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Volumn 30, Issue 2, 2007, Pages 499-507

An imbalance between Smad and MAPK pathways is responsible for TGF-β tumor promoting effects in high-grade gliomas

Author keywords

High grade glioma; MAPK pathway; Smad pathway; TGF

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; OLIGONUCLEOTIDE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2;

EID: 34047270254     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (36)

References (72)
  • 1
    • 0019465899 scopus 로고
    • Transforming growth factor production by chemically transformed cells
    • Moses HL, Branum EL, Proper JA and Robinson RA: Transforming growth factor production by chemically transformed cells. Cancer Res 41: 2841-2848, 1981.
    • (1981) Cancer Res , vol.41 , pp. 2841-2848
    • Moses, H.L.1    Branum, E.L.2    Proper, J.A.3    Robinson, R.A.4
  • 2
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumor progression
    • Thiery JP: Epithelial-mesenchymal transitions in tumor progression. Nat Rev Cancer 2: 442-454, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 3
    • 0035873075 scopus 로고    scopus 로고
    • Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by bcl-2 and Transforming Growth Factor-β2
    • Wick W, Grimmel C, Wild-Bode C, Platten M, Arpin M and Weller M: Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by bcl-2 and Transforming Growth Factor-β2. J Neurosci 21: 3360-3368, 2001.
    • (2001) J Neurosci , vol.21 , pp. 3360-3368
    • Wick, W.1    Grimmel, C.2    Wild-Bode, C.3    Platten, M.4    Arpin, M.5    Weller, M.6
  • 5
    • 0034673243 scopus 로고    scopus 로고
    • TGF-β1 and TGF-β2 promote glioma cell migration cia up-regulation of alphaVbeta3 integrin expression
    • Platten M, Wick W, Wild-Bode C, Aulwurm S, Dichgans J and Weller M: TGF-β1 and TGF-β2 promote glioma cell migration cia up-regulation of alphaVbeta3 integrin expression. Biochem Biophys Res Commun 269: 607-611, 2000.
    • (2000) Biochem Biophys Res Commun , vol.269 , pp. 607-611
    • Platten, M.1    Wick, W.2    Wild-Bode, C.3    Aulwurm, S.4    Dichgans, J.5    Weller, M.6
  • 6
    • 0033934907 scopus 로고    scopus 로고
    • Expression of TGF-beta isoforms, TGF-beta receptors, and SMAD molecules at different stages of human glioma
    • Kjellman C, Olofsson SP, Hansson O, et al: Expression of TGF-beta isoforms, TGF-beta receptors, and SMAD molecules at different stages of human glioma. Int J Cancer 89: 251-258, 2000.
    • (2000) Int J Cancer , vol.89 , pp. 251-258
    • Kjellman, C.1    Olofsson, S.P.2    Hansson, O.3
  • 7
    • 0030021142 scopus 로고    scopus 로고
    • Transforming growth factor-beta mediated autocrine growth regulation of gliomas as detected with phosphorothioate antisense oligonucleotides
    • Jachimczak P, Hessdorfer B, Fabel-Schulte K, Wismeth C, Brysch W and Schlingensiepen KH: Transforming growth factor-beta mediated autocrine growth regulation of gliomas as detected with phosphorothioate antisense oligonucleotides. Int J Cancer 65: 332-337, 1996.
    • (1996) Int J Cancer , vol.65 , pp. 332-337
    • Jachimczak, P.1    Hessdorfer, B.2    Fabel-Schulte, K.3    Wismeth, C.4    Brysch, W.5    Schlingensiepen, K.H.6
  • 8
    • 0027131252 scopus 로고
    • Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival
    • Friess H, Yamanaka Y, Buchler M, Ebert M, Beger HG and Gold LI: Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology 105: 1846-1856, 1993.
    • (1993) Gastroenterology , vol.105 , pp. 1846-1856
    • Friess, H.1    Yamanaka, Y.2    Buchler, M.3    Ebert, M.4    Beger, H.G.5    Gold, L.I.6
  • 13
    • 0035865158 scopus 로고    scopus 로고
    • Malignant glioma biology: Role for TGF-β in growth, motility, angiogenesis and immune escape
    • Platten M, Wick W and Weller M: Malignant glioma biology: role for TGF-β in growth, motility, angiogenesis and immune escape. Microsc Res Tech 52: 401-410, 2001.
