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Volumn 172, Issue 9, 2004, Pages 5168-5174

Breaking Immune Tolerance to the Prion Protein Using Prion Protein Peptides Plus Oligodeoxynucleotide-CpG in Mice

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 4; OLIGODEOXYNUCLEOTIDE; PEPTIDE DERIVATIVE; PRION PROTEIN; PROTEIN ANTIBODY; T LYMPHOCYTE ANTIGEN;

EID: 2142706520     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.9.5168     Document Type: Article
Times cited : (57)

References (43)
  • 3
    • 0036917840 scopus 로고    scopus 로고
    • The immune system and prion diseases: A relationship of complicity and blindness
    • Aucouturier, P., and C. Carnaud. 2002. The immune system and prion diseases: a relationship of complicity and blindness. J. Leukocyte Biol. 72:1073.
    • (2002) J. Leukocyte Biol. , vol.72 , pp. 1073
    • Aucouturier, P.1    Carnaud, C.2
  • 4
    • 0015843553 scopus 로고
    • Failure to demonstrate a humoral immune response to scrapie infection in mice
    • Porter, D. D., H. G. Porter, and N. A. Cox. 1973. Failure to demonstrate a humoral immune response to scrapie infection in mice. J. Immunol. 111:1407.
    • (1973) J. Immunol. , vol.111 , pp. 1407
    • Porter, D.D.1    Porter, H.G.2    Cox, N.A.3
  • 9
    • 0034856996 scopus 로고    scopus 로고
    • Modulation of proteinase-K resistant prion protein by prion peptide immunization
    • Souan, L., Y. Tal, Y. Felling, I. R. Cohen, A. Taraboulos, and F. Mor. 2001. Modulation of proteinase-K resistant prion protein by prion peptide immunization. Eur. J. Immunol. 31:2338.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 2338
    • Souan, L.1    Tal, Y.2    Felling, Y.3    Cohen, I.R.4    Taraboulos, A.5    Mor, F.6
  • 11
    • 0037705352 scopus 로고    scopus 로고
    • Polyclonal anti-PrP autoantibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells
    • Gilch, S., F. Wopfner, I. Renner-Muller, E. Kremmer, C. Bauer, E. Wolf, G. Brem, M. H. Groschup, and H. M. Schatzl. 2003. Polyclonal anti-PrP autoantibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells. J. Biol. Chem. 278:1852.
    • (2003) J. Biol. Chem. , vol.278 , pp. 1852
    • Gilch, S.1    Wopfner, F.2    Renner-Muller, I.3    Kremmer, E.4    Bauer, C.5    Wolf, E.6    Brem, G.7    Groschup, M.H.8    Schatzl, H.M.9
  • 12
    • 0141782730 scopus 로고    scopus 로고
    • Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent
    • Schwarz, A., O. Kratke, M. Burwinkel, C. Riemer, J. Schultz, P. Henklein, T. Bamme, and M. Baier. 2003. Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent. Neurosci. Lett. 350:187.
    • (2003) Neurosci. Lett. , vol.350 , pp. 187
    • Schwarz, A.1    Kratke, O.2    Burwinkel, M.3    Riemer, C.4    Schultz, J.5    Henklein, P.6    Bamme, T.7    Baier, M.8
  • 15
    • 0037393454 scopus 로고    scopus 로고
    • Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: A case report
    • Nicoll, J. A., D. Wilkinson, C. Holmes, P. Steart, H. Markham, and R. O. Weller. 2003. Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report. Nat. Med. 9:448.
    • (2003) Nat. Med. , vol.9 , pp. 448
    • Nicoll, J.A.1    Wilkinson, D.2    Holmes, C.3    Steart, P.4    Markham, H.5    Weller, R.O.6
  • 17
    • 0041825579 scopus 로고    scopus 로고
    • Cell mediated immune responses against human prion protein
    • Bainbridge, J., and B. Walker. 2003. Cell mediated immune responses against human prion protein. Clin. Exp. Immunol. 133:310.
    • (2003) Clin. Exp. Immunol. , vol.133 , pp. 310
    • Bainbridge, J.1    Walker, B.2
  • 18
    • 85039517730 scopus 로고    scopus 로고
