-
1
-
-
0027486269
-
Distribution of the anticonvulsant felbamate to cerebrospinal fluid and brain tissue of adult and neonatal rats
-
Adusumalli V.E., Wichmann J.K., Kucharczyk N., and Sofia R.D. Distribution of the anticonvulsant felbamate to cerebrospinal fluid and brain tissue of adult and neonatal rats. Drug Metab. Dispos. 21 (1993) 1079-1085
-
(1993)
Drug Metab. Dispos.
, vol.21
, pp. 1079-1085
-
-
Adusumalli, V.E.1
Wichmann, J.K.2
Kucharczyk, N.3
Sofia, R.D.4
-
2
-
-
0027980182
-
Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate
-
Adusumalli V.E., Wichmann J.K., Kucharczyk N., Kamin M., Sofia R.D., French J., Sperling M., Bourgeois B., Devinsky O., Dreifuss F.E., Kuzniecky R.I., Faught E., et al. Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate. Drug Metab. Dispos. 22 (1994) 168-170
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 168-170
-
-
Adusumalli, V.E.1
Wichmann, J.K.2
Kucharczyk, N.3
Kamin, M.4
Sofia, R.D.5
French, J.6
Sperling, M.7
Bourgeois, B.8
Devinsky, O.9
Dreifuss, F.E.10
Kuzniecky, R.I.11
Faught, E.12
-
3
-
-
0034967810
-
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels
-
Bertrand S., Ng G.Y., Purisai M.G., Wolfe S.E., Severidt M.W., Nouel D., Robitaille R., Low M.J., O'Neill G.P., Metters K., Lacaille J.C., Chronwall B.M., et al. The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels. J. Pharmacol. Exp. Ther. 298 (2001) 15-24
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 15-24
-
-
Bertrand, S.1
Ng, G.Y.2
Purisai, M.G.3
Wolfe, S.E.4
Severidt, M.W.5
Nouel, D.6
Robitaille, R.7
Low, M.J.8
O'Neill, G.P.9
Metters, K.10
Lacaille, J.C.11
Chronwall, B.M.12
-
4
-
-
0030682180
-
Levetiracetam (ucb L059) affects in vitro models of epilepsy in CA3 pyramidal neurons without altering normal synaptic transmission
-
Birnstiel S., Wulfert E., and Beck S.G. Levetiracetam (ucb L059) affects in vitro models of epilepsy in CA3 pyramidal neurons without altering normal synaptic transmission. Naunyn Schmiedebergs Arch. Pharmacol. 356 (1997) 611-618
-
(1997)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.356
, pp. 611-618
-
-
Birnstiel, S.1
Wulfert, E.2
Beck, S.G.3
-
5
-
-
0025068791
-
(R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier
-
Braestrup C., Nielsen E.B., Sonnewald U., Knutsen L.J., Andersen K.E., Jansen J.A., Frederiksen K., Andersen P.H., Mortensen A., and Suzdak P.D. (R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier. J. Neurochem. 54 (1990) 639-647
-
(1990)
J. Neurochem.
, vol.54
, pp. 639-647
-
-
Braestrup, C.1
Nielsen, E.B.2
Sonnewald, U.3
Knutsen, L.J.4
Andersen, K.E.5
Jansen, J.A.6
Frederiksen, K.7
Andersen, P.H.8
Mortensen, A.9
Suzdak, P.D.10
-
6
-
-
0029122730
-
Action of GP 47779, the active metabolite of oxcarbazepine, on the corticostriatal system. I. Modulation of corticostriatal synaptic transmission
-
Calabresi P., De Murtas M., Stefani A., Pisani A., Sancesario G., Mercuri N.B., and Bernardi G. Action of GP 47779, the active metabolite of oxcarbazepine, on the corticostriatal system. I. Modulation of corticostriatal synaptic transmission. Epilepsia 36 (1995) 990-996
-
(1995)
Epilepsia
, vol.36
, pp. 990-996
-
-
Calabresi, P.1
De Murtas, M.2
Stefani, A.3
Pisani, A.4
Sancesario, G.5
Mercuri, N.B.6
Bernardi, G.7
-
7
-
-
34047211993
-
Effects of valproate on action potentials and repetitive firing of CA1 pyramidal cells in the hippocampal slice preparation
-
Abstract 17.19
-
Capek R., and Esplin B. Effects of valproate on action potentials and repetitive firing of CA1 pyramidal cells in the hippocampal slice preparation. Soc. Neurosci. Abstr. 12 (1986) 46 Abstract 17.19
-
(1986)
Soc. Neurosci. Abstr.
, vol.12
, pp. 46
-
-
Capek, R.1
Esplin, B.2
-
8
-
-
0026443902
-
An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels
-
Cheung H., Kamp D., and Harris E. An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels. Epilepsy Res. 13 (1992) 107-112
-
(1992)
Epilepsy Res.
, vol.13
, pp. 107-112
-
-
Cheung, H.1
Kamp, D.2
Harris, E.3
-
9
-
-
0028086877
-
Selective antagonism of the anticonvulsant effects of felbamate by glycine
-
Coffin V., Cohen-Williams M., and Barnett A. Selective antagonism of the anticonvulsant effects of felbamate by glycine. Eur. J. Pharmacol. 256 (1994) R9-R10
-
(1994)
Eur. J. Pharmacol.
, vol.256
-
-
Coffin, V.1
Cohen-Williams, M.2
Barnett, A.3
-
10
-
-
0031414052
-
Antiepileptic drug cellular mechanisms of action: Where does lamotrigine fit in?
-
Coulter D.A. Antiepileptic drug cellular mechanisms of action: Where does lamotrigine fit in?. J. Child Neurol. 12 Suppl. 1 (1997) S2-S9
-
(1997)
J. Child Neurol.
, vol.12
, Issue.SUPPL. 1
-
-
Coulter, D.A.1
-
11
-
-
0024324889
-
Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons
-
Coulter D.A., Huguenard J.R., and Prince D.A. Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons. Ann. Neurol. 25 (1989) 582-593
-
(1989)
Ann. Neurol.
, vol.25
, pp. 582-593
-
-
Coulter, D.A.1
Huguenard, J.R.2
Prince, D.A.3
-
12
-
-
0000337336
-
Selective effects of topiramate on sustained repetitive firing and spontaneous bursting in cultured hippocampal neurons
-
Coulter D.A., Sombati S., and DeLorenzo R.J. Selective effects of topiramate on sustained repetitive firing and spontaneous bursting in cultured hippocampal neurons. Epilepsia 34 Suppl. 2 (1983) 123
-
(1983)
Epilepsia
, vol.34
, Issue.SUPPL. 2
, pp. 123
-
-
Coulter, D.A.1
Sombati, S.2
DeLorenzo, R.J.3
-
13
-
-
0002273388
-
Other antiepileptic drugs. Oxcarbazepine
-
Levy R.H., Mattson R.H., and Meldrum B.S. (Eds), Raven Press Ltd., New York
-
Dam M., and Ostergaard L.H. Other antiepileptic drugs. Oxcarbazepine. In: Levy R.H., Mattson R.H., and Meldrum B.S. (Eds). "Antiepileptic Drugs". 4th ed. (1995), Raven Press Ltd., New York 987-995
-
(1995)
"Antiepileptic Drugs". 4th ed.
, pp. 987-995
-
-
Dam, M.1
Ostergaard, L.H.2
-
14
-
-
0024494368
-
A double-blind study comparing oxcarbazepine and carbamazepine in patients with newly diagnosed, previously untreated epilepsy
-
Dam M., Ekberg R., Loyning Y., Waltimo O., and Jakobsen K. A double-blind study comparing oxcarbazepine and carbamazepine in patients with newly diagnosed, previously untreated epilepsy. Epilepsy Res. 3 (1989) 70-76
-
(1989)
Epilepsy Res.
, vol.3
, pp. 70-76
-
-
Dam, M.1
Ekberg, R.2
Loyning, Y.3
Waltimo, O.4
Jakobsen, K.5
-
15
-
-
30744454021
-
Phenytoin and other hydantoins: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
DeLorenzo R.J., and Sun D.A. Phenytoin and other hydantoins: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 551-564
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 551-564
-
-
DeLorenzo, R.J.1
Sun, D.A.2
-
16
-
-
0034128349
-
Effects of topiramate on sustained repetitive firing and spontaneous recurrent seizure discharges in cultured hippocampal neurons
-
DeLorenzo R.J., Sombati S., and Coulter D.A. Effects of topiramate on sustained repetitive firing and spontaneous recurrent seizure discharges in cultured hippocampal neurons. Epilepsia 41 Suppl. 1 (2000) S40-S44
-
(2000)
Epilepsia
, vol.41
, Issue.SUPPL. 1
-
-
DeLorenzo, R.J.1
Sombati, S.2
Coulter, D.A.3
-
17
-
-
0028021395
-
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice
-
De Sarro G., Ongini E., Bertorelli R., Aguglia U., and De Sarro A. Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice. Eur. J. Pharmacol. 262 (1994) 11-19
-
(1994)
Eur. J. Pharmacol.
, vol.262
, pp. 11-19
-
-
De Sarro, G.1
Ongini, E.2
Bertorelli, R.3
Aguglia, U.4
De Sarro, A.5
-
18
-
-
27944463102
-
Rapid kindling in preclinical anti-epileptic drug development: The effect of levetiracetam
-
De Smedt T., Vonck K., Raedt R., Dedeurwaerdere S., Claeys P., Legros B., Wyckhuys T., Wadman W., and Boon P. Rapid kindling in preclinical anti-epileptic drug development: The effect of levetiracetam. Epilepsy Res. 67 (2005) 109-116
-
(2005)
Epilepsy Res.
