New highly hydrosoluble and not self-aggregated perylene derivatives with three and four polar side-chains as G-quadruplex telomere targeting agents and telomerase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 9, 2007, Pages 2515-2522

  Franceschin, Marco ^a   Pascucci, Emanuela ^a   Alvino, Antonello ^a   D'Ambrosio, Danilo ^a   Bianco, Armandodoriano ^a   Ortaggi, Giancarlo ^a   Savino, Maria ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

G quadruplex; Hydrosoluble perylene derivatives; Telomerase inhibitors

Indexed keywords

PERYLENE DERIVATIVE; TELOMERASE; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG SOLUBILITY; DRUG STRUCTURE; MOLECULAR MODEL; TELOMERE;

CHEMISTRY, PHARMACEUTICAL; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; MODELS, CHEMICAL; MOLECULAR CONFORMATION; NUCLEIC ACID CONFORMATION; PERYLENE; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; TELOMERASE; TELOMERE;

EID: 33947713244     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.02.021     Document Type: Article

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