Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain

Journal of Biological Chemistry

Volumn 272, Issue 38, 1997, Pages 23547-23551

  MacPhee, Ian J ^a   Barker, Philip A ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CERAMIDE DERIVATIVE; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROTROPHIN RECEPTOR; PHOSPHOSERINE; PROTEIN C FOS; PROTEIN TYROSINE KINASE; RECEPTOR PROTEIN; SPHINGOMYELIN PHOSPHODIESTERASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; PC12 CELLS; PHOSPHORYLATION; PROTEIN BINDING; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, NERVE GROWTH FACTOR; RECEPTOR, TRKA; RECEPTORS, NERVE GROWTH FACTOR; SERINE; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0030752208     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.38.23547     Document Type: Article

References (38)

1. Klein, R., Smeyne, R. J., Wurst, W., Long, L. K., Auerbach, B. A., Joyner, A. L., and Barbacid, M. (1993) Cell 75, 113-122
2. Smeyne, R. J., Klein, R., Schnapp, A., Long, L. K., Bryant, S., Lewin, A., Lira, S. A., and Barbacid, M. (1994) Nature 368, 246-249
3. Klein, R., Silos, S. I., Smeyne, R. J., Lira, S. A., Brambilla, R., Bryant, S., Zhang, L., Snider, W. D., and Barbacid, M. (1994) Nature 368, 249-251
4. Crowley, C., Spencer, S. D., Nishimura, M. C., Chen, K. S., Pitts, M. S., Armanini, M. P., Ling, L. H., McMahon, S. B., Shelton, D. L., Levinson, A. D., and Phillips, H. S. (1994) Cell 76, 1001-1011
5. Ernfors, P., Lee, K. F., and Jaenisch, R. (1994) Nature 368, 147-150
6. Ernfors, P., Lee, K.-F., Kucera, J., and Jaenisch, R. (1994) Cell 77, 503-512
7. Jones, K. R., Fariñas, I., Backus, C., and Reichardt, L. F. (1994) Cell 76, 989-999
8. Bazan, J. F. (1993) Curr. Biol. 3, 603-606
9. Barker, P. A., Barbee, G., Misko, T. P., and Shooter, E. M. (1994) J. Biol. Chem. 269, 30645-30650
10. Hantzopoulos, P. A., Suri, C., Glass, D. J., Goldfarb, M. P., and Yancopoulos, G. D. (1994) Neuron 13, 187-201
11. Verdi, J. M., Birren, S. J., Ibanez, C. F., Persson, H., Kaplan, D. R., Benedetti, M., Chao, M. V., and Anderson, D. J. (1994) Neuron 12, 733-745
12. Barker, P. A., and Shooter, E. M. (1994) Neuron 13, 203-215
13. Mahadeo, D., Kaplan, L., Chao, M. V., and Hempstead, B. L. (1994) J. Biol. Chem. 269, 6884-6891
14. Dobrowsky, R. T., Werner, M. H., Castellino, A. M., Chao, M. V., and Hannun, Y. A. (1994) Science 265, 1596-1598
15. Dobrowsky, R. T., Jenkins, G. M., and Hannun, Y. A. (1995) J. Biol. Chem. 270, 22135-22142
16. Carter, B. D., Kaltschmidt, C., Kaltschmidt, B., Offenhauser, N., Bohmmatthaei, R., Baeuerle, P. A., and Barde, Y. A. (1996) Science 272, 542-545
17. Braccilaudiero, L., Aloe, L., Stenfors, C., Tirassa, P., Theodorsson, E., and Lundberg, T. (1996) Neuroreport 7, 485-488
18. Greene, L. A., and Tischler, A. S. (1976) Proc. Natl. Acad. Sci. U. S. A. 73, 2424-2428
19. Hempstead, B. L., Rabin, S. J., Kaplan, L., Reid, S., Parada, L. F., and Kaplan, D. R. (1992) Neuron 9, 883-896
20. Barker, P. A., Lomen-Hoerth, C., Gensch, E. M., Meakin, S. O., Glass, D. J., and Shooter, E. M. (1993) J. Biol. Chem. 268, 15150-15157
21. Ibanez, C. F., Ebendal, T., Barbany, G., Murray-Rust, J., Blundell, T. L., and Persson, H. (1992) Cell 69, 329-341
22. Theroux, S. J., Latour, D. A., Stanley, K., Raden, D. L., and Davis, R. J. (1992) J. Biol. Chem. 267, 16620-16626
23. Tanti, J.-F., Gremeaux, T., Van Obberghen, E., and Le Marchand-Brustel, Y. (1994) J. Biol. Chem. 269, 6051-6057
24. Olson, J. E., and Pledger, W. J. (1990) J. Biol. Chem. 265, 1847-1851
25. Lewis, R. E., Volle, D. J., and Sanderson, S. D. (1994) J. Biol. Chem. 269, 26259-26266
26. Davies, A. M., Lee, K. F., and Jaenisch, R. (1993) Neuron 11, 565-574
27. Ip, N. Y., Stitt, T. N., Tapley, P., Klein, R., Glass, D. J., Fandl, J., Greene, L. A., Barbacid, M., and Yancopoulos, G. D. (1993) Neuron 10, 137-149
28. Berkemeier L. R., Winslow, J. W., Kaplan, D. R., Nikolics, K., Goeddel, D. V., and Rosenthal, A. (1991) Neuron 7, 857-866
29. Benedetti, M., Levi, A., and Chao, M. V. (1994) Proc. Natl. Acad. Sci. U. S. A. 90, 7859-7863
30. Northwood, I. C., and Davis, R. J. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 6107-6111
31. Countaway, J. L., Northwood, I. C., and Davis, R. J. (1989) J. Biol. Chem. 264, 10828-10835
32. Kanety, H., Feinstein, R., Papa, M. Z., Hemi, R., and Karasik, A. (1995) J. Biol. Chem. 270, 23780-23784
33. Kanety, H., Hemi, R., Papa, M. Z., and Karasik, A. (1996) J. Biol. Chem. 271, 9895-9897
34. Feinstein, R., Kanety, H., Papa, M. Z., Lunenfeld, B., and Karasik, A. (1993) J. Biol. Chem. 268, 26055-26058
35. Hotamisligil, G., Murray, D., Choy, L., and Spiegelman, B. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 4854-4858
36. Hotamisligil, G., Peraldi, P., Budavari, A., Ellis, R., White, M., and Spiegelman, B. (1996) Science 271, 665-668
37. Peraldi, P., Hotamisligil, G. S., Buurman, W. A., White, M. F., and Spiegelman, B. M. (1996) J. Biol. Chem. 271, 13018-13022
38. Mothe, I., and Van Obberghen, E. (1996) J. Biol. Chem. 271, 11222-11227