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Volumn 60, Issue 3, 2003, Pages 629-638

CD4+ T cell-mediated immunity against prion proteins

Author keywords

MHC class II; Prion protein; T lymphocyte

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PRION PROTEIN; RECOMBINANT PROTEIN;

EID: 0345373985     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000180300054     Document Type: Article
Times cited : (11)

References (57)
  • 2
    • 0001907961 scopus 로고
    • La tremblante du mouton est bien inoculane
    • Cuille, J. et al. (1938) La tremblante du mouton est bien inoculane. C. R. Acad. Sci. Paris 206: 78-79
    • (1938) C. R. Acad. Sci. Paris , vol.206 , pp. 78-79
    • Cuille, J.1
  • 3
    • 0014211846 scopus 로고
    • Does the agent of scrapie replicate without nucleic acid?
    • Alper T., Cramp W. A., Haig D. A. and Clarke M. C. (1967) Does the agent of scrapie replicate without nucleic acid? Nature 214: 764-766
    • (1967) Nature , vol.214 , pp. 764-766
    • Alper, T.1    Cramp, W.A.2    Haig, D.A.3    Clarke, M.C.4
  • 4
    • 0014190760 scopus 로고
    • Self-replication and scrapie
    • Griffith J. S. (1967) Self-replication and scrapie. Nature 215: 1043-1044
    • (1967) Nature , vol.215 , pp. 1043-1044
    • Griffith, J.S.1
  • 6
    • 0022476747 scopus 로고
    • Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
    • Basler K., Oesch B., Scott M., Westaway D., Walchli M., Groth D. F. et al. (1986) Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell 46: 417-428
    • (1986) Cell , vol.46 , pp. 417-428
    • Basler, K.1    Oesch, B.2    Scott, M.3    Westaway, D.4    Walchli, M.5    Groth, D.F.6
  • 8
    • 0026567814 scopus 로고
    • Nearly ubiquitous tissue distribution of the scrapie agent precursor protein
    • Bendheim P. E., Brown H. R., Rudelli R. D., Scala L. J., Goller N. L., Wen G. Y. et al. (1992) Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology 42: 149-156
    • (1992) Neurology , vol.42 , pp. 149-156
    • Bendheim, P.E.1    Brown, H.R.2    Rudelli, R.D.3    Scala, L.J.4    Goller, N.L.5    Wen, G.Y.6
  • 9
    • 0027534612 scopus 로고
    • Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing
    • Stahl N., Baldwin M. A., Teplow D. B., Hood L., Gibson B. W., Burlingame A. L. et al. (1993) Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry 32: 1991-2002
    • (1993) Biochemistry , vol.32 , pp. 1991-2002
    • Stahl, N.1    Baldwin, M.A.2    Teplow, D.B.3    Hood, L.4    Gibson, B.W.5    Burlingame, A.L.6
  • 10
    • 0030836511 scopus 로고    scopus 로고
    • NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231)
    • Riek R., Hornemann S., Wider G., Glockshuber R. and Wüthrich K. (1997) NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231). FEBS Lett. 413: 282-288
    • (1997) FEBS Lett. , vol.413 , pp. 282-288
    • Riek, R.1    Hornemann, S.2    Wider, G.3    Glockshuber, R.4    Wüthrich, K.5
  • 11
    • 0025944507 scopus 로고
    • Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy
    • Caughey B. W., Dong A., Bhat K. S., Ernst D., Hayes S. F. and Caughey W. S. (1991) Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy. Biochemistry 30: 7672-7680
    • (1991) Biochemistry , vol.30 , pp. 7672-7680
    • Caughey, B.W.1    Dong, A.2    Bhat, K.S.3    Ernst, D.4    Hayes, S.F.5    Caughey, W.S.6
  • 12
    • 0027332116 scopus 로고
    • Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins
    • Pan K. M., Baldwin M., Nguyen J., Gasset M., Serban A., Groth D. et al. (1993) Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc. Natl. Acad. Sci. USA 90: 10962-10966
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10962-10966
