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Volumn 17, Issue 3, 2007, Pages 331-337

Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

DJ 1 PROTEIN; PARKIN; PINK1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

EID: 34249937901     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.conb.2007.04.010     Document Type: Review
Times cited : (231)

References (54)
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    • 10.1093/hmg/ddm083. The authors demonstrate that mitochondria from parkin knockout mice and mice expressing mutant human SNCA exhibit defects in mitochondrial respiration. parkin mutant mice expressing SNCA also displayed age-dependent defects in mitochondrial morphology within dopaminergic neurons. These defects were also seen in mice either mutant for parkin or expressing SNCA more frequently than in wild type mice, but the number of damaged mitochondria only reached statistical significance in mice with both genetic modifications.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.