Autocrine production of IFN-γ by macrophages controls their recruitment to kidney and the development of glomerulonephritis in MRL/lpr mice

Journal of Immunology

Volumn 169, Issue 2, 2002, Pages 1058-1067

  Carvalho Pinto, Carla E ^a   García, María I ^a   Mellado, Mario ^a   Rodríguez Frade, J Miguel ^a   Martín Caballero, Juan ^a   Flores, Juana ^a   Martínez A, Carlos ^a   Balomenos, Dimitrios ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CELL ADHESION MOLECULE; DNA ANTIBODY; GAMMA INTERFERON; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; AUTOCRINE EFFECT; AUTOIMMUNE DISEASE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GLOMERULONEPHRITIS; INFLAMMATION; KIDNEY; LUPUS ERYTHEMATOSUS; MACROPHAGE; MACROPHAGE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0037100297     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.2.1058     Document Type: Article

References (35)

1. Uncoupling of complex formation and kidney damage in autoimmune glomerulonephritis
2. Interferon-γ is required for lupus-like disease and lymphoaccumulation
3. Monocyte chemoattractant protein 1-dependent leukocytic infiltrates are responsible for autoimmune disease in MRL-Fas lpr mice
4. Immune response in mice that lack the interferon-γ receptor
5. Multiple defects of immune cell function in mice with disrupted interferon-γ genes
6. In vivo cytokine gene expression in T cell subsets of the autoimmune MRL-lpr/lpr mouse
7. Quantitative polymerase chain reaction analysis reveals marked overexpression of interleukin1β, interleukin-10, and interferon-γ mRNA in the lymph nodes of lupus-prone mice
8. 1 lupus-like nephritis with monoclonal antibody to γ interferon
9. Experimental therapy of systemic lupus erythematosus: The treatment of NZB/W mice with mouse soluble interferon-γ receptor inhibits the onset of glomerulonephritis
10. Roles of interferon-γ and interleukin-4 murine lupus
11. 1 mice
12. IFN-γ is essential for the development of autoimmune glomerulonephritis in MRL/lpr mice
13. IFN-γ receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas lpr mice
14. Interferon-γ (IFN-γ) is necessary for the genesis of acetylcholine receptor-induced clinical experimental autoimmune myasthenia gravis in mice
15. Treatment of murine lupus with cDNA encoding IFN-γR/Fc
16. Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice
17. Characterization of the CCR2 chemokine receptor: Functional CCR2 receptor expression in B cells
18. Renal expression of monocyte chemoattractant protein-1 in lupus autoimmune mice
19. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant
20. Monocyte chemoattractant protein-1 promotes macrophage-mediated tubular injury, but not glomerular injury, in nephrotoxic serum nephritis
21. Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
22. Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice
23. Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
24. Cell adhesion molecules and inflammatory renal diseases
25. IL-12 drives IFN-γ dependent autoimmune kidney disease in MRL-Fas lpr mice
26. The chemokine system: Redundancy for robust outputs
27. Control of Th2 polarization by the chemokine monocyte chemoattractant protein-1
28. Localization of Th-cell subsets in inflammation: Differential thresholds for extravasation of Th1 and Th2 cells
29. Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells
30. Cell adhesion molecule expression in murine lupus-like nephritis induced by lipopolysaccharide
31. Induction of RANTES, HLA-DR, and intercellular adhesion molecule-1 on highly purified distal tubular cells from human kidney
32. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury
33. Intercellular adhesion molecular-deficiency prolongs survival and protects against the development of pulmonary inflammation during murine lupus
34. Intercellular adhesion molecule-1 deficiency protects MRL/MpJ-Fas lpr mice from early lethality
35. Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor