis of taxol developed by nicolaou [J]. Chin J Org Chem, 2001, 21: 493 - 504.
    • (2001) Chin J Org Chem , vol.21 , pp. 493-504
    • Xu, L.1    Wang, F.P.2
  • 22
    • 0036252577 scopus 로고    scopus 로고
    • Production of paclitaxel and baccatin III in a 20-L airlift bioreactor by a cell suspension of Taxus wallichiana [J]
    • Navia-Osorio A, Garden H, Cusido RM, et al. Production of paclitaxel and baccatin III in a 20-L airlift bioreactor by a cell suspension of Taxus wallichiana [J]. Planta Med, 2002, 68:336 - 340.
    • (2002) Planta Med , vol.68 , pp. 336-340
    • Navia-Osorio, A.1    Garden, H.2    Cusido, R.M.3
  • 23
    • 0027270462 scopus 로고
    • Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew [J]
    • Stierle A, Strobel G, Stierle D. Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew [J]. Science, 1993, 260:214 - 216.
    • (1993) Science , vol.260 , pp. 214-216
    • Stierle, A.1    Strobel, G.2    Stierle, D.3
  • 24
    • 33745499256 scopus 로고    scopus 로고
    • Taxol-producing fungi: A new approach to industrial production of taxol [J]
    • Ji Y, Bi JN, Yan B, et al. Taxol-producing fungi: a new approach to industrial production of taxol [J]. Chin J Biotechnol, 2006, 22:1 - 6.
    • (2006) Chin J Biotechnol , vol.22 , pp. 1-6
    • Ji, Y.1    Bi, J.N.2    Yan, B.3
  • 25
    • 0001668372 scopus 로고
    • Isolation of an endophytic fungus associated with Taxus yunnanensis etl. k. Fu [J]
    • Qiu DY, Huang MJ, Fang XH, et al. Isolation of an endophytic fungus associated with Taxus yunnanensis etl. k. Fu [J]. Acta Mycol Sin, 1994, 13: 314-316.
    • (1994) Acta Mycol Sin , vol.13 , pp. 314-316
    • Qiu, D.Y.1    Huang, M.J.2    Fang, X.H.3
  • 26
    • 33645573250 scopus 로고    scopus 로고
    • Genetic engineering of taxol biosyntheticGenes in Saccharomyces ccrevisiae [J]
    • Dejong JM, Liu YL, Bollon AP, et al. Genetic engineering of taxol biosyntheticGenes in Saccharomyces ccrevisiae [J]. Biotechol Bioeng, 2006, 93:212 - 224.
    • (2006) Biotechol Bioeng , vol.93 , pp. 212-224
    • Dejong, J.M.1    Liu, Y.L.2    Bollon, A.P.3
  • 27
    • 15944383707 scopus 로고    scopus 로고
    • Coexpression in yeast of Taxus cytochrome P450 reductase with cytochrome P450 oxygenases involved in taxol biosynthesis [J]
    • Jennewein S, Park H, Dejong JM, et al. Coexpression in yeast of Taxus cytochrome P450 reductase with cytochrome P450 oxygenases involved in taxol biosynthesis [J]. Biotechnol Bioeng, 2005, 89:588 - 598.
    • (2005) Biotechnol Bioeng , vol.89 , pp. 588-598
    • Jennewein, S.1    Park, H.2    Dejong, J.M.3
  • 28
    • 34249936067 scopus 로고    scopus 로고
    • Preliminary study on metabolic engineering of yeast for producing taxadiene [J]
    • Wang W, Meng C, Zhu P, et al. Preliminary study on metabolic engineering of yeast for producing taxadiene [J]. Chin Biotechnol, 2005, 25: 103 - 108.
    • (2005) Chin Biotechnol , vol.25 , pp. 103-108
    • Wang, W.1    Meng, C.2    Zhu, P.3
  • 29
    • 0032422236 scopus 로고    scopus 로고
    • Cloning and functional expression of a cDNA encoding geranylgeranyl diphosphate synthese from Taxus canadensis and assessment of the role of this prenyltransferase in cells induced for taxol production [J]
    • Hefner J, Ketchum RE, Croteau R. Cloning and functional expression of a cDNA encoding geranylgeranyl diphosphate synthese from Taxus canadensis and assessment of the role of this prenyltransferase in cells induced for taxol production [J]. Arch Biochem Biophys, 1998, 360:62 - 74.
