-
1
-
-
33748359678
-
Questions linger about unexplained gene-therapy trial death
-
Abbott A. Questions linger about unexplained gene-therapy trial death. Nat. Med. 12 (2006) 597
-
(2006)
Nat. Med.
, vol.12
, pp. 597
-
-
Abbott, A.1
-
2
-
-
0035503241
-
A midline promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging
-
Adachi Y., Reynolds P.N., Yamamoto M., Wang M., Takayama K., Matsubara S., et al. A midline promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging. Cancer Res. 61 (2001) 7882-7888
-
(2001)
Cancer Res.
, vol.61
, pp. 7882-7888
-
-
Adachi, Y.1
Reynolds, P.N.2
Yamamoto, M.3
Wang, M.4
Takayama, K.5
Matsubara, S.6
-
3
-
-
24944522335
-
Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders
-
Arkin L.M., Sondhi D., Worgall S., Suh L.H., Hackett N.R., Kaminsky S.M., et al. Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders. Hum. Gene Ther. 16 (2005) 1028-1036
-
(2005)
Hum. Gene Ther.
, vol.16
, pp. 1028-1036
-
-
Arkin, L.M.1
Sondhi, D.2
Worgall, S.3
Suh, L.H.4
Hackett, N.R.5
Kaminsky, S.M.6
-
4
-
-
0041700123
-
Neoadjuvant chemotherapy for osteosarcoma of the extremities with metastases at presentation: recent experience at the Rizzoli Institute in 57 patients treated with cisplatin, doxorubicin, and a high dose of methotrexate and ifosfamide
-
Bacci G., Briccoli A., Rocca M., Ferrari S., Donati D., Longhi A., et al. Neoadjuvant chemotherapy for osteosarcoma of the extremities with metastases at presentation: recent experience at the Rizzoli Institute in 57 patients treated with cisplatin, doxorubicin, and a high dose of methotrexate and ifosfamide. Ann. Oncol. 14 (2003) 1126-1134
-
(2003)
Ann. Oncol.
, vol.14
, pp. 1126-1134
-
-
Bacci, G.1
Briccoli, A.2
Rocca, M.3
Ferrari, S.4
Donati, D.5
Longhi, A.6
-
5
-
-
0036764768
-
Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells
-
Barnett B.G., Tillman B.W., Curiel D.T., and Douglas J.T. Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells. Mol. Ther. 6 (2002) 377-385
-
(2002)
Mol. Ther.
, vol.6
, pp. 377-385
-
-
Barnett, B.G.1
Tillman, B.W.2
Curiel, D.T.3
Douglas, J.T.4
-
6
-
-
0030611932
-
Altered G1 phase regulation in osteosarcoma
-
Benassi M.S., Molendini L., Gamberi G., Sollazzo M.R., Ragazzini P., Merli M., et al. Altered G1 phase regulation in osteosarcoma. Int. J. Cancer 74 (1997) 518-522
-
(1997)
Int. J. Cancer
, vol.74
, pp. 518-522
-
-
Benassi, M.S.1
Molendini, L.2
Gamberi, G.3
Sollazzo, M.R.4
Ragazzini, P.5
Merli, M.6
-
7
-
-
0035839440
-
A phase I/II dose escalation and activity study of intravenous injections of OCaP1 for subjects with refractory osteosarcoma metastatic to lung
-
Benjamin R., Helman L., Meyers P., and Reaman G. A phase I/II dose escalation and activity study of intravenous injections of OCaP1 for subjects with refractory osteosarcoma metastatic to lung. Hum. Gene Ther. 12 (2001) 1591-1593
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 1591-1593
-
-
Benjamin, R.1
Helman, L.2
Meyers, P.3
Reaman, G.4
-
8
-
-
0031052263
-
Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
-
Bergelson J.M., Cunningham J.A., Droguett G., Kurt-Jones E.A., Krithivas A., Hong J.S., et al. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science 275 (1997) 1320-1323
-
(1997)
Science
, vol.275
, pp. 1320-1323
-
-
Bergelson, J.M.1
Cunningham, J.A.2
Droguett, G.3
Kurt-Jones, E.A.4
Krithivas, A.5
Hong, J.S.6
-
9
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff J.R., Kirn D.H., Williams A., Heise C., Horn S., Muna M., et al. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 274 (1996) 373-376
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
Heise, C.4
Horn, S.5
Muna, M.6
-
10
-
-
0032781072
-
Retargeting to EGFR enhances adenovirus infection efficiency of squamous cell carcinoma
-
Blackwell J.L., Miller C.R., Douglas J.T., Li H., Reynolds P.N., Carroll W.R., et al. Retargeting to EGFR enhances adenovirus infection efficiency of squamous cell carcinoma. Arch. Otolaryngol., Head Neck Surg. 125 (1999) 856-863
-
(1999)
Arch. Otolaryngol., Head Neck Surg.
, vol.125
, pp. 856-863
-
-
Blackwell, J.L.1
Miller, C.R.2
Douglas, J.T.3
Li, H.4
Reynolds, P.N.5
Carroll, W.R.6
-
11
-
-
84944972302
-
Congenital telangiectatic erythema resembling lupus erythematosus in dwarfs; probably a syndrome entity
-
Bloom D. Congenital telangiectatic erythema resembling lupus erythematosus in dwarfs; probably a syndrome entity. AMA Am. J. Dis. Child. 88 (1954) 754-758
-
(1954)
AMA Am. J. Dis. Child.
, vol.88
, pp. 754-758
-
-
Bloom, D.1
-
12
-
-
0034666240
-
Recombinant viruses as a tool for therapeutic vaccination against human cancers
-
Bonnet M.C., Tartaglia J., Verdier F., Kourilsky P., Lindberg A., Klein M., et al. Recombinant viruses as a tool for therapeutic vaccination against human cancers. Immunol. Lett. 74 (2000) 11-25
-
(2000)
Immunol. Lett.
, vol.74
, pp. 11-25
-
-
Bonnet, M.C.1
Tartaglia, J.2
Verdier, F.3
Kourilsky, P.4
Lindberg, A.5
Klein, M.6
-
13
-
-
0037790709
-
Immune responses to replication-defective HSV-1 type vectors within the CNS: implications for gene therapy
-
Bowers W.J., Olschowka J.A., and Federoff H.J. Immune responses to replication-defective HSV-1 type vectors within the CNS: implications for gene therapy. Gene Ther. 10 (2003) 941-945
-
(2003)
Gene Ther.
, vol.10
, pp. 941-945
-
-
Bowers, W.J.1
Olschowka, J.A.2
Federoff, H.J.3
-
14
-
-
0037103167
-
Dangerous liaisons: the role of "danger" signals in the immune response to gene therapy
-
Brown B.D., and Lillicrap D. Dangerous liaisons: the role of "danger" signals in the immune response to gene therapy. Blood 100 (2002) 1133-1140
-
(2002)
Blood
, vol.100
, pp. 1133-1140
-
-
Brown, B.D.1
Lillicrap, D.2
-
15
-
-
0032949872
-
Treatment of experimental osteosarcoma tumors in rat by herpes simplex thymidine kinase gene transfer and ganciclovir
-
Charissoux J.L., Grossin L., Leboutet M.J., and Rigaud M. Treatment of experimental osteosarcoma tumors in rat by herpes simplex thymidine kinase gene transfer and ganciclovir. Anticancer Res. 19 (1999) 77-80
-
(1999)
Anticancer Res.
, vol.19
, pp. 77-80
-
-
Charissoux, J.L.1
Grossin, L.2
Leboutet, M.J.3
Rigaud, M.4
-
16
-
-
0038128343
-
Adaptive and innate immune responses to gene transfer vectors: role of cytokines and chemokines in vector function
-
Chen D., Murphy B., Sung R., and Bromberg J.S. Adaptive and innate immune responses to gene transfer vectors: role of cytokines and chemokines in vector function. Gene Ther. 10 (2003) 991-998
-
(2003)
Gene Ther.
, vol.10
, pp. 991-998
-
-
Chen, D.1
Murphy, B.2
Sung, R.3
Bromberg, J.S.4
-
17
-
-
0034025738
-
Adenovirus-mediated suicide-gene therapy using the herpes simplex virus thymidine kinase gene in cell and animal models of human prostate cancer: changes in tumour cell proliferative activity
-
Cheon J., Kim H.K., Moon D.G., Yoon D.K., Cho J.H., and Koh S.K. Adenovirus-mediated suicide-gene therapy using the herpes simplex virus thymidine kinase gene in cell and animal models of human prostate cancer: changes in tumour cell proliferative activity. BJU Int. 85 (2000) 759-766
-
(2000)
BJU Int.
, vol.85
, pp. 759-766
-
-
Cheon, J.1
Kim, H.K.2
Moon, D.G.3
Yoon, D.K.4
Cho, J.H.5
Koh, S.K.6
-
18
-
-
0031267107
-
Chemogene therapy: osteocalcin promoter-based suicide gene therapy in combination with methotrexate in a murine osteosarcoma model
-
Cheon J., Ko S.C., Gardner T.A., Shirakawa T., Gotoh A., Kao C., et al. Chemogene therapy: osteocalcin promoter-based suicide gene therapy in combination with methotrexate in a murine osteosarcoma model. Cancer Gene Ther. 4 (1997) 359-365
-
(1997)
Cancer Gene Ther.
, vol.4
, pp. 359-365
-
-
Cheon, J.1
Ko, S.C.2
Gardner, T.A.3
Shirakawa, T.4
Gotoh, A.5
Kao, C.6
-
19
-
-
0842269770
-
The patterns of relapse in osteosarcoma: the Memorial Sloan-Kettering experience
-
Chi S.N., Conklin L.S., Qin J., Meyers P.A., Huvos A.G., Healey J.H., et al. The patterns of relapse in osteosarcoma: the Memorial Sloan-Kettering experience. Pediatr. Blood Cancer 42 (2004) 46-51
-
(2004)
Pediatr. Blood Cancer
, vol.42
, pp. 46-51
-
-
Chi, S.N.1
Conklin, L.S.2
Qin, J.3
Meyers, P.A.4
Huvos, A.G.5
Healey, J.H.6
-
21
-
-
20044388552
-
Delta24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization
-
Conrad C., Miller C.R., Ji Y., Gomez-Manzano C., Bharara S., McMurray J.S., et al. Delta24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization. Cancer Gene Ther. 12 (2005) 284-294
-
(2005)
Cancer Gene Ther.
