메뉴 건너뛰기




Volumn 21, Issue 3, 2007, Pages 367-377

Cyclooxygenase (COX) inhibitors and the intestine

Author keywords

Heat shock protein; Nonsteroidal anti inflammatory drugs; Nuclear factor KB; p38 Mitogen activated protein kinases; Peroxisome proliferator activated receptor gamma

Indexed keywords

HEAT SHOCK PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN KINASE B;

EID: 34249297006     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2007)21[367:CCIATI]2.0.CO;2     Document Type: Article
Times cited : (40)

References (88)
  • 1
    • 0034527045 scopus 로고    scopus 로고
    • The fight against rheumatism: From willow bark to COX-1 sparing drugs
    • Vane JR. The fight against rheumatism: From willow bark to COX-1 sparing drugs. J Physiol Pharm 2000;51:573-586.
    • (2000) J Physiol Pharm , vol.51 , pp. 573-586
    • Vane, J.R.1
  • 2
    • 0142165030 scopus 로고    scopus 로고
    • The mechanism of action of aspirin
    • Vane JR, Bolting RM. The mechanism of action of aspirin. Thromb Res 2003;110:255-258.
    • (2003) Thromb Res , vol.110 , pp. 255-258
    • Vane, J.R.1    Bolting, R.M.2
  • 3
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action of aspirin-like drugs
    • Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action of aspirin-like drugs. Nat New Biol 1971;231:232-235.
    • (1971) Nat New Biol , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 4
    • 0017094438 scopus 로고
    • Purification of the cyclo-oxygenase that forms prostaglandins: Demonstration of two forms of iron in the holoenzyme
    • Hemler M, Lands WEM, Smith WL. Purification of the cyclo-oxygenase that forms prostaglandins: Demonstration of two forms of iron in the holoenzyme. J Biol Chem 1976;251:5575-5579.
    • (1976) J Biol Chem , vol.251 , pp. 5575-5579
    • Hemler, M.1    Lands, W.E.M.2    Smith, W.L.3
  • 5
    • 0025754779 scopus 로고
    • Expression of a mitogen-responsive gene encoding prostaglandin synthesis is regulated by mRNA splicing
    • Xie W, Chipman JG, Robertson DL, et al. Expression of a mitogen-responsive gene encoding prostaglandin synthesis is regulated by mRNA splicing. Proc Natl Acad Sci USA 1991;88:2692-2696.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2692-2696
    • Xie, W.1    Chipman, J.G.2    Robertson, D.L.3
  • 6
    • 0034685192 scopus 로고    scopus 로고
    • COX-1, COX-2 and COX-3 and the future treatment of chronic inflammatory disease
    • Willoughby DA, Moore AR, Colville-Nash PR. COX-1, COX-2 and COX-3 and the future treatment of chronic inflammatory disease. Lancet 2000;355:646-648.
    • (2000) Lancet , vol.355 , pp. 646-648
    • Willoughby, D.A.1    Moore, A.R.2    Colville-Nash, P.R.3
  • 7
    • 0037108979 scopus 로고    scopus 로고
    • Cox-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure and expression
    • Chandrasekharan NV, Dai H, Roos KL, et al. Cox-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure and expression. Proc Natl Acad Sci USA 2002;99:13926-13931.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13926-13931
    • Chandrasekharan, N.V.1    Dai, H.2    Roos, K.L.3
  • 8
    • 27744529775 scopus 로고    scopus 로고
    • Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: Evidence for intron 1 retention
    • Qin N, Zhang SP, Reitz TL, et al. Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: Evidence for intron 1 retention. J Pharmacol Exp Ther 2005;315:1298-1305.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 1298-1305
    • Qin, N.1    Zhang, S.P.2    Reitz, T.L.3
  • 9
    • 12844253982 scopus 로고    scopus 로고
    • Davies NM, Good RL, Roupe KA, et al. Cyclooxygenase-3: Axiom, dogma, anomaly, enigma or splice error? - Not as easy as 1, 2, 3. J Pharm Pharmaceut Sci 2004;7:217-226.
    • Davies NM, Good RL, Roupe KA, et al. Cyclooxygenase-3: Axiom, dogma, anomaly, enigma or splice error? - Not as easy as 1, 2, 3. J Pharm Pharmaceut Sci 2004;7:217-226.
  • 10
    • 24144447706 scopus 로고    scopus 로고
    • Intron 1 retaining cyclooxygenase 1 splice variant is induced by osmotic stress in human intestinal epithelial cells
    • Nurmi JT, Puolakkainen PA, Rautonen NE. Intron 1 retaining cyclooxygenase 1 splice variant is induced by osmotic stress in human intestinal epithelial cells. Prostaglandins Leukot Essent Fatty Acids 2005;73:343-350.
    • (2005) Prostaglandins Leukot Essent Fatty Acids , vol.73 , pp. 343-350
    • Nurmi, J.T.1    Puolakkainen, P.A.2    Rautonen, N.E.3
  • 11
    • 27544432733 scopus 로고    scopus 로고
    • Cyclooxygenase variants: The role of alternative splicing
    • Roos KLT, Simmons DL. Cyclooxygenase variants: The role of alternative splicing. Biochem Biophys Res Comm 2005;338:62-69.
