The aggregation and G-quadruplex DNA selectivity of charged 3,4,9,10-perylenetetracarboxylic acid diimides

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 23, 2002, Pages 3395-3398

  Kern, Jonathan T ^a   Kerwin, Sean M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; DIMER; DOUBLE STRANDED DNA; MONOMER; N,N' BIS[(3 PHOSPHONO)PROPYL] 3,4,9,10 PERYLENE TETRACARBOXYLIC ACID DIIMIDE TETRAPOTASSIUM; N,N' BIS[3 (4 METHYLMORPHOLIN 4 YL)PROPYL] 3,4,8,9,10 PERYLENETETRACARBOXYLIC ACID DIIMIDE DIIODIDE; UNCLASSIFIED DRUG; DNA; DRUG DERIVATIVE; GUANINE; IMIDE; PERYLENE; QUADRUPLEX DNA;

ABSORPTION SPECTROSCOPY; ARTICLE; DNA STRUCTURE; DRUG SELECTIVITY; DRUG SYNTHESIS; FLUORESCENCE SPECTROSCOPY; LIGAND BINDING; LIGHT SCATTERING; CHEMISTRY; CONFORMATION; DNA BASE COMPOSITION; ENZYME SPECIFICITY; NUCLEOTIDE SEQUENCE; RADIATION SCATTERING; SPECTROFLUOROMETRY; ULTRAVIOLET SPECTROPHOTOMETRY;

BASE COMPOSITION; BASE SEQUENCE; DNA; GUANINE; IMIDES; NUCLEIC ACID CONFORMATION; PERYLENE; SCATTERING, RADIATION; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBSTRATE SPECIFICITY;

EID: 0036888355     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00763-1     Document Type: Article

References (21)

1. Kerwin S.M. Curr. Pharm. Des. 6:2000;441.
2. Shi D.-F., Wheelhouse R.T., Sun D., Hurley L.H. J. Med. Chem. 44:2001;4509.
3. Duan W., Rangan A., Vankayalapati H., Zeng Q., Sun D., Han H., Federoff O.Y., Nishioka D., Rha S.Y., Izbicka E., Von Hoff D.D., Hurley L.H. Mol. Canc. Ther. 1:2001;103.
4. Kerwin S.M., Sun D., Kern J.T., Rangan A., Thomas P.W. Bioorg. Med. Chem. Lett. 11:2001;2411.
5. Alberti P., Schmitt P., Nguyen C.-H., Rivalle C., Hoarau M., Grierson D.S., Mergny J.-L. Bioorg. Med. Chem. Lett. 12:2002;1071.
6. Federoff O.Y., Salazar M., Han H., Chemeris V.V., Kerwin S.M., Hurley L.H. Biochemistry. 37:1998;12367.
7. Han H., Cliff C.L., Hurley L.H. Biochemistry. 38:1999;6981.
8. Rangan A., Federoff O.Y., Hurley L.H. J. Biol. Chem. 276:2001;4640.
9. Han H., Bennett R.J., Hurley L.H. Biochemistry. 39:2000;9311.
10. Kerwin S.M., Chen G., Kern J.T., Thomas P.W. Bioorg. Med. Chem. Lett. 12:2002;447.
11. Kern, J. T.; Thomas, P. W.; Kerwin, S. M. Biochemistry 2002, 41, 11379.
12. Deligeorgiev T., Zaneva D., Petkov I., Timcheva Il., Sabnis R. Dyes Pigments. 24:1994;75.
13. 2O: C 49.80, H 4.81, N 5.81; found C 49.52, H 4.46, N 5.62.
14. 2O: C 42.85, H 3.12, N 3.33; found C 42.99, H 3.48, N 3.36.
15. Pasternack R.F., Collings P.J. Science. 269:1995;935.
16. Ford W.E. J. Photochem. 37:1987;189.
17. Langhals H., Ismael R., Yuruk O. Tetrahedon. 56:2000;5435.
18. Bevers S., Schutte S., McLaughlin J.W. J. Am. Chem. Soc. 122:2000;5905.
19. Garoff R.A., Litzinger E.A., Connor R.E., Fishman I., Armitage B.A. Langmuir. 18:2002;6330.
20. No RLS signal was observed for either Tel11 or Tel12 in the presence of G-quadruplex DNA at wavelengths correlating to the absorbance spectra of these two ligands bound to the G-quadruplex DNA.
21. Ren J., Chaires J.B. Biochemistry. 38:1999;16067.