, vol.67
, pp. 109-116
-
-
De Smedt, T.1
Vonck, K.2
Raedt, R.3
Dedeurwaerdere, S.4
Claeys, P.5
Legros, B.6
Wyckhuys, T.7
Wadman, W.8
Boon, P.9
-
19
-
-
0023274207
-
Cellular mechanisms of epilepsy: A status report
-
Dichter M.A., and Ayala G.F. Cellular mechanisms of epilepsy: A status report. Science 237 (1987) 157-164
-
(1987)
Science
, vol.237
, pp. 157-164
-
-
Dichter, M.A.1
Ayala, G.F.2
-
21
-
-
0343673858
-
Topiramate as an inhibitor of carbonic anhydrase isoenzymes
-
Dodgson S.J., Shank R.P., and Maryanoff B.E. Topiramate as an inhibitor of carbonic anhydrase isoenzymes. Epilepsia 41 Suppl. 1 (2000) S35-S39
-
(2000)
Epilepsia
, vol.41
, Issue.SUPPL. 1
-
-
Dodgson, S.J.1
Shank, R.P.2
Maryanoff, B.E.3
-
22
-
-
0002304729
-
The effect of tiagabine HCl on extracellular GABA levels in the human hippocampus [abstract]
-
During M., Mattson R., Scheyer R., Rask C., Pierce M., McKelvy J., and Thomas V. The effect of tiagabine HCl on extracellular GABA levels in the human hippocampus [abstract]. Epilepsia 33 Suppl. 3 (1992) 83
-
(1992)
Epilepsia
, vol.33
, Issue.SUPPL. 3
, pp. 83
-
-
During, M.1
Mattson, R.2
Scheyer, R.3
Rask, C.4
Pierce, M.5
McKelvy, J.6
Thomas, V.7
-
23
-
-
0026709603
-
The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats
-
Fink-Jensen A., Suzdak P.D., Swedberg M.D., Judge M.E., Hansen L., and Nielsen P.G. The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats. Eur. J. Pharmacol. 220 (1992) 197-201
-
(1992)
Eur. J. Pharmacol.
, vol.220
, pp. 197-201
-
-
Fink-Jensen, A.1
Suzdak, P.D.2
Swedberg, M.D.3
Judge, M.E.4
Hansen, L.5
Nielsen, P.G.6
-
24
-
-
0029975930
-
The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel
-
Gee N.S., Brown J.P., Dissanayake V.U., Offord J., Thurlow R., and Woodruff G.N. The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel. J. Biol. Chem. 271 (1996) 5768-5776
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5768-5776
-
-
Gee, N.S.1
Brown, J.P.2
Dissanayake, V.U.3
Offord, J.4
Thurlow, R.5
Woodruff, G.N.6
-
25
-
-
33750303042
-
Tiagabine: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Giardina W.J. Tiagabine: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 675-680
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 675-680
-
-
Giardina, W.J.1
-
26
-
-
0034076786
-
Cellular actions of topiramate: Blockade of kainate-evoked inward currents in cultured hippocampal neurons
-
Gibbs III J.W., Sombati S., DeLorenzo R.J., and Coulter D.A. Cellular actions of topiramate: Blockade of kainate-evoked inward currents in cultured hippocampal neurons. Epilepsia 41 Suppl. 1 (2000) S10-S16
-
(2000)
Epilepsia
, vol.41
, Issue.SUPPL. 1
-
-
Gibbs III, J.W.1
Sombati, S.2
DeLorenzo, R.J.3
Coulter, D.A.4
-
27
-
-
0026471112
-
ucb L059, a novel anti-convulsant drug: Pharmacological profile in animals
-
Gower A.J., Noyer M., Verloes R., Gobert J., and Wulfert E. ucb L059, a novel anti-convulsant drug: Pharmacological profile in animals. Eur. J. Pharmacol. 222 (1992) 193-203
-
(1992)
Eur. J. Pharmacol.
, vol.222
, pp. 193-203
-
-
Gower, A.J.1
Noyer, M.2
Verloes, R.3
Gobert, J.4
Wulfert, E.5
-
28
-
-
0028823233
-
Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy
-
Gower A.J., Hirsch E., Boehrer A., Noyer M., and Marescaux C. Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy. Epilepsy Res. 22 (1995) 207-213
-
(1995)
Epilepsy Res.
, vol.22
, pp. 207-213
-
-
Gower, A.J.1
Hirsch, E.2
Boehrer, A.3
Noyer, M.4
Marescaux, C.5
-
29
-
-
0003575617
-
Oxcarbazepine
-
Meldrum B.S., and Porter R.J. (Eds), John Libbey & Co., London
-
Gram L., and Philbert A. Oxcarbazepine. In: Meldrum B.S., and Porter R.J. (Eds). "New Anticonvulsant Drugs" (1986), John Libbey & Co., London 229-235
-
(1986)
"New Anticonvulsant Drugs"
, pp. 229-235
-
-
Gram, L.1
Philbert, A.2
-
30
-
-
33645828611
-
Topiramate and its clinical applications in epilepsy
-
Guerrini R., and Parmeggiani L. Topiramate and its clinical applications in epilepsy. Expert Opin. Pharmacother. 7 (2006) 811-823
-
(2006)
Expert Opin. Pharmacother.
, vol.7
, pp. 811-823
-
-
Guerrini, R.1
Parmeggiani, L.2
-
31
-
-
0033957224
-
Felbamate block of recombinant N-methyl-D-aspartate receptors: Selectivity for the NR2B subunit
-
Harty T.P., and Rogawski M.A. Felbamate block of recombinant N-methyl-D-aspartate receptors: Selectivity for the NR2B subunit. Epilepsy Res. 39 (2000) 47-55
-
(2000)
Epilepsy Res.
, vol.39
, pp. 47-55
-
-
Harty, T.P.1
Rogawski, M.A.2
-
32
-
-
0036171793
-
Two new actions of topiramate: Inhibition of depolarizing GABA(A)-mediated responses and activation of a potassium conductance
-
Herrero A.I., Del Olmo N., Gonzalez-Escalada J.R., and Solis J.M. Two new actions of topiramate: Inhibition of depolarizing GABA(A)-mediated responses and activation of a potassium conductance. Neuropharmacology 42 (2002) 210-220
-
(2002)
Neuropharmacology
, vol.42
, pp. 210-220
-
-
Herrero, A.I.1
Del Olmo, N.2
Gonzalez-Escalada, J.R.3
Solis, J.M.4
-
33
-
-
4143107435
-
Succinimides: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Holland K.D., and Ferrendelli J.A. Succinimides: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 639-645
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 639-645
-
-
Holland, K.D.1
Ferrendelli, J.A.2
-
34
-
-
0015367889
-
The epileptogenic action of Na-folate in the rat
-
Hommes O.R., and Obbens E.A. The epileptogenic action of Na-folate in the rat. J. Neurol. Sci. 16 (1972) 271-281
-
(1972)
J. Neurol. Sci.
, vol.16
, pp. 271-281
-
-
Hommes, O.R.1
Obbens, E.A.2
-
35
-
-
0028907754
-
Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro
-
Honmou O., Kocsis J.D., and Richerson G.B. Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro. Epilepsy Res. 20 (1995) 193-202
-
(1995)
Epilepsy Res.
, vol.20
, pp. 193-202
-
-
Honmou, O.1
Kocsis, J.D.2
Richerson, G.B.3
-
36
-
-
0342358734
-
Oxcarbazepine (GP 47.680): A possible alternative to carbamazepine?
-
Houtkooper M.A., Lammertsma A., Meyer J.W., Goedhart D.M., Meinardi H., van Oorschot C.A., Blom G.F., Hoppener R.J., and Hulsman J.A. Oxcarbazepine (GP 47.680): A possible alternative to carbamazepine?. Epilepsia 28 (1987) 693-698
-
(1987)
Epilepsia
, vol.28
, pp. 693-698
-
-
Houtkooper, M.A.1
Lammertsma, A.2
Meyer, J.W.3
Goedhart, D.M.4
Meinardi, H.5
van Oorschot, C.A.6
Blom, G.F.7
Hoppener, R.J.8
Hulsman, J.A.9
-
38
-
-
0025309183
-
Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons
-
Kelly K.M., Gross R.A., and Macdonald R.L. Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons. Neurosci. Lett. 116 (1990) 233-238
-
(1990)
Neurosci. Lett.
, vol.116
, pp. 233-238
-
-
Kelly, K.M.1
Gross, R.A.2
Macdonald, R.L.3
-
39
-
-
0030035708
-
Mechanisms of T-type calcium channel blockade by zonisamide
-
Kito M., Maehara M., and Watanabe K. Mechanisms of T-type calcium channel blockade by zonisamide. Seizure 5 (1996) 115-119
-
(1996)
Seizure
, vol.5
, pp. 115-119
-
-
Kito, M.1
Maehara, M.2
Watanabe, K.3
-
40
-
-
0028220873
-
Gabapentin increases GABA-induced depolarization in rat neonatal optic nerve
-
Kocsis J.D., and Honmou O. Gabapentin increases GABA-induced depolarization in rat neonatal optic nerve. Neurosci. Lett. 169 (1994) 181-184
-
(1994)
Neurosci. Lett.