, vol.12
, pp. 284-294
-
-
Conrad, C.1
Miller, C.R.2
Ji, Y.3
Gomez-Manzano, C.4
Bharara, S.5
McMurray, J.S.6
-
22
-
-
14444284332
-
Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells
-
Craig C., Kim M., Ohri E., Wersto R., Katayose D., Li Z., et al. Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells. Oncogene 16 (1998) 265-272
-
(1998)
Oncogene
, vol.16
, pp. 265-272
-
-
Craig, C.1
Kim, M.2
Ohri, E.3
Wersto, R.4
Katayose, D.5
Li, Z.6
-
23
-
-
0035300490
-
Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells
-
Cripe T.P., Dunphy E.J., Holub A.D., Saini A., Vasi N.H., Mahller Y.Y., et al. Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells. Cancer Res 61 (2001) 2953-2960
-
(2001)
Cancer Res
, vol.61
, pp. 2953-2960
-
-
Cripe, T.P.1
Dunphy, E.J.2
Holub, A.D.3
Saini, A.4
Vasi, N.H.5
Mahller, Y.Y.6
-
24
-
-
0028875936
-
Transfer of genes to humans: early lessons and obstacles to success
-
Crystal R.G. Transfer of genes to humans: early lessons and obstacles to success. Science 270 (1995) 404-410
-
(1995)
Science
, vol.270
, pp. 404-410
-
-
Crystal, R.G.1
-
25
-
-
0034804767
-
Growth suppression of established human osteosarcoma lung metastases in mice by aerosol gene therapy with PEI-p53 complexes
-
Densmore C.L., Kleinerman E.S., Gautam A., Jia S.F., Xu B., Worth L.L., et al. Growth suppression of established human osteosarcoma lung metastases in mice by aerosol gene therapy with PEI-p53 complexes. Cancer Gene Ther. 8 (2001) 619-627
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 619-627
-
-
Densmore, C.L.1
Kleinerman, E.S.2
Gautam, A.3
Jia, S.F.4
Xu, B.5
Worth, L.L.6
-
26
-
-
0035887153
-
A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy
-
DeWeese T.L., van der Poel H., Li S., Mikhak B., Drew R., Goemann M., et al. A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy. Cancer Res. 61 (2001) 7464-7472
-
(2001)
Cancer Res.
, vol.61
, pp. 7464-7472
-
-
DeWeese, T.L.1
van der Poel, H.2
Li, S.3
Mikhak, B.4
Drew, R.5
Goemann, M.6
-
27
-
-
0036325125
-
Gene therapy for meningioma: improved gene delivery with targeted adenoviruses
-
Dirven C.M., Grill J., Lamfers M.L., Van der Valk P., Leonhart A.M., Van Beusechem V.W., et al. Gene therapy for meningioma: improved gene delivery with targeted adenoviruses. J. Neurosurg. 97 (2002) 441-449
-
(2002)
J. Neurosurg.
, vol.97
, pp. 441-449
-
-
Dirven, C.M.1
Grill, J.2
Lamfers, M.L.3
Van der Valk, P.4
Leonhart, A.M.5
Van Beusechem, V.W.6
-
28
-
-
0033925797
-
Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells
-
Dmitriev I., Kashentseva E., Rogers B.E., Krasnykh V., and Curiel D.T. Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells. J. Virol. 74 (2000) 6875-6884
-
(2000)
J. Virol.
, vol.74
, pp. 6875-6884
-
-
Dmitriev, I.1
Kashentseva, E.2
Rogers, B.E.3
Krasnykh, V.4
Curiel, D.T.5
-
29
-
-
33947131267
-
-
Dorfman, HD, Czemiak, B, Bone tumors. St. Louis: Mosby; 1997.
-
-
-
-
30
-
-
0029907239
-
Targeted gene delivery by tropism-modified adenoviral vectors
-
Douglas J.T., Rogers B.E., Rosenfeld M.E., Michael S.I., Feng M., and Curiel D.T. Targeted gene delivery by tropism-modified adenoviral vectors. Nat. Biotechnol. 14 (1996) 1574-1578
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 1574-1578
-
-
Douglas, J.T.1
Rogers, B.E.2
Rosenfeld, M.E.3
Michael, S.I.4
Feng, M.5
Curiel, D.T.6
-
31
-
-
4444219732
-
Transductional targeting of adenoviral cancer gene therapy
-
Everts M., and Curiel D.T. Transductional targeting of adenoviral cancer gene therapy. Curr. Gene Ther. 4 (2004) 337-346
-
(2004)
Curr. Gene Ther.
, vol.4
, pp. 337-346
-
-
Everts, M.1
Curiel, D.T.2
-
32
-
-
0030883047
-
Long-term follow-up and post-relapse survival in patients with non-metastatic osteosarcoma of the extremity treated with neoadjuvant chemotherapy
-
Ferrari S., Bacci G., Picci P., Mercuri M., Briccoli A., Pinto D., et al. Long-term follow-up and post-relapse survival in patients with non-metastatic osteosarcoma of the extremity treated with neoadjuvant chemotherapy. Ann. Oncol. 8 (1997) 765-771
-
(1997)
Ann. Oncol.
, vol.8
, pp. 765-771
-
-
Ferrari, S.1
Bacci, G.2
Picci, P.3
Mercuri, M.4
Briccoli, A.5
Pinto, D.6
-
33
-
-
9044238439
-
Loss of heterozygosity of the RB gene is a poor prognostic factor in patients with osteosarcoma
-
Feugeas O., Guriec N., Babin-Boilletot A., Marcellin L., Simon P., Babin S., et al. Loss of heterozygosity of the RB gene is a poor prognostic factor in patients with osteosarcoma. J. Clin. Oncol. 14 (1996) 467-472
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 467-472
-
-
Feugeas, O.1
Guriec, N.2
Babin-Boilletot, A.3
Marcellin, L.4
Simon, P.5
Babin, S.6
-
34
-
-
0035755265
-
Gene therapy: some results, many problems to solve
-
Fischer A. Gene therapy: some results, many problems to solve. Cell. Mol. Biol. (Noisy-le-Grand) 47 (2001) 1269-1275
-
(2001)
Cell. Mol. Biol. (Noisy-le-Grand)
, vol.47
, pp. 1269-1275
-
-
Fischer, A.1
-
35
-
-
0028030882
-
MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status
-
Florenes V.A., Maelandsmo G.M., Forus A., Andreassen A., Myklebost O., and Fodstad O. MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status. J. Natl. Cancer Inst. 86 (1994) 1297-1302
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 1297-1302
-
-
Florenes, V.A.1
Maelandsmo, G.M.2
Forus, A.3
Andreassen, A.4
Myklebost, O.5
Fodstad, O.6
-
36
-
-
0037347485
-
Dendritic cells reconstituted with human telomerase gene induce potent cytotoxic T-cell response against different types of tumors
-
Frolkis M., Fischer M.B., Wang Z., Lebkowski J.S., Chiu C.P., and Majumdar A.S. Dendritic cells reconstituted with human telomerase gene induce potent cytotoxic T-cell response against different types of tumors. Cancer Gene Ther. 10 (2003) 239-249
-
(2003)
Cancer Gene Ther.
, vol.10
, pp. 239-249
-
-
Frolkis, M.1
Fischer, M.B.2
Wang, Z.3
Lebkowski, J.S.4
Chiu, C.P.5
Majumdar, A.S.6
-
38
-
-
0034610723
-
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo
-
Fueyo J., Gomez-Manzano C., Alemany R., Lee P.S., McDonnell T.J., Mitlianga P., et al. A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene 19 (2000) 2-12
-
(2000)
Oncogene
, vol.19
, pp. 2-12
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Alemany, R.3
Lee, P.S.4
McDonnell, T.J.5
Mitlianga, P.6
-
39
-
-
0029904706
-
Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity
-
Gallardo D., Drazan K.E., and McBride W.H. Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity. Cancer Res. 56 (1996) 4891-4893
-
(1996)
Cancer Res.
, vol.56
, pp. 4891-4893
-
-
Gallardo, D.1
Drazan, K.E.2
McBride, W.H.3
-
40
-
-
15744395153
-
Adenovirus-mediated p53 gene therapy in osteosarcoma cell lines: sensitization to cisplatin and doxorubicin
-
Ganjavi H., Gee M., Narendran A., Parkinson N., Krishnamoorthy M., Freedman M.H., et al. Adenovirus-mediated p53 gene therapy in osteosarcoma cell lines: sensitization to cisplatin and doxorubicin. Cancer Gene Ther. (2005)
-
(2005)
Cancer Gene Ther.
-
-
Ganjavi, H.1
Gee, M.2
Narendran, A.3
Parkinson, N.4
Krishnamoorthy, M.5
Freedman, M.H.6
-
41
-
-
0036468548
-
Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts
-
Geoerger B., Grill J., Opolon P., Morizet J., Aubert G., Terrier-Lacombe M.J., et al. Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts. Cancer Res. 62 (2002) 764-772
-
(2002)
Cancer Res.
, vol.62
, pp. 764-772
-
-
Geoerger, B.1
Grill, J.2
Opolon, P.3
Morizet, J.4
Aubert, G.5
Terrier-Lacombe, M.J.6
-
42
-
-
4143092788
-
Oncolytic activity of p53-expressing conditionally replicative adenovirus AdDelta24-p53 against human malignant glioma
-
Geoerger B., Vassal G., Opolon P., Dirven C.M., Morizet J., Laudani L., et al. Oncolytic activity of p53-expressing conditionally replicative adenovirus AdDelta24-p53 against human malignant glioma. Cancer Res. 64 (2004) 5753-5759
-
(2004)
Cancer Res.
