B cell conducts the lymphocyte orchestra

Journal of Autoimmunity

Volumn 28, Issue 2-3, 2007, Pages 143-151

  Youinou, Pierre ^a  

^a BREST UNIVERSITY HOSPITAL   (France)

Author keywords

Autoimmune disease; B lymphocyte; B cell antigen receptor; CD5; Dendritic cell

Indexed keywords

B LYMPHOCYTE ANTIGEN; CD5 ANTIGEN; CYTOKINE; INTERLEUKIN 10; LYMPHOTOXIN; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN PRESENTING CELL; AUTOIMMUNE DISEASE; AUTOIMMUNITY; B LYMPHOCYTE ACTIVATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CELL SELECTION; CELL SUBPOPULATION; DENDRITIC CELL; GENE MUTATION; GENETIC REGULATION; HUMAN; LIPID RAFT; LYMPHOCYTE; ONTOGENY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; AUTOIMMUNE DISEASES; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; CYTOKINES; HUMANS; IMMUNE TOLERANCE; LYMPHOCYTE ACTIVATION; MICE; MICE, SCID; RECEPTORS, ANTIGEN, B-CELL; T-LYMPHOCYTES;

EID: 34247587010     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2007.02.011     Document Type: Review

References (77)

1. Hoffman R.W. T cells in the pathogenesis of systemic lupus erythematosus. Front Biosci 6 (2001) 1369-1378
2. In: Peter J.B., and Shoenfeld Y. (Eds). Autoantibodies (1996), Elsevier Science, Amsterdam p. 880
3. Tomer Y., Buskila D., and Shoenfeld Y. Pathogenic significance and diagnostic value of lupus autoantibodies. Int Arch Allergy Immunol 100 (1993) 293-306
4. Lipsky P.E. Systemic lupus erythematosus: an autoimmune disease of B-cell hyperactivity. Nat Immunol 2 (2001) 764-766
5. Davidson A., and Diamond B. Autoimmune diseases. N Engl J Med 345 (2001) 340-350
6. Klinman D.M., and Steinberg A.D. Systemic autoimmune diseases arise from polyclonal B-cell activation. J Exp Med 165 (1987) 1755-1760
7. Youinou P., Sémana G., Muller S., Piette J.C., Guillevin L., Jouquan J., et al. Interaction between HLA class II determinants and TCR β elements promote the antibody production to extractable nuclear antigen-related peptides. Hum Immunol 52 (1997) 12-21
8. Youinou P., Le Goff P., Merdrignac G., Tuaillon N., Lamour A., MacKenzie L.E., et al. The relation between CD5-B lymphocytes in rheumatoid arthritis patients and their relatives. Arthritis Rheum 33 (1990) 339-348
9. Reveille J.D., Wilson R.W., Provost T.T., Bias W.B., and Arnett F.C. Primary Sjögren's syndrome and other autoimmune diseases in families. Prevalence and immunogenetic studies in six kindreds. Ann Intern Med 101 (1984) 748-756
10. Looney R.J. Treating human autoimmune disease by depleting B cells. Ann Rheum Dis 61 (2002) 863-866
11. Caligaris-Cappio F., Gobbi M., Bofill M., and Janossy G. Infrequent normal B lymphocytes express features of B chronic lymphocytic leukemia. J Exp Med 155 (1982) 623-628
12. Youinou P., MacKenzie L.E., Le Masson G., Papadopoulos N.M., Jouquan J., Pennec Y.L., et al. CD5-expressing B lymphocytes in the blood and salivary glands of patients with primary Sjögren's syndrome. J Autoimm 1 (1988) 185-194
13. Lydyard P.M., MacKenzie L.E., Youinou P., Deane M., Jefferis R., and Mageed R.A. Specificity and idiotype expression of IgM produced by CD5+ and CD5- cord blood B cells. Ann NY Acad Sci 651 (1992) 527-535
14. Youinou P, MacKenzie L, Lamour A, Mageed RA, Lydyard PM. Human CD5-positive B cells in lymphoid malignancy and connective tissue disease. Eur J Clin Invest 1993;23:139-50.
15. Bröker B.M., Klajman A., Youinou P., Jouquan J., Worman C.P., Murphy J., et al. Chronic lymphocytic leukemia cells secrete multispecific autoantibodies. J Autoimmun 1 (1988) 469-481
