메뉴 건너뛰기




Volumn 39, Issue 1, 2007, Pages 26-45

Molecular targets in gynaecological cancers

Author keywords

Expression profiling; HPV; Individualised therapy; Methylation; Molecular targets; Telomerase

Indexed keywords

ANGIOGENESIS INHIBITOR; CETUXIMAB; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; GEFITINIB; HER2 PROTEIN INHIBITOR; IMATINIB; LAPATINIB; MAMMALIAN TARGET OF RAPAMYCIN; PERTUZUMAB; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P16INK4A; PROTEIN TYROSINE KINASE INHIBITOR; RNA; TELOMERASE; TRANSCRIPTOME; TRASTUZUMAB; TUMOR MARKER; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 33847229125     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1080/00313020601153273     Document Type: Article
Times cited : (14)

References (281)
  • 1
    • 13144279272 scopus 로고    scopus 로고
    • Apply innovative technologies to explore cancer genome
    • Shih Ie M, Wang TL. Apply innovative technologies to explore cancer genome. Curr Opin Oncol 2005; 17: 33-8.
    • (2005) Curr Opin Oncol , vol.17 , pp. 33-38
    • Shih, I.M.1    Wang, T.L.2
  • 2
    • 33744730025 scopus 로고    scopus 로고
    • Personalized medicine and development of targeted therapies: The upcoming challenge for diagnostic molecular pathology. A review
    • Dietel M, Sers C. Personalized medicine and development of targeted therapies: the upcoming challenge for diagnostic molecular pathology. A review. Virchows Arch 2006; 448: 744-55.
    • (2006) Virchows Arch , vol.448 , pp. 744-755
    • Dietel, M.1    Sers, C.2
  • 3
    • 0035061867 scopus 로고    scopus 로고
    • Tissue microarray technology for high-throughput molecular profiling of cancer
    • Kallioniemi OP, Wagner U, Kononen J, Sauter G. Tissue microarray technology for high-throughput molecular profiling of cancer. Hum Mol Genet 2001; 10: 657-62.
    • (2001) Hum Mol Genet , vol.10 , pp. 657-662
    • Kallioniemi, O.P.1    Wagner, U.2    Kononen, J.3    Sauter, G.4
  • 4
    • 1542270084 scopus 로고    scopus 로고
    • Applications of microarrays to histopathology
    • van de Rijn M, Gilks CB. Applications of microarrays to histopathology. Histopathology 2004; 44: 97-108.
    • (2004) Histopathology , vol.44 , pp. 97-108
    • van de Rijn, M.1    Gilks, C.B.2
  • 5
    • 0242405575 scopus 로고    scopus 로고
    • Advantages and limitations of microarray technology in human cancer
    • Russo G, Zegar C, Giordano A. Advantages and limitations of microarray technology in human cancer. Oncogene 2003; 22: 6497-507.
    • (2003) Oncogene , vol.22 , pp. 6497-6507
    • Russo, G.1    Zegar, C.2    Giordano, A.3
  • 6
    • 0037306760 scopus 로고    scopus 로고
    • New technologies for the identification of markers for early detection of ovarian cancer
    • Bandera CA, Ye B, Mok SC. New technologies for the identification of markers for early detection of ovarian cancer. Curr Opin Obstet Gynecol 2003; 15: 51-5.
    • (2003) Curr Opin Obstet Gynecol , vol.15 , pp. 51-55
    • Bandera, C.A.1    Ye, B.2    Mok, S.C.3
  • 8
    • 24644468625 scopus 로고    scopus 로고
    • Emerging issues of the expression profiling technologies for the study of gynecologic cancer
    • Pappa KI, Anagnou NP. Emerging issues of the expression profiling technologies for the study of gynecologic cancer. Am J Obstet Gynecol 2005; 193: 908-18.
    • (2005) Am J Obstet Gynecol , vol.193 , pp. 908-918
    • Pappa, K.I.1    Anagnou, N.P.2
  • 9
    • 14844318528 scopus 로고    scopus 로고
    • Pathology of the future: Molecular profiling for targeted therapy
    • Espina V, Geho D, Mehta AI, et al. Pathology of the future: molecular profiling for targeted therapy. Cancer Invest 2005; 23: 36-46.
    • (2005) Cancer Invest , vol.23 , pp. 36-46
    • Espina, V.1    Geho, D.2    Mehta, A.I.3
  • 10
    • 0035350918 scopus 로고    scopus 로고
    • The application of tissue microarrays to cancer research
    • Horvath L, Henshall S. The application of tissue microarrays to cancer research. Pathology 2001; 33: 125-9.
    • (2001) Pathology , vol.33 , pp. 125-129
    • Horvath, L.1    Henshall, S.2
  • 11
    • 20444480567 scopus 로고    scopus 로고
    • Technology insight: Identification of biomarkers with tissue microarray technology
    • Giltnane JM, Rimm DL. Technology insight: Identification of biomarkers with tissue microarray technology. Nat Clin Pract Oncol 2004; 1: 104-11.
    • (2004) Nat Clin Pract Oncol , vol.1 , pp. 104-111
    • Giltnane, J.M.1    Rimm, D.L.2
  • 12
    • 10644257285 scopus 로고    scopus 로고
    • Association of 20q13.2 copy number changes with the advanced stage of ovarian cancer-tissue microarray analysis
    • Dimova I, Yosifova A, Zaharieva B, et al. Association of 20q13.2 copy number changes with the advanced stage of ovarian cancer-tissue microarray analysis. Eur J Obstet Gynecol Reprod Biol 2005; 118: 81-5.
    • (2005) Eur J Obstet Gynecol Reprod Biol , vol.118 , pp. 81-85
    • Dimova, I.1    Yosifova, A.2    Zaharieva, B.3
  • 13
    • 27144434397 scopus 로고    scopus 로고
    • Profiling cytochrome P450 expression in ovarian cancer: Identification of prognostic markers
    • Downie D, McFadyen MC, Rooney PH, et al. Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers. Clin Cancer Res 2005; 11: 7369-75.
    • (2005) Clin Cancer Res , vol.11 , pp. 7369-7375
    • Downie, D.1    McFadyen, M.C.2    Rooney, P.H.3
  • 14
    • 33745451273 scopus 로고    scopus 로고
    • Tissue array analysis of expression microarray candidates identifies markers associated with tumor grade and outcome in serous epithelial ovarian cancer
    • Ouellet V, Guyot MC, Le Page C, et al. Tissue array analysis of expression microarray candidates identifies markers associated with tumor grade and outcome in serous epithelial ovarian cancer. Int J Cancer 2006; 119: 599-607.