    • Pan, K.M.1    Baldwin, M.2    Nguyen, J.3    Gasset, M.4    Serban, A.5    Groth, D.6
  • 13
    • 0032923522 scopus 로고    scopus 로고
    • Molecular genetics of transmissible spongiform encephalopathies
    • Weissmann C. (1999) Molecular genetics of transmissible spongiform encephalopathies. J. Biol. Chem. 274: 3-6
    • (1999) J. Biol. Chem. , vol.274 , pp. 3-6
    • Weissmann, C.1
  • 14
    • 0031859927 scopus 로고    scopus 로고
    • The prion diseases
    • Prusiner S. B. (1998) The prion diseases. Brain Pathol. 8: 499-513
    • (1998) Brain Pathol. , vol.8 , pp. 499-513
    • Prusiner, S.B.1
  • 17
    • 0029863648 scopus 로고    scopus 로고
    • Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie
    • Fischer M., Rulicke T., Raeber A., Sailer A., Moser M., Oesch B. et al. (1996) Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J. 15: 1255-1264
    • (1996) EMBO J. , vol.15 , pp. 1255-1264
    • Fischer, M.1    Rulicke, T.2    Raeber, A.3    Sailer, A.4    Moser, M.5    Oesch, B.6
  • 18
    • 0024820814 scopus 로고
    • Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
    • Scott M., Foster D., Mirenda C., Serban D., Coufal F., Walchli M. et al. (1989) Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques. Cell 59: 847-857
    • (1989) Cell , vol.59 , pp. 847-857
    • Scott, M.1    Foster, D.2    Mirenda, C.3    Serban, D.4    Coufal, F.5    Walchli, M.6
  • 19
    • 0028822204 scopus 로고
    • A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells
    • Priola S. A. and Chesebro B. (1995) A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells. J. Virol. 69: 7754-7758
    • (1995) J. Virol. , vol.69 , pp. 7754-7758
    • Priola, S.A.1    Chesebro, B.2
  • 20
    • 0344326239 scopus 로고    scopus 로고
    • Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein
    • Wopfner F., Weidenhofer G., Schneider R., Brunn A. von, Gilch S., Schwarz T. F. et al. (1999) Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein. J. Mol. Biol. 289: 1163-1178
    • (1999) J. Mol. Biol. , vol.289 , pp. 1163-1178
    • Wopfner, F.1    Weidenhofer, G.2    Schneider, R.3    Von Brunn, A.4    Gilch, S.5    Schwarz, T.F.6
  • 21
    • 0032560124 scopus 로고    scopus 로고
    • Scrapie infectivity found in resistant species
    • Race R. and Chesebro B. (1998) Scrapie infectivity found in resistant species. Nature 392: 770
    • (1998) Nature , vol.392 , pp. 770
    • Race, R.1    Chesebro, B.2
  • 23
    • 0034790796 scopus 로고    scopus 로고
    • Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: Analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans
    • Race R., Raines A., Raymond G. J., Caughey B. and Chesebro B. (2001) Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans. J. Virol. 75: 10106-10112
    • (2001) J. Virol. , vol.75 , pp. 10106-10112
    • Race, R.1    Raines, A.2    Raymond, G.J.3    Caughey, B.4    Chesebro, B.5
  • 24
    • 0036168776 scopus 로고    scopus 로고
    • Chronic subclinical prion disease induced by low-dose inoculum
    • Thackray A. M., Klein M. A., Aguzzi A. and Bujdoso R. (2002) Chronic subclinical prion disease induced by low-dose inoculum. J. Virol. 76: 2510-2517
    • (2002) J. Virol. , vol.76 , pp. 2510-2517
    • Thackray, A.M.1    Klein, M.A.2    Aguzzi, A.3    Bujdoso, R.4
  • 25
    • 0019508185 scopus 로고
    • Evidence for normal cell-mediated immunity in scrapie-infected mice
    • Kingsbury D. T., Smeltzer D. A., Gibbs C. J. and Gajdusek D. C. (1981) Evidence for normal cell-mediated immunity in scrapie-infected mice. Infect. Immun. 32: 1176-1180
    • (1981) Infect. Immun. , vol.32 , pp. 1176-1180
    • Kingsbury, D.T.1    Smeltzer, D.A.2    Gibbs, C.J.3    Gajdusek, D.C.4
  • 26
    • 0015843553 scopus 로고