, vol.169
, pp. 181-184
-
-
Kocsis, J.D.1
Honmou, O.2
-
42
-
-
16344368695
-
Topiramate inhibits the initiation of plateau potentials in CA1 neurons by depressing R-type calcium channels
-
Kuzmiski J.B., Barr W., Zamponi G.W., and MacVicar B.A. Topiramate inhibits the initiation of plateau potentials in CA1 neurons by depressing R-type calcium channels. Epilepsia 46 (2005) 481-489
-
(2005)
Epilepsia
, vol.46
, pp. 481-489
-
-
Kuzmiski, J.B.1
Barr, W.2
Zamponi, G.W.3
MacVicar, B.A.4
-
43
-
-
0027507511
-
Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells
-
Lang D.G., Wang C.M., and Cooper B.R. Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells. J. Pharmacol. Exp. Ther. 266 (1993) 829-835
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.266
, pp. 829-835
-
-
Lang, D.G.1
Wang, C.M.2
Cooper, B.R.3
-
44
-
-
0022900644
-
Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action
-
Leach M.J., Marden C.M., and Miller A.A. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia 27 (1986) 490-497
-
(1986)
Epilepsia
, vol.27
, pp. 490-497
-
-
Leach, M.J.1
Marden, C.M.2
Miller, A.A.3
-
45
-
-
3242807880
-
Lamotrigine: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Leach M.J., Randall A.D., Stefani A., and Hainsworth A.H. Lamotrigine: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed (2002), Lippincott Williams & Wilkins, Philadelphia 363-369
-
(2002)
"Antiepileptic Drugs". 5th ed
, pp. 363-369
-
-
Leach, M.J.1
Randall, A.D.2
Stefani, A.3
Hainsworth, A.H.4
-
46
-
-
0027310109
-
Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neurological cultures from rat cortex
-
Lees G., and Leach M.J. Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neurological cultures from rat cortex. Brain Res. 612 (1993) 190-199
-
(1993)
Brain Res.
, vol.612
, pp. 190-199
-
-
Lees, G.1
Leach, M.J.2
-
47
-
-
31344471472
-
Basic research in epilepsy and aging
-
Leppik I.E., Kelly K.M., deToledo-Morrell L., Patrylo P.R., DeLorenzo R.J., Mathern G.W., and White H.S. Basic research in epilepsy and aging. Epilepsy Res. 68 Suppl. 1 (2006) S21-S37
-
(2006)
Epilepsy Res.
, vol.68
, Issue.SUPPL. 1
-
-
Leppik, I.E.1
Kelly, K.M.2
deToledo-Morrell, L.3
Patrylo, P.R.4
DeLorenzo, R.J.5
Mathern, G.W.6
White, H.S.7
-
48
-
-
0032125478
-
On the action of the anti-absence drug ethosuximide in the rat and cat thalamus
-
Leresche N., Parri H.R., Erdemli G., Guyon A., Turner J.P., Williams S.R., Asprodini E., and Crunelli V. On the action of the anti-absence drug ethosuximide in the rat and cat thalamus. J. Neurosci. 18 (1998) 4842-4853
-
(1998)
J. Neurosci.
, vol.18
, pp. 4842-4853
-
-
Leresche, N.1
Parri, H.R.2
Erdemli, G.3
Guyon, A.4
Turner, J.P.5
Williams, S.R.6
Asprodini, E.7
Crunelli, V.8
-
49
-
-
0019503690
-
Valproate induced changes in GABA metabolism at the subcellular level
-
Loscher W. Valproate induced changes in GABA metabolism at the subcellular level. Biochem. Pharmacol. 30 (1981) 1364-1366
-
(1981)
Biochem. Pharmacol.
, vol.30
, pp. 1364-1366
-
-
Loscher, W.1
-
50
-
-
4243491268
-
Valproic acid: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Loscher W. Valproic acid: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 767-779
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 767-779
-
-
Loscher, W.1
-
51
-
-
0025764823
-
Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain
-
Loscher W., Honack D., and Taylor C.P. Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain. Neurosci. Lett. 128 (1991) 150-154
-
(1991)
Neurosci. Lett.
, vol.128
, pp. 150-154
-
-
Loscher, W.1
Honack, D.2
Taylor, C.P.3
-
52
-
-
3042748137
-
The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
-
Lynch B.A., Lambeng N., Nocka K., Kensel-Hammes P., Bajjalieh S.M., Matagne A., and Fuks B. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc. Natl. Acad. Sci. USA 101 (2004) 9861-9866
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9861-9866
-
-
Lynch, B.A.1
Lambeng, N.2
Nocka, K.3
Kensel-Hammes, P.4
Bajjalieh, S.M.5
Matagne, A.6
Fuks, B.7
-
53
-
-
0024450953
-
Antiepileptic drug actions
-
discussion S64-S68
-
Macdonald R.L. Antiepileptic drug actions. Epilepsia 30 Suppl. 1 (1989) S19-S28 discussion S64-S68
-
(1989)
Epilepsia
, vol.30
, Issue.SUPPL. 1
-
-
Macdonald, R.L.1
-
54
-
-
1642377949
-
Benzodiazepines: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Macdonald R.L. Benzodiazepines: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). Antiepileptic Drugs. 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 179-186
-
(2002)
Antiepileptic Drugs. 5th ed.
, pp. 179-186
-
-
Macdonald, R.L.1
-
55
-
-
1642377949
-
Carbamazepine: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Macdonald R.L. Carbamazepine: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 227-235
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 227-235
-
-
Macdonald, R.L.1
-
56
-
-
1442344104
-
Zonisamide: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Macdonald R.L. Zonisamide: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 867-872
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 867-872
-
-
Macdonald, R.L.1
-
57
-
-
0029057901
-
Antiepileptic drug mechanisms of action
-
Macdonald R.L., and Kelly K.M. Antiepileptic drug mechanisms of action. Epilepsia 36 Suppl. 2 (1995) S2-S12
-
(1995)
Epilepsia
, vol.36
, Issue.SUPPL. 2
-
-
Macdonald, R.L.1
Kelly, K.M.2
-
59
-
-
0024415567
-
Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture
-
Macdonald R.L., Rogers C.J., and Twyman R.E. Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture. J. Physiol. 417 (1989) 483-500
-
(1989)
J. Physiol.
, vol.417
, pp. 483-500
-
-
Macdonald, R.L.1
Rogers, C.J.2
Twyman, R.E.3
-
60
-
-
0033800837
-
Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs
-
Margineanu D.G., and Klitgaard H. Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs. Pharmacol. Res. 42 (2000) 281-285
-
(2000)
Pharmacol. Res.
, vol.42
, pp. 281-285
-
-
Margineanu, D.G.1
Klitgaard, H.2
-
61
-
-
0002100772
-
Levetiracetam: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Margineanu D.G., and Klitgaard H. Levetiracetam: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 419-427
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 419-427
-
-
Margineanu, D.G.1
Klitgaard, H.2
-
62
-
-
0028784616
-
ucb L059, a novel anticonvulsant, reduces bicuculline-induced hyperexcitability in rat hippocampal CA3 in vivo
-
Margineanu D.G., and Wulfert E. ucb L059, a novel anticonvulsant, reduces bicuculline-induced hyperexcitability in rat hippocampal CA3 in vivo. Eur. J. Pharmacol. 286 (1995) 321-325
-
(1995)
Eur. J. Pharmacol.
, vol.286
, pp. 321-325
-
-
Margineanu, D.G.1
Wulfert, E.2
-
63
-
-
0030734833
-
Inhibition by levetiracetam of a non-GABAA receptor-associated epileptiform effect of bicuculline in rat hippocampus
-
Margineanu D.G., and Wulfert E. Inhibition by levetiracetam of a non-GABAA receptor-associated epileptiform effect of bicuculline in rat hippocampus. Br. J. Pharmacol. 122 (1997) 1146-1150
-
(1997)
Br. J. Pharmacol.
