-
2
-
-
0023663911
-
Telomeric DNA oligonucleotides form intramolecular structures containing guanine-guanine base pairs
-
Henderson E, Hardin CC, Walk SK, Tinoco I Jr, Blackburn EH. 1987. Telomeric DNA oligonucleotides form intramolecular structures containing guanine-guanine base pairs. Cell 51:899-908.
-
(1987)
Cell
, vol.51
, pp. 899-908
-
-
Henderson, E.1
Hardin, C.C.2
Walk, S.K.3
Tinoco Jr, I.4
Blackburn, E.H.5
-
3
-
-
0024843757
-
Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops
-
Sundquist WI, Klug A. 1989. Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops. Nature 342:825-829.
-
(1989)
Nature
, vol.342
, pp. 825-829
-
-
Sundquist, W.I.1
Klug, A.2
-
4
-
-
0024787884
-
Monovalent cation-induced structure of telomeric DNA: The G-quartet model
-
Williamson JR, Raghuraman MK, Cech TR. 1989. Monovalent cation-induced structure of telomeric DNA: the G-quartet model. Cell 59:871-880.
-
(1989)
Cell
, vol.59
, pp. 871-880
-
-
Williamson, J.R.1
Raghuraman, M.K.2
Cech, T.R.3
-
5
-
-
20144364292
-
Prevalence of quadruplexes in the human genome
-
Huppert JL, Balasubramanian S. 2005. Prevalence of quadruplexes in the human genome. Nucleic Acids Res 33:2908-2916.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2908-2916
-
-
Huppert, J.L.1
Balasubramanian, S.2
-
6
-
-
20144369806
-
Highly prevalent putative quadruplex sequence motifs in human DNA
-
Todd AK, Johnston M, Neidle S. 2005. Highly prevalent putative quadruplex sequence motifs in human DNA. Nucleic Acids Res 33:2901-2907.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2901-2907
-
-
Todd, A.K.1
Johnston, M.2
Neidle, S.3
-
7
-
-
0015844590
-
Theory of Marginotomy - Incomplete Copying of Template Margin in Enzymic-Synthesis of Polynucleotides and Biological Significance of Phenomenon
-
Olovnikov AM. 1973. Theory of Marginotomy - Incomplete Copying of Template Margin in Enzymic-Synthesis of Polynucleotides and Biological Significance of Phenomenon. Journal of Theoretical Biology 41:181-190.
-
(1973)
Journal of Theoretical Biology
, vol.41
, pp. 181-190
-
-
Olovnikov, A.M.1
-
8
-
-
0021151105
-
The molecular structure of centromeres and telomeres
-
Blackburn EH. 1984. The molecular structure of centromeres and telomeres. Annu Rev Biochem 53:163-194.
-
(1984)
Annu Rev Biochem
, vol.53
, pp. 163-194
-
-
Blackburn, E.H.1
-
9
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
Greider CW, Blackburn EH. 1985. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43:405-413.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
10
-
-
0025021235
-
Functional evidence for an RNA template in telomerase
-
Shippen-Lentz D, Blackburn EH. 1990. Functional evidence for an RNA template in telomerase. Science 247:546-552.
-
(1990)
Science
, vol.247
, pp. 546-552
-
-
Shippen-Lentz, D.1
Blackburn, E.H.2
-
11
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay JW, Bacchetti S. 1997. A survey of telomerase activity in human cancer. Eur J Cancer 33:787-791.
-
(1997)
Eur J Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
13
-
-
0027220845
-
The subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA
-
Fang G, Cech TR. 1993. The subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA. Cell 74:875-885.
-
(1993)
Cell
, vol.74
, pp. 875-885
-
-
Fang, G.1
Cech, T.R.2
-
14
-
-
0028146763
-
Promotion of parallel DNA quadruplexes by a yeast telomere binding protein: A circular dichroism study
-
Giraldo R, Suzuki M, Chapman L, Rhodes D. 1994. Promotion of parallel DNA quadruplexes by a yeast telomere binding protein: A circular dichroism study. Proc Natl Acad Sci USA 91:7658-7662.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7658-7662
-
-
Giraldo, R.1
Suzuki, M.2
Chapman, L.3
Rhodes, D.4
-
15
-
-
0028246339
-
The yeast telomere-binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA
-
Giraldo R, Rhodes D. 1994. The yeast telomere-binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA. EMBO J 13:2411-2420.