, vol.64
, pp. 5753-5759
-
-
Geoerger, B.1
Vassal, G.2
Opolon, P.3
Dirven, C.M.4
Morizet, J.5
Laudani, L.6
-
43
-
-
2942528908
-
An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism
-
Glasgow J.N., Kremer E.J., Hemminki A., Siegal G.P., Douglas J.T., and Curiel D.T. An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism. Virology 324 (2004) 103-116
-
(2004)
Virology
, vol.324
, pp. 103-116
-
-
Glasgow, J.N.1
Kremer, E.J.2
Hemminki, A.3
Siegal, G.P.4
Douglas, J.T.5
Curiel, D.T.6
-
44
-
-
20144389514
-
Coxsackievirus and adenovirus receptor expression on primary osteosarcoma specimens and implications for gene therapy with recombinant adenoviruses
-
[author reply 2447-8; 2005]
-
Graat H.C., Wuisman P.I., van Beusechem V.W., Carette J.E., Gerritsen W.R., Bras J., et al. Coxsackievirus and adenovirus receptor expression on primary osteosarcoma specimens and implications for gene therapy with recombinant adenoviruses. Clin. Cancer Res. 11 (2005) 2445-2447 [author reply 2447-8; 2005]
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 2445-2447
-
-
Graat, H.C.1
Wuisman, P.I.2
van Beusechem, V.W.3
Carette, J.E.4
Gerritsen, W.R.5
Bras, J.6
-
45
-
-
33746486078
-
[Gene therapy was declared a success. However, one patient was already dead]
-
Grez M. [Gene therapy was declared a success. However, one patient was already dead]. MMW Fortschr. Med. 148 (2006) 16
-
(2006)
MMW Fortschr. Med.
, vol.148
, pp. 16
-
-
Grez, M.1
-
46
-
-
0034895056
-
Combined targeting of adenoviruses to integrins and epidermal growth factor receptors increases gene transfer into primary glioma cells and spheroids
-
Grill J., Van Beusechem V.W., Van Der Valk P., Dirven C.M., Leonhart A., Pherai D.S., et al. Combined targeting of adenoviruses to integrins and epidermal growth factor receptors increases gene transfer into primary glioma cells and spheroids. Clin. Cancer Res. 7 (2001) 641-650
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 641-650
-
-
Grill, J.1
Van Beusechem, V.W.2
Van Der Valk, P.3
Dirven, C.M.4
Leonhart, A.5
Pherai, D.S.6
-
47
-
-
0032947565
-
Oncogenic transformation-dependent expression of a transcription factor NF-Y subunit
-
Gu Z., Kuntz-Simon G., Rommelaere J., and Cornelis J. Oncogenic transformation-dependent expression of a transcription factor NF-Y subunit. Mol. Carcinog. 24 (1999) 294-299
-
(1999)
Mol. Carcinog.
, vol.24
, pp. 294-299
-
-
Gu, Z.1
Kuntz-Simon, G.2
Rommelaere, J.3
Cornelis, J.4
-
48
-
-
0030252631
-
P53 gene abnormalities in osteosarcoma
-
Guo W., Wang X., and Feng C. P53 gene abnormalities in osteosarcoma. Chin Med. J. (Engl.) 109 (1996) 752-755
-
(1996)
Chin Med. J. (Engl.)
, vol.109
, pp. 752-755
-
-
Guo, W.1
Wang, X.2
Feng, C.3
-
49
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S., von Kalle C., Schmidt M., Le Deist F., Wulffraat N., McIntyre E., et al. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 348 (2003) 255-256
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
von Kalle, C.2
Schmidt, M.3
Le Deist, F.4
Wulffraat, N.5
McIntyre, E.6
-
50
-
-
0033946856
-
Targeting of adenoviral vectors through a bispecific single-chain antibody
-
Haisma H.J., Grill J., Curiel D.T., Hoogeland S., van Beusechem V.W., Pinedo H.M., et al. Targeting of adenoviral vectors through a bispecific single-chain antibody. Cancer Gene Ther. 7 (2000) 901-904
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 901-904
-
-
Haisma, H.J.1
Grill, J.2
Curiel, D.T.3
Hoogeland, S.4
van Beusechem, V.W.5
Pinedo, H.M.6
-
51
-
-
0022402666
-
Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition
-
Hansen M.F., Koufos A., Gallie B.L., Phillips R.A., Fodstad O., Brogger A., et al. Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition. Proc. Natl. Acad Sci. U. S. A. 82 (1985) 6216-6220
-
(1985)
Proc. Natl. Acad Sci. U. S. A.
, vol.82
, pp. 6216-6220
-
-
Hansen, M.F.1
Koufos, A.2
Gallie, B.L.3
Phillips, R.A.4
Fodstad, O.5
Brogger, A.6
-
52
-
-
0030100291
-
Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein
-
Harris M.P., Sutjipto S., Wills K.N., Hancock W., Cornell D., Johnson D.E., et al. Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein. Cancer Gene Ther. 3 (1996) 121-130
-
(1996)
Cancer Gene Ther.
, vol.3
, pp. 121-130
-
-
Harris, M.P.1
Sutjipto, S.2
Wills, K.N.3
Hancock, W.4
Cornell, D.5
Johnson, D.E.6
-
53
-
-
0033589743
-
Cellular immune responses of healthy individuals to intradermal administration of an E1-E3-adenovirus gene transfer vector
-
Harvey B.G., Worgall S., Ely S., Leopold P.L., and Crystal R.G. Cellular immune responses of healthy individuals to intradermal administration of an E1-E3-adenovirus gene transfer vector. Hum. Gene Ther. 10 (1999) 2823-2837
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 2823-2837
-
-
Harvey, B.G.1
Worgall, S.2
Ely, S.3
Leopold, P.L.4
Crystal, R.G.5
-
54
-
-
0035904982
-
Conditional gene targeting for cancer gene therapy
-
Haviv Y.S., and Curiel D.T. Conditional gene targeting for cancer gene therapy. Adv. Drug Delivery Rev. 53 (2001) 135-154
-
(2001)
Adv. Drug Delivery Rev.
, vol.53
, pp. 135-154
-
-
Haviv, Y.S.1
Curiel, D.T.2
-
55
-
-
0033665576
-
Efficacy of a replication-selective adenovirus against ovarian carcinomatosis is dependent on tumor burden, viral replication and p53 status
-
Heise C., Ganly I., Kim Y.T., Sampson-Johannes A., Brown R., and Kirn D. Efficacy of a replication-selective adenovirus against ovarian carcinomatosis is dependent on tumor burden, viral replication and p53 status. Gene Ther. 7 (2000) 1925-1929
-
(2000)
Gene Ther.
, vol.7
, pp. 1925-1929
-
-
Heise, C.1
Ganly, I.2
Kim, Y.T.3
Sampson-Johannes, A.4
Brown, R.5
Kirn, D.6
-
56
-
-
0030917202
-
ONYX-015 an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
-
Heise C., Sampson-Johannes A., Williams A., McCormick F., Von Hoff D.D., and Kirn D.H. ONYX-015 an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat. Med. 3 (1997) 639-645
-
(1997)
Nat. Med.
, vol.3
, pp. 639-645
-
-
Heise, C.1
Sampson-Johannes, A.2
Williams, A.3
McCormick, F.4
Von Hoff, D.D.5
Kirn, D.H.6
-
57
-
-
0033152894
-
Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy
-
Heise C.C., Williams A.M., Xue S., Propst M., and Kirn D.H. Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy. Cancer Res. 59 (1999) 2623-2628
-
(1999)
Cancer Res.
, vol.59
, pp. 2623-2628
-
-
Heise, C.C.1
Williams, A.M.2
Xue, S.3
Propst, M.4
Kirn, D.H.5
-
58
-
-
17544363106
-
Osteosarcoma cell lines display variable individual reactions on wildtype p53 and Rb tumour-suppressor transgenes
-
Hellwinkel O.J., Muller J., Pollmann A., and Kabisch H. Osteosarcoma cell lines display variable individual reactions on wildtype p53 and Rb tumour-suppressor transgenes. J. Gene Med. 7 (2005) 407-419
-
(2005)
J. Gene Med.
, vol.7
, pp. 407-419
-
-
Hellwinkel, O.J.1
Muller, J.2
Pollmann, A.3
Kabisch, H.4
-
59
-
-
0037301795
-
A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model
-
Hemminki A., Kanerva A., Kremer E.J., Bauerschmitz G.J., Smith B.F., Liu B., et al. A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model. Mol. Ther. 7 (2003) 163-173
-
(2003)
Mol. Ther.
, vol.7
, pp. 163-173
-
-
Hemminki, A.1
Kanerva, A.2
Kremer, E.J.3
Bauerschmitz, G.J.4
Smith, B.F.5
Liu, B.6
-
60
-
-
0028283086
-
Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli
-
Henry L.J., Xia D., Wilke M.E., Deisenhofer J., and Gerard R.D. Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli. J. Virol. 68 (1994) 5239-5246
-
(1994)
J. Virol.
, vol.68
, pp. 5239-5246
-
-
Henry, L.J.1
Xia, D.2
Wilke, M.E.3
Deisenhofer, J.4
Gerard, R.D.5
-
61
-
-
0031802635
-
Viral vectors, tools for gene transfer in the nervous system
-
Hermens W.T., and Verhaagen J. Viral vectors, tools for gene transfer in the nervous system. Prog. Neurobiol. 55 (1998) 399-432
-
(1998)
Prog. Neurobiol.
, vol.55
, pp. 399-432
-
-
Hermens, W.T.1
Verhaagen, J.2
-
62
-
-
0027496518
-
In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase
-
Huber B.E., Austin E.A., Good S.S., Knick V.C., Tibbels S., and Richards C.A. In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase. Cancer Res. 53 (1993) 4619-4626
-
(1993)
Cancer Res.
, vol.53
, pp. 4619-4626
-
-
Huber, B.E.1
Austin, E.A.2
Good, S.S.3
Knick, V.C.4
Tibbels, S.5
Richards, C.A.6
-
64
-
-
0036196165
-
Eradication of osteosarcoma lung metastases following intranasal interleukin-12 gene therapy using a nonviral polyethylenimine vector
-
Jia S.F., Worth L.L., Densmore C.L., Xu B., Zhou Z., and Kleinerman E.S. Eradication of osteosarcoma lung metastases following intranasal interleukin-12 gene therapy using a nonviral polyethylenimine vector. Cancer Gene Ther. 9 (2002) 260-266
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 260-266
-
-
Jia, S.F.1
Worth, L.L.2
Densmore, C.L.3
Xu, B.4
Zhou, Z.5
Kleinerman, E.S.6
-
65
-
-
0033504341
-
A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies
-
Jia S.F., Worth L.L., and Kleinerman E.S. A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies. Clin. Exp. Metastasis 17 (1999) 501-506
-
(1999)
Clin. Exp. Metastasis
, vol.17
, pp. 501-506
-
-
Jia, S.F.1
Worth, L.L.2
Kleinerman, E.S.3
-
66
-
-
0031043426
-
In vivo gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by adenovirus-mediated transfer of cytosine deaminase gene
-
Kanai F., Lan K.H., Shiratori Y., Tanaka T., Ohashi M., Okudaira T., et al. In vivo gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by adenovirus-mediated transfer of cytosine deaminase gene. Cancer Res. 57 (1997) 461-465
-
(1997)
Cancer Res.