    • (2005) Biochem Biophys Res Comm , vol.338 , pp. 62-69
    • Roos, K.L.T.1    Simmons, D.L.2
  • 12
    • 32244447306 scopus 로고    scopus 로고
    • Gastrointestinal inflammation: A central component of mucosal defense and repair
    • Martin GR, Wallace JL. Gastrointestinal inflammation: A central component of mucosal defense and repair. Exp Biol Med (Maywood) 2006;231:130-137.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 130-137
    • Martin, G.R.1    Wallace, J.L.2
  • 13
    • 23644433791 scopus 로고    scopus 로고
    • COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice
    • Hiratsuka T, Futagami S, Tatsuguchi A, et al. COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice. Scand J Gastroenterol 2005;40:903-913.
    • (2005) Scand J Gastroenterol , vol.40 , pp. 903-913
    • Hiratsuka, T.1    Futagami, S.2    Tatsuguchi, A.3
  • 14
    • 14844307023 scopus 로고    scopus 로고
    • Mucosal expression of cyclooxygenase isoforms 1 and 2 is increased with worsening damage to the gastric mucosa
    • Bhandari P, Bateman AC, Mehta RL, et al. Mucosal expression of cyclooxygenase isoforms 1 and 2 is increased with worsening damage to the gastric mucosa. Histopathology 2005;46:280-286.
    • (2005) Histopathology , vol.46 , pp. 280-286
    • Bhandari, P.1    Bateman, A.C.2    Mehta, R.L.3
  • 15
    • 33645353617 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-1 and cyclooxygenase-2 in human renal allograft rejection - A prospective study
    • Hoffmann U, Banas B, Kruger B, et al. Expression of cyclooxygenase-1 and cyclooxygenase-2 in human renal allograft rejection - A prospective study. Transpl Int 2006;19:203-212.
    • (2006) Transpl Int , vol.19 , pp. 203-212
    • Hoffmann, U.1    Banas, B.2    Kruger, B.3
  • 16
    • 3042571674 scopus 로고    scopus 로고
    • Effects of flunixin meglumine or etodolac treatment on mucosal recovery of equine jejunum after ischemia
    • Tomlinson JE, Wilder BO, Young KM, et al. Effects of flunixin meglumine or etodolac treatment on mucosal recovery of equine jejunum after ischemia. Am J Vet Res 2004;65:761-769.
    • (2004) Am J Vet Res , vol.65 , pp. 761-769
    • Tomlinson, J.E.1    Wilder, B.O.2    Young, K.M.3
  • 17
    • 27544489924 scopus 로고    scopus 로고
    • An intronic enhancer regulated COX-1 gene expression
    • DeLong CJ, Smith WL. An intronic enhancer regulated COX-1 gene expression. Biochem Biophys Res Commun 2005;338:53-61.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 53-61
    • DeLong, C.J.1    Smith, W.L.2
  • 18
    • 23844502011 scopus 로고    scopus 로고
    • Is COX-2 a 'collateral' target in cancer prevention?
    • Kashfi K, Rigas B. Is COX-2 a 'collateral' target in cancer prevention? Biochem Soc Trans 2005;33:724-727.
    • (2005) Biochem Soc Trans , vol.33 , pp. 724-727
    • Kashfi, K.1    Rigas, B.2
  • 19
    • 11144286024 scopus 로고    scopus 로고
    • Constitutive and functional expression of cyclooxygenase 2 in the murine proximal colon
    • Porcher C, Horowitz B, Ward SM, et al. Constitutive and functional expression of cyclooxygenase 2 in the murine proximal colon. Neurogastroenterol Motil 2004;16:785-799.
    • (2004) Neurogastroenterol Motil , vol.16 , pp. 785-799
    • Porcher, C.1    Horowitz, B.2    Ward, S.M.3
  • 20
    • 15044358766 scopus 로고    scopus 로고
    • Differential expression of COX-1 and COX-2 in the gastrointestinal tract of the rat
    • Haworth R, Oakley K, McCormack N, et al. Differential expression of COX-1 and COX-2 in the gastrointestinal tract of the rat. Toxicol Pathol 2005;33:239-245.
    • (2005) Toxicol Pathol , vol.33 , pp. 239-245
    • Haworth, R.1    Oakley, K.2    McCormack, N.3
  • 21
    • 0029907525 scopus 로고    scopus 로고
    • Exacerbation of inflammation- associated colonic injury in rat through inhibition of cyclooxygenase-2
    • Reuter BK, Asfaha S, Buret A, et al. Exacerbation of inflammation- associated colonic injury in rat through inhibition of cyclooxygenase-2. J Clin Invest 1996;98:2076-2085.
    • (1996) J Clin Invest , vol.98 , pp. 2076-2085
    • Reuter, B.K.1    Asfaha, S.2    Buret, A.3
  • 22
    • 0031884213 scopus 로고    scopus 로고
    • Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro-intestinal ulcer models in rats
    • Schmassmann A, Peskar BM, Stettler C, et al. Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro-intestinal ulcer models in rats. Br J Pharmacol 1998;123:795-804.
