Epac mediates a cAMP-to-PKC signaling in inflammatory pain: An isolectin B4(+) neuron-specific mechanism

Journal of Neuroscience

Volumn 25, Issue 26, 2005, Pages 6119-6126

  Hucho, Tim B ^a   Dina, Olayinka A ^a   Levine, Jon D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

adrenergic receptor; cAMP; Epac; IB4; Inflammation; Intracellular signaling; Nociception; PKC; PLD

Indexed keywords

CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR EPAC; ISOLECTIN B4; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; PHOSPHOLIPASE D; PROTEIN KINASE C EPSILON; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HYPERALGESIA; INFLAMMATION; MALE; MECHANICAL STIMULATION; NEUROPATHIC PAIN; NOCICEPTION; NOCICEPTIVE RECEPTOR; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; SECOND MESSENGER; SENSORY NERVE CELL; SPINAL GANGLION;

ANIMALS; CYCLIC AMP; GANGLIA, SPINAL; GLYCOPROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INFLAMMATION; LECTINS; MALE; NEURONS; ORGAN CULTURE TECHNIQUES; PAIN; PROTEIN KINASE C; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 21544452743     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0285-05.2005     Document Type: Article

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