-
1
-
-
0033635292
-
Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system
-
Alcedo, J., Zou, Y. and Noll, M. (2000). Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system. Mol. Cell 6, 457-465.
-
(2000)
Mol. Cell
, vol.6
, pp. 457-465
-
-
Alcedo, J.1
Zou, Y.2
Noll, M.3
-
2
-
-
0031587830
-
Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor
-
Aza-Blanc, P., Ramirez-Weber, F. A., Laget, M. P., Schwartz, C. and Kornberg, T. B. (1997). Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor. Cell 89, 1043-1053.
-
(1997)
Cell
, vol.89
, pp. 1043-1053
-
-
Aza-Blanc, P.1
Ramirez-Weber, F.A.2
Laget, M.P.3
Schwartz, C.4
Kornberg, T.B.5
-
3
-
-
0030460814
-
Segmentation and specification of the Drosophila mesoderm
-
Azpiazu, N., Lawrence, P. A., Vincent, J. P. and Frasch, M. (1996). Segmentation and specification of the Drosophila mesoderm. Genes Dev. 10, 3183-3194.
-
(1996)
Genes Dev.
, vol.10
, pp. 3183-3194
-
-
Azpiazu, N.1
Lawrence, P.A.2
Vincent, J.P.3
Frasch, M.4
-
4
-
-
0023667001
-
Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene
-
Boggs, R. T., Gregor, P., Idriss, S., Belote, J. M. and McKeown, M. (1987). Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene. Cell 50, 739-747.
-
(1987)
Cell
, vol.50
, pp. 739-747
-
-
Boggs, R.T.1
Gregor, P.2
Idriss, S.3
Belote, J.M.4
McKeown, M.5
-
5
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
6
-
-
4544331178
-
Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein
-
Casali, A. and Struhl, G. (2004). Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein. Nature 431, 76-80.
-
(2004)
Nature
, vol.431
, pp. 76-80
-
-
Casali, A.1
Struhl, G.2
-
7
-
-
0033529667
-
Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression
-
Chen, C. H., von Kessler, D. P., Park, W., Wang, B., Ma, Y. and Beachy, P. A. (1999). Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression. Cell 98, 305-316.
-
(1999)
Cell
, vol.98
, pp. 305-316
-
-
Chen, C.H.1
von Kessler, D.P.2
Park, W.3
Wang, B.4
Ma, Y.5
Beachy, P.A.6
-
8
-
-
0021287395
-
Autoregulatory functioning of a Drosophila gene product that establishes and maintains the sexually determined state
-
Cline, T. (1984). Autoregulatory functioning of a Drosophila gene product that establishes and maintains the sexually determined state. Genetics 107, 231-277.
-
(1984)
Genetics
, vol.107
, pp. 231-277
-
-
Cline, T.1
-
9
-
-
0034682719
-
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
-
Denef, N., Neubuser, D., Perez, L. and Cohen, S. M. (2000). Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened. Cell 102, 521-531.
-
(2000)
Cell
, vol.102
, pp. 521-531
-
-
Denef, N.1
Neubuser, D.2
Perez, L.3
Cohen, S.M.4
-
10
-
-
0029896212
-
Sending and receiving the hedgehog signal: Control by the Drosophila Gli protein Cubitus interruptus
-
Dominguez, M., Brunner, M., Hafen, E. and Basler, K. (1996). Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science 272, 1621-1625.
-
(1996)
Science
, vol.272
, pp. 1621-1625
-
-
Dominguez, M.1
Brunner, M.2
Hafen, E.3
Basler, K.4
-
11
-
-
0033639077
-
Gradient formation of the TGF-beta homolog Dpp
-
Entchev, E. V., Schwabedissen, A. and González-Gaitán, M. (2000). Gradient formation of the TGF-beta homolog Dpp. Cell 103, 981-991.
-
(2000)
Cell
, vol.103
, pp. 981-991
-
-
Entchev, E.V.1
Schwabedissen, A.2
González-Gaitán, M.3
-
12
-
-
0024293520
-
Association of the Drosophila melanogaster engrailed protein with specific soluble nuclear protein complexes
-
Gay, N. J., Poole, S. and Kornberg, T. (1988). Association of the Drosophila melanogaster engrailed protein with specific soluble nuclear protein complexes. EMBO J. 7, 4291-4297.
