Dysequilibrium between caspases and their inhibitors in a mouse model for amyotrophic lateral sclerosis

Brain Research

Volumn 1148, Issue 1, 2007, Pages 234-242

  Tokuda, Eiichi ^a   Ono, Shin ichi ^a,b   Ishige, Kumiko ^a   Watanabe, Shunsuke ^a   Okawa, Eriko ^a   Ito, Yoshihisa ^a   Suzuki, Takashi ^a  

^a NIHON UNIVERSITY   (Japan)

^b Akiru Municipal General Hospital   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Apoptosis; Caspase; Fas; Mitochondria; Survivin

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; MESSENGER RNA; SUPEROXIDE DISMUTASE; SURVIVIN; X LINKED INHIBITOR OF APOPTOSIS;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CEREBELLUM; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MODEL; DISEASE SEVERITY; FAMILIAL DISEASE; FEMALE; MALE; MOUSE; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; SPINAL CORD; TRANSGENIC MOUSE; UPREGULATION; WILD TYPE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASES; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; MALE; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; NERVE DEGENERATION; OXIDATIVE STRESS; RNA, MESSENGER; SUPEROXIDE DISMUTASE; UP-REGULATION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

MUS; MUS MUSCULUS; RODENTIA;

EID: 34247102782     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.02.087     Document Type: Article

References (49)