-
(1994)
EMBO J
, vol.13
, pp. 2411-2420
-
-
Giraldo, R.1
Rhodes, D.2
-
16
-
-
0025079955
-
Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein
-
Raghuraman MK, Cech TR. 1990. Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein. Nucleic Acids Res 18:4543-4552.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 4543-4552
-
-
Raghuraman, M.K.1
Cech, T.R.2
-
17
-
-
0034671853
-
Interaction of human DNA topoisomerase I with G-quartet structures
-
Arimondo PB, Riou JF, Mergny JL, Tazi J, Sun JS, et al. 2000. Interaction of human DNA topoisomerase I with G-quartet structures. Nucleic Acids Res 28:4832-4838.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 4832-4838
-
-
Arimondo, P.B.1
Riou, J.F.2
Mergny, J.L.3
Tazi, J.4
Sun, J.S.5
-
18
-
-
0033034413
-
High affinity interactions of nucleolin with G-G-paired rDNA
-
Hanakahi LA, Sun H, Maizels N. 1999. High affinity interactions of nucleolin with G-G-paired rDNA. J Biol Chem 274:15908-15912.
-
(1999)
J Biol Chem
, vol.274
, pp. 15908-15912
-
-
Hanakahi, L.A.1
Sun, H.2
Maizels, N.3
-
20
-
-
0032052284
-
Purification, characterization and molecular cloning of TGP1, a novel G-DNA binding protein from Tetrahymena thermophila
-
Lu Q, Schierer T, Kang SG, Henderson E. 1998. Purification, characterization and molecular cloning of TGP1, a novel G-DNA binding protein from Tetrahymena thermophila. Nucleic Acids Res 26:1613-1620.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 1613-1620
-
-
Lu, Q.1
Schierer, T.2
Kang, S.G.3
Henderson, E.4
-
21
-
-
0028174644
-
A protein from Tetrahymena thermophila that specifically binds parallel-stranded G4-DNA
-
Schierer T, Henderson E. 1994. A protein from Tetrahymena thermophila that specifically binds parallel-stranded G4-DNA. Biochemistry 33:2240-2246.
-
(1994)
Biochemistry
, vol.33
, pp. 2240-2246
-
-
Schierer, T.1
Henderson, E.2
-
22
-
-
0034255052
-
Two tetrahymena G-DNA-binding proteins, TGP1 and TGP3, share novel motifs and may play a role in micronuclear division
-
Lu Q, Henderson E. 2000. Two tetrahymena G-DNA-binding proteins, TGP1 and TGP3, share novel motifs and may play a role in micronuclear division. Nucleic Acids Res 28:2993-3001.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 2993-3001
-
-
Lu, Q.1
Henderson, E.2
-
23
-
-
2442506704
-
Meiosis-specific yeast Hop1 protein promotes synapsis of double-stranded DNA helices via the formation of guanine quartets
-
Anuradha S, Muniyappa K. 2004. Meiosis-specific yeast Hop1 protein promotes synapsis of double-stranded DNA helices via the formation of guanine quartets. Nucleic Acids Res 32:2378-2385.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 2378-2385
-
-
Anuradha, S.1
Muniyappa, K.2
-
24
-
-
0033968862
-
Yeast meiosis-specific protein Hop1 binds to G4 DNA and promotes its formation
-
Muniyappa K, Anuradha S, Byers B. 2000. Yeast meiosis-specific protein Hop1 binds to G4 DNA and promotes its formation. Mol Cell Biol 20:1361-1369.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1361-1369
-
-
Muniyappa, K.1
Anuradha, S.2
Byers, B.3
-
25
-
-
0027415286
-
Identification and characterization of a nuclease activity specific for G4 tetrastranded DNA
-
Liu Z, Frantz JD, Gilbert W, Tye BK. 1993. Identification and characterization of a nuclease activity specific for G4 tetrastranded DNA. Proc Natl Acad Sci USA 90:3157-3161.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3157-3161
-
-
Liu, Z.1
Frantz, J.D.2
Gilbert, W.3
Tye, B.K.4
-
26
-
-
0028243751
-
The yeast KEM1 gene encodes a nuclease specific for G4 tetraplex DNA: Implication of in vivo functions for this novel DNA structure
-
Liu Z, Gilbert W. 1994. The yeast KEM1 gene encodes a nuclease specific for G4 tetraplex DNA: implication of in vivo functions for this novel DNA structure. Cell 77:1083-1092.
-
(1994)
Cell
, vol.77
, pp. 1083-1092
-
-
Liu, Z.1
Gilbert, W.2
-
28
-
-
24044481977
-
Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: Implications for replication of telomeric DNA
-
Ghosal G, Muniyappa K. 2005. Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNA. Nucleic Acids Res 33:4692-4703.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4692-4703
-
-
Ghosal, G.1
Muniyappa, K.2
-
29
-
-
23344451160
-
Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro
-
Zaug AJ, Podell ER, Cech TR. 2005. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. Proc Natl Acad Sci USA 102:10864-10869.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10864-10869
-
-
Zaug, A.J.1
Podell, E.R.2
Cech, T.R.3
-
30
-
-
0029010344
-
Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening
-
Liu Z, Lee A, Gilbert W. 1995. Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening. Proc Natl Acad Sci USA 92:6002-6006.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6002-6006
-
-
Liu, Z.1
Lee, A.2
Gilbert, W.3
-
31
-
-
0026353288
-
Molecular and Genetic-Analysis of the Gene Encoding the Saccharomyces-Cerevisiae Strand Exchange Protein Sep1
-
Tishkoff DX, Johnson AW, Kolodner RD. 1991. Molecular and Genetic-Analysis of the Gene Encoding the Saccharomyces-Cerevisiae Strand Exchange Protein Sep1. Molecular and Cellular Biology 11:2593-2608.
