Characterization of a novel analogue of 1α,25(OH)2-vitamin D3 with two side chains: Interaction with its nuclear receptor and cellular actions

Journal of Medicinal Chemistry

Volumn 43, Issue 14, 2000, Pages 2719-2730

  Norman, Anthony W ^a   Manchand, Percy S ^c   Uskokovic, Milan R ^c   Okamura, William H ^b   Takeuchi, Janet A ^b   Bishop, June E ^a   Hisatake, Jun Iichi ^d   Koeffler, H Phillip ^d   Peleg, Sara ^e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL DERIVATIVE; CALCITRIOL RECEPTOR; OSTEOPONTIN; PROTEINASE;

ARTICLE; BINDING SITE; CELL STRAIN HL 60; CELL STRAIN MCF 7; COLONY FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA TRANSCRIPTION; GENETIC TRANSFECTION; HORMONE RECEPTOR INTERACTION; HORMONE STRUCTURE; HUMAN; HUMAN CELL; LIGAND BINDING; PROMOTER REGION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TRANSCRIPTION REGULATION;

ANIMALS; BINDING, COMPETITIVE; CALCITRIOL; CELL DIVISION; CELL LINE; CHICKENS; CLONE CELLS; HUMANS; LIGANDS; MODELS, MOLECULAR; OSTEOPONTIN; PROMOTER REGIONS (GENETICS); PROTEIN CONFORMATION; RECEPTORS, CALCITRIOL; RECEPTORS, SOMATOTROPIN; RECOMBINANT FUSION PROTEINS; RESPONSE ELEMENTS; SIALOGLYCOPROTEINS; THYMIDINE KINASE; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0034644190     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0000160     Document Type: Article

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