-
(1988)
EMBO J.
, vol.7
, pp. 4291-4297
-
-
Gay, N.J.1
Poole, S.2
Kornberg, T.3
-
13
-
-
1242329977
-
Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process
-
Han, C., Belenkaya, T. Y., Wang, B. and Lin, X. (2004). Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process. Development 131, 601-611.
-
(2004)
Development
, vol.131
, pp. 601-611
-
-
Han, C.1
Belenkaya, T.Y.2
Wang, B.3
Lin, X.4
-
14
-
-
0041827271
-
Smoothened translates Hedgehog levels into distinct responses
-
Hooper, J. E. (2003). Smoothened translates Hedgehog levels into distinct responses. Development 130, 3951-3963.
-
(2003)
Development
, vol.130
, pp. 3951-3963
-
-
Hooper, J.E.1
-
15
-
-
28044463370
-
Splitting the Hedgehog signal: Sex and patterning in Drosophila
-
Horabin, J. I. (2005). Splitting the Hedgehog signal: sex and patterning in Drosophila. Development 132, 4801-4810.
-
(2005)
Development
, vol.132
, pp. 4801-4810
-
-
Horabin, J.I.1
-
16
-
-
0347519181
-
A positive role for Patched in Hedgehog signaling revealed by the intracellular trafficking of Sex-lethal, the Drosophila sex determination master switch
-
Horabin, J. I., Walthall, S., Vied, C. and Moses, M. (2003). A positive role for Patched in Hedgehog signaling revealed by the intracellular trafficking of Sex-lethal, the Drosophila sex determination master switch. Development 130, 6101-6109.
-
(2003)
Development
, vol.130
, pp. 6101-6109
-
-
Horabin, J.I.1
Walthall, S.2
Vied, C.3
Moses, M.4
-
17
-
-
0037172658
-
Sonic hedgehog induces the segregation of patched and smoothened in endosomes
-
Incardona, J. P., Gruenberg, J. and Roelink, H. (2002). Sonic hedgehog induces the segregation of patched and smoothened in endosomes. Curr. Biol. 12, 983-989.
-
(2002)
Curr. Biol.
, vol.12
, pp. 983-989
-
-
Incardona, J.P.1
Gruenberg, J.2
Roelink, H.3
-
18
-
-
0242361620
-
Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail
-
Jia, J., Tong, C. and Jiang, J. (2003). Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail. Genes Dev. 17, 2709-2720.
-
(2003)
Genes Dev.
, vol.17
, pp. 2709-2720
-
-
Jia, J.1
Tong, C.2
Jiang, J.3
-
19
-
-
11144237279
-
Hedgehog signaling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I
-
Jia, J., Tong, C., Wang, B., Luo, L. and Jiang, J. (2004). Hedgehog signaling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I. Nature 432, 1045-1050.
-
(2004)
Nature
, vol.432
, pp. 1045-1050
-
-
Jia, J.1
Tong, C.2
Wang, B.3
Luo, L.4
Jiang, J.5
-
20
-
-
0032576777
-
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/ WD40-repeat protein Slimb
-
Jiang, J. and Struhl, G. (1998). Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature 391, 493-496.
-
(1998)
Nature
, vol.391
, pp. 493-496
-
-
Jiang, J.1
Struhl, G.2
-
21
-
-
0033636788
-
In vivo functions of the patched protein: Requirement of the C terminus for target gene inactivation but not Hedgehog sequestration
-
Johnson, R. L., Milenkovic, L. and Scott, M. P. (2000). In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration. Mol. Cell 6, 467-478.
-
(2000)
Mol. Cell
, vol.6
, pp. 467-478
-
-
Johnson, R.L.1
Milenkovic, L.2
Scott, M.P.3
-
22
-
-
0037083492
-
Distinct consequences of sterol sensor mutations in Drosophila and mouse patched homologs
-
Johnson, R. L., Zhou, L. and Bailey, E. C. (2002). Distinct consequences of sterol sensor mutations in Drosophila and mouse patched homologs. Dev. Biol. 242, 224-235.
-
(2002)
Dev. Biol.
