Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death

Journal of Neurochemistry

Volumn 98, Issue 1, 2006, Pages 45-56

  Yamashita, Hiroshi ^a   Nakamura, Takeshi ^a   Takahashi, Tetsuya ^a   Nagano, Yoshito ^a   Hiji, Masanori ^a   Hirabayashi, Takahiro ^b   Amano, Taku ^a   Yagi, Takeshi ^b   Sakai, Norio ^a   Kohriyama, Tatsuo ^a   Matsumoto, Masayasu ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

synuclein; Dopaminergic neuron; Embryonic stem cell; Neuronal death; Oligodendrocyte; Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; CASPASE INHIBITOR; CELL NUCLEUS RECEPTOR; MUTANT PROTEIN; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; BRAIN MITOCHONDRION; CELL DIFFERENTIATION; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; DOPAMINERGIC NERVE CELL; EMBRYONIC STEM CELL; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; OLIGODENDROGLIA; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; SUBSTANTIA NIGRA; WILD TYPE;

ALPHA-SYNUCLEIN; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL DEATH; CELL DIFFERENTIATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MUTANT PROTEINS; N-METHYLASPARTATE; NERVE TISSUE PROTEINS; NEURONS; OXIDATIVE STRESS; PARKINSON DISEASE; PATCH-CLAMP TECHNIQUES; STEM CELLS; TRANSCRIPTION FACTORS;

EID: 33745063639     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03815.x     Document Type: Article

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