Extracellular disulfide exchange and the regulation of cellular function

Antioxidants and Redox Signaling

Volumn 8, Issue 3-4, 2006, Pages 312-324

  Jordan, Peter A ^a   Gibbins, Jonathan M ^a  

^a UNIVERSITY OF READING   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA1 INTEGRIN; BETA3 INTEGRIN; CD4 ANTIGEN; GLYCOPROTEIN GP 120; ISOMERASE; PROTEIN DISULFIDE ISOMERASE; PROTEIN ERP5; PROTEIN ERP57; PROTEIN ERP72; THIOL ISOMERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; BINDING AFFINITY; CELL ADHESION; CELL FUNCTION; CELL FUSION; CELL SECRETION; CELL SURFACE; COW; DISULFIDE BOND; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; REVIEW; VIRUS CELL INTERACTION;

ANIMALS; ANTIGENS, CD4; CELL ADHESION; CELL FUSION; CELL MEMBRANE; DISULFIDES; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; HUMANS; INTEGRINS; PROTEIN DISULFIDE-ISOMERASE; PROTEIN STRUCTURE, TERTIARY;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 33646698875     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2006.8.312     Document Type: Review

References (108)

1. Akagi S, Yamamoto A, Yoshimori T, Masaki R, Ogawa R, and Tashiro Y. Distribution of protein disulfide isomerase in rat hepatocytes. J Histochem Cytochem 36: 1533-1542, 1988.
2. Arnaout MA, Goodman SL, and Xiong JP. Coming to grips with integrin binding to ligands. Curr Opin Cell Biol 14: 641-651, 2002.
3. Asselin J, Gibbins JM, Achison M, Lee YH, Morton LF, Farndale RW, Barnes MJ, and Watson SP. A collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma2 in platelets independent of the integrin alpha2beta1. Blood 89: 1235-1242, 1997.
4. Baksh S, Burns K, Andrin C, and Michalak M. Interaction of calreticulin with protein disulfide isomerase. J Biol Chem 270: 31338-31344, 1995.
5. Basani RB, French DL, Vilaire G, Brown DL, Chen F, Coller BS, Derrick JM, Gartner TK, Bennett JS, and Poncz M. A naturally occurring mutation near the amino terminus of alphaIIb defines a new region involved in ligand binding to alphaIIbbeta3. Blood 95: 180-188, 2000.
6. Bennett JS, Chan C, Vilaire G, Mousa SA, and DeGrado WF. Agonist-activated alphav beta3 on platelets and lymphocytes binds to the matrix protein osteopontin. J Biol Chem 272: 8137-8140, 1997.
7. Bennett TA, Edwards BS, Sklar LA, and Rogelj S. Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes. J Immunol 164: 4120-4129, 2000.
8. Burgess JK, Hotchkiss KA, Suter C, Dudman NPB, Szollosi J, Chesterman CN, Chong BH, and Hogg PJ. Physical proximity and functional association of glycoprotein 1ba and protein disulfide isomerase on the platelet plasma membrane. J Biol Chem 275: 9758-9766, 2000.
9. Chen K, Detwiler TC, and Essex DW. Characterisation of protein, disulfide isomerase released from activated platelets. Br J Haematol 90: 425-431, 1995.
10. Chen K, Lin Y, and Detwiler TC. Protein disulfide isomerase activity is released by activated platelets. Blood 79: 2226-2228, 1992.
11. 2+ regulation of interactions between endoplasmic reticulum chaperones. J Biol Chem 274: 6203-6211, 1999.
12. Cumming RC, Andon NL, Haynes PA, Park M, Fischer WH, and Schubert D. Protein disulfide bond formation in the cytoplasm during oxidative stress. J Biol Chem 279: 21749-21758, 2004.
13. Davis G and Camarillo C. Regulation of integrin-mediated myeloid cell adhesion to fibronectin: influence of disulfide reducing agents, divalent cations and phorbol ester. J Immunol 151: 7138-7150, 1993.