1. Adida C., Crotty P.L., McGrath J., Berrebi D., Diebold J., and Altieri D.C. Developmentally regulated expression of the novel cancer antiapoptotic gene survivin in human and mouse differentiation. Am. J. Pathol. 152 (1998) 43-49
2. Ambrosini G., Adida C., and Altieri D.C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med. 3 (1997) 917-921
3. Blanc-Brude O.P., Yu J., Simosa H., Conte M.S., Sessa W.C., and Altieri D.C. Inhibitory of apoptosis protein survivin regulates vascular injury. Nat. Med. 8 (2002) 987-994
4. Bruijn L.I., Miller T.M., and Cleveland D.W. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu. Rev. Neurosci. 27 (2004) 723-749
5. Burstein E., Ganesh L., Dick R.D., Van De Sluis B., Wilkinson J.C., Klomp L.W.J., Wijmenga C., Brewer G.J., Nabel G.J., and Duckett C.S. A novel role for XIAP in copper homeostasis through regulation of MURR1. EMBO. J. 23 (2004) 244-254
6. Chiou S.K., Jones M.K., and Tarnawski A.S. Survivin. An anti-apoptosis protein. Its biological roles and implications for cancer and beyond. Med. Sci. Monit. 9 (2003) 143-147
7. Clement A.M., Nguyen M.D., Roberts E.A., Garcia M.L., Boillée S., Rule M., McMahon A.P., Doucette W., Siwek D., Ferrante R.J., Brown Jr. R.H., Julien J.P., Goldstein L.S.B., and Cleveland D.W. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science 302 (2003) 113-117
8. Cleveland D.W., and Rothstein J.D. From Charcot to Lou Gehring. Deciphering selective motor neuron death in ALS. Nat. Rev., Neurosci. 2 (2001) 806-819
9. Conway E.M., Pollefeyt S., Cornelissen J., Debaere I., Steiner-Mosonyi M., Ong K., Baens M., Collen D., and Schuh A.C. Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions. Blood 95 (2000) 1435-1442
10. Deguchi M., Shiraki K., Inoue H., Okano H., Ito T., Yamamoto T., Sugimoto K., Sakai T., Ohmori S., Murata K., Furusaka A., Hisatomi H., and Nakano T. Expression of survivin during liver regeneration. Biochem. Biophy. Res. Commun. 297 (2002) 59-64
11. Deveraux Q.L., Takahashi R., Salvesen G.S., and Reed J.C. X-linked IAP is direct inhibitor of cell-death proteases. Nature 388 (1997) 300-304
12. Elliott J.L. Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis. Mol. Brain Res. 95 (2001) 172-178
13. Friedlander R.M. Apoptosis and caspases in neurodegenerative diseases. N. Engl. J. Med. 348 (2003) 1365-1375
14. Fujita E., Jindo A., Matsuzaki H., Konishi H., Kikkawa U., and Momoi T. Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9. Biochem. Biophys. Res. Commun. 264 (1999) 550-555
15. Gong Y.H., Parsadanian A.S., Andreeva A., Snider W.D., and Elliott J.L. Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration. J. Neurosci. 20 (2000) 660-665
16. Guégan C., and Przedborsli S. Programmed cell death in amyotrophic lateral sclerosis. J. Clin. Invest. 111 (2003) 153-161
17. Guégan C., Vila M., Rosoklija G., Hays A.P., and Przedborsli S. Recruitment of the mitochondrial-dependent apoptosis pathway in amyotrophic lateral sclerosis. J. Neurosci. 21 (2001) 6569-6576
18. Guégan C., Vila M., Teissman P., Chen C., Onténiente B., Li M., Friedlander R.M., and Przedborski S. Instrumental activation of bid by caspase-1 in a transgenic mouse of ALS. Mol. Cell. Neurosci. 20 (2002) 553-562
19. Gurney M.E., Pu H., Chiu A.Y., Dal Canto M.C., Polchow C.Y., Alexander D.D., Caliendo J., Hentati A., Kwon Y.W., Deng H.X., Chen W., Zhai P., Sufit R.L., and Siddique T. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 264 (1994) 1772-1775
20. Inoue H., Tsukita K., Iwasato T., Suzuki Y., Tomioka M., Tateno M., Nagao M., Kawata A., Saido C.T., Miura M., Misawa H., Itohara S., and Takahashi R. The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model. EMBO J. 24 (2002) 6665-6674
21. Hengartner M.O. The biochemistry of apoptosis. Nature 407 (2000) 770-776
22. Hensley K., Floyd R.D., Gordon B., Mou S., Pye Q.N., Stewart C., West M., and Williamson K. Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. J. Neurochem. 82 (2002) 365-374
23. Ishigaki S., Liang Y., Yamamoto M., Niwa J., Ando Y., Yoshihara T., Takeuchi H., Doyu M., and Sobue G. X-liked inhibitor of apoptosis protein is involved in mutant SOD1-mediated neuronal degeneration. J. Neurochem. 82 (2002) 576-584
24. Kawamura K., Sato N., Fukuda J., Kodama H., Kumagai H., Tanikawa H., Shimizu Y., and Tanaka T. Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos. Dev. Biol. 256 (2003) 331-341
25. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
26. Levenson C.W. Trace metal regulation of normal apoptosis: from genes to behavior. Physiol. Behav. 86 (2005) 399-406