    • (2006) Int J Cancer , vol.119 , pp. 599-607
    • Ouellet, V.1    Guyot, M.C.2    Le Page, C.3
  • 15
    • 33646418390 scopus 로고    scopus 로고
    • Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma
    • Zhang L, Huang J, Yang N, et al. Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma. Cancer Res 2006; 66: 4627-35.
    • (2006) Cancer Res , vol.66 , pp. 4627-4635
    • Zhang, L.1    Huang, J.2    Yang, N.3
  • 16
    • 33746742412 scopus 로고    scopus 로고
    • Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinoma
    • Lassus H, Sihto H, Leminen A, et al. Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinoma. J Mol Med 2006; 84: 671-81.
    • (2006) J Mol Med , vol.84 , pp. 671-681
    • Lassus, H.1    Sihto, H.2    Leminen, A.3
  • 17
    • 33745776277 scopus 로고    scopus 로고
    • Analysis of gene amplification and prognostic markers in ovarian cancer using comparative genomic hybridization for microarrays and immunohistochemical analysis for tissue microarrays
    • Mayr D, Kanitz V, Anderegg B, et al. Analysis of gene amplification and prognostic markers in ovarian cancer using comparative genomic hybridization for microarrays and immunohistochemical analysis for tissue microarrays. Am J Clin Pathol 2006; 126: 101-9.
    • (2006) Am J Clin Pathol , vol.126 , pp. 101-109
    • Mayr, D.1    Kanitz, V.2    Anderegg, B.3
  • 18
    • 3042672714 scopus 로고    scopus 로고
    • Validation of tissue microarray technology in ovarian carcinoma
    • Rosen DG, Huang X, Deavers MT, et al. Validation of tissue microarray technology in ovarian carcinoma. Mod Pathol 2004; 17: 790-7.
    • (2004) Mod Pathol , vol.17 , pp. 790-797
    • Rosen, D.G.1    Huang, X.2    Deavers, M.T.3
  • 19
    • 0032848246 scopus 로고    scopus 로고
    • Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas
    • Schummer M, Ng WV, Bumgarner RE, et al. Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas. Gene 1999; 238: 375-85.
    • (1999) Gene , vol.238 , pp. 375-385
    • Schummer, M.1    Ng, W.V.2    Bumgarner, R.E.3
  • 20
    • 0035970050 scopus 로고    scopus 로고
    • Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer
    • Welsh JB, Zarrinkar PP, Sapinoso LM, et al. Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer. Proc Natl Acad Sci USA 2001; 98: 1176-81.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1176-1181
    • Welsh, J.B.1    Zarrinkar, P.P.2    Sapinoso, L.M.3
  • 21
    • 0035397380 scopus 로고    scopus 로고
    • Changes in gene expression during progression of ovarian carcinoma
    • Tapper J, Kettunen E, El-Rifai W, et al. Changes in gene expression during progression of ovarian carcinoma. Cancer Genet Cytogenet 2001; 128: 1-6.
    • (2001) Cancer Genet Cytogenet , vol.128 , pp. 1-6
    • Tapper, J.1    Kettunen, E.2    El-Rifai, W.3
  • 22
    • 12344322308 scopus 로고    scopus 로고
    • Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma
    • Xie D, Lau SH, Sham JS, et al. Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma. Cancer 2005; 103: 277-83.
    • (2005) Cancer , vol.103 , pp. 277-283
    • Xie, D.1    Lau, S.H.2    Sham, J.S.3
  • 23
    • 22744445380 scopus 로고    scopus 로고
    • Discrimination between serous low malignant potential and invasive epithelial ovarian tumors using molecular profiling
    • Ouellet V, Provencher DM, Maugard CM, et al. Discrimination between serous low malignant potential and invasive epithelial ovarian tumors using molecular profiling. Oncogene 2005; 24: 4672-87.
    • (2005) Oncogene , vol.24 , pp. 4672-4687
    • Ouellet, V.1    Provencher, D.M.2    Maugard, C.M.3
  • 24
    • 1542329149 scopus 로고    scopus 로고
    • Predicting biomarkers for ovarian cancer using gene-expression microarrays
    • Adib TR, Henderson S, Perrett C, et al. Predicting biomarkers for ovarian cancer using gene-expression microarrays. Br J Cancer 2004; 90: 686-92.
    • (2004) Br J Cancer , vol.90 , pp. 686-692
    • Adib, T.R.1    Henderson, S.2    Perrett, C.3
  • 25
    • 17844377553 scopus 로고    scopus 로고
    • Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma
    • Sheehan KM, Calvert VS, Kay EW, et al. Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma. Mol Cell Proteomics 2005; 4: 346-55.
    • (2005) Mol Cell Proteomics , vol.4 , pp. 346-355
    • Sheehan, K.M.1    Calvert, V.S.2    Kay, E.W.3
  • 26
    • 33645241277 scopus 로고    scopus 로고
    • Gulmann C, Sheehan KM, Kay EW, Liotta LA, Petricoin EF 3rd. Array-based proteomics: mapping of protein circuitries for diagnostics, prognostics, and therapy guidance in cancer. J Pathol 2006; 208: 595-606.
    • Gulmann C, Sheehan KM, Kay EW, Liotta LA, Petricoin EF 3rd. Array-based proteomics: mapping of protein circuitries for diagnostics, prognostics, and therapy guidance in cancer. J Pathol 2006; 208: 595-606.
  • 27
    • 33748992592 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer
    • Duan Z, Foster R, Bell DA, et al. Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer. Clin Cancer Res 2006; 12: 5055-63.
    • (2006) Clin Cancer Res , vol.12 , pp. 5055-5063
    • Duan, Z.1    Foster, R.2    Bell, D.A.3
  • 28
    • 25444450573 scopus 로고    scopus 로고
    • Abnormalities of the RB1 pathway in ovarian serous papillary carcinoma as determined by overexpression of the p16(INK4A) protein
    • Armes JE, Lourie R, de Silva M, et al. Abnormalities of the RB1 pathway in ovarian serous papillary carcinoma as determined by overexpression of the p16(INK4A) protein. Int J Gynecol Pathol 2005; 24: 363-8.
    • (2005) Int J Gynecol Pathol , vol.24 , pp. 363-368
    • Armes, J.E.1    Lourie, R.2    de Silva, M.3
  • 29
    • 0037205527 scopus 로고    scopus 로고
    • DNA microarrays for assessing ovarian cancer gene expression
    • Haviv I, Campbell IG. DNA microarrays for assessing ovarian cancer gene expression. Mol Cell Endocrinol 2002; 191: 121-6.
