Molecular modelling studies on the interactions of human DNA topoisomerase IB with pyridoxal-compounds

Biochimie

Volumn 89, Issue 4, 2007, Pages 468-473

  Christmann Franck, Serge ^b   Fermandjian, Serge ^b   Mirambeau, Gilles ^c   Der Garabedian, P Arsène ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b Ecole Normale Superieure de Cachan   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Human DNA topoisomerase IB; Molecular modelling; Pyridoxal 5 diphospho 5 adenosine; Pyridoxal 5 phosphate

Indexed keywords

ADENOSINE DIPHOSPHATE PYRIDOXAL; ALANINE RACEMASE; DNA TOPOISOMERASE; DNA TOPOISOMERASE 1B; DNA TOPOISOMERASE INHIBITOR; LYSINE; PYRIDOXAL; PYRIDOXAL 5 PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; ATOM; BACILLUS SUBTILIS; BINDING SITE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG BINDING; DRUG DNA INTERACTION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVE SITE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL;

BINDING SITES; DNA TOPOISOMERASES, TYPE I, EUKARYOTIC; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PYRIDOXAL;

BACILLUS SUBTILIS; PICHIA GUILLIERMONDII;

EID: 34247334283     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2006.10.007     Document Type: Article

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