    • (1998) Br J Pharmacol , vol.123 , pp. 795-804
    • Schmassmann, A.1    Peskar, B.M.2    Stettler, C.3
  • 23
    • 0033613852 scopus 로고    scopus 로고
    • Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways
    • Murakami M, Kambe T, Shimbara S, et al. Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways. J Biol Chem 1999;274:3103-3115.
    • (1999) J Biol Chem , vol.274 , pp. 3103-3115
    • Murakami, M.1    Kambe, T.2    Shimbara, S.3
  • 24
    • 23944439888 scopus 로고    scopus 로고
    • Sequential induction of prostaglandin E and D synthases in inflammation
    • Schuligoi R, Grill M, Heinemann A, et al. Sequential induction of prostaglandin E and D synthases in inflammation. Biochem Biophys Res Commun 2005;335:684-689.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 684-689
    • Schuligoi, R.1    Grill, M.2    Heinemann, A.3
  • 25
    • 33644664887 scopus 로고    scopus 로고
    • Contrasting effects of peroxisome-proliferator-activated receptor (PPAR) gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: Evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14 prostaglandin J2
    • Bianchi A, Moulin D, Sebillaud S, et al. Contrasting effects of peroxisome-proliferator-activated receptor (PPAR) gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: Evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14 prostaglandin J2. Arthritis Res Ther 2005;7:R1325-1337.
    • (2005) Arthritis Res Ther , vol.7
    • Bianchi, A.1    Moulin, D.2    Sebillaud, S.3
  • 26
    • 0035053973 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins: New insights on biological activities and cellular targets
    • Straus DS, Glass CK. Cyclopentenone prostaglandins: New insights on biological activities and cellular targets. Med Res Rev 2001;21:185-210.
    • (2001) Med Res Rev , vol.21 , pp. 185-210
    • Straus, D.S.1    Glass, C.K.2
  • 27
    • 0034986726 scopus 로고    scopus 로고
    • COX in a crystal ball: Current status and future promise of prostaglandin research
    • Fitzgerald GA, Loll P. COX in a crystal ball: Current status and future promise of prostaglandin research. J Clin. Invest 2001;107:1335-1337.
    • (2001) J Clin. Invest , vol.107 , pp. 1335-1337
    • Fitzgerald, G.A.1    Loll, P.2
  • 28
    • 0035662474 scopus 로고    scopus 로고
    • Dual acting antiinflammatory drugs: A reappraisal
    • Bertolini A, Ottani A, Sandrini M. Dual acting antiinflammatory drugs: A reappraisal. Pharmacol Res 2000;44:437-450.
    • (2000) Pharmacol Res , vol.44 , pp. 437-450
    • Bertolini, A.1    Ottani, A.2    Sandrini, M.3
  • 29
    • 0030461132 scopus 로고    scopus 로고
    • Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
    • Kurumbail RG, Stevens AM, Gierse JK, et al. Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature 1996;384:644-648.
    • (1996) Nature , vol.384 , pp. 644-648
    • Kurumbail, R.G.1    Stevens, A.M.2    Gierse, J.K.3
  • 30
    • 1242271208 scopus 로고    scopus 로고
    • 3-Phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells
    • Kulp SK, Yang YT, Hung CC, et al. 3-Phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells. Cancer Res 2004;64:1444-1451.
    • (2004) Cancer Res , vol.64 , pp. 1444-1451
    • Kulp, S.K.1    Yang, Y.T.2    Hung, C.C.3
  • 31
    • 17744418769 scopus 로고    scopus 로고
    • The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
    • Steinbach G, Lynch PM, Phillips RK, et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 2000;342:1946-1952.
    • (2000) N Engl J Med , vol.342 , pp. 1946-1952
    • Steinbach, G.1    Lynch, P.M.2    Phillips, R.K.3
  • 32
    • 0033575760 scopus 로고    scopus 로고
    • Malignant transformation and antineoplastic actions of nonsteroidal antiin-flammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts
    • Zhang X, Morham SG, Langenbach R, et al. Malignant transformation and antineoplastic actions of nonsteroidal antiin-flammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. J Exp Med 1999;190:451-159.
    • (1999) J Exp Med , vol.190 , pp. 451-159
    • Zhang, X.1    Morham, S.G.2    Langenbach, R.3
  • 33
    • 0034816925 scopus 로고    scopus 로고
    • Cyclooxygenase-independent actions of cyclooxygenase inhibitors
    • Tegeder I, Pfeilschifter J, Geisslinger G. Cyclooxygenase-independent actions of cyclooxygenase inhibitors. FASEB J 2001;15:2057-2072.
    • (2001) FASEB J , vol.15 , pp. 2057-2072
    • Tegeder, I.1    Pfeilschifter, J.2    Geisslinger, G.3
  • 34
    • 0028300256 scopus 로고
    • Antinociceptive actions of R(-)-flurbiprofen-a non-cyclooxygenase inhibiting 2-arylpropionic acid-in rats
    • Geisslinger G, Ferreira SH, Menzel S, et al. Antinociceptive actions of R(-)-flurbiprofen-a non-cyclooxygenase inhibiting 2-arylpropionic acid-in rats. Life Sci 1994;54:PL173-PL177.