, vol.57
, pp. 461-465
-
-
Kanai, F.1
Lan, K.H.2
Shiratori, Y.3
Tanaka, T.4
Ohashi, M.5
Okudaira, T.6
-
67
-
-
16644364383
-
Osteosarcoma and chondrosarcoma as targets for virus vectors and herpes simplex virus thymidine kinase/ganciclovir gene therapy
-
Ketola A., Maatta A.M., Pasanen T., Tulimaki K., and Wahlfors J. Osteosarcoma and chondrosarcoma as targets for virus vectors and herpes simplex virus thymidine kinase/ganciclovir gene therapy. Int. J. Mol. Med. 13 (2004) 705-710
-
(2004)
Int. J. Mol. Med.
, vol.13
, pp. 705-710
-
-
Ketola, A.1
Maatta, A.M.2
Pasanen, T.3
Tulimaki, K.4
Wahlfors, J.5
-
68
-
-
0033831080
-
a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri F.R., Nemunaitis J., Ganly I., Arseneau J., Tannock I.F., Romel L., et al. a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat. Med. 6 (2000) 879-885
-
(2000)
Nat. Med.
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
Arseneau, J.4
Tannock, I.F.5
Romel, L.6
-
69
-
-
0034754136
-
Epidermal growth factor receptor biology (IMC-C225)
-
Kim E.S., Khuri F.R., and Herbst R.S. Epidermal growth factor receptor biology (IMC-C225). Curr. Opin Oncol. 13 (2001) 506-513
-
(2001)
Curr. Opin Oncol.
, vol.13
, pp. 506-513
-
-
Kim, E.S.1
Khuri, F.R.2
Herbst, R.S.3
-
70
-
-
33645553503
-
Osteosarcoma: anatomic and histologic variants
-
Klein M.J., and Siegal G.P. Osteosarcoma: anatomic and histologic variants. Am. J. Clin Pathol. 125 (2006) 555-581
-
(2006)
Am. J. Clin Pathol.
, vol.125
, pp. 555-581
-
-
Klein, M.J.1
Siegal, G.P.2
-
71
-
-
0034168328
-
Osteocalcin-directed gene therapy for prostate-cancer bone metastasis
-
Koeneman K.S., Kao C., Ko S.C., Yang L., Wada Y., Kallmes D.F., et al. Osteocalcin-directed gene therapy for prostate-cancer bone metastasis. World J. Urol. 18 (2000) 102-110
-
(2000)
World J. Urol.
, vol.18
, pp. 102-110
-
-
Koeneman, K.S.1
Kao, C.2
Ko, S.C.3
Yang, L.4
Wada, Y.5
Kallmes, D.F.6
-
72
-
-
0032188839
-
Reversal of CPT-11 resistance of lung cancer cells by adenovirus-mediated gene transfer of the human carboxylesterase cDNA
-
Kojima A., Hackett N.R., and Crystal R.G. Reversal of CPT-11 resistance of lung cancer cells by adenovirus-mediated gene transfer of the human carboxylesterase cDNA. Cancer Res. 58 (1998) 4368-4374
-
(1998)
Cancer Res.
, vol.58
, pp. 4368-4374
-
-
Kojima, A.1
Hackett, N.R.2
Crystal, R.G.3
-
73
-
-
0031913203
-
Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob
-
Krasnykh V., Dmitriev I., Mikheeva G., Miller C.R., Belousova N., and Curiel D.T. Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob. J. Virol. 72 (1998) 1844-1852
-
(1998)
J. Virol.
, vol.72
, pp. 1844-1852
-
-
Krasnykh, V.1
Dmitriev, I.2
Mikheeva, G.3
Miller, C.R.4
Belousova, N.5
Curiel, D.T.6
-
74
-
-
6344285229
-
Atomic force microscopy imaging of retroviruses: human immunodeficiency virus and murine leukemia virus
-
Kuznetsov Y.G., Victoria J.G., Low A., Robinson Jr. W.E., Fan H., and McPherson A. Atomic force microscopy imaging of retroviruses: human immunodeficiency virus and murine leukemia virus. Scanning 26 (2004) 209-216
-
(2004)
Scanning
, vol.26
, pp. 209-216
-
-
Kuznetsov, Y.G.1
Victoria, J.G.2
Low, A.3
Robinson Jr., W.E.4
Fan, H.5
McPherson, A.6
-
75
-
-
0242300211
-
Atomic force microscopy investigation of human immunodeficiency virus (HIV) and HIV-infected lymphocytes
-
Kuznetsov Y.G., Victoria J.G., Robinson Jr. W.E., and McPherson A. Atomic force microscopy investigation of human immunodeficiency virus (HIV) and HIV-infected lymphocytes. J. Virol. 77 (2003) 11896-11909
-
(2003)
J. Virol.
, vol.77
, pp. 11896-11909
-
-
Kuznetsov, Y.G.1
Victoria, J.G.2
Robinson Jr., W.E.3
McPherson, A.4
-
76
-
-
0035872424
-
Interleukin (IL)-12 and IL-12 gene transfer up-regulate Fas expression in human osteosarcoma and breast cancer cells
-
Lafleur E.A., Jia S.F., Worth L.L., Zhou Z., Owen-Schaub L.B., and Kleinerman E.S. Interleukin (IL)-12 and IL-12 gene transfer up-regulate Fas expression in human osteosarcoma and breast cancer cells. Cancer Res. 61 (2001) 4066-4071
-
(2001)
Cancer Res.
, vol.61
, pp. 4066-4071
-
-
Lafleur, E.A.1
Jia, S.F.2
Worth, L.L.3
Zhou, Z.4
Owen-Schaub, L.B.5
Kleinerman, E.S.6
-
77
-
-
27144450892
-
Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma
-
Lamfers M.L., Gianni D., Tung C.H., Idema S., Schagen F.H., Carette J.E., et al. Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma. Cancer Res. 65 (2005) 9398-9405
-
(2005)
Cancer Res.
, vol.65
, pp. 9398-9405
-
-
Lamfers, M.L.1
Gianni, D.2
Tung, C.H.3
Idema, S.4
Schagen, F.H.5
Carette, J.E.6
-
78
-
-
0037109013
-
Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy
-
Lamfers M.L., Grill J., Dirven C.M., Van Beusechem V.W., Geoerger B., Van Den Berg J., et al. Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy. Cancer Res. 62 (2002) 5736-5742
-
(2002)
Cancer Res.
, vol.62
, pp. 5736-5742
-
-
Lamfers, M.L.1
Grill, J.2
Dirven, C.M.3
Van Beusechem, V.W.4
Geoerger, B.5
Van Den Berg, J.6
-
79
-
-
0033835016
-
A prospective phase II trial of ONYX-015 adenovirus and chemotherapy in recurrent squamous cell carcinoma of the head and neck (the Baylor experience)
-
Lamont J.P., Nemunaitis J., Kuhn J.A., Landers S.A., and McCarty T.M. A prospective phase II trial of ONYX-015 adenovirus and chemotherapy in recurrent squamous cell carcinoma of the head and neck (the Baylor experience). Ann. Surg. Oncol. 7 (2000) 588-592
-
(2000)
Ann. Surg. Oncol.
, vol.7
, pp. 588-592
-
-
Lamont, J.P.1
Nemunaitis, J.2
Kuhn, J.A.3
Landers, S.A.4
McCarty, T.M.5
-
80
-
-
33644627889
-
The expanding role of aerosols in systemic drug delivery, gene therapy, and vaccination
-
Laube B.L. The expanding role of aerosols in systemic drug delivery, gene therapy, and vaccination. Respir. Care 50 (2005) 1161-1176
-
(2005)
Respir. Care
, vol.50
, pp. 1161-1176
-
-
Laube, B.L.1
-
81
-
-
28044459199
-
Fluorescently tagged canine adenovirus via modification with protein IX-enhanced green fluorescent protein
-
Le L.P., Li J., Ternovoi V.V., Siegal G.P., and Curiel D.T. Fluorescently tagged canine adenovirus via modification with protein IX-enhanced green fluorescent protein. J. Gen. Virol. 86 (2005) 3201-3208
-
(2005)
J. Gen. Virol.
, vol.86
, pp. 3201-3208
-
-
Le, L.P.1
Li, J.2
Ternovoi, V.V.3
Siegal, G.P.4
Curiel, D.T.5
-
82
-
-
33645140225
-
Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells
-
Le L.P., Rivera A.A., Glasgow J.N., Ternovoi V.V., Wu H., Wang M., et al. Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells. Gene Ther. 13 (2006) 389-399
-
(2006)
Gene Ther.
, vol.13
, pp. 389-399
-
-
Le, L.P.1
Rivera, A.A.2
Glasgow, J.N.3
Ternovoi, V.V.4
Wu, H.5
Wang, M.6
-
83
-
-
0023715595
-
A cancer family syndrome in twenty-four kindreds
-
Li F.P., Fraumeni Jr. J.F., Mulvihill J.J., Blattner W.A., Dreyfus M.G., Tucker M.A., et al. A cancer family syndrome in twenty-four kindreds. Cancer Res. 48 (1988) 5358-5362
-
(1988)
Cancer Res.
, vol.48
, pp. 5358-5362
-
-
Li, F.P.1
Fraumeni Jr., J.F.2
Mulvihill, J.J.3
Blattner, W.A.4
Dreyfus, M.G.5
Tucker, M.A.6
-
84
-
-
33745280584
-
Anti-tumor efficacy of a transcriptional replication-competent adenovirus, Ad-OC-E1a, for osteosarcoma pulmonary metastasis
-
Li X., Jung C., Liu Y.H., Bae K.H., Zhang Y.P., Zhang H.J., et al. Anti-tumor efficacy of a transcriptional replication-competent adenovirus, Ad-OC-E1a, for osteosarcoma pulmonary metastasis. J. Gene Med. 8 (2006) 679-689
-
(2006)
J. Gene Med.
, vol.8
, pp. 679-689
-
-
Li, X.1
Jung, C.2
Liu, Y.H.3
Bae, K.H.4
Zhang, Y.P.5
Zhang, H.J.6
-
85
-
-
0033556093
-
Loss of adenoviral receptor expression in human bladder cancer cells: a potential impact on the efficacy of gene therapy
-
Li Y., Pong R.C., Bergelson J.M., Hall M.C., Sagalowsky A.I., Tseng C.P., et al. Loss of adenoviral receptor expression in human bladder cancer cells: a potential impact on the efficacy of gene therapy. Cancer Res. 59 (1999) 325-330
-
(1999)
Cancer Res.
