Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 14, 1996, Pages 7279-7282

  Williamson, R Anthony ^a   Peretz, David ^b   Smorodinsky, Nechama ^b   Bastidas, Raiza ^a   Serban, Hana ^b   Mehlhorn, Ingrid ^b   Dearmond, Stephen J ^b   Prusiner, Stanley B ^b   Burton, Dennis R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

gene ablation; mouse antibody libraries; phage display; prion disease; scrapie

Indexed keywords

MONOCLONAL ANTIBODY;

ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; BACTERIOPHAGE; CENTRAL NERVOUS SYSTEM INFECTION; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; SHEEP DISEASE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BASE SEQUENCE; CRICETINAE; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNE TOLERANCE; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; MESOCRICETUS; MICE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PRION DISEASES; PRIONS; RECOMBINANT PROTEINS;

EID: 0030013173     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.14.7279     Document Type: Article

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