New views of BCR structure and organization

Current Opinion in Immunology

Volumn 13, Issue 3, 2001, Pages 270-277

  Matsuuchi, Linda ^a   Gold, Michael R ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; B LYMPHOCYTE RECEPTOR; LIPID; RECEPTOR SUBUNIT;

ANTIGEN BINDING; B LYMPHOCYTE; ENZYME LOCALIZATION; KAPOSI SARCOMA; LYMPHOCYTE FUNCTION; LYMPHOMA; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; STOICHIOMETRY;

EID: 0035367946     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(00)00215-6     Document Type: Review

References (34)

1. The Igα/Igβ heterodimer on μ-negative proB cells is competent for transducing signals to induce early B cell differentiation
2. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
3. Signaling-defective mutants of the B lymphocyte antigen receptor fail to associate with Ig-α and Ig-β/γ*
4. Monomeric and oligomeric complexes of the B cell antigen receptor
5. Polymer IgM assembly and secretion in lymphoid cells and nonlymphoid cell lines: Evidence that J chain is required for pentamer IgM synthesis
6. A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
7. Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
8. Receptor clustering as a cellular mechanism to control sensitivity
9. Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane
10. Tyrosine phosphorylation of components of the B cell antigen receptor following receptor crosslinking
11. Lipid rafts and signal transduction
12. A role for lipid rafts in B cell antigen receptor signaling and antigen targeting
13. 2+ flux
14. Transient translocation of the B cell receptor and Src homology 2 domain-containing inositol phosphatase to lipid rafts: Evidence toward a role in calcium regulation
15. Entry of B cell receptor into signaling domains is inhibited in tolerant B cells
16. Annexin V binds to viable B cells and colocalizes with a marker of lipid rafts upon B cell receptor activation
17. Differential sequestration of plasma membrane-associated B cell antigen receptor in mature and immature B cells into glycosphingolipid-enriched domains
18. Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain
19. B cell antigen receptor signaling occurs outside lipid rafts in immature B cells
20. Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex
21. Membrane compartmentation is required for efficient T cell activation
22. Antigen receptor-induced signal transduction imbalances associated with the negative selection of immature B cells
23. Widespread B29 (CD79b) gene defects and loss of expression in chronic lymphocytic lymphoma
24. Down-regulation of membrane immunoglobulin-associated proteins, MB-1, B29 and Lyn, in AIDS-lymphomas and related conditions
25. Discordant expression of immunoglobulin and its associated molecule mb-1/CD79a is frequently found in mediastinal large B cell lymphomas
26. Inhibition of intracellular transport of B cell antigen receptor complexes by Kaposi's sarcoma-associated herpesvirus K1
27. Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus
28. Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi's sarcoma-associated herpesvirus
29. Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus
30. Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EμLMP2A transgenic mice
31. Epstein-Barr virus co-opts lipid rafts to block the signaling and antigen transport functions of the BCR
32. Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases
33. Aberrant B cell receptor signaling from B29 (Igβ, CD79b) gene mutations of chronic B lymphocytic leukemia B cells
34. B-cell chronic lymphocytic leukemia: A bird of a different feather