Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold

Epilepsy Research

Volumn 28, Issue 3, 1997, Pages 167-179

  White, H Steve ^a   Brown, S Douglas ^a   Woodhead, Jose H ^a   Skeen, Gwendolyn A ^a   Wolf, Harold H ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Chloride channel; GABA(A) receptor; N (ethoxycarbonylmethyl) 6 methoxyquinolinium bromide

Indexed keywords

4 AMINOBUTYRIC ACID; ACETAZOLAMIDE; BICUCULLINE; CLONAZEPAM; PENTETRAZOLE; PHENYTOIN; PICROTOXIN; TOPIRAMATE;

ANIMAL CELL; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN CORTEX; CHLORIDE CURRENT; CHLORIDE TRANSPORT; DRUG EFFECT; DRUG MECHANISM; ELECTROPHYSIOLOGY; EVOKED RESPONSE; GRANULE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEIZURE THRESHOLD; SPIKE WAVE;

ANIMALS; ANTICONVULSANTS; BRAIN; CELLS, CULTURED; CHLORIDE CHANNELS; CONVULSANTS; DRUG SYNERGISM; FLUORESCENT DYES; FRUCTOSE; GAMMA-AMINOBUTYRIC ACID; INFUSIONS, INTRAVENOUS; MICE; NEURONS; PATCH-CLAMP TECHNIQUES; PENTYLENETETRAZOLE; SEIZURES;

EID: 0030758984     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(97)00045-4     Document Type: Article

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