, vol.242
, pp. 224-235
-
-
Johnson, R.L.1
Zhou, L.2
Bailey, E.C.3
-
23
-
-
0037086443
-
Late endosome motility depends on lipids via the small GTPase Rab7
-
Lebrand, C., Corti, M., Goodson, H., Cosson, P., Cavalli, V., Mayran, N., Faure, J. and Gruenberg, J. (2002). Late endosome motility depends on lipids via the small GTPase Rab7. EMBO J. 21, 1289-1300.
-
(2002)
EMBO J.
, vol.21
, pp. 1289-1300
-
-
Lebrand, C.1
Corti, M.2
Goodson, H.3
Cosson, P.4
Cavalli, V.5
Mayran, N.6
Faure, J.7
Gruenberg, J.8
-
24
-
-
0031866079
-
Expression of wingless in the Drosophila embryo: A conserved cis-acting element lacking conserved Ci-binding sites is required for patched-mediated repression
-
Lessing, D. and Nusse, R. (1998). Expression of wingless in the Drosophila embryo: a conserved cis-acting element lacking conserved Ci-binding sites is required for patched-mediated repression. Development 125, 1469-1476.
-
(1998)
Development
, vol.125
, pp. 1469-1476
-
-
Lessing, D.1
Nusse, R.2
-
25
-
-
33748690784
-
The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover
-
Lu, X., Liu, S. and Kornberg, T. B. (2006). The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover. Genes Dev. 20, 2539-2551.
-
(2006)
Genes Dev.
, vol.20
, pp. 2539-2551
-
-
Lu, X.1
Liu, S.2
Kornberg, T.B.3
-
26
-
-
29444458753
-
Chromatin remodeling in dosage compensation
-
Lucchesi, J. C., Kelly, W. G. and Panning, B. (2005). Chromatin remodeling in dosage compensation. Annu. Rev. Genet. 39, 615-651.
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 615-651
-
-
Lucchesi, J.C.1
Kelly, W.G.2
Panning, B.3
-
27
-
-
10744233219
-
Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2
-
Lum, L., Zhang, C., Oh, S., Mann, R. K., von Kessler, D. P., Taipale, J., Weis-Garcia, F., Gong, R., Wang, B. and Beachy, P. A. (2003). Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2. Mol. Cell 12, 1261-1274.
-
(2003)
Mol. Cell
, vol.12
, pp. 1261-1274
-
-
Lum, L.1
Zhang, C.2
Oh, S.3
Mann, R.K.4
von Kessler, D.P.5
Taipale, J.6
Weis-Garcia, F.7
Gong, R.8
Wang, B.9
Beachy, P.A.10
-
28
-
-
0035901616
-
The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking
-
Martin, V., Carrillo, G., Torroja, C. and Guerrero, I. (2001). The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking. Curr. Biol. 11, 601-607.
-
(2001)
Curr Biol.
, vol.11
, pp. 601-607
-
-
Martin, V.1
Carrillo, G.2
Torroja, C.3
Guerrero, I.4
-
29
-
-
0023652360
-
A molecular analysis of transformer, a gene in Drosophila melanogaster that controls sexual differentiation
-
McKeown, M., Belote, J. M. and Baker, B. S. (1987). A molecular analysis of transformer, a gene in Drosophila melanogaster that controls sexual differentiation. Cell 48, 489-499.
-
(1987)
Cell
, vol.48
, pp. 489-499
-
-
McKeown, M.1
Belote, J.M.2
Baker, B.S.3
-
30
-
-
0033582908
-
Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus
-
Methot, N. and Basler, K. (1999). Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. Cell 96, 819-831.
-
(1999)
Cell
, vol.96
, pp. 819-831
-
-
Methot, N.1
Basler, K.2
-
31
-
-
0033789068
-
Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus/
-
Methot, N. and Basler, K. (2000). Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. Development 127, 4001-4010.
-
(2000)
Development
, vol.127
, pp. 4001-4010
-
-
Methot, N.1
Basler, K.2
-
32
-
-
0032759039
-
Directionality of Wingless protein transport influences epidermal patterning in the Drosophila embryo
-
Moline, M. M., Southern, C. and Bejsovec, A. (1999). Directionality of Wingless protein transport influences epidermal patterning in the Drosophila embryo. Development 126, 4375-4384.