-
(1991)
Molecular and Cellular Biology
, vol.11
, pp. 2593-2608
-
-
Tishkoff, D.X.1
Johnson, A.W.2
Kolodner, R.D.3
-
32
-
-
0035870569
-
Substrate-specific inhibition of RecQ helicase
-
Wu X, Maizels N. 2001. Substrate-specific inhibition of RecQ helicase. Nucleic Acids Res 29:1765-1771.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 1765-1771
-
-
Wu, X.1
Maizels, N.2
-
33
-
-
0033135161
-
The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs
-
Sun H, Bennett RJ, Maizels N. 1999. The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs. Nucleic Acids Res 27:1978-1984.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 1978-1984
-
-
Sun, H.1
Bennett, R.J.2
Maizels, N.3
-
34
-
-
0035393720
-
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
-
Mohaghegh P, Karow JK, Brosh RM Jr, Bohr VA, Hickson ID. 2001. The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Res 29:2843-2849.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 2843-2849
-
-
Mohaghegh, P.1
Karow, J.K.2
Brosh Jr, R.M.3
Bohr, V.A.4
Hickson, I.D.5
-
36
-
-
0030765180
-
The SV40 large T-antigen helicase can unwind four stranded DNA structures linked by G-quartets
-
Baran N, Pucshansky L, Marco Y, Benjamin S, Manor H. 1997. The SV40 large T-antigen helicase can unwind four stranded DNA structures linked by G-quartets. Nucleic Acids Res 25:297-303.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 297-303
-
-
Baran, N.1
Pucshansky, L.2
Marco, Y.3
Benjamin, S.4
Manor, H.5
-
38
-
-
2942718760
-
Regulation of murine telomere length by Rtel; an essential gene encoding a helicase-like protein
-
Ding H, Schertzer M, Wu X, Gertsenstein M, Selig S, et al. 2004. Regulation of murine telomere length by Rtel; an essential gene encoding a helicase-like protein. Cell 117:873-886.
-
(2004)
Cell
, vol.117
, pp. 873-886
-
-
Ding, H.1
Schertzer, M.2
Wu, X.3
Gertsenstein, M.4
Selig, S.5
-
39
-
-
0345304903
-
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
-
Lei M, Podell ER, Baumann P, Cech TR. 2003. DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA. Nature 426:198-203.
-
(2003)
Nature
, vol.426
, pp. 198-203
-
-
Lei, M.1
Podell, E.R.2
Baumann, P.3
Cech, T.R.4
-
40
-
-
0035844082
-
Pot1, the putative telomere end-binding protein in fission yeast and humans
-
Baumann P, Cech TR. 2001. Pot1, the putative telomere end-binding protein in fission yeast and humans. Science 292:1171-1175.
-
(2001)
Science
, vol.292
, pp. 1171-1175
-
-
Baumann, P.1
Cech, T.R.2
-
41
-
-
0038413786
-
Human POT1 facilitates telomere elongation by telomerase
-
Colgin LM, Baran K, Baumann P, Cech TR, Reddel RR. 2003. Human POT1 facilitates telomere elongation by telomerase. Curr Biol 13:942-946.
-
(2003)
Curr Biol
, vol.13
, pp. 942-946
-
-
Colgin, L.M.1
Baran, K.2
Baumann, P.3
Cech, T.R.4
Reddel, R.R.5
-
42
-
-
33646894709
-
hnRNP A1 associates with telomere ends and stimulates telomerase activity
-
Zhang QS, Manche L, Xu RM, Krainer AR. 2006. hnRNP A1 associates with telomere ends and stimulates telomerase activity. RNA 12:1116-1128.
-
(2006)
RNA
, vol.12
, pp. 1116-1128
-
-
Zhang, Q.S.1
Manche, L.2
Xu, R.M.3
Krainer, A.R.4
-
43
-
-
21444433242
-
Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by hnRNP D
-
Enokizono Y, Konishi Y, Nagata K, Ouhashi K, Uesugi S, et al. 2005. Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by hnRNP D. J Biol Chem 280:18862-18870.