    • (2001) Microsc Res Tech , vol.52 , pp. 401-410
    • Platten, M.1    Wick, W.2    Weller, M.3
  • 14
    • 0031685620 scopus 로고    scopus 로고
    • TGF-β signal transduction
    • Massagué J: TGF-β signal transduction. Annu Rev Biochem 67: 753-791, 1998.
    • (1998) Annu Rev Biochem , vol.67 , pp. 753-791
    • Massagué, J.1
  • 15
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signaling
    • Derynck R and Zhang YE: Smad-dependent and Smad-independent pathways in TGF-beta family signaling. Nature 425: 577-584, 2003.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 16
    • 0035689762 scopus 로고    scopus 로고
    • Malignant cells, directors of the malignant process: Role of transforming growth factor-beta
    • Teicher BA: Malignant cells, directors of the malignant process: role of transforming growth factor-beta. Cancer Metastasis Rev 20: 133-143, 2001.
    • (2001) Cancer Metastasis Rev , vol.20 , pp. 133-143
    • Teicher, B.A.1
  • 17
    • 0034796457 scopus 로고    scopus 로고
    • The TGF-β receptor activation process: An inhibitor- to substratebinding switch
    • Huse M, Muir TW, Xu L, Chen YG, Kuriyan J and Massagué J: The TGF-β receptor activation process: an inhibitor- to substratebinding switch. Mol Cell 8: 671-682, 2001.
    • (2001) Mol Cell , vol.8 , pp. 671-682
    • Huse, M.1    Muir, T.W.2    Xu, L.3    Chen, Y.G.4    Kuriyan, J.5    Massagué, J.6
  • 18
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S and Gauthier JM: Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J 17: 3091-3100, 1998.
    • (1998) EMBO J , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Ten Dijke, P.4    Huet, S.5    Gauthier, J.M.6
  • 21
    • 0031930657 scopus 로고    scopus 로고
    • The role of transforming growth factor beta in glioma progression
    • Jennings MT and Pietenpol JA: The role of transforming growth factor beta in glioma progression. J Neurooncol 36: 123-140, 1998.
    • (1998) J Neurooncol , vol.36 , pp. 123-140
    • Jennings, M.T.1    Pietenpol, J.A.2
  • 24
    • 0032102209 scopus 로고    scopus 로고
    • Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway
    • Schwachtgen JL, Houston P, Campbell C, Sukhatme V and Braddock M: Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway. J Clin Invest 101: 2540-2549, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 2540-2549
    • Schwachtgen, J.L.1    Houston, P.2    Campbell, C.3    Sukhatme, V.4    Braddock, M.5
  • 25
    • 0021234673 scopus 로고    scopus 로고
    • Elevated expression of the human ras oncogene family in premalignant and malignant tumours of the colorectum
    • Spandidos DA and Kerr IB: Elevated expression of the human ras oncogene family in premalignant and malignant tumours of the colorectum. Br J Cancer 49: 681-688, 1998.
    • (1998) Br J Cancer , vol.49 , pp. 681-688
    • Spandidos, D.A.1    Kerr, I.B.2
  • 28
    • 0035501062 scopus 로고    scopus 로고
    • TGF-beta signaling in cancer - A double-edged sword
    • Akhurst RJ and Derynck R: TGF-beta signaling in cancer - a double-edged sword. Trends Cell Biol 11: S44-S51, 2001.
    • (2001) Trends Cell Biol , vol.11
    • Akhurst, R.J.1    Derynck, R.2
  • 29
    • 0033106484 scopus 로고    scopus 로고
    • A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras
    • Kretzschmar M, Doody J, Timokhina I and Massague J: A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras. Genes Dev 13: 804-816, 1999.
    • (1999) Genes Dev , vol.13 , pp. 804-816
    • Kretzschmar, M.1    Doody, J.2    Timokhina, I.3    Massague, J.4
  • 30
    • 0034666839 scopus 로고    scopus 로고
    • Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: A mechanism leading to increased malignancy in epithelial cells
    • Lehmann K, Janda E, Pierreux CE, Rytomaa M, Schulze A, McMahon M, Hill CS, Beug H and Downward J: Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells. Genes Dev 14: 2610-2622, 2000.
