Alkyl-CoA Disulfides as Inhibitors and Mechanistic Probes for FabH Enzymes

Chemistry and Biology

Volumn 14, Issue 5, 2007, Pages 513-524

  Alhamadsheh, Mamoun M ^a   Musayev, Faik ^b   Komissarov, Andrey A ^a   Sachdeva, Sarbjot ^a,b   Wright, H Tonie ^b   Scarsdale, Neel ^b   Florova, Galina ^a   Reynolds, Kevin A ^a  

^a PORTLAND STATE UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

CHEMBIOL

Indexed keywords

3 KETOACYL ACYL CARRIER PROTEIN SYNTHASE III; 3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; 3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III; CYSTEINE; DISULFIDE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; ESCHERICHIA COLI; FLUORESCENCE; FLUOROMETRY; KINETICS; STREPTOMYCES; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE; ACYLATION; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DISULFIDES; ENZYME INHIBITORS; ESCHERICHIA COLI; FLUORESCENCE; FLUOROMETRY; INDICATORS AND REAGENTS; KINETICS; MODELS, MOLECULAR; STREPTOMYCES;

ESCHERICHIA COLI; MYCOBACTERIUM TUBERCULOSIS;

EID: 34248563049     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2007.03.013     Document Type: Article

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