    • Identification of two immunogenic domains of the prion protein, PrP, which activate class II-restricted T cells and elicit antibody responses against the native molecule
    • In press
    • Grégoire, S., C. Logre, P. Metharom, F. Loing, S. Chomillier, M. Bruley Rosset, P. Aucouturier, and C. Carnaud. Identification of two immunogenic domains of the prion protein, PrP, which activate class II-restricted T cells and elicit antibody responses against the native molecule. J. Leukocyte Biol. In press.
    • J. Leukocyte Biol.
    • Grégoire, S.1    Logre, C.2    Metharom, P.3    Loing, F.4    Chomillier, S.5    Bruley Rosset, M.6    Aucouturier, P.7    Carnaud, C.8
  • 20
    • 0024997357 scopus 로고
    • Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals
    • Martin, R., D. Jaraquemada, M. Flerlage, J. Richert, J. Whitaker, E. O. Long, D. E. McFarlin, and H. F. McFarland. 1990. Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals. J. Immunol. 145:540.
    • (1990) J. Immunol. , vol.145 , pp. 540
    • Martin, R.1    Jaraquemada, D.2    Flerlage, M.3    Richert, J.4    Whitaker, J.5    Long, E.O.6    McFarlin, D.E.7    McFarland, H.F.8
  • 21
    • 0038717560 scopus 로고    scopus 로고
    • CpG motifs: The active ingredient in bacterial extracts?
    • Krieg, A. 2003. CpG motifs: the active ingredient in bacterial extracts? Nat. Med. 9:831.
    • (2003) Nat. Med. , vol.9 , pp. 831
    • Krieg, A.1
  • 23
    • 0034777579 scopus 로고    scopus 로고
    • Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amount of IL-12
    • Krug, A., A. Towarowski, S. Britsch, S. Rothenfusser, V. Hornung, R. Bals, T. Giese, H. Engelmann, S. Endres, A. M. Krieg, and G. Hartmann. 2001. Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amount of IL-12. Eur. J. Immunol. 31:3037.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3037
    • Krug, A.1    Towarowski, A.2    Britsch, S.3    Rothenfusser, S.4    Hornung, V.5    Bals, R.6    Giese, T.7    Engelmann, H.8    Endres, S.9    Krieg, A.M.10    Hartmann, G.11
  • 25
    • 0037097633 scopus 로고    scopus 로고
    • Vaccination with tumor peptide in CpG adjuvant protects via IFN-γ-dependent CD4 cell immunity
    • Stern, B. V., B. O. Boehm, and M. Tary-Lehmann. 2002. Vaccination with tumor peptide in CpG adjuvant protects via IFN-γ-dependent CD4 cell immunity. J. Immunol. 168:6099.
    • (2002) J. Immunol. , vol.168 , pp. 6099
    • Stern, B.V.1    Boehm, B.O.2    Tary-Lehmann, M.3
  • 26
    • 0038745486 scopus 로고    scopus 로고
    • Generation of antitumor immunity by cytotoxic T lymphocyte epitope peptide vaccination, CpG-oligodeoxynucleotide adjuvant, and CTLA-4 blockade
    • Davila, E., R. Kennedy, and E. Celis. 2003. Generation of antitumor immunity by cytotoxic T lymphocyte epitope peptide vaccination, CpG-oligodeoxynucleotide adjuvant, and CTLA-4 blockade. Cancer Res. 63:3281.
    • (2003) Cancer Res. , vol.63 , pp. 3281
    • Davila, E.1    Kennedy, R.2    Celis, E.3
  • 30
    • 0030613651 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides act as adjuvants that switch on T helper1 (Th1) immunity
    • Chu, R. S., O. S. Targoni, A. M. Krieg, P. V. Lehman, and C. V. Harding. 1997. CpG oligodeoxynucleotides act as adjuvants that switch on T helper1 (Th1) immunity. J. Exp. Med. 186:1623.
    • (1997) J. Exp. Med. , vol.186 , pp. 1623
    • Chu, R.S.1    Targoni, O.S.2    Krieg, A.M.3    Lehman, P.V.4    Harding, C.V.5
  • 31
    • 0030239828 scopus 로고    scopus 로고
    • Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
    • Ballas, Z. K., W. L. Rasmussen, and M. A. Krieg. 1996. Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J. Immunol. 157:1840.
    • (1996) J. Immunol. , vol.157 , pp. 1840