    • (1994) Life Sci , vol.54
    • Geisslinger, G.1    Ferreira, S.H.2    Menzel, S.3
  • 35
    • 13844273087 scopus 로고    scopus 로고
    • PI3K-Akt pathway: Its functions and alterations in human cancer
    • Osaki M, Oshimura M, Ito H. PI3K-Akt pathway: Its functions and alterations in human cancer. Apoptosis 2004;9:667-676.
    • (2004) Apoptosis , vol.9 , pp. 667-676
    • Osaki, M.1    Oshimura, M.2    Ito, H.3
  • 36
    • 3042562279 scopus 로고    scopus 로고
    • From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors
    • Zhu J, Huang JW, Tseng PH, et al. From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors. Cancer Res 2004;64:4309-4318.
    • (2004) Cancer Res , vol.64 , pp. 4309-4318
    • Zhu, J.1    Huang, J.W.2    Tseng, P.H.3
  • 37
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Di Cristofano A, Pandolfi PP. The multiple roles of PTEN in tumor suppression. Cell 2000;100:387-390.
    • (2000) Cell , vol.100 , pp. 387-390
    • Di Cristofano, A.1    Pandolfi, P.P.2
  • 38
    • 16344389993 scopus 로고    scopus 로고
    • Celecoxib inhibits prostate cancer growth: Evidence of a cyclooxygenase-2-independent mechanism
    • Patel MI, Subbaramaiah K, Du B, et al. Celecoxib inhibits prostate cancer growth: Evidence of a cyclooxygenase-2-independent mechanism. Clin Cancer Res 2005;11:1999-2007.
    • (2005) Clin Cancer Res , vol.11 , pp. 1999-2007
    • Patel, M.I.1    Subbaramaiah, K.2    Du, B.3
  • 39
    • 22044448663 scopus 로고    scopus 로고
    • Celecoxib induces hemeoxygenase expression in glomerular mesangial cells
    • Hou CC, Hung SL, Kao SH, et al. Celecoxib induces hemeoxygenase expression in glomerular mesangial cells. Ann NY Acad Sci 2005;1042:235-245.
    • (2005) Ann NY Acad Sci , vol.1042 , pp. 235-245
    • Hou, C.C.1    Hung, S.L.2    Kao, S.H.3
  • 40
    • 1842839916 scopus 로고    scopus 로고
    • Heme oxygenase-1 induction by hemin protects against gut ischemia/ reperfusion injury
    • Attuwaybi BO, Kozar RA, Moore-Olufemi SD, et al. Heme oxygenase-1 induction by hemin protects against gut ischemia/ reperfusion injury. J Surg Res 2004;118:53-57.
    • (2004) J Surg Res , vol.118 , pp. 53-57
    • Attuwaybi, B.O.1    Kozar, R.A.2    Moore-Olufemi, S.D.3
  • 41
    • 23644436020 scopus 로고    scopus 로고
    • Deshane J, Wright M, Agarwal A. Heme oxygenase-1 expression in disease states. Acta Biochim Pol2005, 52:273-284.
    • Deshane J, Wright M, Agarwal A. Heme oxygenase-1 expression in disease states. Acta Biochim Pol2005, 52:273-284.
  • 42
    • 0347991871 scopus 로고    scopus 로고
    • Akt2, phosphatidylinositol 3-kinase, and PTEN are in lipid rafts of intestinal cells: Role in absorption and differentiation
    • Li X, Leu S, Cheong A, et al. Akt2, phosphatidylinositol 3-kinase, and PTEN are in lipid rafts of intestinal cells: Role in absorption and differentiation. Gastroenterology 2004;126:122-135.
    • (2004) Gastroenterology , vol.126 , pp. 122-135
    • Li, X.1    Leu, S.2    Cheong, A.3
  • 43
    • 0034304851 scopus 로고    scopus 로고
    • Lipid rafts and signal transduction
    • Simons K, Toomre D. Lipid rafts and signal transduction. Nat rev mol Cell Biol 2000;1:31-49.
    • (2000) Nat rev mol Cell Biol , vol.1 , pp. 31-49
    • Simons, K.1    Toomre, D.2
  • 44
    • 0032946862 scopus 로고    scopus 로고
    • Prostaglandin-induced recovery of barrier function in porcine ileum is triggered by chloride secretion
    • Blikslager AT, Roberts MC, Argenzio RA. Prostaglandin-induced recovery of barrier function in porcine ileum is triggered by chloride secretion. Am J Physiol Gastrointest Liver Physiol 1999;276:G28-G36.
    • (1999) Am J Physiol Gastrointest Liver Physiol , vol.276
    • Blikslager, A.T.1    Roberts, M.C.2    Argenzio, R.A.3
  • 45
    • 0037227666 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase (PI3'K) signaling is required for prostaglandin-induced mucosal recovery in ischemia-injured porcine ileum
    • Little D, Dean RA, Young KM, et al. Phosphatidylinositol-3-kinase (PI3'K) signaling is required for prostaglandin-induced mucosal recovery in ischemia-injured porcine ileum. Am J Physiol Gastrointest Liver Physiol 2003;284:G46-56.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284
    • Little, D.1    Dean, R.A.2    Young, K.M.3
  • 46
    • 0030804842 scopus 로고    scopus 로고
    • Accumulation of arachidonic acid in ischemic/reperfused cardiac tissue: Possible causes and consequences
    • Van der Vusse GJ, Reneman RS, Van Bilsen M. Accumulation of arachidonic acid in ischemic/reperfused cardiac tissue: Possible causes and consequences. Prostaglandins Leukot Essent Fatty Acids 1997;57:85-93.