-
(2005)
J Biol Chem
, vol.280
, pp. 18862-18870
-
-
Enokizono, Y.1
Konishi, Y.2
Nagata, K.3
Ouhashi, K.4
Uesugi, S.5
-
44
-
-
0036790810
-
Unfolding of quadruplex structure in the G-rich strand of the minisatellite repeat by the binding protein UP1
-
Fukuda H, Katahira M, Tsuchiya N, Enokizono Y, Sugimura T, et al. 2002. Unfolding of quadruplex structure in the G-rich strand of the minisatellite repeat by the binding protein UP1. Proc Natl Acad Sci USA 99:12685-12690.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12685-12690
-
-
Fukuda, H.1
Katahira, M.2
Tsuchiya, N.3
Enokizono, Y.4
Sugimura, T.5
-
45
-
-
0034640507
-
Heterogeneous nuclear ribonucleoprotein A1 and UP1 protect mammalian telomeric repeats and modulate telomere replication in vitro
-
Dallaire F, Dupuis S, Fiset S, Chabot B. 2000. Heterogeneous nuclear ribonucleoprotein A1 and UP1 protect mammalian telomeric repeats and modulate telomere replication in vitro. J Biol Chem 275:14509-14516.
-
(2000)
J Biol Chem
, vol.275
, pp. 14509-14516
-
-
Dallaire, F.1
Dupuis, S.2
Fiset, S.3
Chabot, B.4
-
46
-
-
0035902465
-
In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei
-
Schaffitzel C, Berger I, Postberg J, Hanes J, Lipps HJ, et al. 2001. In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei. Proc Natl Acad Sci USA 98:8572-8577.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8572-8577
-
-
Schaffitzel, C.1
Berger, I.2
Postberg, J.3
Hanes, J.4
Lipps, H.J.5
-
47
-
-
27144451010
-
Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo
-
Paeschke K, Simonsson T, Postberg J, Rhodes D, Lipps HJ. 2005. Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo. Nat Struct Mol Biol 12:847-854.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 847-854
-
-
Paeschke, K.1
Simonsson, T.2
Postberg, J.3
Rhodes, D.4
Lipps, H.J.5
-
48
-
-
3042785608
-
Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA
-
Duquette ML, Handa P, Vincent JA, Taylor AF, Maizels N. 2004. Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA. Genes Dev 18:1618-1629.
-
(2004)
Genes Dev
, vol.18
, pp. 1618-1629
-
-
Duquette, M.L.1
Handa, P.2
Vincent, J.A.3
Taylor, A.F.4
Maizels, N.5
-
49
-
-
23044460408
-
Preferential binding of a G-quadruplex ligand to human chromosome ends
-
Granotier C, Pennarun G, Riou L, Hoffschir F, Gauthier LR, et al. 2005. Preferential binding of a G-quadruplex ligand to human chromosome ends. Nucleic Acids Res 33:4182-4190.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4182-4190
-
-
Granotier, C.1
Pennarun, G.2
Riou, L.3
Hoffschir, F.4
Gauthier, L.R.5
-
50
-
-
0025269255
-
A sodium-potassium switch in the formation of four-stranded G4-DNA
-
Sen D, Gilbert W. 1990. A sodium-potassium switch in the formation of four-stranded G4-DNA. Nature 344:410-414.
-
(1990)
Nature
, vol.344
, pp. 410-414
-
-
Sen, D.1
Gilbert, W.2
-
51
-
-
0029071176
-
A phase diagram for sodium and potassium ion control of polymorphism in telomeric DNA
-
Miura T, Benevides JM, Thomas GJ Jr. 1995. A phase diagram for sodium and potassium ion control of polymorphism in telomeric DNA. J Mol Biol 248:233-238.
-
(1995)
J Mol Biol
, vol.248
, pp. 233-238
-
-
Miura, T.1
Benevides, J.M.2
Thomas Jr., G.J.3
-
52
-
-
12344282204
-
Organization and pairing of meiotic chromosomes in the ciliate Tetrahymena thermophila
-
Loidl J, Scherthan H. 2004. Organization and pairing of meiotic chromosomes in the ciliate Tetrahymena thermophila. J Cell Sci 117:5791-5801.
-
(2004)
J Cell Sci
, vol.117
, pp. 5791-5801
-
-
Loidl, J.1
Scherthan, H.2
-
54
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
Griffith JD, Comeau L, Rosenfield S, Stansel RM, Bianchi A, et al. 1999. Mammalian telomeres end in a large duplex loop. Cell 97:503-514.