    • Failure to demonstrate a humoral immune response to scrapie infection in mice
    • Porter D. D., Porter H. G. and Cox N. A. (1973) Failure to demonstrate a humoral immune response to scrapie infection in mice. J. Immunol. 111: 1407-1410
    • (1973) J. Immunol. , vol.111 , pp. 1407-1410
    • Porter, D.D.1    Porter, H.G.2    Cox, N.A.3
  • 27
    • 0020490156 scopus 로고
    • Identification of a protein that purifies with the scrapie prion
    • Bolton D. C., McKinley M. P. and Prusiner S. B. (1982) Identification of a protein that purifies with the scrapie prion. Science 218: 1309-1311
    • (1982) Science , vol.218 , pp. 1309-1311
    • Bolton, D.C.1    McKinley, M.P.2    Prusiner, S.B.3
  • 28
    • 0021884354 scopus 로고
    • Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain
    • Chesebro B., Race R., Wehrly K., Nishio J., Bloom M., Lechner D. et al. (1985) Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain. Nature 315: 331-333
    • (1985) Nature , vol.315 , pp. 331-333
    • Chesebro, B.1    Race, R.2    Wehrly, K.3    Nishio, J.4    Bloom, M.5    Lechner, D.6
  • 30
    • 0034798246 scopus 로고    scopus 로고
    • Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
    • Aucouturier P., Geissmann F., Damotte D., Saborio G. P., Meeker H. C., Kascsak R. et al. (2001) Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J. Clin. Invest 108: 703-708
    • (2001) J. Clin. Invest. , vol.108 , pp. 703-708
    • Aucouturier, P.1    Geissmann, F.2    Damotte, D.3    Saborio, G.P.4    Meeker, H.C.5    Kascsak, R.6
  • 32
    • 0032746253 scopus 로고    scopus 로고
    • Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells
    • Brown K. L., Stewart K., Ritchie D. L., Mabbott N. A., Williams A., Fraser H. et al. (1999) Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells. Nat. Med. 5: 1308-1312
    • (1999) Nat. Med. , vol.5 , pp. 1308-1312
    • Brown, K.L.1    Stewart, K.2    Ritchie, D.L.3    Mabbott, N.A.4    Williams, A.5    Fraser, H.6
  • 33
  • 34
    • 0026600865 scopus 로고
    • Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
    • Büeler H., Fischer M., Lang Y., Bluethmann H., Lipp H. P., DeArmond S. J. et al. (1992) Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356: 577-582
    • (1992) Nature , vol.356 , pp. 577-582
    • Büeler, H.1    Fischer, M.2    Lang, Y.3    Bluethmann, H.4    Lipp, H.P.5    DeArmond, S.J.6
  • 35
    • 0029825830 scopus 로고    scopus 로고
    • Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system
    • Brandner S., Raeber A., Sailer A., Blattler T., Fischer M., Weissmann C. et al. (1996) Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system. Proc. Natl. Acad. Sci. USA 93: 13148-13151
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13148-13151
    • Brandner, S.1    Raeber, A.2    Sailer, A.3    Blattler, T.4    Fischer, M.5    Weissmann, C.6
  • 36
    • 0034127890 scopus 로고    scopus 로고
    • High yield purification and physicochemical properties of full-length recombinant allelic variants of sheep prion protein linked to scrapie susceptibility
    • Rezaei H., Marc D., Choiset Y., Takahashi M., Hui Bon H. G., Haertle T. et al. (2000) High yield purification and physicochemical properties of full-length recombinant allelic variants of sheep prion protein linked to scrapie susceptibility. Eur. J. Biochem 267: 2833-2839
    • (2000) Eur. J. Biochem. , vol.267 , pp. 2833-2839
    • Rezaei, H.1    Marc, D.2    Choiset, Y.3    Takahashi, M.4    Hui Bon, H.G.5    Haertle, T.6
  • 37
    • 0030810150 scopus 로고    scopus 로고
    • Human prion proteins expressed in Escherichia coli and purified by high-affinity column refolding