    • (2002) Mol Cell Endocrinol , vol.191 , pp. 121-126
    • Haviv, I.1    Campbell, I.G.2
  • 30
    • 0141816860 scopus 로고    scopus 로고
    • Diagnostic markers that distinguish colon and ovarian adenocarcinomas: Identification by genomic, proteomic, and tissue array profiling
    • Nishizuka S, Chen ST, Gwadry FG, et al. Diagnostic markers that distinguish colon and ovarian adenocarcinomas: identification by genomic, proteomic, and tissue array profiling. Cancer Res 2003; 63: 5243-50.
    • (2003) Cancer Res , vol.63 , pp. 5243-5250
    • Nishizuka, S.1    Chen, S.T.2    Gwadry, F.G.3
  • 31
    • 33645351424 scopus 로고    scopus 로고
    • Molecular prognostic markers in ovarian cancer: Toward patient-tailored therapy
    • Crijns AP, Duiker EW, de Jong S, et al. Molecular prognostic markers in ovarian cancer: toward patient-tailored therapy. Int J Gynecol Cancer 2006; 16 (Suppl 1): 152-65.
    • (2006) Int J Gynecol Cancer , vol.16 , Issue.SUPPL. 1 , pp. 152-165
    • Crijns, A.P.1    Duiker, E.W.2    de Jong, S.3
  • 32
    • 0742272546 scopus 로고    scopus 로고
    • ERBB2 amplification is superior to protein expression status in predicting patient outcome in serous ovarian carcinoma
    • Lassus H, Leminen A, Vayrynen A, et al. ERBB2 amplification is superior to protein expression status in predicting patient outcome in serous ovarian carcinoma. Gynecol Oncol 2004; 92: 31-9.
    • (2004) Gynecol Oncol , vol.92 , pp. 31-39
    • Lassus, H.1    Leminen, A.2    Vayrynen, A.3
  • 33
    • 9944239917 scopus 로고    scopus 로고
    • Her-2/neu expression and amplification in early stage ovarian surface epithelial neoplasms
    • Wu Y, Soslow RA, Marshall DS, Leitao M, Chen B. Her-2/neu expression and amplification in early stage ovarian surface epithelial neoplasms. Gynecol Oncol 2004; 95: 570-5.
    • (2004) Gynecol Oncol , vol.95 , pp. 570-575
    • Wu, Y.1    Soslow, R.A.2    Marshall, D.S.3    Leitao, M.4    Chen, B.5
  • 34
    • 33646374432 scopus 로고    scopus 로고
    • Cyclin E expression is correlated with tumor progression and predicts a poor prognosis in patients with ovarian carcinoma
    • Rosen DG, Yang G, Deavers MT, et al. Cyclin E expression is correlated with tumor progression and predicts a poor prognosis in patients with ovarian carcinoma. Cancer 2006; 106: 1925-32.
    • (2006) Cancer , vol.106 , pp. 1925-1932
    • Rosen, D.G.1    Yang, G.2    Deavers, M.T.3
  • 35
    • 0034126944 scopus 로고    scopus 로고
    • Gene expression profiles of human endometrial cancer samples using a cDNA-expression array technique: Assessment of an analysis method
    • Smid-Koopman E, Blok LJ, Chadha-Ajwani S, et al. Gene expression profiles of human endometrial cancer samples using a cDNA-expression array technique: assessment of an analysis method. Br J Cancer 2000; 83: 246-51.
    • (2000) Br J Cancer , vol.83 , pp. 246-251
    • Smid-Koopman, E.1    Blok, L.J.2    Chadha-Ajwani, S.3
  • 36
    • 0141619357 scopus 로고    scopus 로고
    • Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas
    • Moreno-Bueno G, Sanchez-Estevez C, Cassia R, et al. Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas. Cancer Res 2003; 63: 5697-702.
    • (2003) Cancer Res , vol.63 , pp. 5697-5702
    • Moreno-Bueno, G.1    Sanchez-Estevez, C.2    Cassia, R.3
  • 37
    • 4644222599 scopus 로고    scopus 로고
    • Distinctive gene expression profiles by cDNA microarrays in endometrioid and serous carcinomas of the endometrium
    • Cao QJ, Belbin T, Socci N, et al. Distinctive gene expression profiles by cDNA microarrays in endometrioid and serous carcinomas of the endometrium. Int J Gynecol Pathol 2004; 23: 321-9.
    • (2004) Int J Gynecol Pathol , vol.23 , pp. 321-329
    • Cao, Q.J.1    Belbin, T.2    Socci, N.3
  • 38
    • 20044364352 scopus 로고    scopus 로고
    • Replicative MCM7 protein as a proliferation marker in endometrial carcinoma: A tissue microarray and clinicopathological analysis
    • Li SS, Xue WC, Khoo US, et al. Replicative MCM7 protein as a proliferation marker in endometrial carcinoma: a tissue microarray and clinicopathological analysis. Histopathology 2005; 46: 307-13.
    • (2005) Histopathology , vol.46 , pp. 307-313
    • Li, S.S.1    Xue, W.C.2    Khoo, U.S.3
  • 39
    • 20044396533 scopus 로고    scopus 로고
    • Promoter methylation and differential expression of pi-class glutathione S-transferase in endometrial carcinoma
    • Chan QK, Khoo US, Chan KY, et al. Promoter methylation and differential expression of pi-class glutathione S-transferase in endometrial carcinoma. J Mol Diagn 2005; 7: 8-16.
    • (2005) J Mol Diagn , vol.7 , pp. 8-16
    • Chan, Q.K.1    Khoo, U.S.2    Chan, K.Y.3
  • 40
    • 0242439284 scopus 로고    scopus 로고
    • Tissue microarray immunohistochemical expression analysis of mismatch repair (hMLH1 and hMSH2 genes) in endometrial carcinoma and atypical endometrial hyperplasia: Relationship with microsatellite instability
    • Hardisson D, Moreno-Bueno G, Sanchez L, et al. Tissue microarray immunohistochemical expression analysis of mismatch repair (hMLH1 and hMSH2 genes) in endometrial carcinoma and atypical endometrial hyperplasia: relationship with microsatellite instability. Mod Pathol 2003; 16: 1148-58.
