Emerging use of non-viral RNA interference in the brain

Biochemical Society Transactions

Volumn 35, Issue 2, 2007, Pages 411-415

  Cryan, J F ^a,b   Thakker, D R ^c   Hoyer, D ^d,e  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

^c MEDTRONIC INC   (United States)

^d NOVARTIS PHARMA AG   (Switzerland)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Gene knockdown; Neuropsychiatric disorder; Short interfering RNA (siRNA); Small hairpin RNA (shRNA); Target validation; Therapy

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; AGOUTI RELATED PROTEIN; ALPHA 2A ADRENERGIC RECEPTOR; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; CYCLOOXYGENASE 1; DOPAMINE TRANSPORTER; ENHANCED GREEN FLUORESCENT PROTEIN; GLUTAMATE RECEPTOR 2; PURINE P2X3 RECEPTOR; RNA INDUCED SILENCING COMPLEX; SEROTONIN TRANSPORTER; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; STAT PROTEIN; TYROSINE 3 MONOOXYGENASE;

BRAIN; BRAIN FUNCTION; CONFERENCE PAPER; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG RELEASE; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENE SILENCING; MENTAL DISEASE; NEUROLOGIC DISEASE; NEUROPATHIC PAIN; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OSMOTIC MINIPUMP; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RNA INTERFERENCE;

ANIMALS; BRAIN; BRAIN DISEASES; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM DISEASES; GENE EXPRESSION REGULATION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; MENTAL DISORDERS; MICE; MICE, TRANSGENIC; NEURONS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 34247109938     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0350411     Document Type: Conference Paper

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