, vol.59
, pp. 325-330
-
-
Li, Y.1
Pong, R.C.2
Bergelson, J.M.3
Hall, M.C.4
Sagalowsky, A.I.5
Tseng, C.P.6
-
86
-
-
0035417931
-
A hepatocellular carcinoma-specific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin
-
Li Y., Yu D.C., Chen Y., Amin P., Zhang H., Nguyen N., et al. A hepatocellular carcinoma-specific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin. Cancer Res. 61 (2001) 6428-6436
-
(2001)
Cancer Res.
, vol.61
, pp. 6428-6436
-
-
Li, Y.1
Yu, D.C.2
Chen, Y.3
Amin, P.4
Zhang, H.5
Nguyen, N.6
-
87
-
-
0346780705
-
Interleukin-12 and interleukin-18 change ICAM-I expression, and enhance natural killer cell mediated cytolysis of human osteosarcoma cells
-
Liebau C., Merk H., Schmidt S., Roesel C., Karreman C., Prisack J.B., et al. Interleukin-12 and interleukin-18 change ICAM-I expression, and enhance natural killer cell mediated cytolysis of human osteosarcoma cells. Cytokines Cell Mol. Ther. 7 (2002) 135-142
-
(2002)
Cytokines Cell Mol. Ther.
, vol.7
, pp. 135-142
-
-
Liebau, C.1
Merk, H.2
Schmidt, S.3
Roesel, C.4
Karreman, C.5
Prisack, J.B.6
-
88
-
-
6444226708
-
Immunotherapy by gene transfer with plasmids encoding IL-12/IL-18 is superior to IL-23/IL-18 gene transfer in a rat osteosarcoma model
-
Liebau C., Roesel C., Schmidt S., Karreman C., Prisack J.B., Bojar H., et al. Immunotherapy by gene transfer with plasmids encoding IL-12/IL-18 is superior to IL-23/IL-18 gene transfer in a rat osteosarcoma model. Anticancer Res. 24 (2004) 2861-2867
-
(2004)
Anticancer Res.
, vol.24
, pp. 2861-2867
-
-
Liebau, C.1
Roesel, C.2
Schmidt, S.3
Karreman, C.4
Prisack, J.B.5
Bojar, H.6
-
89
-
-
0032953566
-
Limb salvage and outcome of osteosarcoma. The University of Muenster experience
-
Lindner N.J., Ramm O., Hillmann A., Roedl R., Gosheger G., Brinkschmidt C., et al. Limb salvage and outcome of osteosarcoma. The University of Muenster experience. Clin. Orthop. (1999) 83-89
-
(1999)
Clin. Orthop.
, pp. 83-89
-
-
Lindner, N.J.1
Ramm, O.2
Hillmann, A.3
Roedl, R.4
Gosheger, G.5
Brinkschmidt, C.6
-
90
-
-
0026326203
-
Adjuvant chemotherapy of high-grade osteosarcoma of the extremity. Updated results of the Multi-Institutional Osteosarcoma Study
-
Link M.P., Goorin A.M., Horowitz M., Meyer W.H., Belasco J., Baker A., et al. Adjuvant chemotherapy of high-grade osteosarcoma of the extremity. Updated results of the Multi-Institutional Osteosarcoma Study. Clin. Orthop. (1991) 8-14
-
(1991)
Clin. Orthop.
, pp. 8-14
-
-
Link, M.P.1
Goorin, A.M.2
Horowitz, M.3
Meyer, W.H.4
Belasco, J.5
Baker, A.6
-
91
-
-
0030964879
-
p53 and MDM2 alterations in osteosarcomas: correlation with clinicopathologic features and proliferative rate
-
Lonardo F., Ueda T., Huvos A.G., Healey J., and Ladanyi M. p53 and MDM2 alterations in osteosarcomas: correlation with clinicopathologic features and proliferative rate. Cancer 79 (1997) 1541-1547
-
(1997)
Cancer
, vol.79
, pp. 1541-1547
-
-
Lonardo, F.1
Ueda, T.2
Huvos, A.G.3
Healey, J.4
Ladanyi, M.5
-
92
-
-
0037333336
-
Latest development in viral vectors for gene therapy
-
Lundstrom K. Latest development in viral vectors for gene therapy. Trends Biotechnol. 21 (2003) 117-122
-
(2003)
Trends Biotechnol.
, vol.21
, pp. 117-122
-
-
Lundstrom, K.1
-
93
-
-
0026332609
-
Osteoid osteoma. Diagnosis, localization, and treatment
-
Marcove R.C., Heelan R.T., Huvos A.G., Healey J., and Lindeque B.G. Osteoid osteoma. Diagnosis, localization, and treatment. Clin. Orthop. (1991) 197-201
-
(1991)
Clin. Orthop.
, pp. 197-201
-
-
Marcove, R.C.1
Heelan, R.T.2
Huvos, A.G.3
Healey, J.4
Lindeque, B.G.5
-
94
-
-
0023576046
-
Rearrangement of the p53 gene in human osteogenic sarcomas
-
Masuda H., Miller C., Koeffler H.P., Battifora H., and Cline M.J. Rearrangement of the p53 gene in human osteogenic sarcomas. Proc. Natl. Acad Sci. U. S. A. 84 (1987) 7716-7719
-
(1987)
Proc. Natl. Acad Sci. U. S. A.
, vol.84
, pp. 7716-7719
-
-
Masuda, H.1
Miller, C.2
Koeffler, H.P.3
Battifora, H.4
Cline, M.J.5
-
95
-
-
0035881263
-
A conditional replication-competent adenoviral vector, Ad-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis
-
Matsubara S., Wada Y., Gardner T.A., Egawa M., Park M.S., Hsieh C.L., et al. A conditional replication-competent adenoviral vector, Ad-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis. Cancer Res. 61 (2001) 6012-6019
-
(2001)
Cancer Res.
, vol.61
, pp. 6012-6019
-
-
Matsubara, S.1
Wada, Y.2
Gardner, T.A.3
Egawa, M.4
Park, M.S.5
Hsieh, C.L.6
-
96
-
-
0032772690
-
Adenovirus-mediated gene therapy of osteoblasts in vitro and in vivo
-
Mehrara B.J., Saadeh P.B., Steinbrech D.S., Dudziak M., Spector J.A., Greenwald J.A., et al. Adenovirus-mediated gene therapy of osteoblasts in vitro and in vivo. J. Bone Miner. Res. 14 (1999) 1290-1301
-
(1999)
J. Bone Miner. Res.
, vol.14
, pp. 1290-1301
-
-
Mehrara, B.J.1
Saadeh, P.B.2
Steinbrech, D.S.3
Dudziak, M.4
Spector, J.A.5
Greenwald, J.A.6
-
97
-
-
0031861214
-
Intensification of preoperative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol
-
Meyers P.A., Gorlick R., Heller G., Casper E., Lane J., Huvos A.G., et al. Intensification of preoperative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol. J. Clin. Oncol. 16 (1998) 2452-2458
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 2452-2458
-
-
Meyers, P.A.1
Gorlick, R.2
Heller, G.3
Casper, E.4
Lane, J.5
Huvos, A.G.6
-
98
-
-
0025665155
-
Frequency and structure of p53 rearrangements in human osteosarcoma
-
Miller C.W., Aslo A., Tsay C., Slamon D., Ishizaki K., Toguchida J., et al. Frequency and structure of p53 rearrangements in human osteosarcoma. Cancer Res. 50 (1990) 7950-7954
-
(1990)
Cancer Res.
, vol.50
, pp. 7950-7954
-
-
Miller, C.W.1
Aslo, A.2
Tsay, C.3
Slamon, D.4
Ishizaki, K.5
Toguchida, J.6
-
99
-
-
0029791852
-
Alterations of the p53, Rb and MDM2 genes in osteosarcoma
-
Miller C.W., Aslo A., Won A., Tan M., Lampkin B., and Koeffler H.P. Alterations of the p53, Rb and MDM2 genes in osteosarcoma. J. Cancer Res. Clin. Oncol. 122 (1996) 559-565
-
(1996)
J. Cancer Res. Clin. Oncol.
, vol.122
, pp. 559-565
-
-
Miller, C.W.1
Aslo, A.2
Won, A.3
Tan, M.4
Lampkin, B.5
Koeffler, H.P.6
-
100
-
-
33645736049
-
Osteosarcoma: current status of immunotherapy and future trends (Review)
-
Mori K., Redini F., Gouin F., Cherrier B., and Heymann D. Osteosarcoma: current status of immunotherapy and future trends (Review). Oncol. Rep. 15 (2006) 693-700
-
(2006)
Oncol. Rep.
, vol.15
, pp. 693-700
-
-
Mori, K.1
Redini, F.2
Gouin, F.3
Cherrier, B.4
Heymann, D.5
-
101
-
-
0028297316
-
Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor
-
Mullen C.A., Coale M.M., Lowe R., and Blaese R.M. Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor. Cancer Res. 54 (1994) 1503-1506
-
(1994)
Cancer Res.
, vol.54
, pp. 1503-1506
-
-
Mullen, C.A.1
Coale, M.M.2
Lowe, R.3
Blaese, R.M.4
-
102
-
-
18044379986
-
p53 gene therapy of human osteosarcoma using a transferrin-modified cationic liposome
-
Nakase M., Inui M., Okumura K., Kamei T., Nakamura S., and Tagawa T. p53 gene therapy of human osteosarcoma using a transferrin-modified cationic liposome. Mol. Cancer Ther. 4 (2005) 625-631
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 625-631
-
-
Nakase, M.1
Inui, M.2
Okumura, K.3
Kamei, T.4
Nakamura, S.5
Tagawa, T.6
-
103
-
-
0035863458
-
Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
-
Nemunaitis J., Khuri F., Ganly I., Arseneau J., Posner M., Vokes E., et al. Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer. J. Clin. Oncol. 19 (2001) 289-298
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 289-298
-
-
Nemunaitis, J.1
Khuri, F.2
Ganly, I.3
Arseneau, J.4
Posner, M.5
Vokes, E.6
-
104
-
-
0037345749
-
Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer
-
Nencioni A., Muller M.R., Grunebach F., Garuti A., Mingari M.C., Patrone F., et al. Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer. Cancer Gene Ther. 10 (2003) 209-214
-
(2003)
Cancer Gene Ther.