    • (2000) Genes Dev , vol.14 , pp. 2610-2622
    • Lehmann, K.1    Janda, E.2    Pierreux, C.E.3    Rytomaa, M.4    Schulze, A.5    McMahon, M.6    Hill, C.S.7    Beug, H.8    Downward, J.9
  • 31
    • 0035004208 scopus 로고    scopus 로고
    • Specific inhibition of transforming growth factor-beta2 expression in human osteoblast cells by antisense phosphorothioate oligonucleotides
    • Shen ZJ, Kim SK, Kwon OS, Lee YS and Moon BJ: Specific inhibition of transforming growth factor-beta2 expression in human osteoblast cells by antisense phosphorothioate oligonucleotides. Eur J Biochem 268: 2331-2337, 2001.
    • (2001) Eur J Biochem , vol.268 , pp. 2331-2337
    • Shen, Z.J.1    Kim, S.K.2    Kwon, O.S.3    Lee, Y.S.4    Moon, B.J.5
  • 32
    • 0024444320 scopus 로고
    • Autocrine tumor cell growth-inhibiting activities from human malignant melanoma
    • Bogdahn U, Apfel R, Hahn M, Gerlach M, Behl C, Hoppe J and Martin R: Autocrine tumor cell growth-inhibiting activities from human malignant melanoma. Cancer Res 49: 5358-5363, 1989.
    • (1989) Cancer Res , vol.49 , pp. 5358-5363
    • Bogdahn, U.1    Apfel, R.2    Hahn, M.3    Gerlach, M.4    Behl, C.5    Hoppe, J.6    Martin, R.7
  • 33
    • 0035379644 scopus 로고    scopus 로고
    • Dual growth arrest pathways in astrocytes and astrocytic tumors in response to Raf-1 activation
    • Fanton CP, McMahon M and Pieper RO: Dual growth arrest pathways in astrocytes and astrocytic tumors in response to Raf-1 activation. J Biol Chem 276: 18871-18877, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 18871-18877
    • Fanton, C.P.1    McMahon, M.2    Pieper, R.O.3
  • 35
    • 0026541255 scopus 로고
    • Differential expression of transforming growth factor-β, -β2, snd -β3 by glioblastoma cells, astrocytes and microglia
    • Constam DB, Philipp J, Malipiero UV, ten Dijke P, Schachner M and Fontana A: Differential expression of transforming growth factor-β, -β2, snd -β3 by glioblastoma cells, astrocytes and microglia. J Immunol 148: 1404, 1992.
    • (1992) J Immunol , vol.148 , pp. 1404
    • Constam, D.B.1    Philipp, J.2    Malipiero, U.V.3    Ten Dijke, P.4    Schachner, M.5    Fontana, A.6
  • 36
    • 0033521118 scopus 로고    scopus 로고
    • INK4B induction and growth inhibition in astrocytes is Smad3-dependent and a pathway prominently altered in human glioma cell lines
    • INK4B induction and growth inhibition in astrocytes is Smad3-dependent and a pathway prominently altered in human glioma cell lines. J Biol Chem 274: 35053-35058, 1998.
    • (1998) J Biol Chem , vol.274 , pp. 35053-35058
    • Rich, J.B.1    Ming, Z.2    Datto, M.B.3    Bigner, D.B.4    Xiao-Fan, W.5
  • 38
    • 0030004872 scopus 로고    scopus 로고
    • Facilitating oligonucleotides delivery: Helping antisense to deliver on its promise
    • Gertwitz AM, Stein CA and Glazer PM: Facilitating oligonucleotides delivery: helping antisense to deliver on its promise. Proc Natl Acad Sci USA 93: 3161-3163, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3161-3163
    • Gertwitz, A.M.1    Stein, C.A.2    Glazer, P.M.3
  • 39
    • 78650276697 scopus 로고    scopus 로고
    • Antisense strategy: Biological utility and prospects in the treatment of hematological malignancies
    • Warzocha K and Wotowiec D: Antisense strategy: biological utility and prospects in the treatment of hematological malignancies. Leuk Lymphoma 82: 83-90, 1997.
