Growth suppression of established human osteosarcoma lung metastases in mice by aerosol gene therapy with PEI-p53 complexes

Cancer Gene Therapy

Volumn 8, Issue 9, 2001, Pages 619-627

  Densmore, Charles L ^a   Kleinerman, Eugenie S ^b   Gautam, Ajay ^a   Jia, Shu Fang ^b   Xu, Bo ^a   Worth, Laura L ^b   Waldrep, J Clifford ^a   Fung, Yuen Kai ^c,d   T'Ang, Anne ^c,d   Knight, Vernon ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c CHILDREN S HOSPITAL LOS ANGELES   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Aerosol; Gene therapy; Lung cancer; Osteosarcoma; p53; Polyethyleneimine

Indexed keywords

PLASMID DNA; POLYETHYLENEIMINE; PROTEIN P53; VIRUS VECTOR;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DELETION MUTANT; DRUG FORMULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE INACTIVATION; GENE THERAPY; GENETIC TRANSFECTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG METASTASIS; MOUSE; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; TUMOR VOLUME;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; BONE NEOPLASMS; CELL DIVISION; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE THERAPY; GENES, P53; GENETIC VECTORS; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; OSTEOSARCOMA; POLYETHYLENEIMINE; SPECIFIC PATHOGEN-FREE ORGANISMS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0034804767     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700343     Document Type: Article

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