-
(1999)
Development
, vol.126
, pp. 4375-4384
-
-
Moline, M.M.1
Southern, C.2
Bejsovec, A.3
-
33
-
-
0009603803
-
Sonic hedgehog signaling by the patched-smoothened receptor complex
-
Murone, M., Rosenthal, A. and de Sauvage, F. J. (1999). Sonic hedgehog signaling by the patched-smoothened receptor complex. Curr. Biol. 9, 76-84.
-
(1999)
Curr. Biol.
, vol.9
, pp. 76-84
-
-
Murone, M.1
Rosenthal, A.2
de Sauvage, F.J.3
-
34
-
-
0037025382
-
Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused
-
Nybakken, K. E., Turck, C. W., Robbins, D. J. and Bishop, J. M. (2002). Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused. J. Biol. Chem. 277, 24638-24647.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24638-24647
-
-
Nybakken, K.E.1
Turck, C.W.2
Robbins, D.J.3
Bishop, J.M.4
-
35
-
-
0242625184
-
Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2
-
Ogden, S. K., Ascano, M., Jr, Stegman, M. A., Suber, L. M., Hooper, J. E. and Robbins, D. J. (2003). Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2. Curr. Biol. 13, 1998-2003.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1998-2003
-
-
Ogden, S.K.1
Ascano Jr., M.2
Stegman, M.A.3
Suber, L.M.4
Hooper, J.E.5
Robbins, D.J.6
-
36
-
-
0032585515
-
Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator
-
Ohlmeyer, J. T. and Kalderon, D. (1998). Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator. Nature 396, 749-753.
-
(1998)
Nature
, vol.396
, pp. 749-753
-
-
Ohlmeyer, J.T.1
Kalderon, D.2
-
37
-
-
0036333130
-
Inductive patterning of the embryonic brain in Drosophila
-
Page, D. T. (2002). Inductive patterning of the embryonic brain in Drosophila. Development 129, 2121-2128.
-
(2002)
Development
, vol.129
, pp. 2121-2128
-
-
Page, D.T.1
-
38
-
-
0042767664
-
Modulation of developmental signals by endocytosis: Different means and many ends
-
Piddini, E. and Vincent, J. P. (2003). Modulation of developmental signals by endocytosis: different means and many ends. Curr. Opin. Cell Biol. 15, 474-481.
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 474-481
-
-
Piddini, E.1
Vincent, J.P.2
-
39
-
-
24144442691
-
Rab conversion as a mechanism of progression from early to late endosomes
-
Rink, J., Ghigo, E., Kalaidzidis, Y. and Zerial, M. (2005). Rab conversion as a mechanism of progression from early to late endosomes. Cell 122, 735-749.
-
(2005)
Cell
, vol.122
, pp. 735-749
-
-
Rink, J.1
Ghigo, E.2
Kalaidzidis, Y.3
Zerial, M.4
-
40
-
-
0030838880
-
Hedgehog elicits signal transduction by means of a large complex containing the kinesin related protein costal2
-
Robbins, D. J., Nybakken, K. E., Kobayashi, R., Sisson, J. C., Bishop, J. M. and Therond, P. P. (1997). Hedgehog elicits signal transduction by means of a large complex containing the kinesin related protein costal2. Cell 90, 225-234.
-
(1997)
Cell
, vol.90
, pp. 225-234
-
-
Robbins, D.J.1
Nybakken, K.E.2
Kobayashi, R.3
Sisson, J.C.4
Bishop, J.M.5
Therond, P.P.6
-
41
-
-
0141728540
-
Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog
-
Ruel, L., Rodriguez, R., Gullet, A., Lavenant-Staccini, L. and Therond, P. P. (2003). Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog. Nat. Cell Biol. 5, 907-913.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 907-913
-
-
Ruel, L.1
Rodriguez, R.2
Gullet, A.3
Lavenant-Staccini, L.4
Therond, P.P.5
-
42
-
-
0000410458
-
Sex determination and dosage compensation in Drosophila melanogaster: Production of male clones in XX females
-
Sanchez, L. and Nöthiger, R. (1983). Sex determination and dosage compensation in Drosophila melanogaster: production of male clones in XX females. EMBO J. 2, 211-214.