    • Zahn R., Schroetter C. von and Wuthrich K. (1997) Human prion proteins expressed in Escherichia coli and purified by high-affinity column refolding. FEBS Lett. 417: 400-404
    • (1997) FEBS Lett. , vol.417 , pp. 400-404
    • Zahn, R.1    Von Schroetter, C.2    Wuthrich, K.3
  • 38
    • 0031771008 scopus 로고    scopus 로고
    • Generation of the vesicular stomatitis virus nucleoprotein cytotoxic T lymphocyte epitope requires proteasome-dependent and -independent proteolytic activities
    • Stoltze L., Dick T. P., Deeg M., Pommerl B., Rammensee H. G. and Schild H. (1998) Generation of the vesicular stomatitis virus nucleoprotein cytotoxic T lymphocyte epitope requires proteasome-dependent and -independent proteolytic activities. Eur. J. Immunol. 28: 4029-4036
    • (1998) Eur. J. Immunol. , vol.28 , pp. 4029-4036
    • Stoltze, L.1    Dick, T.P.2    Deeg, M.3    Pommerl, B.4    Rammensee, H.G.5    Schild, H.6
  • 39
    • 0033616564 scopus 로고    scopus 로고
    • Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication
    • Raeber A. J., Sailer A., Hegyi I., Klein M. A., Rulicke T., Fischer M. et al. (1999) Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication. Proc. Natl. Acad. Sci. USA 96: 3987-3992
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3987-3992
    • Raeber, A.J.1    Sailer, A.2    Hegyi, I.3    Klein, M.A.4    Rulicke, T.5    Fischer, M.6
  • 40
    • 0028011845 scopus 로고
    • Origin, structure and motifs of naturally processed MHC class II ligands
    • Rötzschke O. and Falk K. (1994) Origin, structure and motifs of naturally processed MHC class II ligands. Curr. Opin. Immunol. 6: 45-51
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 45-51
    • Rötzschke, O.1    Falk, K.2
  • 41
    • 0020690737 scopus 로고
    • Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes
    • Mathis D. J., Benoist C., Williams V. E., Kanter M. and McDevitt H. O. (1983) Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes. Proc. Natl. Acad. Sci. USA 80: 273-277
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 273-277
    • Mathis, D.J.1    Benoist, C.2    Williams, V.E.3    Kanter, M.4    McDevitt, H.O.5
  • 42
    • 0034856996 scopus 로고    scopus 로고
    • Modulation of proteinase-K resistant prion protein by prion peptide immunization
    • Souan L., Tal Y., Felling Y., Cohen I. R., Taraboulos A. and Mor F. (2001) Modulation of proteinase-K resistant prion protein by prion peptide immunization. Eur. J. Immunol. 31: 2338-2346
    • (2001) Eur. J. Immunol. , vol.31 , pp. 2338-2346
    • Souan, L.1    Tal, Y.2    Felling, Y.3    Cohen, I.R.4    Taraboulos, A.5    Mor, F.6
  • 44
    • 0033451935 scopus 로고    scopus 로고
    • Mechanisms and consequences of peptide selection by the I-Ak class II molecule
    • Latek R. R. and Unanue E. R. (1999) Mechanisms and consequences of peptide selection by the I-Ak class II molecule. Immunol. Rev. 172: 209-228
    • (1999) Immunol. Rev. , vol.172 , pp. 209-228
    • Latek, R.R.1    Unanue, E.R.2
  • 45
    • 0033696962 scopus 로고    scopus 로고
    • Control of antigen presentation by a single protease cleavage site
    • Antoniou A. N., Blackwood S. L., Mazzeo D. and Watts C. (2000) Control of antigen presentation by a single protease cleavage site. Immunity 12: 391-398
    • (2000) Immunity , vol.12 , pp. 391-398
    • Antoniou, A.N.1    Blackwood, S.L.2    Mazzeo, D.3    Watts, C.4
  • 46
    • 0028064707 scopus 로고
    • Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell
    • Nelson C. A., Petzold S. J. and Unanue E. R. (1994) Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell. Nature 371: 250-252
    • (1994) Nature , vol.371 , pp. 250-252
    • Nelson, C.A.1    Petzold, S.J.2    Unanue, E.R.3
  • 47
    • 0027261286 scopus 로고