16. Youinou P., and Lydyard P.M. CD5+ B cells in nonorgan-specific autoimmune diseases: a fresh look. Lupus 10 (2001) 523-525
17. Wortis H.H., and Berland R. Cutting edge commentary: origins of B-1 cells. J Immunol 166 (2001) 2163-2166
18. Herzenberg L.A. B-1 cells: the lineage question revisited. Immunol Rev 175 (2000) 9-19
19. Montecino-Rodriguez E., Leathers H., and Dorshkind K. Identification of a B-1 B cell-specified progenitor. Nat Immunol 7 (2006) 293-301
20. Kantor A. A new nomenclature for B cells. Immunol Today 12 (1991) 388-391
21. Youinou P., Jamin C., and Lydyard P.M. CD5 expression in human B-cell populations. Immunol Today 20 (1999) 312-316
22. Kassian M.T., Ikematsu H., and Casali P. Identification and analysis of a novel surface CD5-B lymphocyte subset producing natural antibodies. J Immunol 148 (1992) 2690-2702
23. Pers J.O., Jamin C., Lydyard P.M., Charreire J., and Youinou P. The H2 haplotype regulates the distribution of B cells into B1a, B1b and B2 subsets. Immunogenetics 54 (2002) 208-211
24. Pers J.O., Jamin C., Youinou P., and Charreire J. Role of IL-10 in the distribution of B-cell subsets in the mouse B1 cell population. Eur Cytokine Netw 14 (2003) 178-185
25. Anaya J.M., Correa P.A., Herrera M., Eskdale J., and Gallaghes G. Interleukin 10 (IL-10) influences autoimmune response in primary Sjögren's syndrome and is linked to IL-10 gene polymorphism. J Rheumatol 29 (2002) 1874-1876
26. Paavonen T, Quartey-Papafio R, Delves PJ, MacKenzie LE, Lund T, Youinou P, et al. CD5 mRNA expression and autoantibody production in early human B cells immortalized by EBV. Scand J Immunol 31: 369-74.
27. Carsetti R., Kohler G., and Lamers M.C. Transitional B cells are the target of negative selection in the B-cell compartment. J Exp Med 181 (1995) 2129-2140
28. Sims G.P., Ettinger R., Shirota Y., Yarboro C.H., Illei G.G., and Lipsky P.E. Identification and characterization of circulating human transitional B cells. Blood 105 (2005) 4390-4398
29. Camacho S.A., Kosco-Vilbois M.H., and Berek C. The dynamic structure of the germinal center. Immunol Today 19 (1998) 511-514
30. Martin F., and Kearney J.F. Marginal-zone B cells. Nat Rev Immunol 2 (2002) 323-335
31. Liu Y.J., and Arpinc C. Germinal center development. Immunol Rev 156 (1997) 111-126
32. Groom J., Kalled S.L., Cutler A.H., Olson C., Woodcock S.A., Schneider P., et al. Association of BAFF/BLyS overexpression and altered B-cell differentiation with Sjögren's syndrome. J Clin Invest 109 (2002) 59-68
33. William J., Euler C., Christensen S., and Shlomchik M.J. Evolution of autoantibody responses via somatic hypermutation outside the germinal centers. Science 297 (2002) 2066-2070
34. Grammer A.C., and Lipsky P.E. CD40-mediated regulation of immune responses by TRAF-dependent and TRAF-independent signaling mechanisms. Adv Immunol 76 (2001) 61-178
35. Grammer A.C., and Lipsky P.E. CD154-CD40 interactions mediate differentiation to plasma cells in healthy individuals and persons with systemic lupus erythematosus. Arthritis Rheum 46 (2002) 1417-1429
36. d'Arbonneau F., Pers J.O., Devauchelle V., Pennec Y., Saraux A., and Youinou P. BAFF-induced changes in B-cell antigen receptor-containing lipid rafts in Sjogren's syndrome. Arthritis Rheum 54 (2006) 115-126
37. Bohnkorst J., Bjørgan M.B., Thoen J.E., Natvig J.B., and Thompson K.M. Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B-cell subpopulations in patients with primary Sjögren's syndrome. J Immunol 167 (2001) 3610-3618