, vol.10
, pp. 209-214
-
-
Nencioni, A.1
Muller, M.R.2
Grunebach, F.3
Garuti, A.4
Mingari, M.C.5
Patrone, F.6
-
105
-
-
0037102156
-
Novel oncolytic adenoviruses targeted to melanoma: specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter
-
Nettelbeck D.M., Rivera A.A., Balague C., Alemany R., and Curiel D.T. Novel oncolytic adenoviruses targeted to melanoma: specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter. Cancer Res. 62 (2002) 4663-4670
-
(2002)
Cancer Res.
, vol.62
, pp. 4663-4670
-
-
Nettelbeck, D.M.1
Rivera, A.A.2
Balague, C.3
Alemany, R.4
Curiel, D.T.5
-
106
-
-
0031084922
-
Efficacy of p53 adenovirus-mediated gene therapy against human breast cancer xenografts
-
Nielsen L.L., Dell J., Maxwell E., Armstrong L., Maneval D., and Catino J.J. Efficacy of p53 adenovirus-mediated gene therapy against human breast cancer xenografts. Cancer Gene Ther. 4 (1997) 129-138
-
(1997)
Cancer Gene Ther.
, vol.4
, pp. 129-138
-
-
Nielsen, L.L.1
Dell, J.2
Maxwell, E.3
Armstrong, L.4
Maneval, D.5
Catino, J.J.6
-
107
-
-
0031608678
-
P53 tumor suppressor gene therapy for cancer
-
Nielsen L.L., and Maneval D.C. P53 tumor suppressor gene therapy for cancer. Cancer Gene Ther. 5 (1998) 52-63
-
(1998)
Cancer Gene Ther.
, vol.5
, pp. 52-63
-
-
Nielsen, L.L.1
Maneval, D.C.2
-
108
-
-
0029743164
-
Regional delivery of an adenovirus vector containing the Escherichia coli cytosine deaminase gene to provide local activation of 5-fluorocytosine to suppress the growth of colon carcinoma metastatic to liver
-
Ohwada A., Hirschowitz E.A., and Crystal R.G. Regional delivery of an adenovirus vector containing the Escherichia coli cytosine deaminase gene to provide local activation of 5-fluorocytosine to suppress the growth of colon carcinoma metastatic to liver. Hum. Gene Ther. 7 (1996) 1567-1576
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1567-1576
-
-
Ohwada, A.1
Hirschowitz, E.A.2
Crystal, R.G.3
-
109
-
-
20444397790
-
Promoter-controlled infectivity-enhanced conditionally replicative adenoviral vectors for the treatment of gastric cancer
-
Ono H.A., Davydova J.G., Adachi Y., Takayama K., Barker S.D., Reynolds P.N., et al. Promoter-controlled infectivity-enhanced conditionally replicative adenoviral vectors for the treatment of gastric cancer. J. Gastroenterol. 40 (2005) 31-42
-
(2005)
J. Gastroenterol.
, vol.40
, pp. 31-42
-
-
Ono, H.A.1
Davydova, J.G.2
Adachi, Y.3
Takayama, K.4
Barker, S.D.5
Reynolds, P.N.6
-
110
-
-
0037048309
-
Secreted and tumour targeted human carboxylesterase for activation of irinotecan
-
Oosterhoff D., Pinedo H.M., van der Meulen I.H., de Graaf M., Sone T., Kruyt F.A., et al. Secreted and tumour targeted human carboxylesterase for activation of irinotecan. Br. J. Cancer 87 (2002) 659-664
-
(2002)
Br. J. Cancer
, vol.87
, pp. 659-664
-
-
Oosterhoff, D.1
Pinedo, H.M.2
van der Meulen, I.H.3
de Graaf, M.4
Sone, T.5
Kruyt, F.A.6
-
111
-
-
21344445274
-
Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdDelta24
-
Oosterhoff D., Pinedo H.M., Witlox M.A., Carette J.E., Gerritsen W.R., and van Beusechem V.W. Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdDelta24. Gene Ther. 12 (2005) 1011-1018
-
(2005)
Gene Ther.
, vol.12
, pp. 1011-1018
-
-
Oosterhoff, D.1
Pinedo, H.M.2
Witlox, M.A.3
Carette, J.E.4
Gerritsen, W.R.5
van Beusechem, V.W.6
-
112
-
-
2942679889
-
Gene-directed enzyme prodrug therapy for osteosarcoma: sensitization to CPT-11 in vitro and in vivo by adenoviral delivery of a gene encoding secreted carboxylesterase-2
-
Oosterhoff D., Witlox M.A., van Beusechem V.W., Haisma H.J., Schaap G.R., Bras J., et al. Gene-directed enzyme prodrug therapy for osteosarcoma: sensitization to CPT-11 in vitro and in vivo by adenoviral delivery of a gene encoding secreted carboxylesterase-2. Mol. Cancer Ther. 2 (2003) 765-771
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 765-771
-
-
Oosterhoff, D.1
Witlox, M.A.2
van Beusechem, V.W.3
Haisma, H.J.4
Schaap, G.R.5
Bras, J.6
-
113
-
-
19444375104
-
DNA-based therapeutics and DNA delivery systems: a comprehensive review
-
Patil S.D., Rhodes D.G., and Burgess D.J. DNA-based therapeutics and DNA delivery systems: a comprehensive review. AAPS J. 7 (2005) E61-E77
-
(2005)
AAPS J.
, vol.7
-
-
Patil, S.D.1
Rhodes, D.G.2
Burgess, D.J.3
-
114
-
-
0031953510
-
Intercellular delivery of functional p53 by the herpesvirus protein VP22
-
Phelan A., Elliott G., and O'Hare P. Intercellular delivery of functional p53 by the herpesvirus protein VP22. Nat. Biotechnol. 16 (1998) 440-443
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 440-443
-
-
Phelan, A.1
Elliott, G.2
O'Hare, P.3
-
115
-
-
16644391122
-
Limited specificity of promoter constructs for gene therapy in osteosarcoma
-
Pollmann A., Kabisch H., Block A., Muller J., and Hellwinkel O.J. Limited specificity of promoter constructs for gene therapy in osteosarcoma. Int. J. Mol. Med. 14 (2004) 737-742
-
(2004)
Int. J. Mol. Med.
, vol.14
, pp. 737-742
-
-
Pollmann, A.1
Kabisch, H.2
Block, A.3
Muller, J.4
Hellwinkel, O.J.5
-
116
-
-
0036078735
-
ONYX-015, an E1B gene-defective adenovirus, induces cell death in human anaplastic thyroid carcinoma cell lines
-
Portella G., Scala S., Vitagliano D., Vecchio G., and Fusco A. ONYX-015, an E1B gene-defective adenovirus, induces cell death in human anaplastic thyroid carcinoma cell lines. J. Clin. Endocrinol. Metab. 87 (2002) 2525-2531
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 2525-2531
-
-
Portella, G.1
Scala, S.2
Vitagliano, D.3
Vecchio, G.4
Fusco, A.5
-
117
-
-
0034694011
-
A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
-
Rainov N.G. A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum. Gene Ther. 11 (2000) 2389-2401
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 2389-2401
-
-
Rainov, N.G.1
-
118
-
-
29344438820
-
Osteoclasts direct bystander killing of cancer cells in vitro
-
Ramnaraine M., Pan W., and Clohisy D.R. Osteoclasts direct bystander killing of cancer cells in vitro. Bone 38 (2006) 4-12
-
(2006)
Bone
, vol.38
, pp. 4-12
-
-
Ramnaraine, M.1
Pan, W.2
Clohisy, D.R.3
-
119
-
-
0142188699
-
Direct and bystander killing of sarcomas by novel cytosine deaminase fusion gene
-
Ramnaraine M., Pan W., Goblirsch M., Lynch C., Lewis V., Orchard P., et al. Direct and bystander killing of sarcomas by novel cytosine deaminase fusion gene. Cancer Res. 63 (2003) 6847-6854
-
(2003)
Cancer Res.
, vol.63
, pp. 6847-6854
-
-
Ramnaraine, M.1
Pan, W.2
Goblirsch, M.3
Lynch, C.4
Lewis, V.5
Orchard, P.6
-
120
-
-
0031755915
-
Basic fibroblast growth factor enhancement of adenovirus-mediated delivery of the herpes simplex virus thymidine kinase gene results in augmented therapeutic benefit in a murine model of ovarian cancer
-
Rancourt C., Rogers B.E., Sosnowski B.A., Wang M., Piche A., Pierce G.F., et al. Basic fibroblast growth factor enhancement of adenovirus-mediated delivery of the herpes simplex virus thymidine kinase gene results in augmented therapeutic benefit in a murine model of ovarian cancer. Clin. Cancer Res. 4 (1998) 2455-2461
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 2455-2461
-
-
Rancourt, C.1
Rogers, B.E.2
Sosnowski, B.A.3
Wang, M.4
Piche, A.5
Pierce, G.F.6
-
121
-
-
0035177690
-
Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial
-
Reid T., Galanis E., Abbruzzese J., Sze D., Andrews J., Romel L., et al. Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial. Gene Ther. 8 (2001) 1618-1626
-
(2001)
Gene Ther.
