A quantitative assay of telomerase activity

Pharmaceutical Research

Volumn 18, Issue 4, 2001, Pages 488-493

  Gan, Y ^a   Lu, J ^a   Johnson, A ^a   Wientjes, M G ^a,b   Schuller, D E ^a,b   Au, J L S ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Inhibitor; Telomerase; Telomerase assay; TRAP

Indexed keywords

ETHIDIUM BROMIDE; PRIMER DNA; TELOMERASE;

ACCURACY; ARTICLE; AUTORADIOGRAPHY; CANCER CELL CULTURE; CELL VIABILITY; CHROMOSOME; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; GENE AMPLIFICATION; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; METHODOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TELOMERE; VALIDATION PROCESS;

BIOLOGICAL ASSAY; HUMANS; POLYMERASE CHAIN REACTION; TELOMERASE; TUMOR CELLS, CULTURED;

EID: 0034948445     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011006427733     Document Type: Article

References (15)

1. Role of telomerase in cell senescence and oncogenesis
2. Anti-apoptosis role of telomerase in pheochromocytoma cells
3. Telomere maintenance is dependent on activities required for end repair of double-strand breaks
4. Telomerase enzyme activity and RNA expression in adriamycin-resistant human breast carcinoma MCF-7 cells
5. Specific association of human telomerase activity with immortal cells and cancer
6. Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity
7. Advances in qualification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP)
8. New method to measure telomerase activity by transcription-mediated amplification and hybridization protection assay
9. Simplified method for the telomeric repeat amplification protocol (TRAP)
10. Rapid, quantitative nonisotopic assay for telomerase activity in human tumors
11. Non-radioactive semiquantitative testing for expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological behaviour
12. Detection of telomerase activity in human cells and tumors. Telomerase repeat amplification protocol (TRAP)
13. Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3′-azido-3′-deoxythymidine
14. Limitations on the quantitative determination of telomerase activity by the electrophoretic and ELISA based TRAP assays
15. Regulation of catalytic activity and processicity of human telometase