New insights into Vitamin D sterol-VDR proteolysis, allostery, structure-function from the perspective of a conformational ensemble model

Journal of Steroid Biochemistry and Molecular Biology

Volumn 103, Issue 3-5, 2007, Pages 243-262

  Mizwicki, Mathew T ^a   Bula, Craig M ^a   Bishop, June E ^a   Norman, Anthony W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

1 ,25(OH)2 Vitamin D3; Conformational ensemble; Induced fit; Structure function; VDR; Vitamin D receptor

Indexed keywords

CALCITRIOL; STEROL; TRYPSIN; VITAMIN D; VITAMIN D RECEPTOR;

ALLOSTERISM; ARTICLE; LIGAND BINDING; METABOLITE; MOLECULAR MODEL; MUTAGENESIS; PROTEIN DEGRADATION; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

ALLOSTERIC SITE; CELL LINE; ELECTROSTATICS; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CALCITRIOL; TRYPSIN; VITAMIN D;

EID: 33947165807     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2006.12.004     Document Type: Article

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