, vol.8
, pp. 1618-1626
-
-
Reid, T.1
Galanis, E.2
Abbruzzese, J.3
Sze, D.4
Andrews, J.5
Romel, L.6
-
122
-
-
0036904741
-
Intravascular adenoviral agents in cancer patients: lessons from clinical trials
-
Reid T., Warren R., and Kirn D. Intravascular adenoviral agents in cancer patients: lessons from clinical trials. Cancer Gene Ther. 9 (2002) 979-986
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 979-986
-
-
Reid, T.1
Warren, R.2
Kirn, D.3
-
123
-
-
0032728356
-
Osteosarcoma: oncologic and functional results. A single institutional report covering 22 years
-
Renard A.J., Veth R.P., Schreuder H.W., Pruszczynski M., Bokkerink J.P., van Hoesel Q.G., et al. Osteosarcoma: oncologic and functional results. A single institutional report covering 22 years. J. Surg. Oncol. 72 (1999) 124-129
-
(1999)
J. Surg. Oncol.
, vol.72
, pp. 124-129
-
-
Renard, A.J.1
Veth, R.P.2
Schreuder, H.W.3
Pruszczynski, M.4
Bokkerink, J.P.5
van Hoesel, Q.G.6
-
124
-
-
0030790684
-
Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells
-
Rodriguez R., Schuur E.R., Lim H.Y., Henderson G.A., Simons J.W., and Henderson D.R. Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res. 57 (1997) 2559-2563
-
(1997)
Cancer Res.
, vol.57
, pp. 2559-2563
-
-
Rodriguez, R.1
Schuur, E.R.2
Lim, H.Y.3
Henderson, G.A.4
Simons, J.W.5
Henderson, D.R.6
-
125
-
-
0029564603
-
Adenoviral-mediated delivery of the herpes simplex virus thymidine kinase gene selectively sensitizes human ovarian carcinoma cells to ganciclovir
-
Rosenfeld M.E., Feng M., Michael S.I., Siegal G.P., Alvarez R.D., and Curiel D.T. Adenoviral-mediated delivery of the herpes simplex virus thymidine kinase gene selectively sensitizes human ovarian carcinoma cells to ganciclovir. Clin. Cancer Res. 1 (1995) 1571-1580
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 1571-1580
-
-
Rosenfeld, M.E.1
Feng, M.2
Michael, S.I.3
Siegal, G.P.4
Alvarez, R.D.5
Curiel, D.T.6
-
126
-
-
0031025998
-
Gene therapy for cancer: what have we done and where are we going?
-
Roth J.A., and Cristiano R.J. Gene therapy for cancer: what have we done and where are we going?. J. Natl. Cancer Inst. 89 (1997) 21-39
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 21-39
-
-
Roth, J.A.1
Cristiano, R.J.2
-
127
-
-
51249195723
-
Ueber katarakt in verbindiung mit einer eigentuemlichen haut degeneration
-
Rothmund A. Ueber katarakt in verbindiung mit einer eigentuemlichen haut degeneration. Arch. f. Ophth. 14 (1868) 159-182
-
(1868)
Arch. f. Ophth.
, vol.14
, pp. 159-182
-
-
Rothmund, A.1
-
128
-
-
4644342289
-
Telomerase expression predicts unfavorable outcome in osteosarcoma
-
Sanders R.P., Drissi R., Billups C.A., Daw N.C., Valentine M.B., and Dome J.S. Telomerase expression predicts unfavorable outcome in osteosarcoma. J. Clin Oncol. 22 (2004) 3790-3797
-
(2004)
J. Clin Oncol.
, vol.22
, pp. 3790-3797
-
-
Sanders, R.P.1
Drissi, R.2
Billups, C.A.3
Daw, N.C.4
Valentine, M.B.5
Dome, J.S.6
-
129
-
-
0031800635
-
The mammalian carboxylesterases: from molecules to functions
-
Satoh T., and Hosokawa M. The mammalian carboxylesterases: from molecules to functions. Annu. Rev. Pharmacol. Toxicol. 38 (1998) 257-288
-
(1998)
Annu. Rev. Pharmacol. Toxicol.
, vol.38
, pp. 257-288
-
-
Satoh, T.1
Hosokawa, M.2
-
130
-
-
24144480780
-
Vector-mediated cancer gene therapy: an overview
-
Seth P. Vector-mediated cancer gene therapy: an overview. Cancer Biol. Ther. 4 (2005) 512-517
-
(2005)
Cancer Biol. Ther.
, vol.4
, pp. 512-517
-
-
Seth, P.1
-
131
-
-
0032151946
-
In vivo suppression of osteosarcoma pulmonary metastasis with intravenous osteocalcin promoter-based toxic gene therapy
-
Shirakawa T., Ko S.C., Gardner T.A., Cheon J., Miyamoto T., Gotoh A., et al. In vivo suppression of osteosarcoma pulmonary metastasis with intravenous osteocalcin promoter-based toxic gene therapy. Cancer Gene Ther. 5 (1998) 274-280
-
(1998)
Cancer Gene Ther.
, vol.5
, pp. 274-280
-
-
Shirakawa, T.1
Ko, S.C.2
Gardner, T.A.3
Cheon, J.4
Miyamoto, T.5
Gotoh, A.6
-
132
-
-
0029730701
-
Transcriptional targeting of recombinant adenoviruses to human and murine melanoma cells
-
Siders W.M., Halloran P.J., and Fenton R.G. Transcriptional targeting of recombinant adenoviruses to human and murine melanoma cells. Cancer Res. 56 (1996) 5638-5646
-
(1996)
Cancer Res.
, vol.56
, pp. 5638-5646
-
-
Siders, W.M.1
Halloran, P.J.2
Fenton, R.G.3
-
133
-
-
0032924725
-
Local and systemic control after ablative and limb sparing surgery in patients with osteosarcoma
-
Sluga M., Windhager R., Lang S., Heinzl H., Bielack S., and Kotz R. Local and systemic control after ablative and limb sparing surgery in patients with osteosarcoma. Clin. Orthop. (1999) 120-127
-
(1999)
Clin. Orthop.
, pp. 120-127
-
-
Sluga, M.1
Windhager, R.2
Lang, S.3
Heinzl, H.4
Bielack, S.5
Kotz, R.6
-
134
-
-
0035977949
-
Combination treatment for osteosarcoma with baculoviral vector mediated gene therapy (p53) and chemotherapy (adriamycin)
-
Song S.U., and Boyce F.M. Combination treatment for osteosarcoma with baculoviral vector mediated gene therapy (p53) and chemotherapy (adriamycin). Exp. Mol. Med. 33 (2001) 46-53
-
(2001)
Exp. Mol. Med.
, vol.33
, pp. 46-53
-
-
Song, S.U.1
Boyce, F.M.2
-
135
-
-
17044398835
-
Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma
-
Stefani A.L., Barzon L., Castagliuolo I., Guido M., Pacenti M., Parolin C., et al. Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma. J. Hepatol. 42 (2005) 728-735
-
(2005)
J. Hepatol.
, vol.42
, pp. 728-735
-
-
Stefani, A.L.1
Barzon, L.2
Castagliuolo, I.3
Guido, M.4
Pacenti, M.5
Parolin, C.6
-
136
-
-
27944453541
-
A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy
-
Stoff-Khalili M.A., Rivera A.A., Glasgow J.N., Le L.P., Stoff A., Everts M., et al. A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy. Gene Ther. 12 (2005) 1696-1706
-
(2005)
Gene Ther.
, vol.12
, pp. 1696-1706
-
-
Stoff-Khalili, M.A.1
Rivera, A.A.2
Glasgow, J.N.3
Le, L.P.4
Stoff, A.5
Everts, M.6
-
137
-
-
6944255232
-
Late relapse of osteosarcoma: implications for follow-up and screening
-
Strauss S.J., McTiernan A., and Whelan J.S. Late relapse of osteosarcoma: implications for follow-up and screening. Pediatr. Blood Cancer 43 (2004) 692-697
-
(2004)
Pediatr. Blood Cancer
, vol.43
, pp. 692-697
-
-
Strauss, S.J.1
McTiernan, A.2
Whelan, J.S.3
-
138
-
-
11144238681
-
Productive replication of human adenovirus type 5 in canine cells
-
Ternovoi V.V., Le L.P., Belousova N., Smith B.F., Siegal G.P., and Curiel D.T. Productive replication of human adenovirus type 5 in canine cells. J. Virol. 79 (2005) 1308-1311
-
(2005)
J. Virol.
, vol.79
, pp. 1308-1311
-
-
Ternovoi, V.V.1
Le, L.P.2
Belousova, N.3
Smith, B.F.4
Siegal, G.P.5
Curiel, D.T.6
-
139
-
-
0001743196
-
A hitherto undescribed familial disease
-
Thomson M. A hitherto undescribed familial disease. Br. J. Dermatol. 135 (1923)
-
(1923)
Br. J. Dermatol.
, vol.135
-
-
Thomson, M.1
-
140
-
-
0034073148
-
Sensitization and caffeine potentiation of cisplatin cytotoxicity resulting from introduction of wild-type p53 gene in human osteosarcoma
-
Tsuchiya H., Mori Y., Ueda Y., Okada G., and Tomita K. Sensitization and caffeine potentiation of cisplatin cytotoxicity resulting from introduction of wild-type p53 gene in human osteosarcoma. Anticancer Res. 20 (2000) 235-242
-
(2000)
Anticancer Res.
, vol.20
, pp. 235-242
-
-
Tsuchiya, H.1
Mori, Y.2
Ueda, Y.3
Okada, G.4
Tomita, K.5
-
141
-
-
0141676267
-
Concurrent induction of T-cell activation and apoptosis of osteosarcoma cells by adenovirus-mediated B7-1/Fas chimeric gene transfer
-
Tsuji H., Kawaguchi S., Wada T., Nagoya S., Inobe M., Yagita H., et al. Concurrent induction of T-cell activation and apoptosis of osteosarcoma cells by adenovirus-mediated B7-1/Fas chimeric gene transfer. Cancer Gene Ther. 10 (2003) 717-725
-
(2003)
Cancer Gene Ther.
, vol.10
, pp. 717-725
-
-
Tsuji, H.1
Kawaguchi, S.2
Wada, T.3
Nagoya, S.4
Inobe, M.5
Yagita, H.6
-
142
-
-
0036708231
-
Adenovirus-mediated in vivo B7-1 gene transfer induces anti-tumor immunity against pre-established primary tumor and pulmonary metastasis of rat osteosarcoma
-
Tsuji H., Kawaguchi S., Wada T., Nagoya S., Inobe M., Yamashita T., et al. Adenovirus-mediated in vivo B7-1 gene transfer induces anti-tumor immunity against pre-established primary tumor and pulmonary metastasis of rat osteosarcoma. Cancer Gene Ther. 9 (2002) 747-755
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 747-755
-
-
Tsuji, H.1
Kawaguchi, S.2
Wada, T.3
Nagoya, S.4
Inobe, M.5
Yamashita, T.6
-
143
-
-
23944496641
-
Infectivity enhanced, hTERT promoter-based conditionally replicative adenoviruses are useful for SCLC treatment
-
Uchino J., Takayama K., Harada A., Kawakami Y., Inoue H., Curiel D.T., et al. Infectivity enhanced, hTERT promoter-based conditionally replicative adenoviruses are useful for SCLC treatment. Cancer Gene Ther. 12 (2005) 737-748
-
(2005)
Cancer Gene Ther.