-
(1999)
Cell
, vol.97
, pp. 503-514
-
-
Griffith, J.D.1
Comeau, L.2
Rosenfield, S.3
Stansel, R.M.4
Bianchi, A.5
-
55
-
-
0036832737
-
Opinion: Telomere maintenance and cancer - look, no telomerase
-
Neumann AA, Reddel RR. 2002. Opinion: Telomere maintenance and cancer - look, no telomerase. Nat Rev Cancer 2:879-884.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 879-884
-
-
Neumann, A.A.1
Reddel, R.R.2
-
56
-
-
0034176194
-
G-quadruplex DNA: A potential target for anticancer drug design
-
Han H, Hurley LH. 2000. G-quadruplex DNA: a potential target for anticancer drug design. Trends Pharmacol Sci 21:136-142.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 136-142
-
-
Han, H.1
Hurley, L.H.2
-
57
-
-
29044436682
-
3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex
-
Zhang N, Phan AT, Patel DJ. 2005. (3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex. J Am Chem Soc 127:17277-17285.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 17277-17285
-
-
Zhang, N.1
Phan, A.T.2
Patel, D.J.3
-
58
-
-
0020322524
-
Higher order DNA structure in macronuclear chromatin of the hypotrichous ciliate Oxytricha nova
-
Lipps HJ, Gruissem W, Prescott DM. 1982. Higher order DNA structure in macronuclear chromatin of the hypotrichous ciliate Oxytricha nova. Proc Natl Acad Sci USA 79:2495-2499.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 2495-2499
-
-
Lipps, H.J.1
Gruissem, W.2
Prescott, D.M.3
-
59
-
-
0023788886
-
Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis
-
Sen D, Gilbert W. 1988. Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis. Nature 334:364-366.
-
(1988)
Nature
, vol.334
, pp. 364-366
-
-
Sen, D.1
Gilbert, W.2
-
60
-
-
33745612968
-
The new models of the human telomere d[AGGG(TTAGGG)(3)] in K(+) solution
-
Xu Y, Noguchi Y, Sugiyama H. 2006. The new models of the human telomere d[AGGG(TTAGGG)(3)] in K(+) solution. Bioorg Med Chem 14:5584-5591.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 5584-5591
-
-
Xu, Y.1
Noguchi, Y.2
Sugiyama, H.3
-
61
-
-
33646943863
-
Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution
-
Ambrus A, Chen D, Dai J, Bialis T, Jones RA, et al. 2006. Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution. Nucleic Acids Res 34:2723-2735.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 2723-2735
-
-
Ambrus, A.1
Chen, D.2
Dai, J.3
Bialis, T.4
Jones, R.A.5
-
62
-
-
0037142071
-
Crystal structure of parallel quadruplexes from human telomeric DNA
-
Parkinson GN, Lee MP, Neidle S. 2002. Crystal structure of parallel quadruplexes from human telomeric DNA. Nature 417:876-880.
-
(2002)
Nature
, vol.417
, pp. 876-880
-
-
Parkinson, G.N.1
Lee, M.P.2
Neidle, S.3
-
63
-
-
0027918585
-
Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex
-
Wang Y, Patel DJ. 1993. Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex. Structure 1:263-282.
-
(1993)
Structure
, vol.1
, pp. 263-282
-
-
Wang, Y.1
Patel, D.J.2
-
64
-
-
23844438712
-
Not so crystal clear: The structure of the human telomere G-quadruplex in solution differs from that present in a crystal
-
Li J, Correia JJ, Wang L, Trent JO, Chaires JB. 2005. Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal. Nucleic Acids Res 33:4649-4659.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4649-4659
-
-
Li, J.1
Correia, J.J.2
Wang, L.3
Trent, J.O.4
Chaires, J.B.5
-
65
-
-
0344304471
-
Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer
-
Ying L, Green JJ, Li H, Klenerman D, Balasubramanian S. 2003. Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer. Proc Natl Acad Sci USA 100:14629-14634.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14629-14634
-
-
Ying, L.1
Green, J.J.2
Li, H.3
Klenerman, D.4
Balasubramanian, S.5
-
66
-
-
30044448463
-
Extreme conformational diversity in human telomeric DNA
-
Lee JY, Okumus B, Kim DS, Ha T. 2005. Extreme conformational diversity in human telomeric DNA. Proc Natl Acad Sci USA 102:18938-18943.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18938-18943
-
-
Lee, J.Y.1
Okumus, B.2
Kim, D.S.3
Ha, T.4
-
67
-
-
33746600695
-
Structure of the human telomere in k(+) solution: An intramolecular (3 + 1) g-quadruplex scaffold
-
Luu KN, Phan AT, Kuryavyi V, Lacroix L, Patel DJ. 2006. Structure of the human telomere in k(+) solution: an intramolecular (3 + 1) g-quadruplex scaffold. J Am Chem Soc 128:9963-9970.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 9963-9970
-
-
Luu, K.N.1
Phan, A.T.2
Kuryavyi, V.3
Lacroix, L.4
Patel, D.J.5
-
68
-
-
0026687030
-
Guanine residues in d(T2AG3) and d(T2G4) form parallel-stranded potassium cation stabilized G-quadruplexes with anti glycosidic torsion angles in solution
-
Wang Y, Patel DJ. 1992. Guanine residues in d(T2AG3) and d(T2G4) form parallel-stranded potassium cation stabilized G-quadruplexes with anti glycosidic torsion angles in solution. Biochemistry 31:8112-8119.