    • Studies on a species-specific epitope in murine, ovine and bovine prion protein
    • Groschup M. H. and Pfaff E. (1993) Studies on a species-specific epitope in murine, ovine and bovine prion protein. J. Gen. Virol. 74: 1451-1456
    • (1993) J. Gen. Virol. , vol.74 , pp. 1451-1456
    • Groschup, M.H.1    Pfaff, E.2
  • 48
    • 0027491308 scopus 로고
    • Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies
    • Prusiner S. B., Groth D., Serban A., Koehler R., Foster D., Torchia M. et al. (1993) Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proc. Natl. Acad. Sci. USA 90: 10608-10612
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10608-10612
    • Prusiner, S.B.1    Groth, D.2    Serban, A.3    Koehler, R.4    Foster, D.5    Torchia, M.6
  • 49
    • 0030449597 scopus 로고    scopus 로고
    • Generation of monoclonal antibodies against human prion proteins in PrP0/0 mice
    • Krasemann S., Groschup M. H., Harmeyer S., Hunsmann G. and Bodemer W. (1996) Generation of monoclonal antibodies against human prion proteins in PrP0/0 mice. Mol. Med. 2: 725-734
    • (1996) Mol. Med. , vol.2 , pp. 725-734
    • Krasemann, S.1    Groschup, M.H.2    Harmeyer, S.3    Hunsmann, G.4    Bodemer, W.5
  • 50
    • 13144256747 scopus 로고    scopus 로고
    • Prion protein expression in different species: Analysis with a panel of new mAbs
    • Zanusso G., Liu D., Ferrari S., Hegyi I., Yin X., Aguzzi A. et al. (1998) Prion protein expression in different species: analysis with a panel of new mAbs. Proc. Natl. Acad. Sci. USA 95: 8812-8816
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8812-8816
    • Zanusso, G.1    Liu, D.2    Ferrari, S.3    Hegyi, I.4    Yin, X.5    Aguzzi, A.6
  • 51
    • 0035899413 scopus 로고    scopus 로고
    • Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
    • Peretz D., Williamson R. A., Kaneko K., Vergara J., Leclerc E., Schmitt-Ulms G. et al. (2001) Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature 412: 739-743
    • (2001) Nature , vol.412 , pp. 739-743
    • Peretz, D.1    Williamson, R.A.2    Kaneko, K.3    Vergara, J.4    Leclerc, E.5    Schmitt-Ulms, G.6
  • 52
    • 0035979274 scopus 로고    scopus 로고
    • Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
    • Enari M., Flechsig E. and Weissmann C. (2001) Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc. Natl. Acad. Sci. USA 98: 9295-9299
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9295-9299
    • Enari, M.1    Flechsig, E.2    Weissmann, C.3
  • 53
    • 0035812752 scopus 로고    scopus 로고
    • Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies
    • Heppner F. L., Musahl C., Arrighi I., Klein M. A., Rulicke T., Oesch B. et al. (2001) Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science 294: 178-182
    • (2001) Science , vol.294 , pp. 178-182
    • Heppner, F.L.1    Musahl, C.2    Arrighi, I.3    Klein, M.A.4    Rulicke, T.5    Oesch, B.6
  • 55
    • 0037143011 scopus 로고    scopus 로고
    • Postexposure prophylaxis against prion disease with a stimulator of innate immunity
    • Sethi S., Lipford G., Wagner H. and Kretzschmar H. (2002) Postexposure prophylaxis against prion disease with a stimulator of innate immunity. Lancet 360: 229-230
    • (2002) Lancet , vol.360 , pp. 229-230
    • Sethi, S.1    Lipford, G.2    Wagner, H.3    Kretzschmar, H.4
  • 57
    • 0035495399 scopus 로고    scopus 로고
    • Man the barrier! Strategic defences in the intestinal mucosa
    • Nagler-Anderson C. (2001) Man the barrier! Strategic defences in the intestinal mucosa. Nat. Rev. Immunol. 1: 59-67
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 59-67
    • Nagler-Anderson, C.1


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