-
(1983)
EMBO J.
, vol.2
, pp. 211-214
-
-
Sanchez, L.1
Nöthiger, R.2
-
43
-
-
0030754171
-
Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway
-
Sisson, J. C., Ho, K. S., Snyama, K. and Scott, M. P. (1997). Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway. Cell 90, 235-245.
-
(1997)
Cell
, vol.90
, pp. 235-245
-
-
Sisson, J.C.1
Ho, K.S.2
Snyama, K.3
Scott, M.P.4
-
44
-
-
0034698137
-
Identification of a tetrameric hedgehog signaling complex
-
Stegman, M. A., Vallance, J. E., Elangovan, G., Sosinski, J., Cheng, Y. and Robbins, D. J. (2000). Identification of a tetrameric hedgehog signaling complex. J. Biol. Chem. 275, 21809-21812.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 21809-21812
-
-
Stegman, M.A.1
Vallance, J.E.2
Elangovan, G.3
Sosinski, J.4
Cheng, Y.5
Robbins, D.J.6
-
45
-
-
1342282946
-
The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner
-
Stegman, M. A., Goetz, J. A., Ascano, M., Jr, Ogden, S. K., Nybakken, K. E. and Robbins, D. J. (2004). The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner. J. Biol. Chem. 279, 7064-7071.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7064-7071
-
-
Stegman, M.A.1
Goetz, J.A.2
Ascano Jr., M.3
Ogden, S.K.4
Nybakken, K.E.5
Robbins, D.J.6
-
46
-
-
0028261425
-
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
-
Stenmark, H., Parton, R. G., Steele-Mortimer, O., Lueteke, A., Gruenberg, J. and Zerial, M. (1994). Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. EMBO J. 13, 1287-1296.
-
(1994)
EMBO J.
, vol.13
, pp. 1287-1296
-
-
Stenmark, H.1
Parton, R.G.2
Steele-Mortimer, O.3
Lueteke, A.4
Gruenberg, J.5
Zerial, M.6
-
47
-
-
0011102935
-
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
-
Stone, D. M., Hynes, M., Armanini, M., Swanson, T. A., Gu, Q., Johnson, R. L., Scott, M. P., Pennica, D., Goddard, A., Phillips, H. et al. (1996). The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384, 129-134.
-
(1996)
Nature
, vol.384
, pp. 129-134
-
-
Stone, D.M.1
Hynes, M.2
Armanini, M.3
Swanson, T.A.4
Gu, Q.5
Johnson, R.L.6
Scott, M.P.7
Pennica, D.8
Goddard, A.9
Phillips, H.10
-
48
-
-
0035901572
-
Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation [erratum appears in Curr. Biol. (2001). 11, 1153]
-
Strutt, H., Thomas, C., Nakano, Y., Stark, D., Neave, B., Taylor, A. M. and Ingham, P. W. (2001). Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation. [erratum appears in Curr. Biol. (2001). 11, 1153] Curr. Biol. 11, 608-613.
-
(2001)
Curr. Biol.
, vol.11
, pp. 608-613
-
-
Strutt, H.1
Thomas, C.2
Nakano, Y.3
Stark, D.4
Neave, B.5
Taylor, A.M.6
Ingham, P.W.7
-
49
-
-
0037158748
-
Patched acts catalytically to suppress the activity of Smoothened
-
Taipale, J., Cooper, M. K., Maiti, T. and Beachy, P. A. (2002). Patched acts catalytically to suppress the activity of Smoothened. Nature 418, 892-897.
-
(2002)
Nature
, vol.418
, pp. 892-897
-
-
Taipale, J.1
Cooper, M.K.2
Maiti, T.3
Beachy, P.A.4
-
50
-
-
0029961659
-
Phosphorylation of the fused protein kinase in response to signaling from hedgehog
-
Therond, P. P., Knight, J. D., Kornberg, T. B. and Bishop, J. M. (1996). Phosphorylation of the fused protein kinase in response to signaling from hedgehog. Proc. Natl. Acad. Sci. USA 93, 4224-4228.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4224-4228
-
-
Therond, P.P.1
Knight, J.D.2
Kornberg, T.B.3
Bishop, J.M.4
-
51
-
-
3042799334
-
Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction
-
Torroja, C., Gorfinkiel, N. and Guerrero, I. (2004). Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction. Development 131, 2395-2408.