    • (2003) Mod Pathol , vol.16 , pp. 1148-1158
    • Hardisson, D.1    Moreno-Bueno, G.2    Sanchez, L.3
  • 41
    • 3543085071 scopus 로고    scopus 로고
    • Wilms Tumor Gene (WT1) and p53 expression in endometrial carcinomas: A study of 130 cases using a tissue microarray
    • Dupont J, Wang X, Marshall DS, et al. Wilms Tumor Gene (WT1) and p53 expression in endometrial carcinomas: a study of 130 cases using a tissue microarray. Gynecol Oncol 2004; 94: 449-55.
    • (2004) Gynecol Oncol , vol.94 , pp. 449-455
    • Dupont, J.1    Wang, X.2    Marshall, D.S.3
  • 42
    • 2142760943 scopus 로고    scopus 로고
    • Prognostic impact of alterations in P-cadherin expression and related cell adhesion markers in endometrial cancer
    • Stefansson IM, Salvesen HB, Akslen LA. Prognostic impact of alterations in P-cadherin expression and related cell adhesion markers in endometrial cancer. J Clin Oncol 2004; 22: 1242-52.
    • (2004) J Clin Oncol , vol.22 , pp. 1242-1252
    • Stefansson, I.M.1    Salvesen, H.B.2    Akslen, L.A.3
  • 43
    • 12344336774 scopus 로고    scopus 로고
    • Expression of cancer-testis antigens in endometrial carcinomas using a tissue microarray
    • Chitale DA, Jungbluth AA, Marshall DS, et al. Expression of cancer-testis antigens in endometrial carcinomas using a tissue microarray. Mod Pathol 2005; 18: 119-26.
    • (2005) Mod Pathol , vol.18 , pp. 119-126
    • Chitale, D.A.1    Jungbluth, A.A.2    Marshall, D.S.3
  • 44
    • 9744257018 scopus 로고    scopus 로고
    • Abnormalities in the NF-kappaB family and related proteins in endometrial carcinoma
    • Pallares J, Martinez-Guitarte JL, Dolcet X, et al. Abnormalities in the NF-kappaB family and related proteins in endometrial carcinoma. J Pathol 2004; 204: 569-77.
    • (2004) J Pathol , vol.204 , pp. 569-577
    • Pallares, J.1    Martinez-Guitarte, J.L.2    Dolcet, X.3
  • 45
    • 33744828734 scopus 로고    scopus 로고
    • HER-2 is an independent prognostic factor in endometrial cancer: Association with outcome in a large cohort of surgically staged patients
    • Morrison C, Zanagnolo V, Ramirez N, et al. HER-2 is an independent prognostic factor in endometrial cancer: association with outcome in a large cohort of surgically staged patients. J Clin Oncol 2006; 24: 2376-85.
    • (2006) J Clin Oncol , vol.24 , pp. 2376-2385
    • Morrison, C.1    Zanagnolo, V.2    Ramirez, N.3
  • 46
    • 0032407544 scopus 로고    scopus 로고
    • Profiling of differentially expressed genes in human primary cervical cancer by complementary DNA expression array
    • Shim C, Zhang W, Rhee CH, Lee JH. Profiling of differentially expressed genes in human primary cervical cancer by complementary DNA expression array. Clin Cancer Res 1998; 4: 3045-50.
    • (1998) Clin Cancer Res , vol.4 , pp. 3045-3050
    • Shim, C.1    Zhang, W.2    Rhee, C.H.3    Lee, J.H.4
  • 47
    • 9944262049 scopus 로고    scopus 로고
    • Comparison of gene expression in squamous cell carcinoma and adenocarcinoma of the uterine cervix
    • Contag SA, Gostout BS, Clayton AC, et al. Comparison of gene expression in squamous cell carcinoma and adenocarcinoma of the uterine cervix. Gynecol Oncol 2004; 95: 610-7.
    • (2004) Gynecol Oncol , vol.95 , pp. 610-617
    • Contag, S.A.1    Gostout, B.S.2    Clayton, A.C.3
  • 48
    • 33646504879 scopus 로고    scopus 로고
    • Molecular characterization of adenocarcinoma and squamous carcinoma of the uterine cervix using microarray analysis of gene expression
    • Chao A, Wang TH, Lee YS, et al. Molecular characterization of adenocarcinoma and squamous carcinoma of the uterine cervix using microarray analysis of gene expression. Int J Cancer 2006; 119: 91-8.
    • (2006) Int J Cancer , vol.119 , pp. 91-98
    • Chao, A.1    Wang, T.H.2    Lee, Y.S.3
  • 49
    • 25444435694 scopus 로고    scopus 로고
    • Gene expression profile of cervical tissue compared to exfoliated cells: Impact on biomarker discovery
    • Steinau M, Lee DR, Rajeevan MS, et al. Gene expression profile of cervical tissue compared to exfoliated cells: impact on biomarker discovery. BMC Genomics 2005; 6: 64.
    • (2005) BMC Genomics , vol.6 , pp. 64
    • Steinau, M.1    Lee, D.R.2    Rajeevan, M.S.3
  • 50
    • 0037353968 scopus 로고    scopus 로고
    • Immunoprofile of cervical and endometrial adenocarcinomas using a tissue microarray
    • Alkushi A, Irving J, Hsu F, et al. Immunoprofile of cervical and endometrial adenocarcinomas using a tissue microarray. Virchows Arch 2003; 442: 271-7.
    • (2003) Virchows Arch , vol.442 , pp. 271-277
    • Alkushi, A.1    Irving, J.2    Hsu, F.3
  • 51
    • 33646561555 scopus 로고    scopus 로고
    • Ovarian cancer: Homeobox genes, autocrine/paracrine growth, and kinase signaling
    • Hennessy BT, Mills GB. Ovarian cancer: homeobox genes, autocrine/paracrine growth, and kinase signaling. Int J Biochem Cell Biol 2006; 38: 1450-6.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 1450-1456
    • Hennessy, B.T.1    Mills, G.B.2
  • 52
    • 1242339608 scopus 로고    scopus 로고
    • See HT, Kavanagh JJ, Hu W, Bast RC. Targeted therapy for epithelial ovarian cancer: current status and future prospects. Int J Gynecol Cancer 2003; 13: 701-34.
    • See HT, Kavanagh JJ, Hu W, Bast RC. Targeted therapy for epithelial ovarian cancer: current status and future prospects. Int J Gynecol Cancer 2003; 13: 701-34.
  • 53
    • 33645907542 scopus 로고    scopus 로고
    • Prognostic, predictive and therapeutic implications of HER2 in invasive epithelial ovarian cancer
    • Serrano-Olvera A, Duenas-Gonzalez A, Gallardo-Rincon D, et al. Prognostic, predictive and therapeutic implications of HER2 in invasive epithelial ovarian cancer. Cancer Treat Rev 2006; 32: 180-90.
