(S)-armepavine inhibits human peripheral blood mononuclear cell activation by regulating Itk and PLCγ activation in a PI-3K-dependent manner

Journal of Leukocyte Biology

Volumn 81, Issue 5, 2007, Pages 1276-1286

  Liu, Chih Peng ^a   Kuo, Yuh Chi ^b   Shen, Chien Chang ^c,d   Wu, Ming Hsi ^a   Liao, Jyh Fei ^a   Lin, Yun Lian ^c,d   Chen, Chieh Fu ^a,e   Tsai, Wei Jern ^a,c,d  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^c NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^d National Tai Tung University   (Taiwan)

^e QINGDAO UNIVERSITY   (China)

Author keywords

Cytokines; Lymphocytes; Phytohemagglutinin; Proliferation

Indexed keywords

ARMEPAVINE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; PHOSPHOLIPASE C GAMMA; PHYTOHEMAGGLUTININ; PROTEIN C FOS; PROTEIN KINASE C; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70; TRANSCRIPTION FACTOR NFAT;

ARTICLE; CALCIUM MOBILIZATION; CELL ACTIVATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG INHIBITION; DRUG STRUCTURE; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALKALOIDS; BENZYLISOQUINOLINES; CALCIMYCIN; CALCIUM; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTERFERON TYPE II; INTERLEUKIN-2; LEUKOCYTES, MONONUCLEAR; MOLECULAR CONFORMATION; MOLECULAR WEIGHT; NELUMBO; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN-TYROSINE KINASES; RNA, MESSENGER; SEEDS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRADECANOYLPHORBOL ACETATE;

MUS; NELUMBO NUCIFERA;

EID: 34247885828     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0106056     Document Type: Article

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