Reducing hypothalmic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

BMC Neuroscience

Volumn 3, Issue , 2002, Pages

  Makimura, Hideo ^a   Mizuno, Tooru M ^a   Mastaitis, Jason W ^a   Agami, Reuven ^b   Mobbs, Charles V ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; MESSENGER RNA; AGOUTI-RELATED PROTEIN; GREEN FLUORESCENT PROTEIN; PHOTOPROTEIN; PROTEIN; SIGNAL PEPTIDE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; FOOD INTAKE; GENE FUNCTION; HYPOTHALAMUS; IMMUNOREACTIVITY; IN VIVO STUDY; METABOLIC RATE; MOUSE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; WEIGHT GAIN; WEIGHT REDUCTION; ANIMAL; ARCUATE NUCLEUS; BASAL METABOLIC RATE; BODY WEIGHT; C57BL MOUSE; CALORIMETRY; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; EATING; GENETICS; METABOLISM; OXYGEN CONSUMPTION; PHYSIOLOGY;

ANIMALS; ARCUATE NUCLEUS; BASAL METABOLISM; BODY WEIGHT; CALORIMETRY, INDIRECT; DOWN-REGULATION; EATING; GREEN FLUORESCENT PROTEINS; HYPOTHALAMUS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUMINESCENT PROTEINS; MICE; MICE, INBRED C57BL; OXYGEN CONSUMPTION; PROTEINS; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 0037038758     PISSN: 14712202     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2202-3-18     Document Type: Article

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