-
(1992)
Biochemistry
, vol.31
, pp. 8112-8119
-
-
Wang, Y.1
Patel, D.J.2
-
69
-
-
0345098322
-
Two-repeat human telomeric d(TAGGGT-TAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: Distinct topologies, thermodynamic properties, and folding/unfolding kinetics
-
Phan AT, Patel DJ. 2003. Two-repeat human telomeric d(TAGGGT-TAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics. J Am Chem Soc 125:15021-15027.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 15021-15027
-
-
Phan, A.T.1
Patel, D.J.2
-
70
-
-
0030786928
-
Inhibition of human telomerase by a G-quadruplex-interactive compound
-
Sun D, Thompson B, Cathers BE, Salazar M, Kerwin SM, et al. 1997. Inhibition of human telomerase by a G-quadruplex-interactive compound. J Med Chem 40:2113-2116.
-
(1997)
J Med Chem
, vol.40
, pp. 2113-2116
-
-
Sun, D.1
Thompson, B.2
Cathers, B.E.3
Salazar, M.4
Kerwin, S.M.5
-
71
-
-
0032495774
-
Cationic porphyrins as telomerase inhibitors: The interaction of tetra-(N-methyl-4- pyridyl)porphine with quadruplex DNA
-
Wheelhouse RT, Sun DK, Han HY, Han FX, Hurley LH. 1998. Cationic porphyrins as telomerase inhibitors: the interaction of tetra-(N-methyl-4- pyridyl)porphine with quadruplex DNA. J Am Chem Soc 120:3261-3262.
-
(1998)
J Am Chem Soc
, vol.120
, pp. 3261-3262
-
-
Wheelhouse, R.T.1
Sun, D.K.2
Han, H.Y.3
Han, F.X.4
Hurley, L.H.5
-
72
-
-
10644290098
-
Selective interactions of perylene derivatives having different side chains with inter- and intramolecular G-quadruplex DNA structures. A correlation with telomerase inhibition
-
Rossetti L, Franceschin M, Schirripa S, Bianco A, Ortaggi G, et al. 2005. Selective interactions of perylene derivatives having different side chains with inter- and intramolecular G-quadruplex DNA structures. A correlation with telomerase inhibition. Bioorg Med Chem Lett 15:413-420.
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 413-420
-
-
Rossetti, L.1
Franceschin, M.2
Schirripa, S.3
Bianco, A.4
Ortaggi, G.5
-
73
-
-
0035942270
-
Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors
-
Read M, Harrison RJ, Romagnoli B, Tanious FA, Gowan SH, et al. 2001. Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors. Proc Natl Acad Sci USA 98:4844-4849.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4844-4849
-
-
Read, M.1
Harrison, R.J.2
Romagnoli, B.3
Tanious, F.A.4
Gowan, S.H.5
-
74
-
-
0036241599
-
A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity
-
Gowan SM, Harrison JR, Patterson L, Valenti M, Read MA, et al. 2002. A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity. Mol Pharmacol 61:1154-1162.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 1154-1162
-
-
Gowan, S.M.1
Harrison, J.R.2
Patterson, L.3
Valenti, M.4
Read, M.A.5
-
75
-
-
0034760505
-
Potent inhibition of telomerase by small-molecule pentacyclie acridines capable of interacting with g-quadruplexes
-
Gowan SM, Heald R, Stevens MF, Kelland LR. 2001. Potent inhibition of telomerase by small-molecule pentacyclie acridines capable of interacting with g-quadruplexes. Mol Pharmacol 60:981-988.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 981-988
-
-
Gowan, S.M.1
Heald, R.2
Stevens, M.F.3
Kelland, L.R.4
-
76
-
-
0035857396
-
Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus
-
Shin-Ya K, Wierzba K, Matsuo K, Ohtani T, Yamada Y, et al. 2001. Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus. J Am Chem Soc 123:1262-1263.