, vol.122
, pp. 1146-1150
-
-
Margineanu, D.G.1
Wulfert, E.2
-
64
-
-
0021887675
-
Com- parison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures
-
Mattson R.H., Cramer J.A., Collins J.F., Smith D.B., Delgado-Escueta A.V., Browne T.R., Williamson P.D., Treiman D.M., McNamara J.O., McCutchen C.B., et al. Com- parison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. N. Engl. J. Med. 313 (1985) 145-151
-
(1985)
N. Engl. J. Med.
, vol.313
, pp. 145-151
-
-
Mattson, R.H.1
Cramer, J.A.2
Collins, J.F.3
Smith, D.B.4
Delgado-Escueta, A.V.5
Browne, T.R.6
Williamson, P.D.7
Treiman, D.M.8
McNamara, J.O.9
McCutchen, C.B.10
-
65
-
-
0027381484
-
Evidence for anticonvulsant and neuroprotectant action of felbamate mediated by strychnine-insensitive glycine receptors
-
McCabe R.T., Wasterlain C.G., Kucharczyk N., Sofia R.D., and Vogel J.R. Evidence for anticonvulsant and neuroprotectant action of felbamate mediated by strychnine-insensitive glycine receptors. J. Pharmacol. Exp. Ther. 264 (1993) 1248-1252
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.264
, pp. 1248-1252
-
-
McCabe, R.T.1
Wasterlain, C.G.2
Kucharczyk, N.3
Sofia, R.D.4
Vogel, J.R.5
-
66
-
-
0042395138
-
Oxcarbazepine: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
McLean M.J. Oxcarbazepine: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 451-458
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 451-458
-
-
McLean, M.J.1
-
67
-
-
0022516644
-
Carbamazepine and 10,11-epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture
-
McLean M.J., and Macdonald R.L. Carbamazepine and 10,11-epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture. J. Pharmacol. Exp. Ther. 238 (1986) 727-738
-
(1986)
J. Pharmacol. Exp. Ther.
, vol.238
, pp. 727-738
-
-
McLean, M.J.1
Macdonald, R.L.2
-
68
-
-
0022540479
-
Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture
-
McLean M.J., and Macdonald R.L. Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture. J. Pharmacol. Exp. Ther. 237 (1986) 1001-1011
-
(1986)
J. Pharmacol. Exp. Ther.
, vol.237
, pp. 1001-1011
-
-
McLean, M.J.1
Macdonald, R.L.2
-
69
-
-
0028269416
-
Oxcarbazepine: Mechanisms of action
-
McLean M.J., Schmutz M., Wamil A.W., Olpe H.R., Portet C., and Feldmann K.F. Oxcarbazepine: Mechanisms of action. Epilepsia 35 Suppl. 3 (1994) S5-S9
-
(1994)
Epilepsia
, vol.35
, Issue.SUPPL. 3
-
-
McLean, M.J.1
Schmutz, M.2
Wamil, A.W.3
Olpe, H.R.4
Portet, C.5
Feldmann, K.F.6
-
70
-
-
0034040285
-
Effects of topiramate on sodium-dependent action-potential firing by mouse spinal cord neurons in cell culture
-
McLean M.J., Bukhari A.A., and Wamil A.W. Effects of topiramate on sodium-dependent action-potential firing by mouse spinal cord neurons in cell culture. Epilepsia 41 Suppl. 1 (2000) S21-S24
-
(2000)
Epilepsia
, vol.41
, Issue.SUPPL. 1
-
-
McLean, M.J.1
Bukhari, A.A.2
Wamil, A.W.3
-
71
-
-
0030323503
-
Action of established and novel anticonvulsant drugs on the basic mechanisms of epilepsy
-
Meldrum B. Action of established and novel anticonvulsant drugs on the basic mechanisms of epilepsy. Epilepsy Res. Suppl. 11 (1996) 67-77
-
(1996)
Epilepsy Res. Suppl.
, vol.11
, pp. 67-77
-
-
Meldrum, B.1
-
72
-
-
0032473367
-
Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
-
Michaelis E.K. Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging. Prog. Neurobiol. 54 (1998) 369-415
-
(1998)
Prog. Neurobiol.
, vol.54
, pp. 369-415
-
-
Michaelis, E.K.1
-
73
-
-
33746217426
-
Pregabalin reduces the release of synaptic vesicles from cultured hippocampal neurons
-
Micheva K.D., Taylor C.P., and Smith S.J. Pregabalin reduces the release of synaptic vesicles from cultured hippocampal neurons. Mol. Pharmacol. 70 (2006) 467-476
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 467-476
-
-
Micheva, K.D.1
Taylor, C.P.2
Smith, S.J.3
-
74
-
-
0023823852
-
[3H]Zonisamide binding in rat brain
-
Mimaki T., Suzuki Y., Tagawa T., Tanaka J., Itoh N., and Yabuuchi H. [3H]Zonisamide binding in rat brain. Jpn. J. Psychiatry Neurol. 42 3 (1988) 640-642
-
(1988)
Jpn. J. Psychiatry Neurol.
, vol.42
, Issue.3
, pp. 640-642
-
-
Mimaki, T.1
Suzuki, Y.2
Tagawa, T.3
Tanaka, J.4
Itoh, N.5
Yabuuchi, H.6
-
75
-
-
0025405649
-
Interaction of zonisamide with benzodiazepine and GABA receptors in rat brain
-
Mimaki T., Suzuki Y., Tagawa T., Karasawa T., and Yabuuchi H. Interaction of zonisamide with benzodiazepine and GABA receptors in rat brain. Med. J. Osaka Univ. 39 (1990) 13-17
-
(1990)
Med. J. Osaka Univ.
, vol.39
, pp. 13-17
-
-
Mimaki, T.1
Suzuki, Y.2
Tagawa, T.3
Karasawa, T.4
Yabuuchi, H.5
-
76
-
-
0035164999
-
Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action
-
Ng G.Y., Bertrand S., Sullivan R., Ethier N., Wang J., Yergey J., Belley M., Trimble L., Bateman K., Alder L., Smith A., McKernan R., et al. Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action. Mol. Pharmacol. 59 (2001) 144-152
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 144-152
-
-
Ng, G.Y.1
Bertrand, S.2
Sullivan, R.3
Ethier, N.4
Wang, J.5
Yergey, J.6
Belley, M.7
Trimble, L.8
Bateman, K.9
Alder, L.10
Smith, A.11
McKernan, R.12
-
77
-
-
0035933671
-
Levetiracetam inhibits the high-voltage-activated Ca(2+) current in pyramidal neurones of rat hippocampal slices
-
Niespodziany I., Klitgaard H., and Margineanu D.G. Levetiracetam inhibits the high-voltage-activated Ca(2+) current in pyramidal neurones of rat hippocampal slices. Neurosci. Lett. 306 (2001) 5-8
-
(2001)
Neurosci. Lett.
, vol.306
, pp. 5-8
-
-
Niespodziany, I.1
Klitgaard, H.2
Margineanu, D.G.3
-
78
-
-
0036763717
-
Characteristics and indications of topiramate
-
Nieto-Barrera M. Characteristics and indications of topiramate. Rev. Neurol. 35 Suppl. 1 (2002) S88-S95
-
(2002)
Rev. Neurol.
, vol.35
, Issue.SUPPL. 1
-
-
Nieto-Barrera, M.1
-
79
-
-
0028825031
-
The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes
-
Noyer M., Gillard M., Matagne A., Henichart J.P., and Wulfert E. The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes. Eur. J. Pharmacol. 286 (1995) 137-146
-
(1995)
Eur. J. Pharmacol.
, vol.286
, pp. 137-146
-
-
Noyer, M.1
Gillard, M.2
Matagne, A.3
Henichart, J.P.4
Wulfert, E.5
-
80
-
-
8344264314
-
Phenobarbital and other barbiturates: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Olsen R.W. Phenobarbital and other barbiturates: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 489-495
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 489-495
-
-
Olsen, R.W.1
-
81
-
-
3042841014
-
Gabapentin activates presynaptic GABAB heteroreceptors in rat cortical slices
-
Parker D.A., Ong J., Marino V., and Kerr D.I. Gabapentin activates presynaptic GABAB heteroreceptors in rat cortical slices. Eur. J. Pharmacol. 495 (2004) 137-143
-
(2004)
Eur. J. Pharmacol.
, vol.495
, pp. 137-143
-
-
Parker, D.A.1
Ong, J.2
Marino, V.3
Kerr, D.I.4
-
82
-
-
0031467511
-
Felbamate: 1997 update
-
Pellock J.M., and Brodie M.J. Felbamate: 1997 update. Epilepsia 38 (1997) 1261-1264
-
(1997)
Epilepsia
, vol.38
, pp. 1261-1264
-
-
Pellock, J.M.1
Brodie, M.J.2
-
83
-
-
0038821615
-
Felbamate
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Pellock J.M., Perhach J.L., and Sofia R.D. Felbamate. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 301-318
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 301-318
-
-
Pellock, J.M.1
Perhach, J.L.2
Sofia, R.D.3
-
84
-
-
0342759370
-
Gabapentin increases brain gama-aminobutyric acid levels in patients with epilepsy [abstract]
-
Abstract M46
-
Petroff O.A.C., Rothman D.L., Behar K.L., Lamoureax D., and Mattson R.H. Gabapentin increases brain gama-aminobutyric acid levels in patients with epilepsy [abstract]. Ann. Neurol. 38 (1995) 295-296 Abstract M46
-
(1995)
Ann. Neurol.
, vol.38
, pp. 295-296
-
-
Petroff, O.A.C.1
Rothman, D.L.2
Behar, K.L.3
Lamoureax, D.4
Mattson, R.H.5
-
86
-
-
0021996795
-
Effect of stimulus intensity on the profile of anticonvulsant activity of phenytoin, ethosuximide and valproate
-
Piredda S.G., Woodhead J.H., and Swinyard E.A. Effect of stimulus intensity on the profile of anticonvulsant activity of phenytoin, ethosuximide and valproate. J. Pharmacol. Exp. Ther. 232 (1985) 741-745
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.232
, pp. 741-745
-
-
Piredda, S.G.1
Woodhead, J.H.2
Swinyard, E.A.3
-
87
-
-
0029127734
-
Electrophysiological actions of felbamate on rat striatal neurones
-
Pisani A., Stefani A., Siniscalchi A., Mercuri N.B., Bernardi G., and Calabresi P. Electrophysiological actions of felbamate on rat striatal neurones. Br. J. Pharmacol. 116 (1995) 2053-2061
-
(1995)
Br. J. Pharmacol.