14. Derrick JM, Loudon RG, and Gartner TK. Peptide LSAR-LAF activates alpha(IIb)beta3 on resting platelets and causes resting platelet aggregate formation without platelet shape change. Thromb Res 89: 31-40, 1998.
15. Derrick JM, Taylor DB, Loudon RG, and Gartner TK. The peptide LSARLAF causes platelet secretion and aggregation by directly activating the integrin alphaIIbbeta3. Biochem J 325 (Pt 2): 309-313, 1997.
16. Ding Z, Kimn S, Dorsam RT, Jin J, and Kunapuli SP. Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270. Blood 101: 3908-3914, 2003.
17. Dobson CM. The structural basis of protein folding and its links with human disease. Philos Trans R Soc Lond B Biol Sci 356: 133-145, 2001.
18. Donella-Deana A, James P, Staudenmann W, Cesaro L, Marin O, Brunati AM, Ruzzene M, and Pinna LA. Isolation from spleen of a 57-kDa protein substrate of the tyrosine kinase Lyn. Identification as a protein related to protein disulfide-isomerase and localisation of the phosphorylation sites. Eur J Biochem 235: 18-25, 1996.
19. Donoghue N, Yam PTW, Jiang X-M, and Hogg PJ. Presence of closely spaced protein thiols on the surface of mammalian cells. Protein Sci 9: 2436-2445, 2000.
20. Eckert DM and Kim PS. Mechanisms of viral membrane fusion and its inhibition. Annu Rev Biochem 70: 777-810, 2001.
21. Essex DW. The role of thiols and disulfides in platelet function. Antioxid Redox Signal 6: 736-746, 2004.
22. Essex DW, Chen K, and Swiatkowska M. Localisation of protein disulfide isomerase to the external surface of the platelet plasma membrane. Blood 86: 2168-2173, 1995.
23. Essex DW and Li M. Protein disulfide isomerase mediates platelet aggregation and secretion. Br J Haematology 104: 448-454, 1999.
24. Essex DW and Li M. Redox control of platelet aggregation. Biochemistry 42: 129-136, 2003.
25. Essex DW, Li M, Feinman RD, and Miller A. Platelet surface glutathione reductase-like activity. Blood 104: 1383-1385, 2004.
26. Essex DW, Li M, Miller A, and Feinman RD. Protien disulfide isomerase and sulfhydryl-dependent pathways in platelet activation. Biochemistry 40: 6070-6075, 2001.
27. Farquhar R, Honey N, Murant SJ, Bossier P, Schultz L, Montgomery D, Ellis RW, Freedman RB, and Tuite MF. Protein disulfide isomerase is essential for viability in Saccharomyces cerevisiae. Gene 108: 81-89, 1991.
28. Ferrari DM, Nguyen Van P, Kratzin HD, and Soling HD. ERp28, a human endoplasmic-reticulum-lumenal protein, is a member of the protein disulfide isomerase family but lacks a CXXC thioredoxin-box motif. Eur J Biochem 255: 570-579, 1998.
29. Ferrari DM and Soling H-D. The protein disulfide isomerase family: Unraveling a string of folds. Biochem J 339: 1-10, 1999.
30. Furie B, Furie BC, and Flaumenhaft R. A journey with platelet P-selectin: the molecular basis of granule secretion, signalling and cell adhesion. Thromb Haemost 86: 214-221, 2001.
31. Gallina A, Hanley TM, Mandel R, Trahey M, Broder CC, Viglianti GA, and Ryser HJ. Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry. J Biol Chem 277: 50579-50588, 2002.
32. Gilbert HF. Molecular and cellular aspects of thiol-disulfide exchange. Adv Enzymol Relat Areas Mol Biol 63: 69-172, 1990.