38. Hansen A., Odenhahl M., Le Reiter K., Jacobi A.M., Feist E., Scholze J., et al. Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjögren's syndrome. Arthritis Rheum 46 (2002) 12160-12171
39. Odendahl M., Jacobi A., Hansen A., Feist E., Hiepe F., Burmester G.R., et al. Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. J Immunol 165 (2000) 5970-5979
40. Reparon-Schuijt C., van Esch W.E.J., van Kooten C., Ezendan N.P.M., Levarht E.W.N., Breedveld F.C., et al. Presence of a population of CD20+ CD38- lymphocytes with defective proliferative responsiveness in the synovial compartment of patients with rheumatoid arthritis. Arthritis Rheum 44 (2001) 2029-2037
41. Reininger L., Winkler T.H., Kalberer C.P., Jourdain M., Melchers F., and Rolink A.G. Intrinsic B-cell defects in NZB and NZW mice contribute to systemic lupus erythematosus in (NZBXNZW) F1 mice. J Exp Med 184 (1996) 853-861
42. Chan O.T.M., Hannum L.G., Haberman A.M., Madaio M.P., and Shlomchik M.J. A novel mouse with B cells but lacking serum antibody reveals an antibody-dependent role for B cells in murine lupus. J Exp Med 189 (1999) 1639-1648
43. Pasparakis M., Alexopoulou L., Episkopou V., and Kollias G. Immune and inflammatory responses in TNF-α-deficient mice: a critical recruitment for TNF-α in the formation of primary B-cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J Exp Med 184 (1998) 1397-1411
44. Flynn S., Toellner K.M., Raykundalia C., Goodall M., and Lane P. CD4 T cell cytokine differentiation: the B-cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin-4 and upregulates expression of the chemokine receptor Bbr-1. J Exp Med 188 (1998) 297-304
45. Schultz K.R., Klarnet J.P., Gieni R.S., HayGlass K.T., and Greenberg P.D. The role of B cells for in vivo T cell response to a Friend virus-induced leukemia. Science 249 (1990) 921-923
46. Mohan C., Morel L., Yang P., and Wakeland E.K. Accumulation of splenic B-1a cell with potent antigen-presenting capability in NZM2410 lupus-prone mice. Arthritis Rheum 41 (1998) 1652-1662
47. Takemura S., Klimiuk P.A., Braun A., Coronzy J.J., and Weyand C.M. T cell activation in rheumatoid synovium in B cell-dependent. J Immunol 167 (2001) 4710-4718
48. Dustin M.L., and Dustin L.B. The immunological relay race: B cells take antigen by synapse. Nat Immunol 2 (2001) 480-482
49. Nagafuchi H., Suzuki N., Mizushima Y., and Sakane T. Constitutive expression of IL-6 receptors and their role in the excessive B-cell function in patients with systemic lupus erythematosus. J Immunol 151 (1993) 6525-6534
50. Moore K.W., de Waal Malefyt R., Coffman R.L., and O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 19 (2001) 683-765
51. Harris D.P., Haynes L., Sayles P.C., Duso D.K., Eaton S.M., Lepak N.M., et al. Reciprocal regulation of polarized cytokine production by effector B and T cells. Nat Immunol 1 (2000) 475-482
52. Youinou P., Daridon C., Saraux A., Devauchelle V., and Pers J.O. Is B-cell the conductor of the lymphocyte orchestra in the salivary glands of patients with primary Sjögren's syndrome?. Clin Exp Rheumatol (24)5 (2006) 491-492
53. Mtsuchi L., and Gold M.R. New views of BCR structure and organization. Curr Opin Immunol 13 (2001) 270-277
54. Healy J.I., and Goodnow C.C. Positive versus negative signalling by lymphocyte antigen receptors. Annu Rev Immunol 16 (1998) 645-670
55. Lam K.P., Hühn R., and Rajewsky R. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90 (1997) 1073-1083
56. Renaudineau Y., Nédellec S., Berthou C., Lydyard P.M., Youinou P., and Pers J.O. Role of B-cell antigen receptor associated molecules and lipid rafts in CD5-induced apoptosis of B CLL cells. Leukemia 19 (2005) 223-229