, vol.116
, pp. 2053-2061
-
-
Pisani, A.1
Stefani, A.2
Siniscalchi, A.3
Mercuri, N.B.4
Bernardi, G.5
Calabresi, P.6
-
88
-
-
37049223719
-
Experimental determination of the anticonvulsant properties of some phenyl derivatives
-
Putnam T.J., and Merritt H.H. Experimental determination of the anticonvulsant properties of some phenyl derivatives. Science 85 (1937) 525-526
-
(1937)
Science
, vol.85
, pp. 525-526
-
-
Putnam, T.J.1
Merritt, H.H.2
-
89
-
-
0021036376
-
Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: Are there common or different sites of action?
-
Reimann W. Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: Are there common or different sites of action?. Eur. J. Pharmacol. 94 (1983) 341-344
-
(1983)
Eur. J. Pharmacol.
, vol.94
, pp. 341-344
-
-
Reimann, W.1
-
90
-
-
0023629575
-
Comparison of oxcarbazepine and carbamazepine: A double-blind study
-
Reinikainen K.J., Keranen T., Halonen T., Komulainen H., and Riekkinen P.J. Comparison of oxcarbazepine and carbamazepine: A double-blind study. Epilepsy Res. 1 (1987) 284-289
-
(1987)
Epilepsy Res.
, vol.1
, pp. 284-289
-
-
Reinikainen, K.J.1
Keranen, T.2
Halonen, T.3
Komulainen, H.4
Riekkinen, P.J.5
-
91
-
-
0025060943
-
The effect of two lipophilic gamma-aminobutyric acid uptake blockers in CA1 of the rat hippocampal slice
-
Rekling J.C., Jahnsen H., and Mosfeldt Laursen A. The effect of two lipophilic gamma-aminobutyric acid uptake blockers in CA1 of the rat hippocampal slice. Br. J. Pharmacol. 99 (1990) 103-106
-
(1990)
Br. J. Pharmacol.
, vol.99
, pp. 103-106
-
-
Rekling, J.C.1
Jahnsen, H.2
Mosfeldt Laursen, A.3
-
92
-
-
0013981376
-
Anticonvulsant therapy, folic acid and vitamin B12 metabolism and mental symptoms
-
Reynolds E.H., Chanarin I., Milner G., and Matthews D.M. Anticonvulsant therapy, folic acid and vitamin B12 metabolism and mental symptoms. Epilepsia 7 (1966) 261-270
-
(1966)
Epilepsia
, vol.7
, pp. 261-270
-
-
Reynolds, E.H.1
Chanarin, I.2
Milner, G.3
Matthews, D.M.4
-
93
-
-
0032730181
-
The pharmacologic basis of antiepileptic drug action
-
Rho J.M., and Sankar R. The pharmacologic basis of antiepileptic drug action. Epilepsia 40 (1999) 1471-1483
-
(1999)
Epilepsia
, vol.40
, pp. 1471-1483
-
-
Rho, J.M.1
Sankar, R.2
-
94
-
-
0028008995
-
Mechanism of action of the anticonvulsant felbamate: Opposing effects on N-methyl-D-aspartate and gamma-aminobutyric acidA receptors
-
Rho J.M., Donevan S.D., and Rogawski M.A. Mechanism of action of the anticonvulsant felbamate: Opposing effects on N-methyl-D-aspartate and gamma-aminobutyric acidA receptors. Ann. Neurol. 35 (1994) 229-234
-
(1994)
Ann. Neurol.
, vol.35
, pp. 229-234
-
-
Rho, J.M.1
Donevan, S.D.2
Rogawski, M.A.3
-
95
-
-
34047237123
-
Correlation of inhibition of veratrine evoked [14C] guanidine uptake with inhibition of veratrine evoked release of glutamate by lamotrigine and its analogues [abstract]
-
Abstract 6-11-17
-
Riddall D.R., Clackers M., and Leach M.J. Correlation of inhibition of veratrine evoked [14C] guanidine uptake with inhibition of veratrine evoked release of glutamate by lamotrigine and its analogues [abstract]. Can. J. Neurol. Sci. 20 Suppl. 4 (1993) S181 Abstract 6-11-17
-
(1993)
Can. J. Neurol. Sci.
, vol.20
, Issue.SUPPL. 4
-
-
Riddall, D.R.1
Clackers, M.2
Leach, M.J.3
-
96
-
-
0035987775
-
The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents
-
Rigo J.M., Hans G., Nguyen L., Rocher V., Belachew S., Malgrange B., Leprince P., Moonen G., Selak I., Matagne A., and Klitgaard H. The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents. Br. J. Pharmacol. 136 (2002) 659-672
-
(2002)
Br. J. Pharmacol.
, vol.136
, pp. 659-672
-
-
Rigo, J.M.1
Hans, G.2
Nguyen, L.3
Rocher, V.4
Belachew, S.5
Malgrange, B.6
Leprince, P.7
Moonen, G.8
Selak, I.9
Matagne, A.10
Klitgaard, H.11
-
97
-
-
0024593140
-
Blockade of sustained repetitive action potentials in cultured spinal cord neurons by zonisamide (AD 810, CI 912), a novel anticonvulsant
-
Rock D.M., Macdonald R.L., and Taylor C.P. Blockade of sustained repetitive action potentials in cultured spinal cord neurons by zonisamide (AD 810, CI 912), a novel anticonvulsant. Epilepsy Res. 3 (1989) 138-143
-
(1989)
Epilepsy Res.
, vol.3
, pp. 138-143
-
-
Rock, D.M.1
Macdonald, R.L.2
Taylor, C.P.3
-
98
-
-
0026447816
-
Comparison of the effect of the GABA uptake blockers, tiagabine and nipecotic acid, on inhibitory synaptic efficacy in hippocampal CA1 neurones
-
Roepstorff A., and Lambert J.D. Comparison of the effect of the GABA uptake blockers, tiagabine and nipecotic acid, on inhibitory synaptic efficacy in hippocampal CA1 neurones. Neurosci. Lett. 146 (1992) 131-134
-
(1992)
Neurosci. Lett.
, vol.146
, pp. 131-134
-
-
Roepstorff, A.1
Lambert, J.D.2
-
99
-
-
30144443464
-
Molecular targets versus models for new antiepileptic drug discovery
-
Rogawski M.A. Molecular targets versus models for new antiepileptic drug discovery. Epilepsy Res. 68 (2006) 22-28
-
(2006)
Epilepsy Res.
, vol.68
, pp. 22-28
-
-
Rogawski, M.A.1
-
100
-
-
0025050694
-
Antiepileptic drugs: Pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds
-
Rogawski M.A., and Porter R.J. Antiepileptic drugs: Pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds. Pharmacol. Rev. 42 (1990) 223-286
-
(1990)
Pharmacol. Rev.
, vol.42
, pp. 223-286
-
-
Rogawski, M.A.1
Porter, R.J.2
-
101
-
-
0028181698
-
Benzodiazepine and beta-carboline regulation of single GABAA receptor channels of mouse spinal neurones in culture
-
Rogers C.J., Twyman R.E., and Macdonald R.L. Benzodiazepine and beta-carboline regulation of single GABAA receptor channels of mouse spinal neurones in culture. J. Physiol. 475 (1994) 69-82
-
(1994)
J. Physiol.
, vol.475
, pp. 69-82
-
-
Rogers, C.J.1
Twyman, R.E.2
Macdonald, R.L.3
-
102
-
-
0026788484
-
An assessment of serum and red blood cell folate concentrations in patients with epilepsy on lamotrigine therapy
-
Sander J.W., and Patsalos P.N. An assessment of serum and red blood cell folate concentrations in patients with epilepsy on lamotrigine therapy. Epilepsy Res. 13 (1992) 89-92
-
(1992)
Epilepsy Res.
, vol.13
, pp. 89-92
-
-
Sander, J.W.1
Patsalos, P.N.2
-
103
-
-
0023186374
-
Zonisamide enhances slow sodium inactivation in Myxicola
-
Schauf C.L. Zonisamide enhances slow sodium inactivation in Myxicola. Brain Res. 413 (1987) 185-188
-
(1987)
Brain Res.
, vol.413
, pp. 185-188
-
-
Schauf, C.L.1
-
104
-
-
0002368059
-
Potential antiepileptic drugs: Gabapentin
-
Levy R., Mattson R., Meldrum B., Penry J.K., and Dreifuss F.E. (Eds), Raven Press, New York
-
Schmidt B. Potential antiepileptic drugs: Gabapentin. In: Levy R., Mattson R., Meldrum B., Penry J.K., and Dreifuss F.E. (Eds). "Antiepileptic Drugs". 3rd ed. (1989), Raven Press, New York 925-935
-
(1989)
"Antiepileptic Drugs". 3rd ed.