    • (1997) Leuk Lymphoma , vol.82 , pp. 83-90
    • Warzocha, K.1    Wotowiec, D.2
  • 40
    • 0029164957 scopus 로고
    • Cell-surface perturbations of the epidermal growth factor and vascular endothelial growth factor receptors by phosphorothioate oligodeoxynucleotides
    • Fennewald SM and Rando RF: Cell-surface perturbations of the epidermal growth factor and vascular endothelial growth factor receptors by phosphorothioate oligodeoxynucleotides. J Biol Chem 270: 21718-21721, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 21718-21721
    • Fennewald, S.M.1    Rando, R.F.2
  • 41
    • 0028815149 scopus 로고
    • Inhibition of high affinity basic fibroblast growth factor binding by oligonucleotides
    • Guvakova MA, Yakubov LA, Vlodavsky I, Tonkison JL and Stein CA: Inhibition of high affinity basic fibroblast growth factor binding by oligonucleotides. J Biol Chem 270: 2620-2627, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 2620-2627
    • Guvakova, M.A.1    Yakubov, L.A.2    Vlodavsky, I.3    Tonkison, J.L.4    Stein, C.A.5
  • 42
    • 0030987371 scopus 로고    scopus 로고
    • Cell-surface perturbations of the epidermal growth factor and vascular endothelial growth factor receptors by phosphorothioate oligodeoxynucleotides
    • Rockwell P, O'Connor WJ, King K, Goldstein NI, Zhang LM and Stein CA: Cell-surface perturbations of the epidermal growth factor and vascular endothelial growth factor receptors by phosphorothioate oligodeoxynucleotides. Proc Natl Acad Sci USA 94: 6523-6528, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6523-6528
    • Rockwell, P.1    O'Connor, W.J.2    King, K.3    Goldstein, N.I.4    Zhang, L.M.5    Stein, C.A.6
  • 44
    • 0035800838 scopus 로고    scopus 로고
    • Oncogenic Ras represses Transforming Growth Factor-β/Smad signaling by degrading tumor suppressor Smad 4
    • Saha D, Datta PK and Beauchamp RD: Oncogenic Ras represses Transforming Growth Factor-β/Smad signaling by degrading tumor suppressor Smad 4. J Biol Chem 276: 29531-29537, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 29531-29537
    • Saha, D.1    Datta, P.K.2    Beauchamp, R.D.3
  • 45
    • 0033257926 scopus 로고    scopus 로고
    • Ubiquitin-dependent degradation of TGF-β-activated Smad2
    • Lo RS and Massagué J: Ubiquitin-dependent degradation of TGF-β-activated Smad2. Nat Cell Biol 1: 472-478, 1999.
    • (1999) Nat Cell Biol , vol.1 , pp. 472-478
    • Lo, R.S.1    Massagué, J.2
  • 46
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-β signaling from cell membrane to the nucleus
    • Shi Y and Massagué J: Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 113: 685-700, 2003.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massagué, J.2
  • 47
    • 0029092309 scopus 로고
    • The Ras suppressor RSU-1 localizes to 10p13 and its expression in the U251 glioblastoma cell line correlates with a decrease in growth rate and tumorigenic potential
    • Tsuda T, Marinetti MR, Masuelli L and Cutler ML: The Ras suppressor RSU-1 localizes to 10p13 and its expression in the U251 glioblastoma cell line correlates with a decrease in growth rate and tumorigenic potential. Oncogene 11: 397-403, 1995.
    • (1995) Oncogene , vol.11 , pp. 397-403
    • Tsuda, T.1    Marinetti, M.R.2    Masuelli, L.3    Cutler, M.L.4
  • 49
    • 11244344906 scopus 로고    scopus 로고
    • Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes
    • Dasgupta B, Li W, Perry A and Gutmann DH: Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes. Cancer Res 65: 236-245, 2005.
    • (2005) Cancer Res , vol.65 , pp. 236-245
    • Dasgupta, B.1    Li, W.2    Perry, A.3    Gutmann, D.H.4
  • 50
    • 0034644472 scopus 로고    scopus 로고
    • TGF-β signaling in growth control, cancer and heritable disorders
    • Massagué J, Blain SW and Lo RS: TGF-β signaling in growth control, cancer and heritable disorders. Cell 103: 395-409, 2000.
