Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: Evidence for intron 1 retention

Journal of Pharmacology and Experimental Therapeutics

Volumn 315, Issue 3, 2005, Pages 1298-1305

  Qin, Ning ^a   Zhang, Sui Po ^a   Reitz, Tasha L ^a   Mei, Jay M ^a   Flores, Christopher M ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMINOPHENAZONE; ARACHIDONIC ACID; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 B1; CYCLOOXYGENASE 1 B2; CYCLOOXYGENASE 1 B3; CYCLOOXYGENASE 3; DICLOFENAC; DIPYRONE; IBUPROFEN; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; NUCLEOTIDE; PARACETAMOL; PHENACETIN; PHENAZONE; PROSTAGLANDIN F2 ALPHA; ROFECOXIB; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; FRAMESHIFT MUTATION; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRON; MOLECULAR BIOLOGY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN CONTENT; PROTEIN FUNCTION; RNA SPLICING; STATISTICAL SIGNIFICANCE;

ACETAMINOPHEN; AMINO ACID SEQUENCE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BASE SEQUENCE; BLOTTING, WESTERN; CLONING, MOLECULAR; CYCLOOXYGENASE 1; GENE EXPRESSION; HUMANS; INSECTS; INTRONS; ISOENZYMES; KINETICS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; RNA SPLICING; RNA, MESSENGER; SPODOPTERA; TISSUE DISTRIBUTION; VARIATION (GENETICS);

EID: 27744529775     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.090944     Document Type: Article

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