    • (1998) Arch Biochem Biophys , vol.360 , pp. 62-74
    • Hefner, J.1    Ketchum, R.E.2    Croteau, R.3
  • 30
    • 0029087870 scopus 로고    scopus 로고
    • Hezari M, Lewis NG, Croteau R. Purification and characterization of taxa-4 (5), 11 (12)-diene synthase from Pacific yew (Taxus brevifolia) that catalyzes the first committed step of taxol biosynthesis [J]. Arch Biochem Biophys, 1995, 322:437 - 444.
    • Hezari M, Lewis NG, Croteau R. Purification and characterization of taxa-4 (5), 11 (12)-diene synthase from Pacific yew (Taxus brevifolia) that catalyzes the first committed step of taxol biosynthesis [J]. Arch Biochem Biophys, 1995, 322:437 - 444.
  • 31
    • 0029873176 scopus 로고    scopus 로고
    • A cDNA clone for taxadiene synthase, the diterpene cyclase that catalyzes the committed step of taxol biosynthesis [J]
    • Mark R. Wildung MR, Croteau R. A cDNA clone for taxadiene synthase, the diterpene cyclase that catalyzes the committed step of taxol biosynthesis [J]. J Biol Chem, 1996, 271:9201 - 9204.
    • (1996) J Biol Chem , vol.271 , pp. 9201-9204
    • Mark, R.1    Wildung, M.R.2    Croteau, R.3
  • 32
    • 2642518854 scopus 로고    scopus 로고
    • Cytochrome P450 taxadiene 5α-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis [J]
    • Jennewein S, Long RM, Williams RM, et al. Cytochrome P450 taxadiene 5α-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis [J]. Chem Biol, 2004, 11:379 - 387.
    • (2004) Chem Biol , vol.11 , pp. 379-387
    • Jennewein, S.1    Long, R.M.2    Williams, R.M.3
  • 33
    • 0034652139 scopus 로고    scopus 로고
    • Walker K, Schoendorf A, Croteau R. Molecular Cloning of a taxa-4 (20), 11(12) -dien-5α-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli [J]. Arch Biochem Biophys, 2000, 374:371 - 380.
    • Walker K, Schoendorf A, Croteau R. Molecular Cloning of a taxa-4 (20), 11(12) -dien-5α-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli [J]. Arch Biochem Biophys, 2000, 374:371 - 380.
  • 34
    • 4444236702 scopus 로고    scopus 로고
    • Regioselectivity of taxoid-O-acetyltransferases: Heterologous expression and characterization of a new taxadien-5α-ol-O-acetyltransferase [J]
    • Chau MD, Walker K, Long R, et al. Regioselectivity of taxoid-O-acetyltransferases: heterologous expression and characterization of a new taxadien-5α-ol-O-acetyltransferase [J]. Arch Biochem Biophy, 2004, 430:237 - 246.
    • (2004) Arch Biochem Biophy , vol.430 , pp. 237-246
    • Chau, M.D.1    Walker, K.2    Long, R.3
  • 35
    • 0035852639 scopus 로고    scopus 로고
    • Molecular cloning of a cytochrome P450 taxane 10β-hydroxylase cDNA from Taxus and functional expression in yeast [J]
    • Schoendorf A, Rithner CD, Williams RM, et al. Molecular cloning of a cytochrome P450 taxane 10β-hydroxylase cDNA from Taxus and functional expression in yeast [J]. Proc Natl Acad Sci USA, 2001, 98:1501 - 1506.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1501-1506
    • Schoendorf, A.1    Rithner, C.D.2    Williams, R.M.3
  • 36
    • 2642550828 scopus 로고    scopus 로고
    • Taxol biosynthesis; molecular cloning and characterization of a cytochrome P450 taxoid 7β-hydroxylase [J]
    • Chau MD, Jennewein S, Walker K, et al. Taxol biosynthesis; molecular cloning and characterization of a cytochrome P450 taxoid 7β-hydroxylase [J]. Chem Biol, 2004, 11:663 - 672.
    • (2004) Chem Biol , vol.11 , pp. 663-672
    • Chau, M.D.1    Jennewein, S.2    Walker, K.3
  • 37
    • 2642547256 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a cytochrome taxoid 2α-hydroxylase involved in Taxol biosynthesis [J]
    • Chau MD, Croteau R. Molecular cloning and characterization of a cytochrome taxoid 2α-hydroxylase involved in Taxol biosynthesis [J]. Arch Biochem Biophys, 2004, 427:48 - 57.