    • (2000) Cell , vol.103 , pp. 395-409
    • Massagué, J.1    Blain, S.W.2    Lo, R.S.3
  • 51
    • 0033585086 scopus 로고    scopus 로고
    • Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells
    • Calonge MJ and Massague J: Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells. J Biol Chem 274: 33637-33643, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 33637-33643
    • Calonge, M.J.1    Massague, J.2
  • 52
    • 0029662049 scopus 로고    scopus 로고
    • TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
    • Oft M, Peli J, Rudaz C, Schwarz H, Beug H and Reichmann E: TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev 10: 2462-2477, 1996.
    • (1996) Genes Dev , vol.10 , pp. 2462-2477
    • Oft, M.1    Peli, J.2    Rudaz, C.3    Schwarz, H.4    Beug, H.5    Reichmann, E.6
  • 53
    • 33646248388 scopus 로고    scopus 로고
    • The Raf-1 pathway: A molecular target for treatment of select neuroendocrine tumors?
    • Kunnimalaiyaan M and Chen H: The Raf-1 pathway: a molecular target for treatment of select neuroendocrine tumors? Anticancer Drugs 17: 139-142, 2006.
    • (2006) Anticancer Drugs , vol.17 , pp. 139-142
    • Kunnimalaiyaan, M.1    Chen, H.2
  • 54
    • 0032571388 scopus 로고    scopus 로고
    • Kinase suppressor of Ras inhibits the activation of extracellular ligand-regulated (ERK) mitogen-activated protein (MAP) kinase by growth factors, activated Ras, and Ras effectors
    • Joneson T, Fulton JA, Volle DJ, Chaika OV, Bar-Sagi D and Lewis RE: Kinase suppressor of Ras inhibits the activation of extracellular ligand-regulated (ERK) mitogen-activated protein (MAP) kinase by growth factors, activated Ras, and Ras effectors. J Biol Chem 273: 7743-7748, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 7743-7748
    • Joneson, T.1    Fulton, J.A.2    Volle, D.J.3    Chaika, O.V.4    Bar-Sagi, D.5    Lewis, R.E.6
  • 55
    • 0034667593 scopus 로고    scopus 로고
    • Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
    • Kolch W: Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J 351: 289-305, 2000.
    • (2000) Biochem J , vol.351 , pp. 289-305
    • Kolch, W.1
  • 56
    • 0035504758 scopus 로고    scopus 로고
    • Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells
    • Besson A, Davy A, Robbins SM and Yong VW: Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells. Oncogene 20: 7398-7407, 2001.
    • (2001) Oncogene , vol.20 , pp. 7398-7407
    • Besson, A.1    Davy, A.2    Robbins, S.M.3    Yong, V.W.4
  • 57
    • 0034806841 scopus 로고    scopus 로고
    • Agonists of the P2Y(AC)-receptor activate MAP kinase by a ras-independent pathway in rat C6 glioma
    • Grobben B, Claes P, van Kolen K, Roymans D, Fransen P, Sys SU and Slegers H: Agonists of the P2Y(AC)-receptor activate MAP kinase by a ras-independent pathway in rat C6 glioma. J Neurochem 78: 1325-1338, 2001.
    • (2001) J Neurochem , vol.78 , pp. 1325-1338
    • Grobben, B.1    Claes, P.2    Van Kolen, K.3    Roymans, D.4    Fransen, P.5    Sys, S.U.6    Slegers, H.7
  • 58
    • 33747247603 scopus 로고    scopus 로고
    • The mitogen-activated/extracellular signal-regulated kinase kinase 1/2 inhibitor U0126 induces glial fibrillary acidic protein expression and reduces the proliferation and migration of C6 glioma cells
    • Lind CR, Gray CW, Pearson AG, Cameron RE, O'Carroll SJ, Narayan PJ, Lim J and Dragunow M: The mitogen-activated/extracellular signal-regulated kinase kinase 1/2 inhibitor U0126 induces glial fibrillary acidic protein expression and reduces the proliferation and migration of C6 glioma cells. Neuroscience 141: 1925-1933, 2006.