33. Hartl FU and Hayer-Hartl M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295: 1852-1858, 2002.
34. Hawkins HC, Blackburn EC, and Freedman RB. Comparison of the activities of protein disulfide-isomerase and thioredoxin in catalysing disulfide isomerization in a protein substrate. Biochem J 275 (Pt 2): 349-353, 1991.
35. Hayano T and Kikuchi M. Cloning and sequencing of the cDNA encoding human P5. Gene 164: 377-378, 1995.
36. Hogg PJ. Disulfide bonds as switches for protein function. Trends Biochem Sci 28: 210-214, 2003.
37. Hotchkiss KA, Chesterman CN, and Hogg PJ. Catalysis of disulfide isomerization in thrombospondin 1 by protein disulfide isomerase. Biochemistry 35: 9761-9767, 1996.
38. Hotchkiss KA, Matthias LJ, and Hogg PJ. Exposure of the cryptic Arg-Gly-Asp sequence in thrombospondin-1 by protein disulfide isomerase. Biochim Biophys Acta 1388: 478-488, 1998.
39. Hughes RC. Secretion of the galectin family of mammalian carbohydrate-binding proteins. Biochim Biophys Acta 1473: 172-185, 1999.
40. Jang JH and Hanash S. Profiling of the cell surface proteome. Proteomics 3: 1947-1954, 2003.
41. Janson IM, Ek B, and Ek P. Phosphorylation of CaBP1 and CaBP2 by protein kinase CK2. J Biochem (Tokyo) 121: 112-117, 1997.
42. Janson IM, Tomik R, O'Farrell F, and Elk P. KDEL motif interacts with a specific sequence in mammalian erd2 receptor. Biochem Biophys. Res Comm 247: 447-451, 1998.
43. Jiang X-M, Fitzgerald M, Grant CM, and Hogg PJ. Redox control of exofacial protein thiols/disulfides by protein disuflide isomerase. J Biol Chem 274: 2416-2423, 1999.
44. Jordan PA, Stevens JM, Hubbard GP, Barrett NE, Sage T, Authi KS, and Gibbins JM. A role for the thiol isomerase protein ERp5 in platelet function. Blood 105: 1500-1507, 2005.
45. Kemmink J, Darby NJ, Dijkstra K, Nilges M, and Creighton TE. The folding catalyst protein disulfide isomerase is constructed of active and inactive thioredoxin modules. Curr Biol 7: 239-245, 1997.
46. Kikuchi M, Doi E, Tsujimoto I, Horibe T and Tsujimoto Y. Functional analysis of human P5, a protein disulfide isomerase homologue. J Biochem (Tokyo) 132: 451-455, 2002.
47. Knight CG, Morton LF, Peachey AR, Tuckwell DS, Farndale RW, and Barnes MJ. The collagen-binding A-domains of integrins alpha(1)beta(1) and alpha(2)beta(1) recognize the same specific amino acid sequence, GFOGER, in native (triple-helical) collagens. J Biol Chem 275: 35-40, 2000.
48. Koivu J, Myllyla R, Helaakoski T, Pihlajaniemi T, Tasanen K, and Kivirikko KI. A single polypeptide acts both as the beta subunit of prolyl 4-hydroxylase and as a protein disulfide-isomerase. J Biol Chem 262: 6447-6449, 1987.
49. Kramer B, Ferrari DM, Klappa P, Pohlmann N, and Soling H-D. Functional roles and efficiencies of the thioredoxin boxes of calcium-binding proteins 1 and 2 in protein folding. Biochem J 357: 83-95, 2001.
50. Kroning H, Kahne T, Ittenson A, Franke A, and Ansorge S. Thiol-proteindisulfide-oxidoreductase (protein disulfide isomerase): A new plasma membrane constituent of mature human B lymphocytes. Scand J immunol 39: 346-350, 1994.
51. Lahav J, Gofer-Dadosh N, Luboshitz J, Hess O, and Shaklai M. Protein disulfide isomerase mediates, integrin-dependent adhesion. FEBS Lett 475: 89-92, 2000.
