Aspirin, but not the more selective cyclooxygenase (COX)-2 inhibitors meloxicam and SC 58125, aggravates postischaemic cardiac dysfunction, independent of COX function

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 363, Issue 2, 2001, Pages 233-240

  Heindl, B ^a   Becker, B F ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Acetylsalicylic acid; Heart; Ischaemia; Meloxicam; Oxidative phosphorylation; Prostaglandins; Reperfusion

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; 8 ISOPROSTAGLANDIN F2 ALPHA; ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CYCLOOXYGENASE 2 INHIBITOR; ISOPROSTANE DERIVATIVE; LACTIC ACID; MELOXICAM; PROSTACYCLIN; PYRUVIC ACID; THROMBOXANE A2;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; ENZYME INHIBITION; GUINEA PIG; HEART EJECTION FRACTION; HEART FUNCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART RATE; HYPEREMIA; MALE; NONHUMAN; OXIDATIVE PHOSPHORYLATION;

ANIMALS; ASPIRIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROST; EICOSANOIDS; F2-ISOPROSTANES; GUINEA PIGS; HEART; HEMODYNAMIC PROCESSES; ISOENZYMES; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; THIAZINES; THIAZOLES; THROMBOXANE A2;

EID: 0035092246     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100000349     Document Type: Article

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