Yeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulation

PLoS Pathogens

Volumn 3, Issue 2, 2007, Pages 0179-0190

  Kramer, Roger W ^a   Slagowski, Naomi L ^a   Eze, Ngozi A ^a   Giddings, Kara S ^b   Morrison, Monica F ^a   Siggers, Keri A ^a   Starnbach, Michael N ^b   Lesser, Cammie F ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN OSPF; UNCLASSIFIED DRUG; CHITIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CELL DISRUPTION; CELL FUNCTION; CELL WALL; CONTROLLED STUDY; DISEASE MODEL; ENZYME ACTIVATION; ENZYME INHIBITION; EXPERIMENTAL MOUSE; FEMALE; FUNCTIONAL GENOMICS; GENE CONTROL; GENE DELETION; GENETIC SCREENING; HAPLOIDY; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNOREGULATION; INNATE IMMUNITY; LUNG INFECTION; MAMMAL; MICROARRAY ANALYSIS; MOUSE; MUTANT; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE; SHIGELLA; SHIGELLOSIS; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; SYSTEMS BIOLOGY; TARGET CELL; YEAST; YEAST CELL; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; GENOME; IMMUNOLOGY; METABOLISM; OPEN READING FRAME; PATHOGENICITY; PHENOTYPE; PHOSPHORYLATION; PHYSIOLOGY; SHIGELLA FLEXNERI;

BACTERIA (MICROORGANISMS); MAMMALIA; SACCHAROMYCES CEREVISIAE; SHIGELLA;

ANIMALS; BACTERIAL PROTEINS; CELL WALL; CHITIN; DYSENTERY, BACILLARY; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, FUNGAL; IMMUNITY, NATURAL; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; OPEN READING FRAMES; PHENOTYPE; PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; SHIGELLA FLEXNERI;

EID: 33847269135     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0030021     Document Type: Article

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