52. Lahav J, Jurk K, Hess O, Barnes MJ, Farndale RW, Luboshitz J, and Kehrel BE. Sustained integrin ligation involves extracellular free sulfhdryls and enzymatically catalyzed disulfide exchange. Blood 100: 2472-2478, 2002.
53. 1. Blood 102: 2085-2092, 2003.
54. LaMantia ML and Lennarz WJ. The essential function of yeast protein disulfide isomerase does not reside in its isomerase activity. Cell 74: 899-908, 1993.
55. Langenbach KJ and Sottile J. Identification of protein-disulfide isomerase activity in fibronectin. J Biol Chem 274: 7032-7038, 1999.
56. Liddington RC and Ginsberg MH. Integrin activation takes shape. J Cell Biol 158: 833-839, 2002.
57. Locker JK and Griffiths G. An unconventional role for cytoplasmic disulfide bonds in vaccinia virus proteins. J Cell Biol 144: 267-279, 1999.
58. Luz JM, Markus H, Farquhar R, Schultz LD, Ellis RW, Freedman RB, and Tuite MF. Expression and secretion of human protein disulfide isomerase in Saccharomyces cerevisiae. Biochem Soc Trans 22: 76S, 1994.
59. MacIntyre DE and Gordon JL. Evidence for two populations of disulfide bonds on blood platelets. Biochem Soc Trans 2: 873-875, 1974.
60. MacIntyre DE and Gordon JL. Prostaglandin receptor on blood platelets: effects of thiol reagents on inhibition of platelet aggregation by prostaglandin E1. Biochem Soc Trans 2: 1265-1269, 1974.
61. MacIntyre DE, Grainge CA, Drummond AH, and Gordon JL. Effect of thiol reagents on platelet transport processes and responses to stimuli. Biochem Pharmacol 26: 319-323, 1977.
62. Mandel R, Ryser HJ-P, Ghani F, Wu M, and Peak D. Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide isomerase. Proc Natl Acad Sci USA 90: 4112-4116, 1993.
63. Markovic I, Pulyaeva H, Sokoloff A, and Chernomordik LV. Membrane fusion mediated by baculovirus gp64 involves assembly of stable gp64 trimers into multiprotein aggregates. J Cell Biol 143: 1155-1166, 1998.
64. Markovic I, Stantchev TS, Fields KH, Tiffany LJ, Tomiç M, Weiss CD, Broder CC, Strebel K, and Clouse KA. Thiol/disulfide exchange is a prerequisite for CXCR4-tropic HIV-1 envelope-mediated T-cell fusion during viral entry. Blood 103: 1586-1594, 2004.
65. Martire G, Mottola G, Pascale MC, Malagolini N, Turrini I, Serafini-Cessi F, Jackson MR, and Bonatti S. Different fate of a single reported protein containing KDEL or KDXX targeting signals stably expressed in mammalian cells. J Biol Chem 271: 3541-3547, 1996.
66. Matthias LJ and Hogg PJ. Redox control on the cell surface: Implications for HIV-1 entry. Antioxid Redox Signal 5: 133-138, 2003.
67. Matthias LJ, Yam PT, Jiang XM, Vandegraaff N, Li P, Poumbourios P, Donoghue N, and Hogg PJ. Disulfide exchange in domain 2 of CD4 is required for entry of HIV-1. Nat Immunol 3: 727-732, 2002.
68. Mazzarella RA, Srinivasan M, Haugejorden SM, and Green M. ERp72, an abundant luminal endoplasmic reticulum protein, contains three copies of the active site sequences of protein disulfide isomerase. J Biol Chem 265: 1094-1101, 1990.
69. Megidish T, Takio K, Titani K, Iwabuchi K, Hamaguchi A, Igarashi Y, and Hakomori S. Endogenous substrates of sphingosine-dependent kinases (SDKs) are chaperone proteins: heat shock proteins, glucose-regulated proteins, protein disulfide isomerase, and calreticulin. Biochemistry 38: 3369-3378, 1999.
