Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells

Cancer Letters

Volumn 250, Issue 1, 2007, Pages 63-73

  Zhang, Ying ^a   Zhou, Junqing ^a   Cao, Xiaofan ^a   Zhang, Qinming ^a   Lim, Chang U K ^b   Ullrich, Robert L ^a,c   Bailey, Susan M ^a,c   Liber, Howard L ^a,c  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b ORDWAY RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

DNA PKcs; Ionizing radiation; Mutagenesis; Partial deficiency; Telomere

Indexed keywords

DNA DEPENDENT PROTEIN KINASE; KU ANTIGEN; SMALL INTERFERING RNA;

ARTICLE; CANCER SUSCEPTIBILITY; CELL CULTURE; CELL FUNCTION; CELL KILLING; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA BINDING; DNA REPAIR; GENE MUTATION; GENETIC STABILITY; GENETIC TRANSFECTION; HETEROZYGOTE; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IONIZING RADIATION; MUTAGENESIS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; TELOMERE;

CELL LINE; DNA-ACTIVATED PROTEIN KINASE; GENOMIC INSTABILITY; HUMANS; LYMPHOCYTES; MUTAGENESIS; RADIATION, IONIZING; TELOMERE; TRANSFECTION;

ANIMALIA; EUKARYOTA;

EID: 33947591135     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2006.09.021     Document Type: Article

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