Tri-, tetra- and heptacyclic perylene analogues as new potential antineoplastic agents based on DNA telomerase inhibition

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 1, 2007, Pages 555-562

  Sissi, Claudia ^a   Lucatello, Lorena ^a   Paul Krapcho, A ^b   Maloney, David J ^b   Boxer, Matthew B ^b   Camarasa, Maria V ^c   Pezzoni, Gabriella ^c   Menta, Ernesto ^c   Palumbo, Manlio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF VERMONT   (United States)

^c Cell Therapeutics Europe Srl   (Italy)

Author keywords

G quadruplex; Perylene; PIPER; Telomerase

Indexed keywords

PERYLENE; TAQ POLYMERASE; TELOMERASE; TELOMERASE INHIBITOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CIRCULAR DICHROISM; CYTOTOXICITY; DNA SYNTHESIS INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; MELTING POINT; POLYMERIZATION; PROTON TRANSPORT; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CIRCULAR DICHROISM; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; MOLECULAR STRUCTURE; PERYLENE; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TAQ POLYMERASE; TELOMERASE;

TETRA;

EID: 33750952242     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.09.029     Document Type: Article

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