57. Nédellec S., Renaudineau Y., Berthou C., Bordron A., Porakishvili N., Lydyard P.M., et al. B-cell response surface IgM cross-linking identifies different prognostic groups of B-chronic lymphocytic leukemia patients. J Immunol 174 (2005) 3749-3756
58. Liossis S.M.C., Kovacs B., Dennis G., and Kammer G.C. B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early transduction events. J Clin Invest 98 (1996) 2549-2557
59. Casciola-Rosen L.A., Anhalt G., and Rosen A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic kératinocytes. J Exp Med 179 (1994) 1317-1330
60. Pers J.O., Jamin C., Le Corre R., Lydyard P.M., and Youinou P. Ligation of CD5 on resting B cells, but not on resting T cells, results in apoptosis. Eur J Immunol 28 (1998) 4170-4176
61. Jamin C., Le Corre R., Lydyard P.M., and Youinou P. Anti-CD5 extends the proliferative response of human CD5+ B cells activated with anti-IgM and interleukin-2. Eur J Immunol 26 (1996) 57-62
62. Huck S., Le Corre R., Youinou P., and Zouali M. Expression of B-cell receptor-associated signaling molecules in human lupus. Autoimmunity 33 (2001) 213-224
63. Inaoki M., Sato S., Weintraub B.C., Goodnow C.C., and Tedder T.F. CD19-regula-ted signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. J Exp Med 186 (1997) 1923-1931
64. Sato S., Hasegawa M., Fujimoto M., Tedder T.F., and Takehara K. Quantitative genetic variation in CD19 expression correlates with autoimmunity. Immunol 165 (2000) 6635-6643
65. Hippen K.L., Tze L.E., and Behrens T.W. CD5 maintains tolerance in anergic B cells. J Exp Med 191 (2000) 883-889
66. Tiegs S.L., Russel D.M., and Nemazee D. Receptor editing in self-reactive bone marrow B cells. J Exp Med 177 (1993) 1009-1020
67. Hillion S., Saraux A., Youinou P., and Jamin C. Expression of RAGs in peripheral B cells outside germinal centers is associated with the expression of CD5. J Immunol 174 (2005) 5553-5561
68. Pierce S.K. Lipid rafts and B-cell activation. Nat Rev Immunol 2 (2002) 96-105
69. Cherukuri A., Cheng P.C., Sohn H.W., and Pierce S.K. The CD19/CD21 complex functions to prolong B-cell antigen receptor signaling from lipid rafts. Immunity 14 (2001) 169-179
70. Aman M.J., Tosello-Trampont A.C., and Ravichandran K. Fcγ RII B1/SHIP-mediated inhibitory signaling in B cells involves lipid rafts. J Biol Chem 276 (2001) 46371-46378
71. Mackay F., and Browning J.L. BAFF: a fundamental survival factor for B cells. Nat Rev Immunol 2 (2002) 465-475
72. Pers J.O., Daridon C., Devauchelle V., Jousse S., Saraux A., Jamin C., et al. BAFF overexpression is associated with autoantibody production in autoimmune diseases. Ann NY Acad Sci 1050 (2005) 34-39
73. Szodaray P., Jellestad S., Ohlsson Teague M., and Jonsson R. Attenuated apoptosis of B-cell activating factor-expressing cells in primary Sjögren's syndrome. Lab Invest 83 (2003) 357-365
74. Daridon C, Youinou P, Pers JO. BAFF, APRIL, TWE-PRIL: who's who? Autoimmun Rev, in press.
75. Jamin C., Magadur G., Lamour A., MacKenzie L., Lydyard P.M., Katsikis P.D., et al. Cell-free CD5 in patients with rheumatic diseases. Immunol Lett 31 (1991) 79-84
76. Renaudineau Y., Hillion S., Saraux A., Mageed R.A., and Youinou P. An alternative exon 1 of the CD5 gene regulates CD5 expression in human B lymphocytes. Blood 106 (2005) 2781-2789
77. Edwards J.C., and Cambridge G. B-cell targeting in rheumatoid arthritis and other autoimmune diseases. Nat Rev Immunol 6 (2006) 394-403