, pp. 925-935
-
-
Schmidt, B.1
-
105
-
-
0000946466
-
GP 47779, the main human metabolite of oxcarbazepine (Trileptal), and both enantiomers have equal anticonvulsant activity [abstract]
-
Schmutz M., Ferrat T., Heckendorn R., Jeker A., Portet C., and Olpe H.R. GP 47779, the main human metabolite of oxcarbazepine (Trileptal), and both enantiomers have equal anticonvulsant activity [abstract]. Epilepsia 34 Suppl. 2 (1993) 122
-
(1993)
Epilepsia
, vol.34
, Issue.SUPPL. 2
, pp. 122
-
-
Schmutz, M.1
Ferrat, T.2
Heckendorn, R.3
Jeker, A.4
Portet, C.5
Olpe, H.R.6
-
106
-
-
0024372376
-
Phenytoin and carbamazepine: Potential- and frequency-dependent block of Na currents in mammalian myelinated nerve fibers
-
Schwarz J.R., and Grigat G. Phenytoin and carbamazepine: Potential- and frequency-dependent block of Na currents in mammalian myelinated nerve fibers. Epilepsia 30 (1989) 286-294
-
(1989)
Epilepsia
, vol.30
, pp. 286-294
-
-
Schwarz, J.R.1
Grigat, G.2
-
107
-
-
0002007589
-
Other antiepileptic drugs. Zonisamide
-
Levy R.H., Mattson R.H., and Meldrum B.S. (Eds), Raven Press Ltd., New York
-
Seino M., Naruto S., Ito T., and Miyazaki H. Other antiepileptic drugs. Zonisamide. In: Levy R.H., Mattson R.H., and Meldrum B.S. (Eds). "Antiepileptic Drugs". 4th ed. (1995), Raven Press Ltd., New York 1011-1023
-
(1995)
"Antiepileptic Drugs". 4th ed.
, pp. 1011-1023
-
-
Seino, M.1
Naruto, S.2
Ito, T.3
Miyazaki, H.4
-
108
-
-
0002836371
-
Topiramate selectively blocks kainate currents in cultured hippocampal neurons [abstract]
-
Abstract 2.16
-
Severt L., Coulter D.A., Sombati S., and DeLorenzo R.J. Topiramate selectively blocks kainate currents in cultured hippocampal neurons [abstract]. Epilepsia 36 Suppl. 4 (1995) 38 Abstract 2.16
-
(1995)
Epilepsia
, vol.36
, Issue.SUPPL. 4
, pp. 38
-
-
Severt, L.1
Coulter, D.A.2
Sombati, S.3
DeLorenzo, R.J.4
-
109
-
-
0028221989
-
Topiramate: Preclinical evaluation of a structurally novel anticonvulsant
-
Shank R.P., Gardocki J.F., Vaught J.L., Davis C.B., Schupsky J.J., Raffa R.B., Dodgson S.J., Nortey S.O., and Maryanoff B.E. Topiramate: Preclinical evaluation of a structurally novel anticonvulsant. Epilepsia 35 (1994) 450-460
-
(1994)
Epilepsia
, vol.35
, pp. 450-460
-
-
Shank, R.P.1
Gardocki, J.F.2
Vaught, J.L.3
Davis, C.B.4
Schupsky, J.J.5
Raffa, R.B.6
Dodgson, S.J.7
Nortey, S.O.8
Maryanoff, B.E.9
-
110
-
-
0034034180
-
An overview of the preclinical aspects of topiramate: Pharmacology, pharmacokinetics, and mechanism of action
-
Shank R.P., Gardocki J.F., Streeter A.J., and Maryanoff B.E. An overview of the preclinical aspects of topiramate: Pharmacology, pharmacokinetics, and mechanism of action. Epilepsia 41 Suppl. 1 (2000) S3-S9
-
(2000)
Epilepsia
, vol.41
, Issue.SUPPL. 1
-
-
Shank, R.P.1
Gardocki, J.F.2
Streeter, A.J.3
Maryanoff, B.E.4
-
111
-
-
17244370036
-
Direct activation of the recombinant α4β3γ2S GABAA receptor by the novel anticonvulsant topiramate
-
Simeone T.A., McClellan A.M.L., Twyman R.E., and White H.S. Direct activation of the recombinant α4β3γ2S GABAA receptor by the novel anticonvulsant topiramate. Soc. Neurosci. Abstr. 26 (2000) 631
-
(2000)
Soc. Neurosci. Abstr.
, vol.26
, pp. 631
-
-
Simeone, T.A.1
McClellan, A.M.L.2
Twyman, R.E.3
White, H.S.4
-
112
-
-
33646693680
-
Subunit selectivity of topiramate modulation of heteromeric GABA(A) receptors
-
Simeone T.A., Wilcox K.S., and White H.S. Subunit selectivity of topiramate modulation of heteromeric GABA(A) receptors. Neuropharmacology 50 (2006) 845-857
-
(2006)
Neuropharmacology
, vol.50
, pp. 845-857
-
-
Simeone, T.A.1
Wilcox, K.S.2
White, H.S.3
-
113
-
-
0034115767
-
Topiramate blocks kainate-evoked cobalt influx into cultured neurons
-
Skradski S., and White H.S. Topiramate blocks kainate-evoked cobalt influx into cultured neurons. Epilepsia 41 Suppl. 1 (2000) S45-S47
-
(2000)
Epilepsia
, vol.41
, Issue.SUPPL. 1
-
-
Skradski, S.1
White, H.S.2
-
114
-
-
0002650306
-
Felbamate. Mechanisms of action
-
Levy R.H., Mattson R.H., and Meldrum B.S. (Eds), Raven Press Ltd., New York
-
Sofia R.D. Felbamate. Mechanisms of action. In: Levy R.H., Mattson R.H., and Meldrum B.S. (Eds). "Antiepileptic Drugs". 4th ed. (1995), Raven Press Ltd., New York 791-797
-
(1995)
"Antiepileptic Drugs". 4th ed.
, pp. 791-797
-
-
Sofia, R.D.1
-
115
-
-
0029082313
-
Action of GP 47779, the active metabolite of oxcarbazepine, on the corticostriatal system. II. Modulation of high-voltage-activated calcium currents
-
Stefani A., Pisani A., De Murtas M., Mercuri N.B., Marciani M.G., and Calabresi P. Action of GP 47779, the active metabolite of oxcarbazepine, on the corticostriatal system. II. Modulation of high-voltage-activated calcium currents. Epilepsia 36 (1995) 997-1002
-
(1995)
Epilepsia
, vol.36
, pp. 997-1002
-
-
Stefani, A.1
Pisani, A.2
De Murtas, M.3
Mercuri, N.B.4
Marciani, M.G.5
Calabresi, P.6
-
116
-
-
0030594562
-
Lamotrigine inhibits Ca2+ currents in cortical neurons: Functional implications
-
Stefani A., Spadoni F., Siniscalchi A., and Bernardi G. Lamotrigine inhibits Ca2+ currents in cortical neurons: Functional implications. Eur. J. Pharmacol. 307 (1996) 113-116
-
(1996)
Eur. J. Pharmacol.
, vol.307
, pp. 113-116
-
-
Stefani, A.1
Spadoni, F.2
Siniscalchi, A.3
Bernardi, G.4
-
117
-
-
0030848858
-
Voltage-activated calcium channels: Targets of antiepileptic drug therapy?
-
Stefani A., Spadoni F., and Bernardi G. Voltage-activated calcium channels: Targets of antiepileptic drug therapy?. Epilepsia 38 (1997) 959-965
-
(1997)
Epilepsia
, vol.38
, pp. 959-965
-
-
Stefani, A.1
Spadoni, F.2
Bernardi, G.3
-
118
-
-
0031809165
-
Gabapentin inhibits calcium currents in isolated rat brain neurons
-
Stefani A., Spadoni F., and Bernardi G. Gabapentin inhibits calcium currents in isolated rat brain neurons. Neuropharmacology 37 (1998) 83-91
-
(1998)
Neuropharmacology
, vol.37
, pp. 83-91
-
-
Stefani, A.1
Spadoni, F.2
Bernardi, G.3
-
119
-
-
0033003368
-
The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor activation
-
Stringer J.L., and Lorenzo N. The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor activation. Epilepsy Res. 33 (1999) 169-176
-
(1999)
Epilepsy Res.
, vol.33
, pp. 169-176
-
-
Stringer, J.L.1
Lorenzo, N.2
-
120
-
-
0019638379
-
Diazepam and (-)-pentobarbital: Fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons
-
Study R.E., and Barker J.L. Diazepam and (-)-pentobarbital: Fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons. Proc. Natl. Acad. Sci. USA 78 (1981) 7180-7184
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 7180-7184
-
-
Study, R.E.1
Barker, J.L.2
-
121
-
-
0029027873
-
Felbamate block of the N-methyl-D-aspartate receptor
-
Subramaniam S., Rho J.M., Penix L., Donevan S.D., Fielding R.P., and Rogawski M.A. Felbamate block of the N-methyl-D-aspartate receptor. J. Pharmacol. Exp. Ther. 273 (1995) 878-886
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.273
, pp. 878-886
-
-
Subramaniam, S.1
Rho, J.M.2
Penix, L.3
Donevan, S.D.4
Fielding, R.P.5
Rogawski, M.A.6
-
122
-
-
0027916864
-
Characterisation of [3H]gabapentin binding to a novel site in rat brain: Homogenate binding studies
-
Suman-Chauhan N., Webdale L., Hill D.R., and Woodruff G.N. Characterisation of [3H]gabapentin binding to a novel site in rat brain: Homogenate binding studies. Eur. J. Pharmacol. 244 (1993) 293-301
-
(1993)
Eur. J. Pharmacol.
, vol.244
, pp. 293-301
-
-
Suman-Chauhan, N.1
Webdale, L.2
Hill, D.R.3
Woodruff, G.N.4
-
123
-
-
0028999957
-
A review of the preclinical pharmacology of tiagabine: A potent and selective anticonvulsant GABA uptake inhibitor
-
Suzdak P.D., and Jansen J.A. A review of the preclinical pharmacology of tiagabine: A potent and selective anticonvulsant GABA uptake inhibitor. Epilepsia 36 (1995) 612-626
-
(1995)
Epilepsia
, vol.36
, pp. 612-626
-
-
Suzdak, P.D.1
Jansen, J.A.2
-
124
-
-
0026643459
-
Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex
-
Suzuki S., Kawakami K., Nishimura S., Watanabe Y., Yagi K., Seino M., and Miyamoto K. Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex. Epilepsy Res. 12 (1992) 21-27
-
(1992)
Epilepsy Res.