    • (2006) Cancer Treat Rev , vol.32 , pp. 180-190
    • Serrano-Olvera, A.1    Duenas-Gonzalez, A.2    Gallardo-Rincon, D.3
  • 54
    • 0041629450 scopus 로고    scopus 로고
    • Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
    • Mendelsohn J, Baselga J. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 2003; 21: 2787-99.
    • (2003) J Clin Oncol , vol.21 , pp. 2787-2799
    • Mendelsohn, J.1    Baselga, J.2
  • 55
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995; 19: 183-232.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 56
    • 0029964448 scopus 로고    scopus 로고
    • Expression of cell regulatory proteins in ovarian borderline tumors
    • van Haaften-Day C, Russell P, Boyer CM, et al. Expression of cell regulatory proteins in ovarian borderline tumors. Cancer 1996; 77: 2092-98.
    • (1996) Cancer , vol.77 , pp. 2092-2098
    • van Haaften-Day, C.1    Russell, P.2    Boyer, C.M.3
  • 57
    • 22944491515 scopus 로고    scopus 로고
    • Clinical potential of inhibitors of survival pathways and activators of apoptotic pathways in treatment of cervical cancer: Changing the apoptotic balance
    • Hougardy BM, Maduro JH, van der Zee AG, Willemse PH, de Jong S, de Vries EG. Clinical potential of inhibitors of survival pathways and activators of apoptotic pathways in treatment of cervical cancer: changing the apoptotic balance. Lancet Oncol 2005; 6: 589-98.
    • (2005) Lancet Oncol , vol.6 , pp. 589-598
    • Hougardy, B.M.1    Maduro, J.H.2    van der Zee, A.G.3    Willemse, P.H.4    de Jong, S.5    de Vries, E.G.6
  • 58
    • 0028610516 scopus 로고
    • Expression of c-erbB-2, c-myc, and c-ras oncoproteins, insulin-like growth factor receptor I, and epidermal growth factor receptor in ovarian carcinoma
    • van Dam PA, Vergote IB, Lowe DG, et al. Expression of c-erbB-2, c-myc, and c-ras oncoproteins, insulin-like growth factor receptor I, and epidermal growth factor receptor in ovarian carcinoma. J Clin Pathol 1994; 47: 914-9.
    • (1994) J Clin Pathol , vol.47 , pp. 914-919
    • van Dam, P.A.1    Vergote, I.B.2    Lowe, D.G.3
  • 59
    • 0028927113 scopus 로고
    • Overexpression of c-erbB-2 in epithelial ovarian cancer. Prognostic value and relationship with response to chemotherapy
    • Felip E, Del Campo JM, Rubio D, et al. Overexpression of c-erbB-2 in epithelial ovarian cancer. Prognostic value and relationship with response to chemotherapy. Cancer 1995; 75: 2147-52.
    • (1995) Cancer , vol.75 , pp. 2147-2152
    • Felip, E.1    Del Campo, J.M.2    Rubio, D.3
  • 61
    • 0032952571 scopus 로고    scopus 로고
    • p53, c-erbB2, and PCNA status in benign, proliferative and malignant ovarian surface epithelial neoplasms: A study of 75 cases
    • Anreder MB, Freeman SM, Merogi A, Halabi S, Marrogi AJ. p53, c-erbB2, and PCNA status in benign, proliferative and malignant ovarian surface epithelial neoplasms: a study of 75 cases. Arch Pathol Lab Med 1999; 123: 310-6.
    • (1999) Arch Pathol Lab Med , vol.123 , pp. 310-316
    • Anreder, M.B.1    Freeman, S.M.2    Merogi, A.3    Halabi, S.4    Marrogi, A.J.5
  • 62
    • 0033061635 scopus 로고    scopus 로고
    • HER-2/neu oncogene amplification by fluorescence in situ hybridization in epithelial tumors of the ovary
    • Ross JS, Yang F, Kallakury BV, et al. HER-2/neu oncogene amplification by fluorescence in situ hybridization in epithelial tumors of the ovary. Am J Clin Pathol 1999; 111: 311-6.
    • (1999) Am J Clin Pathol , vol.111 , pp. 311-316
    • Ross, J.S.1    Yang, F.2    Kallakury, B.V.3
  • 63
    • 0037440042 scopus 로고    scopus 로고
    • Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the Gynecologic Oncology Group
    • Bookman MA, Darcy KM, Clarke-Pearson D, et al. Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology Group. J Clin Oncol 2003; 21: 283-90.
    • (2003) J Clin Oncol , vol.21 , pp. 283-290
    • Bookman, M.A.1    Darcy, K.M.2    Clarke-Pearson, D.3
  • 64
    • 20244378677 scopus 로고    scopus 로고
    • Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer
    • Agus DB, Gordon MS, Taylor C, et al. Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer. J Clin Oncol 2005; 23: 2534-43.
    • (2005) J Clin Oncol , vol.23 , pp. 2534-2543
    • Agus, D.B.1    Gordon, M.S.2    Taylor, C.3
  • 66
    • 0035476866 scopus 로고    scopus 로고
    • The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: Potential therapy for cancer
    • Rusnak DW, Affleck K, Cockerill SG, et al. The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer. Cancer Res 2001; 61: 7196-203.
    • (2001) Cancer Res , vol.61 , pp. 7196-7203
    • Rusnak, D.W.1    Affleck, K.2    Cockerill, S.G.3
  • 67
    • 0028032256 scopus 로고
    • Correlation of C-myc and HER-2/neu amplification and expression with histopathologic variables in uterine corpus cancer
    • Monk BJ, Chapman JA, Johnson GA, et al. Correlation of C-myc and HER-2/neu amplification and expression with histopathologic variables in uterine corpus cancer. Am J Obstet Gynecol 1994; 171: 1193-8.
    • (1994) Am J Obstet Gynecol , vol.171 , pp. 1193-1198
    • Monk, B.J.1    Chapman, J.A.2    Johnson, G.A.3
  • 68
    • 0028226459 scopus 로고
    • Expression of EGFR, HER-2/neu, P53, and PCNA in endometrioid, serous papillary, and clear cell endometrial adenocarcinomas
    • Khalifa MA, Mannel RS, Haraway SD, Walker J, Min KW. Expression of EGFR, HER-2/neu, P53, and PCNA in endometrioid, serous papillary, and clear cell endometrial adenocarcinomas. Gynecol Oncol 1994; 53: 84-92.