70. Milev Y and Essex DW. Protein disulfide isomerase catalyzes the formation of disulfide-linked complexes of thrombospondin-1 with thrombin-antithrombin III. Arch Biochem Biophys 361: 120-126, 1999.
71. Nieswandt B and Watson SP. Platelet-collagen interaction: is GP VI the central receptor? Blood 102: 449-461, 2003.
72. Norgaard P, Westphal V, Tachibana C, Alsoe L, Holst B, and Winther JR. Functional differences in yeast protein disulfide isomerases. J Cell Biol 152: 553-562, 2001.
73. 3 has an endogenous thiol isomerase activity. J Biol Chem 275: 36984-36990, 2000.
74. Palabrica T, Lobb R, Furie BC, Aronovitz M, Benjamin C, Hsu YM, Sajer SA, and Furie B. Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets. Nature 359: 848-851, 1992.
75. Pelham HR. Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment. EMBO J 7: 913-918, 1988.
76. Phillips DR, Charo IF, and Scarborough RM. GPIIb-IIIa: The responsive integrin. Cell 359-362, 1991.
77. Ren Z, Riley NJ, Needleman LA, Sanders JM, Swanson GT, and Marshall J. Cell surface expression of GluR5 kainate receptors is regulated by an endoplasmic reticulum retention signal. J Biol Chem 278: 52700-52709, 2003.
78. Ruggeri ZM. Von Willebrand factor, platelets and endothelial cell interactions. J Thromb Haemost 1: 1335-1342, 2003.
79. Ruiz C, Liu C-Y, Sun Q-H, Sigaud-Fiks M, Fressinaud E, Muller J-Y, Nurden P, Nurden AT, Newman PJ, and Valentin N. A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (IIb3) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype. Blood 98: 2432-2441, 2001.
80. Ryser HJ, Levy EM, Mandel R, and DiSciullo GJ. Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction. Proc Natl Acad Sci USA 91: 4559-4563, 1994.
81. Sauk JJ, Norris K, Herbert C, Ordonez J, and Reynolds M. Hsp47 binds to the KDEL receptor and cell surface expression is modulated by cytoplasmic and endosomal pH. Connect Tiss Res 37: 105-119, 1998.
82. Shattil SJ, Kashiwagi H, and Pampori N. Integrin signaling: the platelet paradigm. Blood 91: 2645-2657, 1998.
83. Shattil SJ and Newman PJ. Integrins: dynamic scaffolds for adhesion and signaling in platelets. Blood 104: 1606-1615, 2004.
84. Shin BK, Wang H, Yim AM, Naour FL, Brichory F, Jang JH, Zhao R, Puravs E, Tra J, Michael CW, Misek DE, and Hanash SM. Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function. J Biol Chem 278: 7607-7616, 2003.
85. Sun QH, Liu CY, Wang R, Paddock C, and Newman PJ. Disruption of the long-range GPIIIa Cys(5)-Cys(435) disulfide bond results in the production of constitutively active GPIIb-IIIa (alpha(IIb)beta(3)) integrin complexes. Blood 100: 2094-2101, 2002.
86. Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, de Pereda JM, Ginsberg MH, and Calderwood DA. Talin binding to integrin beta tails: a final common step in integrin activation. Science 302: 103-106, 2003.
87. Tager M, Kroning H, Thiel U, and Ansorge S. Membrane-bound protein disulfide isomerase(PDI) is involved in regulation of surface expression of thiols and drug sensitivity of B-CLL cells. Exp Hematol 25: 601-607, 1997.
88. Tanudji M, Hevi S, and Chuck SL. Improperly folded green fluorescent protein is secreted via a non-classical pathway. J Cell Sci 115: 3849-3857, 2002.
89. Teasdale RD and Jackson MR. Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the golgi apparatus. Annu Rev Cell Dev Biol 12: 27-54, 1996.
