Armepavine oxalate induces cell death on CCRF-CEM leukemia cell line through an apoptotic pathway

Life Sciences

Volumn 75, Issue 5, 2004, Pages 549-557

  Jow, Guey Mei ^a   Wu, Yang Chang ^b   Guh, Jih Hwa ^c   Teng, Che Ming ^c  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b Grad Institute of Natural Products   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Armepavine oxalate; Bcl 2; CCRF CEM leukemia cell

Indexed keywords

ANTINEOPLASTIC AGENT; ARMEPAVINE; ARMEPAVINE OXALATE; ATHEROSPERMINE N OXIDE; CASPASE 3; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKEMIA; NITROBLUE TETRAZOLIUM TEST; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; SURVIVAL RATE; WESTERN BLOTTING;

EID: 2442644929     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2003.12.017     Document Type: Article

References (27)

1. Anto R.J., Mukhopadhyay A., Denning K., Aggarwal B.B. Curcumin (Diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis. 23:2002;143-150
2. Budd R.C. Activation-induced cell death. Current Opinion in Immunology. 13:2001;356-362
3. Calixto J.B., Santos A.R., Cechinel F.V., Yunes K.A. A review of the plants of the genus Phyllanthus: their chemistry, pharmacology, and therapeutic potential. Medical Research Reviews. 18:1998;225-258
4. Chen K.S., Ko F.N., Teng C.M., Wu Y.C. Antiplatelet and vasorelaxing actions of some benzylisoquinolone and phenanthrene alkaloids. Journal of National Production. 59:1996;531-534
5. Cory S., Vaux D.L., Strasser A., Harris A.W., Adams J.M. Insights from Bcl-2 and Myc: malignancy involves abrogation of apoptosis as well as sustained proliferation. Cancer Research. 59:1999;1685s-1692s
6. Dales J.P., Palmerini F., Devilard E., Hassoun J., Birg F., Xerri L. Caspases: conductors of the cell death machinery in lymphoma cells. Leukemia and Lymphoma. 41:2001;247-253
7. Evan G., Littlewood T. A matter of life and cell death. Science. 281:1998;1317-1322
8. Fanidi A., Harrington E.A., Evan G.I. Cooperative interaction between c-myc and proto-oncongenes. Nature. 359:1992;554-556
9. Green D.R. Apoptotic pathways: the roads to ruin. Cell. 94:1998;695-698
10. Gross A., McDonnel J.M., Korsmeyer S.J. Bcl-2 family members and the mitochondria in apoptosis. Genes Development. 13:1999;1899-1911
11. Huang A. Bcl-2 family proteins as targets for anticancer drug design. Oncogene. 19:2002;6627-6631
12. Kluck R.M., Bossy Wetzel E., Green D.R., Newmeyer D.D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science. 275:1997;1132-1136
13. Lin C.H., Ko F.N., Wu Y.C., Lu S.T., Teng C.M. The relaxant actions on quinea-pig trachelis of atherosperminine isolated from Fissistigma Glaucescens. European Journal of Pharmacology. 237:1993;109-116
14. Lu S.T., Wu Y.C., Leou S.P. Alkaloids of Formosan Fissistigma and Goniothalamus species. Phytochemistry. 24:1985;1829-1835
15. Marsden V.S., O'Connor L., O'Reilly L.A., Silke J., Metcalf D., Ekert P.G., Huang D.C.S., Cecconi F., Kuida K., Tomaselli K.J., Roy S., Nicholson D.W., Vaux D.L., Bouillet P., Adams J.M., Strasser A. Apoptosis initiated by Bcl-2 regulated caspase activation independently of the cytochrome c/Apaf-1/Caspase-9 apoptosome. Nature. 419:2002;634-637
16. Mosmann T. Rapid colorimetric assay for cell growth and survival application to proliferation and cytotoxic assays. Journal of Immunology Methods. 65:1983;55-63
17. Murph A.N., Bredesen D.N., Cortopassi G., Wang E., Fiskum G. Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proceeding National Academic Science. 93:1996;9893-9898
18. Reed J.C. Bcl-2 family protein. Oncogene. 17:1998;3225-3236
19. Sarast A., Pulkki K. Morphologic and biochemical hallmarks of apoptosis. Cardiovascular Research. 45:2000;528-537
20. Shimizu S., Narita M., Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature. 399:1999;483-487
21. Strasser A., O'Connor L., Dixit V.M. Apoptosis signaling. Annual Review of Biochemistry. 69:2000;17-45
22. Sun X.M., MacFarlane M., Zhuang J., Wolf B.B., Green D.R., Cohen G.M. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. Journal Biological Chemistry. 274:1999;5053-5060
23. Thompson C.B. Apoptosis in the pathogenesis and treatment of disease. Science. 267:1995;1456-1462
24. Thornberry N.A., Lazebnik Y. Caspases: enemies within. Science. 281:1998;1312-1316
25. Vergote D., Cren-Olive C., Chopin V., Toillon R.A., Rolando R., Hondermarck H., Bourhis X. (-)-Epigallocatechin (EGC) of green tea induces apoptosis of human breast cancer cells but not of their normal counterparts. Breast cancer Research and Treatment. 76:2002;195-201
26. Wyllie A.H. Apoptosis. Brtish Journal of Cancer. 67:1993;205-208
27. Yang J., Liu X., Bhala K., Kim C.N., Ibrado A.M., Cai J., Peng T.I., Jones D.P., Wang X. Prevention of apoptosis by Bcl-2; release of cytochrome c from mitochondria blocked. Science. 275:1997;1129-1132