    • (1994) Gynecol Oncol , vol.53 , pp. 84-92
    • Khalifa, M.A.1    Mannel, R.S.2    Haraway, S.D.3    Walker, J.4    Min, K.W.5
  • 69
    • 0028985949 scopus 로고
    • Amplification and expression of the c-erbB-2 oncogene in normal, hyperplastic, and malignant endometria
    • Czerwenka K, Lu Y, Heuss F. Amplification and expression of the c-erbB-2 oncogene in normal, hyperplastic, and malignant endometria. Int J Gynecol Pathol 1995; 14: 98-106.
    • (1995) Int J Gynecol Pathol , vol.14 , pp. 98-106
    • Czerwenka, K.1    Lu, Y.2    Heuss, F.3
  • 70
    • 0028021340 scopus 로고
    • Uterine papillary serous adenocarcinoma. A 10-case study of p53 and c-erbB-2 expression and DNA content
    • Prat J, Oliva E, Lerma E, Vaquero M, Matias-Guiu X. Uterine papillary serous adenocarcinoma. A 10-case study of p53 and c-erbB-2 expression and DNA content. Cancer 1994; 74: 1778-83.
    • (1994) Cancer , vol.74 , pp. 1778-1783
    • Prat, J.1    Oliva, E.2    Lerma, E.3    Vaquero, M.4    Matias-Guiu, X.5
  • 71
    • 0031670618 scopus 로고    scopus 로고
    • Correlation of proliferation indices, apoptosis, and related oncogene expression (bcl-2 and c-erbB-2) and p53 in proliferative, hyperplastic, and malignant endometrium
    • Ioffe OB, Papadimitriou JC, Drachenberg CB. Correlation of proliferation indices, apoptosis, and related oncogene expression (bcl-2 and c-erbB-2) and p53 in proliferative, hyperplastic, and malignant endometrium. Hum Pathol 1998; 29: 1150-9.
    • (1998) Hum Pathol , vol.29 , pp. 1150-1159
    • Ioffe, O.B.1    Papadimitriou, J.C.2    Drachenberg, C.B.3
  • 72
    • 21044450500 scopus 로고    scopus 로고
    • Gene expression fingerprint of uterine serous papillary carcinoma: Identification of novel molecular markers for uterine serous cancer diagnosis and therapy
    • Santin AD, Zhan F, Cane S, et al. Gene expression fingerprint of uterine serous papillary carcinoma: identification of novel molecular markers for uterine serous cancer diagnosis and therapy. Br J Cancer 2005; 92: 1561-73.
    • (2005) Br J Cancer , vol.92 , pp. 1561-1573
    • Santin, A.D.1    Zhan, F.2    Cane, S.3
  • 73
    • 20044367622 scopus 로고    scopus 로고
    • Racial differences in the overexpression of epidermal growth factor type II receptor (HER2/ neu): A major prognostic indicator in uterine serous papillary cancer
    • Santin AD, Bellone S, Siegel ER, et al. Racial differences in the overexpression of epidermal growth factor type II receptor (HER2/ neu): a major prognostic indicator in uterine serous papillary cancer. Am J Obstet Gynecol 2005; 192: 813-8.
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 813-818
    • Santin, A.D.1    Bellone, S.2    Siegel, E.R.3
  • 74
    • 4143100453 scopus 로고    scopus 로고
    • Her-2/neu overexpression and amplification in uterine papillary serous carcinoma
    • Slomovitz BM, Broaddus RR, Burke TW, et al. Her-2/neu overexpression and amplification in uterine papillary serous carcinoma. J Clin Oncol 2004; 22: 3126-32.
    • (2004) J Clin Oncol , vol.22 , pp. 3126-3132
    • Slomovitz, B.M.1    Broaddus, R.R.2    Burke, T.W.3
  • 75
    • 0028919705 scopus 로고
    • HER-2/neu, p53, and DNA analyses as prognosticators for survival in endometrial carcinoma
    • Pisani AL, Barbuto DA, Chen D, et al. HER-2/neu, p53, and DNA analyses as prognosticators for survival in endometrial carcinoma. Obstet Gynecol 1995; 85: 729-34.
    • (1995) Obstet Gynecol , vol.85 , pp. 729-734
    • Pisani, A.L.1    Barbuto, D.A.2    Chen, D.3
  • 76
    • 0028947475 scopus 로고
    • Detection of c-erbB-2/neu and fibroblast growth factor-3/INT-2 but not epidermal growth factor receptor gene amplification in endometrial cancer by differential polymerase chain reaction
    • Esteller M, Garcia A, Martinez I, Palones JM, Cabero A, Reventos J. Detection of c-erbB-2/neu and fibroblast growth factor-3/INT-2 but not epidermal growth factor receptor gene amplification in endometrial cancer by differential polymerase chain reaction. Cancer 1995; 75: 2139-46.
    • (1995) Cancer , vol.75 , pp. 2139-2146
    • Esteller, M.1    Garcia, A.2    Martinez, I.3    Palones, J.M.4    Cabero, A.5    Reventos, J.6
  • 77
    • 0028034150 scopus 로고
    • Expression of p53, transforming growth factor alpha, epidermal growth factor receptor, and c-erbB-2 in endometrial carcinoma and correlation with survival and known predictors of survival
    • Reinartz JJ, George E, Lindgren BR, Niehans GA. Expression of p53, transforming growth factor alpha, epidermal growth factor receptor, and c-erbB-2 in endometrial carcinoma and correlation with survival and known predictors of survival. Hum Pathol 1994; 25: 1075-83.
    • (1994) Hum Pathol , vol.25 , pp. 1075-1083
    • Reinartz, J.J.1    George, E.2    Lindgren, B.R.3    Niehans, G.A.4
  • 78
    • 0028099536 scopus 로고
    • Immunocytochemical study of epidermal growth factor receptor, transforming growth factor alpha, and 'squamous differentiation' in human endometrial carcinoma
    • Santini D, Ceccarelli C, Martinelli GN, et al. Immunocytochemical study of epidermal growth factor receptor, transforming growth factor alpha, and 'squamous differentiation' in human endometrial carcinoma. Hum Pathol 1994; 25: 1319-23.
    • (1994) Hum Pathol , vol.25 , pp. 1319-1323
    • Santini, D.1    Ceccarelli, C.2    Martinelli, G.N.3
  • 79
    • 33646934663 scopus 로고    scopus 로고
    • Old and new perspectives in the pharmacological treatment of advanced or recurrent endometrial cancer: Hormonal therapy, chemotherapy and molecularly targeted therapies
    • Gadducci A, Cosio S, Genazzani AR. Old and new perspectives in the pharmacological treatment of advanced or recurrent endometrial cancer: Hormonal therapy, chemotherapy and molecularly targeted therapies. Crit Rev Oncol Hematol 2006; 58: 242-56.