, vol.12
, pp. 737-748
-
-
Uchino, J.1
Takayama, K.2
Harada, A.3
Kawakami, Y.4
Inoue, H.5
Curiel, D.T.6
-
144
-
-
33947159741
-
-
Unni, KK: General Aspects and data on 11,087 cases. Dahlin's Bone Tumors, pp. 143-183. Philadelphia: Lippincott-raven; 1996.
-
-
-
-
145
-
-
0036830143
-
Conditionally replicative adenovirus expressing p53 exhibits enhanced oncolytic potency
-
van Beusechem V.W., van den Doel P.B., Grill J., Pinedo H.M., and Gerritsen W.R. Conditionally replicative adenovirus expressing p53 exhibits enhanced oncolytic potency. Cancer Res. 62 (2002) 6165-6171
-
(2002)
Cancer Res.
, vol.62
, pp. 6165-6171
-
-
van Beusechem, V.W.1
van den Doel, P.B.2
Grill, J.3
Pinedo, H.M.4
Gerritsen, W.R.5
-
146
-
-
0036279332
-
Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer
-
van der Poel H.G., Molenaar B., van Beusechem V.W., Haisma H.J., Rodriguez R., Curiel D.T., et al. Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer. J. Urol. 168 (2002) 266-272
-
(2002)
J. Urol.
, vol.168
, pp. 266-272
-
-
van der Poel, H.G.1
Molenaar, B.2
van Beusechem, V.W.3
Haisma, H.J.4
Rodriguez, R.5
Curiel, D.T.6
-
147
-
-
0037087621
-
Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer
-
Vasey P.A., Shulman L.N., Campos S., Davis J., Gore M., Johnston S., et al. Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer. J. Clin. Oncol. 20 (2002) 1562-1569
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1562-1569
-
-
Vasey, P.A.1
Shulman, L.N.2
Campos, S.3
Davis, J.4
Gore, M.5
Johnston, S.6
-
148
-
-
33644988908
-
Delivery of viral vectors to tumor cells: extracellular transport, systemic distribution, and strategies for improvement
-
Wang Y., and Yuan F. Delivery of viral vectors to tumor cells: extracellular transport, systemic distribution, and strategies for improvement. Ann. Biomed. Eng. 34 (2006) 114-127
-
(2006)
Ann. Biomed. Eng.
, vol.34
, pp. 114-127
-
-
Wang, Y.1
Yuan, F.2
-
149
-
-
0034933606
-
Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors
-
Wesseling J.G., Bosma P.J., Krasnykh V., Kashentseva E.A., Blackwell J.L., Reynolds P.N., et al. Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors. Gene Ther. 8 (2001) 969-976
-
(2001)
Gene Ther.
, vol.8
, pp. 969-976
-
-
Wesseling, J.G.1
Bosma, P.J.2
Krasnykh, V.3
Kashentseva, E.A.4
Blackwell, J.L.5
Reynolds, P.N.6
-
150
-
-
0027166647
-
Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment
-
Wickham T.J., Mathias P., Cheresh D.A., and Nemerow G.R. Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 73 (1993) 309-319
-
(1993)
Cell
, vol.73
, pp. 309-319
-
-
Wickham, T.J.1
Mathias, P.2
Cheresh, D.A.3
Nemerow, G.R.4
-
151
-
-
0035392963
-
Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase
-
Wierdl M., Morton C.L., Weeks J.K., Danks M.K., Harris L.C., and Potter P.M. Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase. Cancer Res. 61 (2001) 5078-5082
-
(2001)
Cancer Res.
, vol.61
, pp. 5078-5082
-
-
Wierdl, M.1
Morton, C.L.2
Weeks, J.K.3
Danks, M.K.4
Harris, L.C.5
Potter, P.M.6
-
152
-
-
0033556003
-
Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase
-
Wildner O., Blaese R.M., and Morris J.C. Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase. Cancer Res. 59 (1999) 410-413
-
(1999)
Cancer Res.
, vol.59
, pp. 410-413
-
-
Wildner, O.1
Blaese, R.M.2
Morris, J.C.3
-
153
-
-
1642453767
-
Conditionally replicative adenovirus with tropism expanded towards integrins inhibits osteosarcoma tumor growth in vitro and in vivo
-
Witlox A.M., Van Beusechem V.W., Molenaar B., Bras H., Schaap G.R., Alemany R., et al. Conditionally replicative adenovirus with tropism expanded towards integrins inhibits osteosarcoma tumor growth in vitro and in vivo. Clin. Cancer Res. 10 (2004) 61-67
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 61-67
-
-
Witlox, A.M.1
Van Beusechem, V.W.2
Molenaar, B.3
Bras, H.4
Schaap, G.R.5
Alemany, R.6
-
154
-
-
13944265059
-
Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma
-
Witlox M.A., Van Beusechem V.W., Grill J., Haisma H.J., Schaap G., Bras J., et al. Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma. J. Gene Med. 4 (2002) 510-516
-
(2002)
J. Gene Med.
, vol.4
, pp. 510-516
-
-
Witlox, M.A.1
Van Beusechem, V.W.2
Grill, J.3
Haisma, H.J.4
Schaap, G.5
Bras, J.6
-
155
-
-
0033817517
-
Intranasal therapy with an adenoviral vector containing the murine interleukin-12 gene eradicates osteosarcoma lung metastases
-
Worth L.L., Jia S.F., Zhou Z., Chen L., and Kleinerman E.S. Intranasal therapy with an adenoviral vector containing the murine interleukin-12 gene eradicates osteosarcoma lung metastases. Clin. Cancer Res. 6 (2000) 3713-3718
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3713-3718
-
-
Worth, L.L.1
Jia, S.F.2
Zhou, Z.3
Chen, L.4
Kleinerman, E.S.5
-
156
-
-
0033771566
-
Hypoglycemic effect of insulin-transferrin conjugate in streptozotocin-induced diabetic rats
-
Xia C.Q., Wang J., and Shen W.C. Hypoglycemic effect of insulin-transferrin conjugate in streptozotocin-induced diabetic rats. J. Pharmacol. Exp. Ther. 295 (2000) 594-600
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 594-600
-
-
Xia, C.Q.1
Wang, J.2
Shen, W.C.3
-
157
-
-
0029886603
-
Enhanced tumor suppressor gene therapy via replication-deficient adenovirus vectors expressing an N-terminal truncated retinoblastoma protein
-
Xu H.J., Zhou Y., Seigne J., Perng G.S., Mixon M., Zhang C., et al. Enhanced tumor suppressor gene therapy via replication-deficient adenovirus vectors expressing an N-terminal truncated retinoblastoma protein. Cancer Res. 56 (1996) 2245-2249
-
(1996)
Cancer Res.
, vol.56
, pp. 2245-2249
-
-
Xu, H.J.1
Zhou, Y.2
Seigne, J.3
Perng, G.S.4
Mixon, M.5
Zhang, C.6
-
158
-
-
27644441812
-
Immune response and effect of adenovirus-mediated human BMP-2 gene transfer on the repair of segmental tibial bone defects in goats
-
Xu X.L., Tang T., Dai K., Zhu Z., Guo X.E., Yu C., et al. Immune response and effect of adenovirus-mediated human BMP-2 gene transfer on the repair of segmental tibial bone defects in goats. Acta Orthop. 76 (2005) 637-646
-
(2005)
Acta Orthop.
, vol.76
, pp. 637-646
-
-
Xu, X.L.1
Tang, T.2
Dai, K.3
Zhu, Z.4
Guo, X.E.5
Yu, C.6
-
159
-
-
0141483028
-
Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer
-
Yamamoto M., Davydova J., Wang M., Siegal G.P., Krasnykh V., Vickers S.M., et al. Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer. Gastroenterology 125 (2003) 1203-1218
-
(2003)
Gastroenterology
, vol.125
, pp. 1203-1218
-
-
Yamamoto, M.1
Davydova, J.2
Wang, M.3
Siegal, G.P.4
Krasnykh, V.5
Vickers, S.M.6
-
160
-
-
0035872445
-
Identification of the transcriptional regulatory sequences of human calponin promoter and their use in targeting a conditionally replicating herpes vector to malignant human soft tissue and bone tumors
-
Yamamura H., Hashio M., Noguchi M., Sugenoya Y., Osakada M., Hirano N., et al. Identification of the transcriptional regulatory sequences of human calponin promoter and their use in targeting a conditionally replicating herpes vector to malignant human soft tissue and bone tumors. Cancer Res. 61 (2001) 3969-3977
-
(2001)
Cancer Res.
, vol.61
, pp. 3969-3977
-
-
Yamamura, H.1
Hashio, M.2
Noguchi, M.3
Sugenoya, Y.4
Osakada, M.5
Hirano, N.6
-
161
-
-
0034652615
-
ONYX-015 works synergistically with chemotherapy in lung cancer cell lines and primary cultures freshly made from lung cancer patients
-
You L., Yang C.T., and Jablons D.M. ONYX-015 works synergistically with chemotherapy in lung cancer cell lines and primary cultures freshly made from lung cancer patients. Cancer Res. 60 (2000) 1009-1013
-
(2000)
Cancer Res.
, vol.60
, pp. 1009-1013
-
-
You, L.1
Yang, C.T.2
Jablons, D.M.3
-
162
-
-
21344464386
-
Combined bone morphogenetic protein-2 and-7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model
-
Zhu W., Rawlins B.A., Boachie-Adjei O., Myers E.R., Arimizu J., Choi E., et al. Combined bone morphogenetic protein-2 and-7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model. J. Bone Miner. Res. 19 (2004) 2021-2032
-
(2004)
J. Bone Miner. Res.
, vol.19
, pp. 2021-2032
-
-
Zhu, W.1
Rawlins, B.A.2
Boachie-Adjei, O.3
Myers, E.R.4
Arimizu, J.5
Choi, E.6
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