, vol.12
, pp. 21-27
-
-
Suzuki, S.1
Kawakami, K.2
Nishimura, S.3
Watanabe, Y.4
Yagi, K.5
Seino, M.6
Miyamoto, K.7
-
125
-
-
0022627469
-
Comparative anticonvulsant activity and neurotoxicity of felbamate and four prototype antiepileptic drugs in mice and rats
-
Swinyard E.A., Sofia R.D., and Kupferberg H.J. Comparative anticonvulsant activity and neurotoxicity of felbamate and four prototype antiepileptic drugs in mice and rats. Epilepsia 27 (1986) 27-34
-
(1986)
Epilepsia
, vol.27
, pp. 27-34
-
-
Swinyard, E.A.1
Sofia, R.D.2
Kupferberg, H.J.3
-
126
-
-
0030571493
-
Felbamate inhibits cloned voltage-dependent Na+ channels from human and rat brain
-
Taglialatela M., Ongini E., Brown A.M., Di Renzo G., and Annunziato L. Felbamate inhibits cloned voltage-dependent Na+ channels from human and rat brain. Eur. J. Pharmacol. 316 (1996) 373-377
-
(1996)
Eur. J. Pharmacol.
, vol.316
, pp. 373-377
-
-
Taglialatela, M.1
Ongini, E.2
Brown, A.M.3
Di Renzo, G.4
Annunziato, L.5
-
128
-
-
0038144920
-
Gabapentin: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
Taylor C.P. Gabapentin: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 321-334
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 321-334
-
-
Taylor, C.P.1
-
129
-
-
0031883542
-
A summary of mechanistic hypotheses of gabapentin pharmacology
-
Taylor C.P., Gee N.S., Su T.Z., Kocsis J.D., Welty D.F., Brown J.P., Dooley D.J., Boden P., and Singh L. A summary of mechanistic hypotheses of gabapentin pharmacology. Epilepsy Res. 29 (1998) 233-249
-
(1998)
Epilepsy Res.
, vol.29
, pp. 233-249
-
-
Taylor, C.P.1
Gee, N.S.2
Su, T.Z.3
Kocsis, J.D.4
Welty, D.F.5
Brown, J.P.6
Dooley, D.J.7
Boden, P.8
Singh, L.9
-
130
-
-
0026771403
-
Effects of the GABA uptake inhibitor tiagabine on inhibitory synaptic potentials in rat hippocampal slice cultures
-
Thompson S.M., and Gahwiler B.H. Effects of the GABA uptake inhibitor tiagabine on inhibitory synaptic potentials in rat hippocampal slice cultures. J. Neurophysiol. 67 (1992) 1698-1701
-
(1992)
J. Neurophysiol.
, vol.67
, pp. 1698-1701
-
-
Thompson, S.M.1
Gahwiler, B.H.2
-
131
-
-
0027332638
-
[3H]gabapentin may label a system-L-like neutral amino acid carrier in brain
-
Thurlow R.J., Brown J.P., Gee N.S., Hill D.R., and Woodruff G.N. [3H]gabapentin may label a system-L-like neutral amino acid carrier in brain. Eur. J. Pharmacol. 247 (1993) 341-345
-
(1993)
Eur. J. Pharmacol.
, vol.247
, pp. 341-345
-
-
Thurlow, R.J.1
Brown, J.P.2
Gee, N.S.3
Hill, D.R.4
Woodruff, G.N.5
-
132
-
-
0025913690
-
Effect of anticonvulsant felbamate on GABAA receptor system
-
Ticku M.K., Kamatchi G.L., and Sofia R.D. Effect of anticonvulsant felbamate on GABAA receptor system. Epilepsia 32 (1991) 389-391
-
(1991)
Epilepsia
, vol.32
, pp. 389-391
-
-
Ticku, M.K.1
Kamatchi, G.L.2
Sofia, R.D.3
-
133
-
-
0026739945
-
Modulatory role of GABA receptor subtypes and glutamate receptors in the anticonvulsant effect of barbiturates
-
Ticku M.K., Kulkarni S.K., and Mehta A.K. Modulatory role of GABA receptor subtypes and glutamate receptors in the anticonvulsant effect of barbiturates. Epilepsy Res. Suppl. 8 (1992) 57-62
-
(1992)
Epilepsy Res. Suppl.
, vol.8
, pp. 57-62
-
-
Ticku, M.K.1
Kulkarni, S.K.2
Mehta, A.K.3
-
134
-
-
0024522273
-
Sodium channels from human brain RNA expressed in Xenopus oocytes. Basic electrophysiologic characteristics and their modification by diphenylhydantoin
-
Tomaselli G.F., Marban E., and Yellen G. Sodium channels from human brain RNA expressed in Xenopus oocytes. Basic electrophysiologic characteristics and their modification by diphenylhydantoin. J. Clin. Invest. 83 (1989) 1724-1732
-
(1989)
J. Clin. Invest.
, vol.83
, pp. 1724-1732
-
-
Tomaselli, G.F.1
Marban, E.2
Yellen, G.3
-
135
-
-
0024549518
-
Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital
-
Twyman R.E., Rogers C.J., and Macdonald R.L. Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital. Ann. Neurol. 25 (1989) 213-220
-
(1989)
Ann. Neurol.
, vol.25
, pp. 213-220
-
-
Twyman, R.E.1
Rogers, C.J.2
Macdonald, R.L.3
-
136
-
-
0027223365
-
Valproate and sodium currents in cultured hippocampal neurons
-
Van den Berg R.J., Kok P., and Voskuyl R.A. Valproate and sodium currents in cultured hippocampal neurons. Exp. Brain Res. 93 (1993) 279-287
-
(1993)
Exp. Brain Res.
, vol.93
, pp. 279-287
-
-
Van den Berg, R.J.1
Kok, P.2
Voskuyl, R.A.3
-
137
-
-
0022530225
-
Valproate reduces excitability by blockage of sodium and potassium conductance
-
VanDongen A.M., VanErp M.G., and Voskuyl R.A. Valproate reduces excitability by blockage of sodium and potassium conductance. Epilepsia 27 (1986) 177-182
-
(1986)
Epilepsia
, vol.27
, pp. 177-182
-
-
VanDongen, A.M.1
VanErp, M.G.2
Voskuyl, R.A.3
-
138
-
-
33644531266
-
Activity profile of pregabalin in rodent models of epilepsy and ataxia
-
Vartanian M.G., Radulovic L.L., Kinsora J.J., Serpa K.A., Vergnes M., Bertram E., and Taylor C.P. Activity profile of pregabalin in rodent models of epilepsy and ataxia. Epilepsy Res. 68 (2006) 189-205
-
(2006)
Epilepsy Res.
, vol.68
, pp. 189-205
-
-
Vartanian, M.G.1
Radulovic, L.L.2
Kinsora, J.J.3
Serpa, K.A.4
Vergnes, M.5
Bertram, E.6
Taylor, C.P.7
-
139
-
-
0023600780
-
- channels recorded from membrane patches of neonatal rat cortical neurons in culture
-
- channels recorded from membrane patches of neonatal rat cortical neurons in culture. J. Pharmacol. Exp. Ther. 243 (1987) 1195-1201
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.243
, pp. 1195-1201
-
-
Vicini, S.1
Mienville, J.M.2
Costa, E.3
-
140
-
-
0024368757
-
Effects of chlordiazepoxide, chlorpromazine, diazepam, diphenylhydantoin, flunitrazepam and haloperidol on the voltage-dependent sodium current of isolated mammalian brain neurons
-
Wakamori M., Kaneda M., Oyama Y., and Akaike N. Effects of chlordiazepoxide, chlorpromazine, diazepam, diphenylhydantoin, flunitrazepam and haloperidol on the voltage-dependent sodium current of isolated mammalian brain neurons. Brain Res. 494 (1989) 374-378
-
(1989)
Brain Res.
, vol.494
, pp. 374-378
-
-
Wakamori, M.1
Kaneda, M.2
Oyama, Y.3
Akaike, N.4
-
141
-
-
0027200131
-
Glycine reversal of felbamate hypoxic protection
-
Wallis R.A., and Panizzon K.L. Glycine reversal of felbamate hypoxic protection. Neuroreport 4 (1993) 951-954
-
(1993)
Neuroreport
, vol.4
, pp. 951-954
-
-
Wallis, R.A.1
Panizzon, K.L.2
-
142
-
-
0029591971
-
Felbamate neuroprotection against CA1 traumatic neuronal injury
-
Wallis R.A., and Panizzon K.L. Felbamate neuroprotection against CA1 traumatic neuronal injury. Eur. J. Pharmacol. 294 (1995) 475-482
-
(1995)
Eur. J. Pharmacol.