90. Tedder TF, Steeber DA, Chen A, and Engel P. The selectins: vascular adhesion molecules. FASEB J 9: 866-873, 1995.
91. Terada K, Manchikalapudi P, Noiva R, Jauregui HO, Stocken RJ, and Schilsky ML. Secretion, surface localisation, turnover, and steady state expression of protein disulfide isomerase in rat hepatocytes. J Biol Chem 270: 20410-20416, 1995.
92. Triantafilou M and Triantafilou K. Heat-shock protein 70 and heat-shock protein 90 associate with Toll-like receptor 4 in response to bacterial lipopolysaccharide. Biochem Soc Trans 32: 636-639, 2004.
93. Turano C, Coppari S, Altieri F, and Ferraro A. Proteins of the PDI family: unpredicted non-ER locations and functions. J Cell Physiol 193: 154-163, 2002.
94. Vabulas RM, Ahmad-Nejad P, Ghose S, Kirschning CJ, Issels RD, and Wagner H. HSP70 as endogenous stimulus of the toll/interleukin-1 receptor signal pathway. J Biol Chemin: 15107-15112, 2002.
95. Vabulas RM, Braedel S, Hilf N, Singh-Jasuja H, Herter S, Ahmad-Nejad P, Kirschning CJ, Costa Cd, Rammensee H-G, Wagner H, and Schild H. The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway. J Biol Chem 111: 20847-20853, 2002.
96. Wagner CL, Mascelli MA, Neblock DS, Weisman HF, Coller BS, and Jordan RE. Analysis of GPIIb/IIIa receptor number by quantification of 7E3 binding to human platelets. Blood 88: 907-914, 1996.
97. Walsh GM, Sheehan D, Kinsella A, Moran N, and O'Neill S. Redox modulation of integrin alpha IIb beta 3 involves a novel allosteric regulation of its thiol isomerase activity. Biochemistry 43: 473-480, 2004.
98. Wang R, Peterson J, Aster RH, and Newman PJ. Disruption of a long-range disulfide bond between residues Cys406 and Cys655 in glycoprotein Ilia does not affect the function of platelet glycoprotein IIb-IIIa. Blood 90: 1718-1719, 1997.
99. Wetterau JR, Combs KA, Spinner SN, and Joiner BJ. Protein disulfide isomerase is a component of the microsomal triglyceride transfer protein complex. J Biol Chem 265: 9801-9807, 1990.
100. Wilkinson B and Gilbert HF. Protein disulfide isomerase. Biochim Biophys Acta 1699: 35-44, 2004.
101. Xie LJ, Chesterman CN, and Hogg PJ. Reduction of von Willebrand factor by endothelial cells. Thromb Haemost 84: 506-513, 2000.
102. Xie LJ, Chesterman CN, and Hogg PJ. Control of von Willebrand factor multimer size by thrombospondin-1. J Exp Med 193: 1341-1349, 2001.
103. Xiong JP, Stehle T, Diefenbach B, Zhang R, Dunker R, Scott DL, Joachimiak A, Goodman SL, and Arnaout MA. Crystal structure of the extracellular segment of integrin alpha Vbeta3. Science 294: 339-345, 2001.
104. Xiong JP, Stehle T, Goodman SL, and Arnaout MA. New insights into the structural basis of integrin activation. Blood 102: 1155-1159, 2003.
105. 3. J Biol Chem 275: 7249-7260, 2000.
106. Yan B and Smith JW. A redox site involved in integrin activation. J Biol Chem 275: 39964-39972, 2000.
107. Yan B and Smith JW. Mechanism of integrin activation by disulfide bond reduction. Biochemistry 40: 8861-8867, 2001.
108. Zai A, Rudd A, Scribner AW, and Loscalzo J. Cell-surface protein disulfide isomerase catalyses transnitrosation and regulates intracellular transfer of nitric oxide. J Clin Invest 103: 393-399, 1999.