    • (2006) Neuroscience , vol.141 , pp. 1925-1933
    • Lind, C.R.1    Gray, C.W.2    Pearson, A.G.3    Cameron, R.E.4    O'Carroll, S.J.5    Narayan, P.J.6    Lim, J.7    Dragunow, M.8
  • 61
    • 0036291475 scopus 로고    scopus 로고
    • PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases
    • Kotaja N, Karvonen U, Janne OA and Palvimo JJ: PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. Mol Cell Biol 22: 5222-5234, 2002.
    • (2002) Mol Cell Biol , vol.22 , pp. 5222-5234
    • Kotaja, N.1    Karvonen, U.2    Janne, O.A.3    Palvimo, J.J.4
  • 65
    • 0034210286 scopus 로고    scopus 로고
    • Chromosomal mapping and genomic organization of an evolutionarily conserved zinc finger gene ZNF277
    • Liang H, Guo W and Nagarajan L: Chromosomal mapping and genomic organization of an evolutionarily conserved zinc finger gene ZNF277. Genomics 66: 226-228, 2000.
    • (2000) Genomics , vol.66 , pp. 226-228
    • Liang, H.1    Guo, W.2    Nagarajan, L.3
  • 66
    • 0346373729 scopus 로고    scopus 로고
    • Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins
    • Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K and Fruh K: Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. J Virol 78: 1109-1120, 2004.
    • (2004) J Virol , vol.78 , pp. 1109-1120
    • Bartee, E.1    Mansouri, M.2    Hovey Nerenberg, B.T.3    Gouveia, K.4    Fruh, K.5
  • 67
    • 9144252038 scopus 로고    scopus 로고
    • Complete sequencing and characterization of 21,243 full-length human cDNAs
    • Ota T, Suzuki Y, Nishikawa T, Otsuki T, et al: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet 36: 40-45, 2004.
    • (2004) Nat Genet , vol.36 , pp. 40-45
    • Ota, T.1    Suzuki, Y.2    Nishikawa, T.3    Otsuki, T.4
  • 69
    • 8544237014 scopus 로고    scopus 로고
    • Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia
    • Kwak KS, Zhou X, Solomon V, Baracos VE, Davis J, Bannon AW, Boyle WJ, Lacey DL and Han HQ: Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia. Cancer Res 64: 8193-8198, 2005.
    • (2005) Cancer Res , vol.64 , pp. 8193-8198
    • Kwak, K.S.1    Zhou, X.2    Solomon, V.3    Baracos, V.E.4    Davis, J.5    Bannon, A.W.6    Boyle, W.J.7    Lacey, D.L.8    Han, H.Q.9
  • 70
    • 0030605426 scopus 로고    scopus 로고
    • Identification of a novel human gene containing the tetratricopeptide repeat domain from the Down syndrome region of chromosome 21
    • Ohira M, Ootsuyama A, Suzuki E, Ichikawa H, Seki N, Nagase T, Nomura N and Ohki M: Identification of a novel human gene containing the tetratricopeptide repeat domain from the Down syndrome region of chromosome 21. DNA Res 3: 9-16, 1996.
    • (1996) DNA Res , vol.3 , pp. 9-16
    • Ohira, M.1    Ootsuyama, A.2    Suzuki, E.3    Ichikawa, H.4    Seki, N.5    Nagase, T.6    Nomura, N.7    Ohki, M.8
  • 71
    • 0034192404 scopus 로고    scopus 로고
    • A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres
    • Hastie CJ, Carnegie GK, Morrice N and Cohen PT: A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres. Biochem J 3: 845-855, 2000.
    • (2000) Biochem J , vol.3 , pp. 845-855
    • Hastie, C.J.1    Carnegie, G.K.2    Morrice, N.3    Cohen, P.T.4
  • 72
    • 0033563149 scopus 로고    scopus 로고
    • Cloning and characterization of RNF6, a novel RING finger gene mapping to 13q12
    • MacDonald DH, Lahiri D, Sampath A, Chase A, Sohal J and Cross NC: Cloning and characterization of RNF6, a novel RING finger gene mapping to 13q12. Genomics 58: 94-97, 1999.
    • (1999) Genomics , vol.58 , pp. 94-97
    • MacDonald, D.H.1    Lahiri, D.2    Sampath, A.3    Chase, A.4    Sohal, J.5    Cross, N.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.