    • (1997) Prostaglandins Leukot Essent Fatty Acids , vol.57 , pp. 85-93
    • Van der Vusse, G.J.1    Reneman, R.S.2    Van Bilsen, M.3
  • 47
    • 0035092246 scopus 로고    scopus 로고
    • Aspirin, but not the more selective cyclooxygenase (COX)-2 inhibitors meloxicam and SC58125, aggravates postischaemic cardiac dysfunction, independent of COX function
    • Heindl B, Becker BF. Aspirin, but not the more selective cyclooxygenase (COX)-2 inhibitors meloxicam and SC58125, aggravates postischaemic cardiac dysfunction, independent of COX function. Naunyn Schmiedebergs Arch Pharmacol 2001;363:233-40.
    • (2001) Naunyn Schmiedebergs Arch Pharmacol , vol.363 , pp. 233-240
    • Heindl, B.1    Becker, B.F.2
  • 48
    • 33645876790 scopus 로고    scopus 로고
    • Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary γ-Linolenic acid
    • Yu Z, Ng VY, Su P, et al. Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary γ-Linolenic acid. J Pharmacol Exp Ther 2006;317:732-738.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 732-738
    • Yu, Z.1    Ng, V.Y.2    Su, P.3
  • 49
    • 27744561554 scopus 로고    scopus 로고
    • Cardiovascular complications of non-steroidal anti-inflammatory drugs
    • Fosslien E. Cardiovascular complications of non-steroidal anti-inflammatory drugs. Ann Clin Lab Sci 2005;35:347-385.
    • (2005) Ann Clin Lab Sci , vol.35 , pp. 347-385
    • Fosslien, E.1
  • 50
    • 0037652327 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs and a selective cyclooxygenase 2 inhibitor uncouple mitochondria in intact cells
    • Krause MM, Brand MD, Krauss S, et al. Nonsteroidal antiinflammatory drugs and a selective cyclooxygenase 2 inhibitor uncouple mitochondria in intact cells. Arthritis Rheum 2003;48:1438-1444.
    • (2003) Arthritis Rheum , vol.48 , pp. 1438-1444
    • Krause, M.M.1    Brand, M.D.2    Krauss, S.3
  • 51
    • 0031036081 scopus 로고    scopus 로고
    • Uncoupling effects of diclofenac and aspirin in the perfused liver and isolated hepatic mitochondria of rat
    • Petrescu I, Tarba C. Uncoupling effects of diclofenac and aspirin in the perfused liver and isolated hepatic mitochondria of rat. Biochim Biophys Acta 1997;1318:385-394.
    • (1997) Biochim Biophys Acta , vol.1318 , pp. 385-394
    • Petrescu, I.1    Tarba, C.2
  • 52
    • 0033811024 scopus 로고    scopus 로고
    • Comparison of the intestinal toxicity of celecoxib, a selective COX-2 inhibitor, and indomethacin in the experimental rat
    • Tibble JA, Sigthorsson G, Foster R, et al. Comparison of the intestinal toxicity of celecoxib, a selective COX-2 inhibitor, and indomethacin in the experimental rat. Scand J Gastroenterol 2000;35:802-807.
    • (2000) Scand J Gastroenterol , vol.35 , pp. 802-807
    • Tibble, J.A.1    Sigthorsson, G.2    Foster, R.3
  • 53
    • 0344097396 scopus 로고    scopus 로고
    • Inhibition and uncoupling of oxidative phosphorylation by nonsteroidal antiinflammatory drugs
    • Moreno-Sanchez R, Bravo C, Vasquez C, et al. Inhibition and uncoupling of oxidative phosphorylation by nonsteroidal antiinflammatory drugs. Biochem Pharmacol 1999;57:743-752.
    • (1999) Biochem Pharmacol , vol.57 , pp. 743-752
    • Moreno-Sanchez, R.1    Bravo, C.2    Vasquez, C.3
  • 54
    • 8644243944 scopus 로고    scopus 로고
    • Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: Comparison to sulfonamide COX-2 inhibitors and NSAIDs
    • Walter MF, Jacob RF, Day CA, et al. Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: Comparison to sulfonamide COX-2 inhibitors and NSAIDs. Atherosclerosis 2004;177:235-243.
    • (2004) Atherosclerosis , vol.177 , pp. 235-243
    • Walter, M.F.1    Jacob, R.F.2    Day, C.A.3
  • 55
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I, Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990;347:645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 56
    • 0033793133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
    • Chinetti G, Fruchart JC, Staels B. Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm Res 2000;49:497-505.
    • (2000) Inflamm Res , vol.49 , pp. 497-505
    • Chinetti, G.1    Fruchart, J.C.2    Staels, B.3
  • 57
    • 0028321529 scopus 로고
    • Differential expression and activation of a family of murine peroxisome proliferator-activated receptors
    • Kliewer SA, Forman BM, Blumberg B, et al. Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Nat Acad Sci USA 1994;91:7355-7359.
