Acute sensitization by NGF of the response of small-diameter sensory neurons to capsaicin

Journal of Neurophysiology

Volumn 86, Issue 6, 2001, Pages 2931-2938

  Shu, X ^a   Mendell, L M ^a  

^a State University of New York at Stony Brook ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BISINDOLYLMALEIMIDE; CAPSAICIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; MITOGEN ACTIVATED PROTEIN KINASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NERVE GROWTH FACTOR; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; ENZYME INHIBITION; HYPERALGESIA; NONHUMAN; PRIORITY JOURNAL; RAT; SECOND MESSENGER; SENSITIZATION; SENSORY NERVE CELL; SPINAL GANGLION; TACHYPHYLAXIS;

EID: 0035211454     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2001.86.6.2931     Document Type: Article

References (52)

1. Peripheral administration of nerve growth factor in the adult rat produces a thermal hyperalgesia that requires the presence of sympathetic post-ganglionic neurones
2. Bradykinin and serotonin effects on various types of cutaneous nerve fibers
3. Nerve growth factor evokes hyperalgesia in mice lacking the low-affinity neurotrophin receptor p75
4. Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism
5. The vanilloid receptor: A molecular gateway to the pain pathway
6. Impaired nociception and pain sensation in mice lacking the capsaicin receptor
7. The capsaicin receptor: A heat-activated ion channel in the pain pathway
8. Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat
9. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC 12D pheochromocytoma cells
10. Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
11. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
12. The cAMP transduction cascade mediates the PGE2-induced inhibition of potassium currents in rat sensory neurones
13. Distinct signalling pathways mediate the cAMP response element (CRE)-dependent activation of the calcitonin gene-related peptide gene promoter by cAMP and nerve growth factor
14. Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells
15. Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat sensory neurons in vitro
16. Changes in cytosolic calcium in response to noxious heat and their relationship to vanilloid receptors in rat dorsal root ganglion neurons
17. Prostaglandins facilitate peptide release from rat sensory neurons by activating the adenosine 3′.5′-cyclic monophosphate transduction cascade
18. Nerve growth factor acts through cAMP-dependent protein kinase to increase the number of sodium channels in PC12 cells
19. PI-3 kinase and IP3 partners in NT3-induced synaptic transmission
20. A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice
21. The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons
22. Comparison of responses of warm and nociceptive C-fiber afferents in monkey with human judgments of thermal pain
23. Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin
24. The cAMP-dependent kinase pathway does not sensitize the cloned vanilloid receptor type 1 expressed in xenopus oocytes or Aplysia neurons
25. Inflammatory pain
26. Nerve growth factor-induced hyperalgesia in the neonatal and adult rat
27. Peripheral and central mechanisms of NGF-induced hyperalgesia
28. The role of calcium and protein kinase C in the IgE-dependent activation of phosphatidylcholine-specific phospholipase D in a rat mast (RBL 2H3) cell line
29. Capsaicin inhibits activation of voltage-gated sodium currents in capsaicin-sensitive trigeminal ganglion neurons
30. Activation and recovery of the PGE2-mediated sensitization of the capsaicin response in rat sensory neurons
31. The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: Whole-cell and single-channel studies
32. Leukotriene and prostaglandin sensitization of cutaneous high-threshold C- and A-delta mechanonociceptors in the hairy skin of rat hindlimbs
33. Ion channels of nociception
34. The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule
35. Peripheral mechanisms of nociception
36. Similarities and differences between the responses of rat sensory neurons to noxious heat and capsaicin
37. Effect of protons on the inward current evoked by capsaicin in isolated dorsal root ganglion cells
38. Prostaglandins sensitize nociceptors in cell culture
39. Characteristics of nerve growth factor induced hyperalgesia in adult rats: Dependence on enhanced bradykinin-1 receptor activity but not neurokinin-1 receptor activation
40. Nerve growth factor and NT-5 induce increased thermal sensitivity of cutaneous nociceptors in vitro
41. Effect of trkB and trkC neurotrophin receptor agonists on thermal nociception: A behavioral and electrophysiological study
42. Nerve growth factor acutely sensitizes the response of adult rat sensory neurons to capsaicin
43. Acute effects of NGF on capsaicin currents in rat DRG cells do not require Ca and are modulated by manipulation of PKA levels
44. Neurotrophins and hyperalgesia
45. The cloned capsaicin receptor integrates multiple pain-producing stimuli
46. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C
47. Calcium depletion and repletion in cultured chick heart muscle cells
48. An enzyme-linked immunoassay for nerve growth factor (NGF): A tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues
49. Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity
50. Neuronal plasticity: Increasing the gain in pain
51. PI-3 kinase and IP3 are both necessary and sufficient to mediate NT3induced synaptic potentiation
52. Phorbol ester-induced inhibition of potassium currents in rat sensory neurons requires voltage-dependent entry of calcium