An overview of the preclinical aspects of topiramate: Pharmacology, pharmacokinetics, and mechanism of action

Epilepsia

Volumn 41, Issue 4 SUPPL., 2000, Pages

  Wieser, Heinz Gregor ^a   Silfvenius, Herbert ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UMEÅ UNIVERSITY HOSPITAL   (Sweden)

Author keywords

AMPA kainate receptors; Anticonvulsant; Epilepsy; GABA(A) receptors; Na+ channels; Topiramate

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ACETAZOLAMIDE; CALCIUM CHANNEL; CALCIUM ION; CARBAMAZEPINE; CARBONATE DEHYDRATASE; CHLORIDE ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUTAMATE RECEPTOR; KAINIC ACID; MEMBRANE PROTEIN; PHENOBARBITAL; PHENYTOIN; PLASMA PROTEIN; POTASSIUM ION; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE C; SODIUM CHANNEL; SODIUM ION; TOPIRAMATE; VALPROIC ACID;

ANTICONVULSANT ACTIVITY; ARTICLE; CHLORIDE CURRENT; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME INHIBITION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEIZURE; CONFERENCE PAPER; DEVELOPING COUNTRY; ELECTROENCEPHALOGRAM; EPILEPSY; HEALTH CARE COST; INTERNATIONAL COOPERATION; NEUROPSYCHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING;

ADOLESCENT; ADULT; DEVELOPED COUNTRIES; DEVELOPING COUNTRIES; EPILEPSY; FEMALE; HEALTH CARE COSTS; HEALTH CARE SURVEYS; HUMANS; INTERNATIONAL COOPERATION; MALE; OUTCOME ASSESSMENT (HEALTH CARE); VITAL STATISTICS; WORLD HEALTH ORGANIZATION;

EID: 0034034180     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1157.2000.tb01538.x     Document Type: Article

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