    • Ballas, Z.K.1    Rasmussen, W.L.2    Krieg, M.A.3
  • 32
    • 0021088777 scopus 로고
    • One out of five peripheral blood lymphocytes is activated to high rate of Ig production by human alloreactive T-cell clones
    • Lanzavecchia, A. 1983. One out of five peripheral blood lymphocytes is activated to high rate of Ig production by human alloreactive T-cell clones. Eur. J. Immunol. 13:820.
    • (1983) Eur. J. Immunol. , vol.13 , pp. 820
    • Lanzavecchia, A.1
  • 33
    • 0032775793 scopus 로고    scopus 로고
    • Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences
    • Martin-Orozco, E., H. Kobayashi, J. Van Uden, M. D. Nguyen, R. S. Kornbluth, and E. Raz. 1999. Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences. Int. Immunol. 11:1111.
    • (1999) Int. Immunol. , vol.11 , pp. 1111
    • Martin-Orozco, E.1    Kobayashi, H.2    Van Uden, J.3    Nguyen, M.D.4    Kornbluth, R.S.5    Raz, E.6
  • 34
    • 0034996564 scopus 로고    scopus 로고
    • Avoiding tolerance to prostatic antigens with subdominant peptide epitopes
    • Grossmann, M. E., E. Davila, and E. Celis. 2001. Avoiding tolerance to prostatic antigens with subdominant peptide epitopes. J. Immunother. 24:237.
    • (2001) J. Immunother. , vol.24 , pp. 237
    • Grossmann, M.E.1    Davila, E.2    Celis, E.3
  • 35
    • 0036721808 scopus 로고    scopus 로고
    • Activation of APCs through CD40 or Toll-like receptor-9 overcomes tolerance and precipitates autoimmune disease
    • Hiroshi, T., L. P. Williams, and B. M. Segal. 2002. Activation of APCs through CD40 or Toll-like receptor-9 overcomes tolerance and precipitates autoimmune disease. J. Immunol. 169:2781.
    • (2002) J. Immunol. , vol.169 , pp. 2781
    • Hiroshi, T.1    Williams, L.P.2    Segal, B.M.3
  • 36
    • 0029066886 scopus 로고
    • Species-specific in cell-free conversion of prion protein to protease-resistant forms: A model for the scrapie species barriers
    • Kocisco, D. A., S. A. Priola, G. J. Raymond, B. Chesebro, P. T. Landsbury, Jr., and B. Caughey. 1995. Species-specific in cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barriers. Proc. Natl. Acad. Sci. USA 92:3923.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3923
    • Kocisco, D.A.1    Priola, S.A.2    Raymond, G.J.3    Chesebro, B.4    Landsbury Jr., P.T.5    Caughey, B.6
  • 38
    • 0035979274 scopus 로고    scopus 로고
    • Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
    • Enari, M., E. Flechsig, and C. Weissmann. 2001. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc. Natl. Acad. Sci. USA 98:9295.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9295
    • Enari, M.1    Flechsig, E.2    Weissmann, C.3
  • 41
    • 0037143011 scopus 로고    scopus 로고
    • Postexposure prophylaxis against prion disease with a stimulator of innate immunity
    • Sethi, S., G. Lipford, H. Wagner, and H. Kretzschmar. 2002. Postexposure prophylaxis against prion disease with a stimulator of innate immunity. Lancet 360:22930.
    • (2002) Lancet , vol.360 , pp. 22930
    • Sethi, S.1    Lipford, G.2    Wagner, H.3    Kretzschmar, H.4
  • 42
    • 12244259034 scopus 로고    scopus 로고
    • Complete Freund's adjuvant immunization prolongs survival in experimental prion disease in mice
    • Tal, Y., L. Souan, I. R. Cohen, Z. Meiner, A. Taraboulos, and F. Mor. 2003. Complete Freund's adjuvant immunization prolongs survival in experimental prion disease in mice. J. Neurosci. Res. 71:286.
    • (2003) J. Neurosci. Res. , vol.71 , pp. 286
    • Tal, Y.1    Souan, L.2    Cohen, I.R.3    Meiner, Z.4    Taraboulos, A.5    Mor, F.6


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