    • (2006) Crit Rev Oncol Hematol , vol.58 , pp. 242-256
    • Gadducci, A.1    Cosio, S.2    Genazzani, A.R.3
  • 80
    • 0032884699 scopus 로고    scopus 로고
    • Proto-oncogenes and p53 protein expression in normal cervical stratified squamous epithelium and cervical intra-epithelial neoplasia
    • Ngan HY, Liu SS, Yu H, Liu KL, Cheung AN. Proto-oncogenes and p53 protein expression in normal cervical stratified squamous epithelium and cervical intra-epithelial neoplasia. Eur J Cancer 1999; 35: 1546-50.
    • (1999) Eur J Cancer , vol.35 , pp. 1546-1550
    • Ngan, H.Y.1    Liu, S.S.2    Yu, H.3    Liu, K.L.4    Cheung, A.N.5
  • 81
    • 0033042754 scopus 로고    scopus 로고
    • Oncogene alterations in carcinomas of the uterine cervix: Overexpression of the epidermal growth factor receptor is associated with poor prognosis
    • Kersemaekers AM, Fleuren GJ, Kenter GG, et al. Oncogene alterations in carcinomas of the uterine cervix: overexpression of the epidermal growth factor receptor is associated with poor prognosis. Clin Cancer Res 1999; 5: 577-86.
    • (1999) Clin Cancer Res , vol.5 , pp. 577-586
    • Kersemaekers, A.M.1    Fleuren, G.J.2    Kenter, G.G.3
  • 82
    • 0032950875 scopus 로고    scopus 로고
    • Frequent amplification of C-erbB2 (HER-2/Neu) oncogene in cervical carcinoma as detected by non-fluorescence in situ hybridization technique on paraffin sections
    • Sharma A, Pratap M, Sawhney VM, et al. Frequent amplification of C-erbB2 (HER-2/Neu) oncogene in cervical carcinoma as detected by non-fluorescence in situ hybridization technique on paraffin sections. Oncology 1999; 56: 83-7.
    • (1999) Oncology , vol.56 , pp. 83-87
    • Sharma, A.1    Pratap, M.2    Sawhney, V.M.3
  • 83
    • 0033019433 scopus 로고    scopus 로고
    • The significance of Erb-b2 immunostaining in cervical cancer
    • Nevin J, Laing D, Kaye P, et al. The significance of Erb-b2 immunostaining in cervical cancer. Gynecol Oncol 1999; 73: 354-8.
    • (1999) Gynecol Oncol , vol.73 , pp. 354-358
    • Nevin, J.1    Laing, D.2    Kaye, P.3
  • 84
    • 0031016541 scopus 로고    scopus 로고
    • Correlation of cervical carcinoma c-erb B-2 oncogene with cell proliferation parameters in patients treated with radiation therapy for cervical carcinoma
    • Nakano T, Oka K, Ishikawa A, Morita S. Correlation of cervical carcinoma c-erb B-2 oncogene with cell proliferation parameters in patients treated with radiation therapy for cervical carcinoma. Cancer 1997; 79: 513-20.
    • (1997) Cancer , vol.79 , pp. 513-520
    • Nakano, T.1    Oka, K.2    Ishikawa, A.3    Morita, S.4
  • 85
    • 0032907639 scopus 로고    scopus 로고
    • Prognostic significance of c-erbB-2 protein expression in carcinoma of the cervix treated with radiotherapy
    • Nishioka T, West CM, Gupta N, et al. Prognostic significance of c-erbB-2 protein expression in carcinoma of the cervix treated with radiotherapy. J Cancer Res Clin Oncol 1999; 125: 96-100.
    • (1999) J Cancer Res Clin Oncol , vol.125 , pp. 96-100
    • Nishioka, T.1    West, C.M.2    Gupta, N.3
  • 86
    • 0029016521 scopus 로고
    • c-erbB-3 proto-oncogene expression in uterine cervical carcinoma
    • Hunt CR, Hale RJ, Armstrong C, et al. c-erbB-3 proto-oncogene expression in uterine cervical carcinoma. Int J Gynecol Cancer 1995; 5: 282-5.
    • (1995) Int J Gynecol Cancer , vol.5 , pp. 282-285
    • Hunt, C.R.1    Hale, R.J.2    Armstrong, C.3
  • 87
    • 27144469023 scopus 로고    scopus 로고
    • Correlation between human epidermal growth factor receptor family (EGFR, HER2, HER3, HER4), phosphorylated Akt (P-Akt), and clinical outcomes after radiation therapy in carcinoma of the cervix
    • Lee CM, Shrieve DC, Zempolich KA, et al. Correlation between human epidermal growth factor receptor family (EGFR, HER2, HER3, HER4), phosphorylated Akt (P-Akt), and clinical outcomes after radiation therapy in carcinoma of the cervix. Gynecol Oncol 2005; 99: 415-21.
    • (2005) Gynecol Oncol , vol.99 , pp. 415-421
    • Lee, C.M.1    Shrieve, D.C.2    Zempolich, K.A.3
  • 88
    • 13144302944 scopus 로고    scopus 로고
    • HER2 expression in cervical cancer as a potential therapeutic target
    • Chavez-Blanco A, Perez-Sanchez V, Gonzalez-Fierro A, et al. HER2 expression in cervical cancer as a potential therapeutic target. BMC Cancer 2004; 4: 59.
    • (2004) BMC Cancer , vol.4 , pp. 59
    • Chavez-Blanco, A.1    Perez-Sanchez, V.2    Gonzalez-Fierro, A.3
  • 89
    • 0042456000 scopus 로고    scopus 로고
    • Tumour-proliferative fraction and growth factor expression as markers of tumour response to radiotherapy in cancer of the uterine cervix
    • Pillai MR, Jayaprakash PG, Nair MK. Tumour-proliferative fraction and growth factor expression as markers of tumour response to radiotherapy in cancer of the uterine cervix. J Cancer Res Clin Oncol 1998; 124: 456-61.