    • (2004) Arch Biochem Biophys , vol.427 , pp. 48-57
    • Chau, M.D.1    Croteau, R.2
  • 38
    • 0035923612 scopus 로고    scopus 로고
    • Taxol biosynthesis: Taxane 13α-hydroxylase is a cytochrome P450-dependent monooxygenase [J]
    • Jennewein S, Rithner CD, Williams RM, et al. Taxol biosynthesis: Taxane 13α-hydroxylase is a cytochrome P450-dependent monooxygenase [J]. Proc Natl Acad Sci USA, 2001, 98:13595 - 13600.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13595-13600
    • Jennewein, S.1    Rithner, C.D.2    Williams, R.M.3
  • 39
    • 0034610386 scopus 로고    scopus 로고
    • Taxol biosynthesis; molecular cloning of a benzoyl-CoA; taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli [J]
    • Walker K, Croteau R. Taxol biosynthesis; molecular cloning of a benzoyl-CoA; taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli [J]. Proc Natl Acad Sci USA, 2000, 97:13591 - 13596.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13591-13596
    • Walker, K.1    Croteau, R.2
  • 40
    • 0242669969 scopus 로고    scopus 로고
    • Taxoid metabolism; Taxoid 14/3-hydroxylase is a cytochrome P450-dependent monooxygenase [J]
    • Jennewein S, Rithner CD, Williams RM, et al. Taxoid metabolism; Taxoid 14/3-hydroxylase is a cytochrome P450-dependent monooxygenase [J]. Arch Biochem Biophys, 2003, 413:262 - 270.
    • (2003) Arch Biochem Biophys , vol.413 , pp. 262-270
    • Jennewein, S.1    Rithner, C.D.2    Williams, R.M.3
  • 41
    • 0036789932 scopus 로고    scopus 로고
    • Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in taxol biosynthesis [J]
    • Walker K, Fujisaki S, Long R, et al. Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in taxol biosynthesis [J]. Proc Natl Acad Sci USA, 2002, 99: 12715 - 12720.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12715-12720
    • Walker, K.1    Fujisaki, S.2    Long, R.3
  • 42
    • 0037047151 scopus 로고    scopus 로고
    • The final acylation step in taxol biosynthesis; cloning of the taxoid C13-side-ohain N-benzoyltransferase from Taxus [J]
    • Walker K, Long R, Croteau R. The final acylation step in taxol biosynthesis; cloning of the taxoid C13-side-ohain N-benzoyltransferase from Taxus [J]. Proc Natl Acad Sci USA, 2002, 99:9166 - 9171.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 9166-9171
    • Walker, K.1    Long, R.2    Croteau, R.3
  • 43
    • 0034681193 scopus 로고    scopus 로고
    • Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli [J]
    • Walker K, Croteau R. Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli [J]. Proc Natl Acad Sci USA, 2000, 97:583 - 587.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 583-587
    • Walker, K.1    Croteau, R.2
  • 45
    • 0034838359 scopus 로고    scopus 로고
    • Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol [J]
    • Huang QL, Roessner CA, Croteau R, et al. Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol [J]. Bioorg Med Chem, 2001, 9:2237 - 2242.
    • (2001) Bioorg Med Chem , vol.9 , pp. 2237-2242
    • Huang, Q.L.1    Roessner, C.A.2    Croteau, R.3
  • 46
    • 28444493024 scopus 로고    scopus 로고
    • Studies on combinatorial biosynthesis of taxadiene in Escherichia coli [J]
    • Wang W, Kong JQ, Meng C, et al. Studies on combinatorial biosynthesis of taxadiene in Escherichia coli [J]. Chin Pharm J, 2005, 40:1428 - 1431.
    • (2005) Chin Pharm J , vol.40 , pp. 1428-1431
    • Wang, W.1    Kong, J.Q.2    Meng, C.3
  • 47
    • 33746378650 scopus 로고    scopus 로고
    • Taxol biosynthesis and molecular genetics [J]
    • Croteau R, Ketchum REB, Long RM, et al. Taxol biosynthesis and molecular genetics [J]. Phytochem Rev, 2006, 5:75 - 97.
    • (2006) Phytochem Rev , vol.5 , pp. 75-97
    • Croteau, R.1    Ketchum, R.E.B.2    Long, R.M.3


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