-
(2001)
J Am Chem Soc
, vol.123
, pp. 1262-1263
-
-
Shin-Ya, K.1
Wierzba, K.2
Matsuo, K.3
Ohtani, T.4
Yamada, Y.5
-
77
-
-
0035853164
-
Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay
-
Mergny JL, Lacroix L, Teulade-Fichou MP, Hounsou C, Guittat L, et al. 2001. Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay. Proc Natl Acad Sci USA 98:3062-3067.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3062-3067
-
-
Mergny, J.L.1
Lacroix, L.2
Teulade-Fichou, M.P.3
Hounsou, C.4
Guittat, L.5
-
78
-
-
0035282707
-
Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes
-
Koeppel F, Riou JF, Laoui A, Mailliet P, Arimondo PB, et al. 2001. Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes. Nucleic Acids Res 29:1087-1096.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 1087-1096
-
-
Koeppel, F.1
Riou, J.F.2
Laoui, A.3
Mailliet, P.4
Arimondo, P.B.5
-
79
-
-
0037022658
-
Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands
-
Riou JF, Guittat L, Mailliet P, Laoui A, Renou E, et al. 2002. Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands. Proc Natl Acad Sci USA 99:2672-2677.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2672-2677
-
-
Riou, J.F.1
Guittat, L.2
Mailliet, P.3
Laoui, A.4
Renou, E.5
-
80
-
-
0035553175
-
Design and synthesis of fluoroquinophenoxazines that interact with human telomerie G-quadruplexes and their biological effects
-
Duan W, Rangan A, Vankayalapati H, Kim MY, Zeng Q, et al. 2001. Design and synthesis of fluoroquinophenoxazines that interact with human telomerie G-quadruplexes and their biological effects. Mol Cancer Ther 1:103-120.
-
(2001)
Mol Cancer Ther
, vol.1
, pp. 103-120
-
-
Duan, W.1
Rangan, A.2
Vankayalapati, H.3
Kim, M.Y.4
Zeng, Q.5
-
81
-
-
31544441946
-
Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines
-
Zhou JM, Zhu XF, Lu YJ, Deng R, Huang ZS, et al. 2005. Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines. Oncogene 25:503-511.
-
(2005)
Oncogene
, vol.25
, pp. 503-511
-
-
Zhou, J.M.1
Zhu, X.F.2
Lu, Y.J.3
Deng, R.4
Huang, Z.S.5
-
82
-
-
6344292236
-
Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes
-
Patel SD, Isalan M, Gavory G, Ladame S, Choo Y, et al. 2004. Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes. Biochemistry 43:13452-13458.
-
(2004)
Biochemistry
, vol.43
, pp. 13452-13458
-
-
Patel, S.D.1
Isalan, M.2
Gavory, G.3
Ladame, S.4
Choo, Y.5
-
83
-
-
0035352382
-
DNA tetraplex-binding drugs: Structure-selective targeting is critical for antitumour telomerase inhibition
-
Perry PJ, Jenkins TC. 2001. DNA tetraplex-binding drugs: structure-selective targeting is critical for antitumour telomerase inhibition. Mini Rev Med Chem 1:31-41.
-
(2001)
Mini Rev Med Chem
, vol.1
, pp. 31-41
-
-
Perry, P.J.1
Jenkins, T.C.2
-
84
-
-
0037889841
-
Telomere inhibition and telomere disruption as processes for drug targeting
-
Rezler EM, Bearss DJ, Hurley LH. 2003. Telomere inhibition and telomere disruption as processes for drug targeting. Annu Rev Pharmacol Toxicol 43:359-379.
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 359-379
-
-
Rezler, E.M.1
Bearss, D.J.2
Hurley, L.H.3
-
85
-
-
4444304085
-
G-quadruplex interacting agents targeting the telomeric g-overhang are more than simple telomerase inhibitors
-
Riou JF. 2004. G-quadruplex interacting agents targeting the telomeric g-overhang are more than simple telomerase inhibitors. Curr Med Chem Anti-Canc Agents 4:439-443.
-
(2004)
Curr Med Chem Anti-Canc Agents
, vol.4
, pp. 439-443
-
-
Riou, J.F.1
-
86
-
-
18044391665
-
Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics - current status and future prospects
-
Kelland LR. 2005. Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics - current status and future prospects. Eur J Cancer 41:971-979.
-
(2005)
Eur J Cancer
, vol.41
, pp. 971-979
-
-
Kelland, L.R.1
-
87
-
-
0037070575
-
Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex
-
Kim MY, Vankayalapati H, Shin-Ya K, Wierzba K, Hurley LH. 2002. Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex. J Am Chem Soc 124:2098-2099.
-
(2002)
J Am Chem Soc
, vol.124
, pp. 2098-2099
-
-
Kim, M.Y.1
Vankayalapati, H.2
Shin-Ya, K.3
Wierzba, K.4
Hurley, L.H.5
-
88
-
-
21644460419
-
Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure
-
Rezler EM, Seenisamy J, Bashyam S, Kim MY, White E, et al. 2005. Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure. J Am Chem Soc 127:9439-9447.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 9439-9447
-
-
Rezler, E.M.1
Seenisamy, J.2
Bashyam, S.3
Kim, M.Y.4
White, E.5
-
89
-
-
0242609879
-
Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry
-
Rosu F, Gabelica V, Shin-Ya K, De Pauw E. 2003. Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry. Chem Commun (Camb) 21:2702-2703.