, vol.294
, pp. 475-482
-
-
Wallis, R.A.1
Panizzon, K.L.2
-
143
-
-
0001812259
-
Oxcarbazepine and its monohydroxy metabolite limit action potential firing by mouse central neurons in cell culture [abstract]
-
Wamil A.W. Oxcarbazepine and its monohydroxy metabolite limit action potential firing by mouse central neurons in cell culture [abstract]. Epilepsia 32 Suppl. 3 (1991) 65
-
(1991)
Epilepsia
, vol.32
, Issue.SUPPL. 3
, pp. 65
-
-
Wamil, A.W.1
-
144
-
-
0027977004
-
Limitation by gabapentin of high frequency action potential firing by mouse central neurons in cell culture
-
Wamil A.W., and McLean M.J. Limitation by gabapentin of high frequency action potential firing by mouse central neurons in cell culture. Epilepsy Res. 17 (1994) 1-11
-
(1994)
Epilepsy Res.
, vol.17
, pp. 1-11
-
-
Wamil, A.W.1
McLean, M.J.2
-
145
-
-
0028171975
-
Interaction of felbamate with [3H]DCKA-labeled strychnine-insensitive glycine receptors in human postmortem brain
-
Wamsley J.K., Sofia R.D., Faull R.L., Narang N., Ary T., and McCabe R.T. Interaction of felbamate with [3H]DCKA-labeled strychnine-insensitive glycine receptors in human postmortem brain. Exp. Neurol. 129 (1994) 244-250
-
(1994)
Exp. Neurol.
, vol.129
, pp. 244-250
-
-
Wamsley, J.K.1
Sofia, R.D.2
Faull, R.L.3
Narang, N.4
Ary, T.5
McCabe, R.T.6
-
146
-
-
0027723017
-
Gabapentin anticonvulsant action in rats: Disequilibrium with peak drug concentrations in plasma and brain microdialysate
-
Welty D.F., Schielke G.P., Vartanian M.G., and Taylor C.P. Gabapentin anticonvulsant action in rats: Disequilibrium with peak drug concentrations in plasma and brain microdialysate. Epilepsy Res. 16 (1993) 175-181
-
(1993)
Epilepsy Res.
, vol.16
, pp. 175-181
-
-
Welty, D.F.1
Schielke, G.P.2
Vartanian, M.G.3
Taylor, C.P.4
-
147
-
-
0002017661
-
Mechanisms of antiepileptic drugs
-
Porter R., and Chadwick D. (Eds), Butterworth-Heinemann, Boston
-
White H.S. Mechanisms of antiepileptic drugs. In: Porter R., and Chadwick D. (Eds). "Epilepsies II" (1997), Butterworth-Heinemann, Boston 1-30
-
(1997)
"Epilepsies II"
, pp. 1-30
-
-
White, H.S.1
-
148
-
-
0032848061
-
Comparative anticonvulsant and mechanistic profile of the established and newer antiepileptic drugs
-
White H.S. Comparative anticonvulsant and mechanistic profile of the established and newer antiepileptic drugs. Epilepsia 40 Suppl. 5 (1999) S2-S10
-
(1999)
Epilepsia
, vol.40
, Issue.SUPPL. 5
-
-
White, H.S.1
-
149
-
-
0041451398
-
Topiramate: Mechanisms of action
-
Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds), Lippincott Williams & Wilkins, Philadelphia
-
White H.S. Topiramate: Mechanisms of action. In: Levy R.H., Mattson R.H., Meldrum B.S., and Perucca E. (Eds). "Antiepileptic Drugs". 5th ed. (2002), Lippincott Williams & Wilkins, Philadelphia 719-726
-
(2002)
"Antiepileptic Drugs". 5th ed.
, pp. 719-726
-
-
White, H.S.1
-
150
-
-
0026742204
-
A neuropharmacological evaluation of felbamate as a novel anticonvulsant
-
White H.S., Wolf H.H., Swinyard E.A., Skeen G.A., and Sofia R.D. A neuropharmacological evaluation of felbamate as a novel anticonvulsant. Epilepsia 33 (1992) 564-572
-
(1992)
Epilepsia
, vol.33
, pp. 564-572
-
-
White, H.S.1
Wolf, H.H.2
Swinyard, E.A.3
Skeen, G.A.4
Sofia, R.D.5
-
151
-
-
0002394897
-
The anticonvulsant topiramate displays a unique ability to potentiate GABA-evoked chloride currents
-
White H.S., Brown D., Skeen G.A., Wolf H.H., and Twyman R.E. The anticonvulsant topiramate displays a unique ability to potentiate GABA-evoked chloride currents. Epilepsia 36 Suppl. 3 (1995) S39-S40
-
(1995)
Epilepsia
, vol.36
, Issue.SUPPL. 3
-
-
White, H.S.1
Brown, D.2
Skeen, G.A.3
Wolf, H.H.4
Twyman, R.E.5
-
153
-
-
0002021428
-
General principles: Experimental selection, quantification, and evaluation of antiepileptic drugs
-
Levy R.H., Mattson R.H., and Meldrum B.S. (Eds), Raven Press, New York
-
White H.S., Woodhead J.H., Franklin M.R., Swinyard E.A., and Wolf H.H. General principles: Experimental selection, quantification, and evaluation of antiepileptic drugs. In: Levy R.H., Mattson R.H., and Meldrum B.S. (Eds). "Antiepileptic Drugs". 4th ed. (1995), Raven Press, New York 99-110
-
(1995)
"Antiepileptic Drugs". 4th ed.
, pp. 99-110
-
-
White, H.S.1
Woodhead, J.H.2
Franklin, M.R.3
Swinyard, E.A.4
Wolf, H.H.5
-
154
-
-
0030758984
-
Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold
-
White H.S., Brown S.D., Woodhead J.H., Skeen G.A., and Wolf H.H. Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold. Epilepsy Res. 28 (1997) 167-179
-
(1997)
Epilepsy Res.
, vol.28
, pp. 167-179
-
-
White, H.S.1
Brown, S.D.2
Woodhead, J.H.3
Skeen, G.A.4
Wolf, H.H.5
-
155
-
-
0020334077
-
Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine
-
Willow M., and Catterall W.A. Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol. Pharmacol. 22 (1982) 627-635
-
(1982)
Mol. Pharmacol.
, vol.22
, pp. 627-635
-
-
Willow, M.1
Catterall, W.A.2
-
156
-
-
0021347623
-
Inhibition of voltage-sensitive sodium channels in neuroblastoma cells and synaptosomes by the anticonvulsant drugs diphenylhydantoin and carbamazepine
-
Willow M., Kuenzel E.A., and Catterall W.A. Inhibition of voltage-sensitive sodium channels in neuroblastoma cells and synaptosomes by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol. Pharmacol. 25 (1984) 228-234
-
(1984)
Mol. Pharmacol.
, vol.25
, pp. 228-234
-
-
Willow, M.1
Kuenzel, E.A.2
Catterall, W.A.3
-
157
-
-
0021913947
-
Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells
-
Willow M., Gonoi T., and Catterall W.A. Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells. Mol. Pharmacol. 27 (1985) 549-558
-
(1985)
Mol. Pharmacol.
, vol.27
, pp. 549-558
-
-
Willow, M.1
Gonoi, T.2
Catterall, W.A.3
-
158
-
-
0028858375
-
The sensitivity of AMPA-selective glutamate receptor channels to pentobarbital is determined by a single amino acid residue of the alpha 2 subunit
-
Yamakura T., Sakimura K., Mishina M., and Shimoji K. The sensitivity of AMPA-selective glutamate receptor channels to pentobarbital is determined by a single amino acid residue of the alpha 2 subunit. FEBS Lett. 374 (1995) 412-414
-
(1995)
FEBS Lett.
, vol.374
, pp. 412-414
-
-
Yamakura, T.1
Sakimura, K.2
Mishina, M.3
Shimoji, K.4
-
159
-
-
0345583240
-
Topiramate reduces high-voltage activated Ca2+ currents in CA1 pyramidal neurons in vitro [abstract]
-
Zhang X., Velumian A.A., Jones O.T., and Carlen P.L. Topiramate reduces high-voltage activated Ca2+ currents in CA1 pyramidal neurons in vitro [abstract]. Epilepsia 39 Suppl. 6 (1998) 44
-
(1998)
Epilepsia
, vol.39
, Issue.SUPPL. 6
, pp. 44
-
-
Zhang, X.1
Velumian, A.A.2
Jones, O.T.3
Carlen, P.L.4
-
160
-
-
0034076789
-
Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate
-
Zhang X., Velumian A.A., Jones O.T., and Carlen P.L. Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate. Epilepsia 41 Suppl. 1 (2000) S52-S60
-
(2000)
Epilepsia
, vol.41
, Issue.SUPPL. 1
-
-
Zhang, X.1
Velumian, A.A.2
Jones, O.T.3
Carlen, P.L.4
-
161
-
-
0025348895
-
Effects induced by the antiepileptic drug valproic acid upon the ionic currents recorded in rat neocortical neurons in cell culture
-
Zona C., and Avoli M. Effects induced by the antiepileptic drug valproic acid upon the ionic currents recorded in rat neocortical neurons in cell culture. Exp. Brain Res. 81 (1990) 313-317
-
(1990)
Exp. Brain Res.
, vol.81
, pp. 313-317
-
-
Zona, C.1
Avoli, M.2
-
162
-
-
0030867764
-
Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells
-
Zona C., Ciotti M.T., and Avoli M. Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells. Neurosci. Lett. 231 (1997) 123-126
-
(1997)
Neurosci. Lett.
, vol.231
, pp. 123-126
-
-
Zona, C.1
Ciotti, M.T.2
Avoli, M.3
|