27. Li M., Ona V.O., Guégan C., Chen M., Jackson-Lewis V., Andrews L.J., Olszewski A.J., Stieg P.E., Lee J.P., Przedborski S., and Fliedlander R.M. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 288 (2000) 335-339
28. Lino M.M., Schneider C., and Caroni P. Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease. J. Neurosci. 22 (2002) 4825-4832
29. Matsushita K., Wu Y., Qiu J., Lang-Lazdunski L., Hirt L., Waeber C., Hyman B.T., Yuan J., and Moskowitz M.A. Fas receptor and neuronal cell death after spinal cord ischemia. J. Neurosci. 20 (2000) 6879-6887
30. Mufti A.R., Burstein E., Csomos R.A., Graf P.C.F., Wilkinson J.C., Dick R.D., Challa M., Son J.K., Bratton S.B., Su G.L., Brewer G.J., Jakob U., and Duckett C.S. XIAP is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders. Mol. Cell 21 (2006) 775-785
31. Nagata S. Apoptosis by death factor. Cell 88 (1997) 355-365
32. Ono S.I., Endo Y., Tokuda E., Ishige K., Tabata K., Asami S., Ito Y., and Suzuki T. Upregulation of metallothionein-I mRNA expression in a rodent model for amyotrophic lateral sclerosis. Biol. Trace Elem. Res. 113 (2006) 93-103
33. Pramatarova A., Laganiére J., Roussel J., Brisebois K., and Rouleau G.A. Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J. Neurosci. 21 (2001) 3369-3374
34. Pasinelli P., Houseweart M.K., Brown Jr. R.H., and Cleveland D.W. Caspase-1 and -3 are sequentially activated in motor neuron death in Cu, Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 13901-13906
35. Reaume A.G., Elliott J.L., Hoffman E.K., Kowall N.W., Ferrante R.J., Siwek D.F., Wilcok H.M., Flood D.G., Beal M.F., Brown Jr. R.H., Scott R.W., and Snider W.D. Motor neuron in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat. Genet. 13 (1996) 43-47
36. Ripps M.E., Huntley G.W., Hof P.R., Morrison J.H., and Gordon J.W. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 689-693
37. Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., Donaldoson D., Goto J., O'Regan J.P., Deng H.X., Rahmani Z., Krizus A., McKenna-Yasek D., Cayabyab A., Gaston S.M., Berger R., Tanzi R.E., Halperin J.J., Herzfeldt B., Van den Bergh R., Hung W.Y., Bird T., Deng G., Mulder D.W., Smyth C., Laing N.G., Soriano E., Pericak-Vance M.A., Haines J., Rouleau G.A., Gusella J.S., Horvitz H.R., and Brown Jr. R.H. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362 (1993) 59-62
38. Rowland L.P., and Shneider N.A. Amyotrophic lateral sclerosis. N. Engl. J. Med. 344 (2001) 1688-1700
39. Roy N., Deveraux Q.L., Takahashi R., Salvesen G.S., and Reed J.C. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO. J. 23 (1997) 6914-6925
40. Sathasivam S., and Shaw P.J. Apoptosis in amyotrophic lateral sclerosis. What is the evidence?. Lancet Neurol. 4 (2005) 500-509
41. Tokuda E., Ono S.I., Ishige K., Naganuma A., Ito Y., and Suzuki T. Metallothionein proteins expression, copper and zinc concentrations and lipid peroxidation level in a rodent model for amyotrophic lateral sclerosis. Toxicology 229 (2007) 33-41
42. Valentine J.S., and Hart P.J. Misfolded CuZnSOD and amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 3617-3622
43. Verhagen A.M., Coulson E.J., and Vaux D.L. Inhibitor of apoptosis proteins and their relatives. IAPs and other BIRPs. Genome Biol. 2 (2001) 3009.1-3009.10
44. Vukosavic S., Stefanis L., Jackson-Lewis V., Guégan C., Romero N., Chen C., Dubois-Dauphin M., and Przedborski S. Delaying caspase activation by Bcl-2. A clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis. J. Neurosci. 20 (2000) 9119-9125
45. Wiedau-Pazos M., Goto J.J., Rabizadeh S., Gralla E.B., Roe J.A., Lee M.K., Valentine J.S., and Bredesen D.E. Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science 271 (1996) 515-518
46. Wong P.C., Pardo C.A., Borchelt D.R., Lee M.K., Copeland N.G., Jenkins N.A., Sisodia S.S., Cleveland D.W., and Price D.L. An adverse property of familial ALD-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14 (1995) 1105-1116
47. Wootz H., Hansson I., Korhonen L., and Lindholm D. Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS. Biochem. Biophys. Res. Commun. 322 (2004) 281-286
48. Wootz H., Hansson I., Korhonen L., and Lindholm D. XIAP decrease caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice. Exp. Cell Res. 312 (2006) 1890-1898
49. Yoshihara T., Ishigaki S., Yamamoto M., Liang Y., Niwa J., Takeuchi H., Doyu M., and Sobue G. Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis. J. Neurochem. 80 (2002) 158-167