-
(2003)
Chem Commun (Camb)
, vol.21
, pp. 2702-2703
-
-
Rosu, F.1
Gabelica, V.2
Shin-Ya, K.3
De Pauw, E.4
-
90
-
-
0037731436
-
The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures
-
Kim MY, Gleason-Guzman M, Izbicka E, Nishioka D, Hurley LH. 2003. The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures. Cancer Res 63:3247-3256.
-
(2003)
Cancer Res
, vol.63
, pp. 3247-3256
-
-
Kim, M.Y.1
Gleason-Guzman, M.2
Izbicka, E.3
Nishioka, D.4
Hurley, L.H.5
-
91
-
-
0842289983
-
Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma
-
Shammas MA, Reis RJ, Li C, Koley H, Hurley LH, et al. 2004. Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma. Clin Cancer Res 10:770-776.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 770-776
-
-
Shammas, M.A.1
Reis, R.J.2
Li, C.3
Koley, H.4
Hurley, L.H.5
-
92
-
-
33748701981
-
Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: In vitro and in vivo studies in acute leukemia
-
Tauchi T, Shin-Ya K, Sashida G, Sumi M, Okabe S, et al. 2006. Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia. Oncogene 25:5719-5725.
-
(2006)
Oncogene
, vol.25
, pp. 5719-5725
-
-
Tauchi, T.1
Shin-Ya, K.2
Sashida, G.3
Sumi, M.4
Okabe, S.5
-
93
-
-
33645280314
-
G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells
-
Tahara H, Shin-Ya K, Seimiya H, Yamada H, Tsuruo T, et al. 2006. G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells. Oncogene 25: 1955-1966.
-
(2006)
Oncogene
, vol.25
, pp. 1955-1966
-
-
Tahara, H.1
Shin-Ya, K.2
Seimiya, H.3
Yamada, H.4
Tsuruo, T.5
-
94
-
-
0041353443
-
Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: Involvement of ATM-dependent DNA damage response pathways
-
Tauchi T, Shin-Ya K, Sashida G, Sumi M, Nakajima A, et al. 2003. Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways. Oncogene 22:5338-5347.
-
(2003)
Oncogene
, vol.22
, pp. 5338-5347
-
-
Tauchi, T.1
Shin-Ya, K.2
Sashida, G.3
Sumi, M.4
Nakajima, A.5
-
95
-
-
4744357958
-
Interaction of telomestatin with the telomeric single-strand overhang
-
Gomez D, Paterski R, Lemarteleur T, Shin-Ya K, Mergny JL, et al. 2004. Interaction of telomestatin with the telomeric single-strand overhang. J Biol Chem 279:41487-41494.
-
(2004)
J Biol Chem
, vol.279
, pp. 41487-41494
-
-
Gomez, D.1
Paterski, R.2
Lemarteleur, T.3
Shin-Ya, K.4
Mergny, J.L.5
-
96
-
-
33746916385
-
The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells
-
Gomez D, O'Donohue MF, Wenner T, Douarre C, Macadre J, et al. 2006. The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells. Cancer Res 66:6908-6912.
-
(2006)
Cancer Res
, vol.66
, pp. 6908-6912
-
-
Gomez, D.1
O'Donohue, M.F.2
Wenner, T.3
Douarre, C.4
Macadre, J.5
-
97
-
-
7444237059
-
A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells
-
Incles CM, Schultes CM, Kempski H, Koehler H, Kelland LR, et al. 2004. A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells. Mol Cancer Ther 3:1201-1206.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1201-1206
-
-
Incles, C.M.1
Schultes, C.M.2
Kempski, H.3
Koehler, H.4
Kelland, L.R.5
-
98
-
-
13944272246
-
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function
-
Burger AM, Dai F, Schultes CM, Reszka AP, Moore MJ, et al. 2005. The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function. Cancer Res 65:1489-1496.
-
(2005)
Cancer Res
, vol.65
, pp. 1489-1496
-
-
Burger, A.M.1
Dai, F.2
Schultes, C.M.3
Reszka, A.P.4
Moore, M.J.5
-
99
-
-
1242342930
-
Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing
-
Gomez D, Lemarteleur T, Lacroix L, Mailliet P, Mergny JL, et al. 2004. Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing. Nucleic Acids Res 32:371-379.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 371-379
-
-
Gomez, D.1
Lemarteleur, T.2
Lacroix, L.3
Mailliet, P.4
Mergny, J.L.5
-
100
-
-
0037015078
-
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
-
Siddiqui-Jain A, Grand CL, Bearss DJ, Hurley LH. 2002. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proc Natl Acad Sci USA 99:11593-11598.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11593-11598
-
-
Siddiqui-Jain, A.1
Grand, C.L.2
Bearss, D.J.3
Hurley, L.H.4
|