    • (1994) Proc Nat Acad Sci USA , vol.91 , pp. 7355-7359
    • Kliewer, S.A.1    Forman, B.M.2    Blumberg, B.3
  • 58
    • 0034965596 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in inflammation control
    • Delerive P, Fruchart J-C, Staels B. Peroxisome proliferator-activated receptors in inflammation control. J Endocrin 2001;169:453-459.
    • (2001) J Endocrin , vol.169 , pp. 453-459
    • Delerive, P.1    Fruchart, J.-C.2    Staels, B.3
  • 59
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten S, Desvergne B, Wahli W. Roles of PPARs in health and disease. Nature 2000;405:421-424.
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 60
    • 0035894284 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H2 synthases by ibuprofen, naproxen, and indomethacin
    • Jaradat MS, Wongsud B, Phornchirasilp S, et al. Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H2 synthases by ibuprofen, naproxen, and indomethacin. Biochem Pharmacol 2001;62:1587-1595.
    • (2001) Biochem Pharmacol , vol.62 , pp. 1587-1595
    • Jaradat, M.S.1    Wongsud, B.2    Phornchirasilp, S.3
  • 61
    • 4143070446 scopus 로고    scopus 로고
    • 15-deoxy-Δ12,14- prostaglandin J2 inhibits IL-1β-induced IKK enzymatic activity and IκBα degradation in rat chondrocytes through a PPARγ- independent pathway
    • Boyault S, Bianchi A, Moulin D, et al. 15-deoxy-Δ12,14- prostaglandin J2 inhibits IL-1β-induced IKK enzymatic activity and IκBα degradation in rat chondrocytes through a PPARγ- independent pathway. FEBS Letters 2004;572:33-40.
    • (2004) FEBS Letters , vol.572 , pp. 33-40
    • Boyault, S.1    Bianchi, A.2    Moulin, D.3
  • 62
    • 0035127894 scopus 로고    scopus 로고
    • Endogenous PPARγ mediates anti-inflammatory activity in murine ischemia-reperfusion injury
    • Nakajima A, Wada K, Miki H, et al. Endogenous PPARγ mediates anti-inflammatory activity in murine ischemia-reperfusion injury. Gastroenterology 2001;120:460-469.
    • (2001) Gastroenterology , vol.120 , pp. 460-469
    • Nakajima, A.1    Wada, K.2    Miki, H.3
  • 63
    • 0242526756 scopus 로고    scopus 로고
    • Phosphorylation of PPARγ via active ERK1/2 leads to its physical association with p65 and inhibition of NF-κB
    • Chen F, Wang M, O'Connor JP, et al. Phosphorylation of PPARγ via active ERK1/2 leads to its physical association with p65 and inhibition of NF-κB. J Cell Biochem 2003;90:732-744.
    • (2003) J Cell Biochem , vol.90 , pp. 732-744
    • Chen, F.1    Wang, M.2    O'Connor, J.P.3
  • 64
    • 0031057517 scopus 로고    scopus 로고
    • Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
    • Adams M, Reginato MJ, Shao D, et al. Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J Biol Chem 1997;272:5128-5132.
    • (1997) J Biol Chem , vol.272 , pp. 5128-5132
    • Adams, M.1    Reginato, M.J.2    Shao, D.3
  • 65
    • 20444497357 scopus 로고    scopus 로고
    • Receptor-independent actions of PPAR thiazolidinedione agonists: Is mitochondrial function the key?
    • Feinstein DL, Spagnolo A, Akar C, et al. Receptor-independent actions of PPAR thiazolidinedione agonists: Is mitochondrial function the key? Biochem Pharm 2005;70:177-188.
    • (2005) Biochem Pharm , vol.70 , pp. 177-188
    • Feinstein, D.L.1    Spagnolo, A.2    Akar, C.3
  • 66
    • 19944430692 scopus 로고    scopus 로고
    • A PPAR-gamma ligand, 15-deoxy-Delta 12,14-prostaglandin J(2), inhibited gastric mucosal injury induced by ischemia-reperfusion in rats
    • Takagi T, Naito Y, Ichikawa H, et al. A PPAR-gamma ligand, 15-deoxy-Delta 12,14-prostaglandin J(2), inhibited gastric mucosal injury induced by ischemia-reperfusion in rats. Redox Rep 2004;9:376-381.
    • (2004) Redox Rep , vol.9 , pp. 376-381
    • Takagi, T.1    Naito, Y.2    Ichikawa, H.3
  • 67
    • 19944370429 scopus 로고    scopus 로고
    • The selective cyclooxygenase-2 inhibitor celecoxib modulates the formation of vasoconstrictor eicosanoids and activates PPARγ. Influence of albumin
    • López-Parra M, Clària J, Titos E, et al. The selective cyclooxygenase-2 inhibitor celecoxib modulates the formation of vasoconstrictor eicosanoids and activates PPARγ. Influence of albumin. J Hepatol 2005;42:75-81.
    • (2005) J Hepatol , vol.42 , pp. 75-81
    • López-Parra, M.1    Clària, J.2    Titos, E.3
  • 68
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator- activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs
    • Lehmann JM, Lenhard JM, Oliver BB, et al. Peroxisome proliferator- activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem 1997;272:3406-3410.
