Concurrent induction of T-cell activation and apoptosis of osteosarcoma cells by adenovirus-mediated B7-1/Fas chimeric gene transfer

Cancer Gene Therapy

Volumn 10, Issue 9, 2003, Pages 717-725

  Tsuji, Hideki ^a,b   Kawaguchi, Satoshi ^a   Wada, Takuro ^a   Nagoya, Satoshi ^a   Inobe, Manabu ^b   Yagita, Hideo ^c   Okumura, Ko ^c   Yamashita, Toshihiko ^a   Uede, Toshimitsu ^b  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adenovirus; Apoptosis; B7 1; Chimeric gene; Fas; Osteosarcoma

Indexed keywords

ADENOVIRUS VECTOR; B7 ANTIGEN; CHIMERIC PROTEIN; FAS ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY B7 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER IMMUNOTHERAPY; CANCER SURVIVAL; CLINICAL PROTOCOL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; IMMUNOGENICITY; IN VITRO STUDY; LUNG METASTASIS; MALE; MOUSE; NONHUMAN; OSTEOSARCOMA; OSTEOSARCOMA CELL; PRIORITY JOURNAL; RAT; T LYMPHOCYTE ACTIVATION;

ADENOVIRIDAE; ANIMALS; ANTIGENS, CD80; ANTIGENS, CD95; APOPTOSIS; CELL LINE, TUMOR; CELLS, CULTURED; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; IMMUNOTHERAPY; LYMPHOCYTE ACTIVATION; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS; OSTEOSARCOMA; RATS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

ADENOVIRIDAE; ANIMALIA; MURINAE;

EID: 0141676267     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700624     Document Type: Article

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