Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo

Gene Therapy

Volumn 11, Issue 10, 2004, Pages 856-864

  Chen, Z Y ^a   He, C Y ^a   Meuse, L ^a   Kay, M A ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bacterial backbone; Expression cassette; Human 1 antitrypsin; Human factor IX; Linearized DNA; Transcriptional silencing

Indexed keywords

BACTERIAL DNA; COMPLEMENTARY DNA; PLASMID DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA BINDING; DNA MODIFICATION; DNA PURIFICATION; DNA STRUCTURE; EPISOME; GENE CASSETTE; GENE EXPRESSION PROFILING; GENE SILENCING; GENE VECTOR; IN VIVO STUDY; LIVER; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; TRANSGENE;

ALPHA 1-ANTITRYPSIN; ANIMALS; DNA, BACTERIAL; ENHANCER ELEMENTS (GENETICS); FACTOR IX; GENE EXPRESSION PROFILING; GENE SILENCING; GENETIC VECTORS; HUMANS; LIVER; MICE; MICE, INBRED C57BL; PLASMIDS; PROMOTER REGIONS (GENETICS); TRANSGENES;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 2642519089     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302231     Document Type: Article

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