    • (1997) J Biol Chem , vol.272 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3
  • 69
    • 0033583029 scopus 로고    scopus 로고
    • Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells
    • Meade EA, McIntyre TM, Zimmerman GA, et al. Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells. J Biol Chem 1999;274:8328-8334.
    • (1999) J Biol Chem , vol.274 , pp. 8328-8334
    • Meade, E.A.1    McIntyre, T.M.2    Zimmerman, G.A.3
  • 70
    • 27644481210 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma mediates protection against cyclooxygenase-2-induced gut dysfunction in a rodent model of mesenteric ischemia/reperfusion
    • Sato N, Kozar RA, Zou L, et al. Peroxisome proliferator-activated receptor gamma mediates protection against cyclooxygenase-2-induced gut dysfunction in a rodent model of mesenteric ischemia/reperfusion. Shock 2005;24:462-469.
    • (2005) Shock , vol.24 , pp. 462-469
    • Sato, N.1    Kozar, R.A.2    Zou, L.3
  • 71
    • 33645802403 scopus 로고    scopus 로고
    • Differential induction of PPARγ by luminal glutamine and iNOS by luminal arginine in the rodent post ischemic small bowel
    • Sato N, Moore FA, Kone BC, et al. Differential induction of PPARγ by luminal glutamine and iNOS by luminal arginine in the rodent post ischemic small bowel. Am J Physiol Gastrointest Liver Physiol 2006;290:616-623.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , pp. 616-623
    • Sato, N.1    Moore, F.A.2    Kone, B.C.3
  • 72
    • 0038587747 scopus 로고    scopus 로고
    • The two faces of IKK and NF-κB inhibition: Prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion
    • Chen LW, Egan L, Li ZW, et al. The two faces of IKK and NF-κB inhibition: Prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat Med 2003;9:575-581.
    • (2003) Nat Med , vol.9 , pp. 575-581
    • Chen, L.W.1    Egan, L.2    Li, Z.W.3
  • 73
    • 29744443925 scopus 로고    scopus 로고
    • Transcription factor NF-κB: A sensor for smoke and stress signals
    • Ahn KS, Aggarwal BB. Transcription factor NF-κB: A sensor for smoke and stress signals. Ann NY Acad Sci 2005;1056:218-233.
    • (2005) Ann NY Acad Sci , vol.1056 , pp. 218-233
    • Ahn, K.S.1    Aggarwal, B.B.2
  • 74
    • 0038481659 scopus 로고    scopus 로고
    • Inhibitory effects of indomethacin and meloxicam on NF-kappa B in mouse peritoneal macrophages
    • Hu YF, Guo Y, Cheng GF. Inhibitory effects of indomethacin and meloxicam on NF-kappa B in mouse peritoneal macrophages. Yao Xue Xue Bao 2001;36:161-164.
    • (2001) Yao Xue Xue Bao , vol.36 , pp. 161-164
    • Hu, Y.F.1    Guo, Y.2    Cheng, G.F.3
  • 75
    • 0042884177 scopus 로고    scopus 로고
    • Inhibitory effect of meloxicam on human polymorphonuclear leukocyte adhesion to human synovial cell
    • Li LC, Hou Q, Guo Y, et al. Inhibitory effect of meloxicam on human polymorphonuclear leukocyte adhesion to human synovial cell. Yao Xue Xue Bao 2002;37:103-107.
    • (2002) Yao Xue Xue Bao , vol.37 , pp. 103-107
    • Li, L.C.1    Hou, Q.2    Guo, Y.3
  • 76
    • 0037334544 scopus 로고    scopus 로고
    • Selective inhibitors of cyclooxygenase-2 delay the activation of nuclear factor KB and attenuate the expression of inflammatory genes in murine macrophages treated with lipopolysaccharide
    • Callejas NA, Fernandez-Martinez A, Castrillo A, et al. Selective inhibitors of cyclooxygenase-2 delay the activation of nuclear factor KB and attenuate the expression of inflammatory genes in murine macrophages treated with lipopolysaccharide. Mol Pharmacol 2003;63:671-677.
    • (2003) Mol Pharmacol , vol.63 , pp. 671-677
    • Callejas, N.A.1    Fernandez-Martinez, A.2    Castrillo, A.3
  • 77
    • 4644289081 scopus 로고    scopus 로고
    • Anti-inflammatory drugs and tumor necrosis factor-α production from monocytes: Role of transcription factor NFκB and implication for rheumatoid arthritis therapy
    • Lavagno L, Gunella G, Bardelli C, et al. Anti-inflammatory drugs and tumor necrosis factor-α production from monocytes: Role of transcription factor NFκB and implication for rheumatoid arthritis therapy. Eur J Pharm 2004;501:199-208.
    • (2004) Eur J Pharm , vol.501 , pp. 199-208
    • Lavagno, L.1    Gunella, G.2    Bardelli, C.3
  • 78
    • 11244334168 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation
    • Takada Y, Bhardwaj A, Potdar P, et al. Nonsteroidal antiinflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. Oncogene 2004;23:9247-9258.