-
(2004)
Development
, vol.131
, pp. 2395-2408
-
-
Torroja, C.1
Gorfinkiel, N.2
Guerrero, I.3
-
52
-
-
23444443064
-
Mechanisms of Hedgehog gradient formation and interpretation
-
Torroja, C., Gorfinkiel, N. and Guerrero, I. (2005). Mechanisms of Hedgehog gradient formation and interpretation. J. Neurobiol. 64, 334-356.
-
(2005)
J. Neurobiol.
, vol.64
, pp. 334-356
-
-
Torroja, C.1
Gorfinkiel, N.2
Guerrero, I.3
-
53
-
-
0025810110
-
Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic
-
van der Bliek, A. M. and Meyerowitz, E. M. (1991). Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic. Nature 351, 411-414.
-
(1991)
Nature
, vol.351
, pp. 411-414
-
-
van der Bliek, A.M.1
Meyerowitz, E.M.2
-
54
-
-
0034923839
-
The sex determination master switch, Sex-lethal, responds to Hedgehog signaling in the Drosophila germline
-
Vied, C. and Horabin, J. I. (2001). The sex determination master switch, Sex-lethal, responds to Hedgehog signaling in the Drosophila germline. Development 128, 2649-2660.
-
(2001)
Development
, vol.128
, pp. 2649-2660
-
-
Vied, C.1
Horabin, J.I.2
-
55
-
-
0031058474
-
Role of the small GTPase Rab7 in the late endocytic pathway
-
Vitelli, R., Santillo, M., Lattero, D., Chiariello, M., Bifulco, M., Bruni, C. B. and Bucci, C. (1997). Role of the small GTPase Rab7 in the late endocytic pathway. J. Biol. Chem. 272, 4391-4397.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4391-4397
-
-
Vitelli, R.1
Santillo, M.2
Lattero, D.3
Chiariello, M.4
Bifulco, M.5
Bruni, C.B.6
Bucci, C.7
-
56
-
-
0033404607
-
The subcellular localization and activity of Drosophila cubitus interruptus are regulated at multiple levels
-
Wang, Q. T. and Holmgren, R. A. (1999). The subcellular localization and activity of Drosophila cubitus interruptus are regulated at multiple levels. Development 126, 5097-5106.
-
(1999)
Development
, vol.126
, pp. 5097-5106
-
-
Wang, Q.T.1
Holmgren, R.A.2
-
57
-
-
0029045343
-
Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila
-
Wodarz, A., Hinz, U., Engelbert, M. and Knust, E. (1995). Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila. Cell 82, 67-76.
-
(1995)
Cell
, vol.82
, pp. 67-76
-
-
Wodarz, A.1
Hinz, U.2
Engelbert, M.3
Knust, E.4
-
58
-
-
33646035770
-
The ihog cell-surface proteins bind Hedgehog and mediate pathway activation
-
Yao, S., Lum, L. and Beachy, P. A. (2006). The ihog cell-surface proteins bind Hedgehog and mediate pathway activation. Cell 125, 343-357.
-
(2006)
Cell
, vol.125
, pp. 343-357
-
-
Yao, S.1
Lum, L.2
Beachy, P.A.3
-
59
-
-
11144248964
-
Extensive phosphorylation of Smoothened in Hedgehog pathway activation
-
Zhang, C., Williams, E. H., Guo, Y., Lum, L. and Beachy, P. A. (2004). Extensive phosphorylation of Smoothened in Hedgehog pathway activation. Proc. Natl. Acad. Sci. USA 101, 17900-17907.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17900-17907
-
-
Zhang, C.1
Williams, E.H.2
Guo, Y.3
Lum, L.4
Beachy, P.A.5
-
60
-
-
0038625111
-
Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction
-
Zhu, A. J., Zheng, L., Suyama, K. and Scott, M. P. (2003). Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction. Genes Dev. 17, 1240-1252.
-
(2003)
Genes Dev.
, vol.17
, pp. 1240-1252
-
-
Zhu, A.J.1
Zheng, L.2
Suyama, K.3
Scott, M.P.4
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