    • (2004) Oncogene , vol.23 , pp. 9247-9258
    • Takada, Y.1    Bhardwaj, A.2    Potdar, P.3
  • 79
    • 0035914407 scopus 로고    scopus 로고
    • Positive and negative regulation of NF-κB by COX-2. Roles of different prostaglandins
    • Poligone B, Baldwin AS. Positive and negative regulation of NF-κB by COX-2. Roles of different prostaglandins. J Biol Chem 2001;276:38658-38664.
    • (2001) J Biol Chem , vol.276 , pp. 38658-38664
    • Poligone, B.1    Baldwin, A.S.2
  • 80
    • 0035403764 scopus 로고    scopus 로고
    • Celecoxib loses its anti-inflammatory efficacy at high doses through activation of NFκB
    • Niederberger E, Tegeder I, Vetter G, et al. Celecoxib loses its anti-inflammatory efficacy at high doses through activation of NFκB. FASEB J 2001;15:1622-1824.
    • (2001) FASEB J , vol.15 , pp. 1622-1824
    • Niederberger, E.1    Tegeder, I.2    Vetter, G.3
  • 81
    • 0036156738 scopus 로고    scopus 로고
    • Absence of nuclear factor KB inhibition by NSAIDs in hepatocytes
    • Callejas NA, Casado M, Bosca L, et al. Absence of nuclear factor KB inhibition by NSAIDs in hepatocytes. Hepatology 2002;35:341-348.
    • (2002) Hepatology , vol.35 , pp. 341-348
    • Callejas, N.A.1    Casado, M.2    Bosca, L.3
  • 82
    • 29644435432 scopus 로고    scopus 로고
    • Lipopolysaccharide induces cyclooxygenase-2 in intestinal epithelium via a noncanonical p38 MAPK pathway
    • Grishin AV, Wang J, Potoka DA, et al. Lipopolysaccharide induces cyclooxygenase-2 in intestinal epithelium via a noncanonical p38 MAPK pathway. J Immunol 2006;176:580-588.
    • (2006) J Immunol , vol.176 , pp. 580-588
    • Grishin, A.V.1    Wang, J.2    Potoka, D.A.3
  • 83
    • 0036959446 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinases and their relationship with NF-κB and PPARγ in indomethacin-induced apoptosis of colon cancer cells
    • Kim TI, Jin SH, Kang EH, et al. The role of mitogen-activated protein kinases and their relationship with NF-κB and PPARγ in indomethacin-induced apoptosis of colon cancer cells. Ann NY Acad Sci 2002;973:241-245.
    • (2002) Ann NY Acad Sci , vol.973 , pp. 241-245
    • Kim, T.I.1    Jin, S.H.2    Kang, E.H.3
  • 84
    • 2642546700 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases regulate COX-2 and mucosal recovery in ischemic-injured porcine ileum
    • Shifflett DE, Jones SL, Moeser AJ, et al. Mitogen-activated protein kinases regulate COX-2 and mucosal recovery in ischemic-injured porcine ileum. Am J Physiol Gastrointest Liver Physiol 2004;286:G906-G913.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286
    • Shifflett, D.E.1    Jones, S.L.2    Moeser, A.J.3
  • 85
    • 25644435619 scopus 로고    scopus 로고
    • Naito Y, Mizushima K, Yoshikawa T. Global analysis of gene expression in gastric ischemia-reperfusion: A future therapeutic direction for mucosal protective drugs. Dig Dis Sci 2005;50Suppl 1:S45-55.
    • Naito Y, Mizushima K, Yoshikawa T. Global analysis of gene expression in gastric ischemia-reperfusion: A future therapeutic direction for mucosal protective drugs. Dig Dis Sci 2005;50Suppl 1:S45-55.
  • 86
    • 0036086261 scopus 로고    scopus 로고
    • Indomethacin lowers the threshold thermal exposure for hyperthermic radio-sensitization and heat-shock inhibition of ionizing radiation-induced activation of NF-kappaB
    • Locke JE, Bradbury CM, Wei SJ, et al. Indomethacin lowers the threshold thermal exposure for hyperthermic radio-sensitization and heat-shock inhibition of ionizing radiation-induced activation of NF-kappaB. Int J Radiat Biol 2002;78:493-502.
    • (2002) Int J Radiat Biol , vol.78 , pp. 493-502
    • Locke, J.E.1    Bradbury, C.M.2    Wei, S.J.3
  • 87
    • 0346728756 scopus 로고    scopus 로고
    • Indomethacin and ibuprofen induce Hsc70 nuclear localization and activation of the heat shock response in HeLa cells
    • Lagunas L, Bradbury CM, Laszlo A, et al. Indomethacin and ibuprofen induce Hsc70 nuclear localization and activation of the heat shock response in HeLa cells. Biochem Biophys Res Commun 2004;313:863-870.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 863-870
    • Lagunas, L.1    Bradbury, C.M.2    Laszlo, A.3
  • 88
    • 0032949624 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines that induce HSP70 in human monocytes
    • Nousby JN, Cahil CM, Chu B, et al. Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines that induce HSP70 in human monocytes. Cytokine 1999;11:347-358.
    • (1999) Cytokine , vol.11 , pp. 347-358
    • Nousby, J.N.1    Cahil, C.M.2    Chu, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.