    • (1998) J Cancer Res Clin Oncol , vol.124 , pp. 456-461
    • Pillai, M.R.1    Jayaprakash, P.G.2    Nair, M.K.3
  • 90
    • 0035479052 scopus 로고    scopus 로고
    • C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability
    • Nasu S, Ang KK, Fan Z, Milas L. C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability. Int J Radiat Oncol Biol Phys 2001; 51: 474-7.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 474-477
    • Nasu, S.1    Ang, K.K.2    Fan, Z.3    Milas, L.4
  • 91
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997; 275: 1943-7.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3
  • 92
    • 0000227612 scopus 로고    scopus 로고
    • PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis
    • Besson A, Robbins SM, Yong VW. PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis. Eur J Biochem 1999; 263: 605-11.
    • (1999) Eur J Biochem , vol.263 , pp. 605-611
    • Besson, A.1    Robbins, S.M.2    Yong, V.W.3
  • 93
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Di Cristofano A, Pandolfi PP. The multiple roles of PTEN in tumor suppression. Cell 2000; 100: 387-90.
    • (2000) Cell , vol.100 , pp. 387-390
    • Di Cristofano, A.1    Pandolfi, P.P.2
  • 94
    • 0032475861 scopus 로고    scopus 로고
    • Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
    • Stambolic V, Suzuki A, de la Pompa JL, et al. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 1998; 95: 29-39.
    • (1998) Cell , vol.95 , pp. 29-39
    • Stambolic, V.1    Suzuki, A.2    de la Pompa, J.L.3
  • 96
    • 0038274803 scopus 로고    scopus 로고
    • Loss of PTEN expression followed by Akt phosphorylation is a poor prognostic factor for patients with endometrial cancer
    • Terakawa N, Kanamori Y, Yoshida S. Loss of PTEN expression followed by Akt phosphorylation is a poor prognostic factor for patients with endometrial cancer. Endocr Relat Cancer 2003; 10: 203-8.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 203-208
    • Terakawa, N.1    Kanamori, Y.2    Yoshida, S.3
  • 97
    • 4344602002 scopus 로고    scopus 로고
    • The biology and clinical relevance of the PTEN tumor suppressor pathway
    • Sansal I, Sellers WR. The biology and clinical relevance of the PTEN tumor suppressor pathway. J Clin Oncol 2004; 22: 2954-63.
    • (2004) J Clin Oncol , vol.22 , pp. 2954-2963
    • Sansal, I.1    Sellers, W.R.2
  • 98
    • 0041802820 scopus 로고    scopus 로고
    • Targeting mTOR signaling for cancer therapy
    • Huang S, Houghton PJ. Targeting mTOR signaling for cancer therapy. Curr Opin Pharmacol 2003; 3: 371-7.
    • (2003) Curr Opin Pharmacol , vol.3 , pp. 371-377
    • Huang, S.1    Houghton, P.J.2
  • 99
    • 0032485937 scopus 로고    scopus 로고
    • Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability
    • Hashemolhosseini S, Nagamine Y, Morley SJ, et al. Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability. J Biol Chem 1998; 273: 14424-9.
    • (1998) J Biol Chem , vol.273 , pp. 14424-14429
    • Hashemolhosseini, S.1    Nagamine, Y.2    Morley, S.J.3
  • 100
    • 0032590011 scopus 로고    scopus 로고
    • PIK3CA is implicated as an oncogene in ovarian cancer
    • Shayesteh L, Lu Y, Kuo WL, et al. PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet 1999; 21: 99-102.
    • (1999) Nat Genet , vol.21 , pp. 99-102
    • Shayesteh, L.1    Lu, Y.2    Kuo, W.L.3
  • 101
    • 7444250290 scopus 로고    scopus 로고
    • Mutation of the PIK3CA gene in ovarian and breast cancer
    • Campbell IG, Russell SE, Choong DY, et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 2004; 64: 7678-81.
    • (2004) Cancer Res , vol.64 , pp. 7678-7681
    • Campbell, I.G.1    Russell, S.E.2    Choong, D.Y.3
  • 103
    • 0034616634 scopus 로고    scopus 로고
    • Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers
    • Mutter GL, Lin MC, Fitzgerald JT, et al. Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers. J Natl Cancer Inst 2000; 92: 924-30.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 924-930
    • Mutter, G.L.1    Lin, M.C.2    Fitzgerald, J.T.3
  • 104
    • 0036428714 scopus 로고    scopus 로고
    • Alteration of PTEN expression in endometrial carcinoma is associated with down-regulation of cyclin-dependent kinase inhibitor, p27
    • An HJ, Lee YH, Cho NH, et al. Alteration of PTEN expression in endometrial carcinoma is associated with down-regulation of cyclin-dependent kinase inhibitor, p27. Histopathology 2002; 41: 437-45.
    • (2002) Histopathology , vol.41 , pp. 437-445
    • An, H.J.1    Lee, Y.H.2    Cho, N.H.3
  • 105
    • 2342483301 scopus 로고    scopus 로고
    • Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells
    • Zhou C, Gehrig PA, Whang YE, Boggess JF. Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells. Mol Cancer Ther 2003; 2: 789-95.
    • (2003) Mol Cancer Ther , vol.2 , pp. 789-795
    • Zhou, C.1    Gehrig, P.A.2    Whang, Y.E.3    Boggess, J.F.4
  • 106
    • 33646944014 scopus 로고    scopus 로고
    • mTOR inhibition as a potential treatment for progesterone refractory endometrial hyperplasia
    • Soliman P, Schmeler KM, Broaddus RR, et al. mTOR inhibition as a potential treatment for progesterone refractory endometrial hyperplasia. Proc Am Soc Clin Oncol 2005; 23: 5080.
    • (2005) Proc Am Soc Clin Oncol , vol.23 , pp. 5080
    • Soliman, P.1    Schmeler, K.M.2    Broaddus, R.R.3
  • 107
    • 27744539151 scopus 로고    scopus 로고
    • Tumor angiogenesis and molecular target therapy in ovarian carcinomas
    • Ueda M, Terai Y, Kanda K, et al. Tumor angiogenesis and molecular target therapy in ovarian carcinomas. Hum Cell 2005; 18: 1-16.
    • (2005) Hum Cell , vol.18 , pp. 1-16
    • Ueda, M.1    Terai, Y.2    Kanda, K.3
  • 108
    • 18344380440 scopus 로고    scopus 로고
    • Ovarian cancer metastasis: Integrating insights from disparate model organisms
    • Naora H, Montell DJ. Ovarian cancer metastasis: integrating insights from disparate model organisms. Nat Rev Cancer 2005; 5: 355-66.
    • (2005) Nat Rev Cancer , vol.5 , pp. 355-366
    • Naora, H.1    Montell, D.J.2
  • 109
    • 2442663092 scopus 로고    scopus 로고
    • Activated signal transducer and activator of transcription (STAT) 3: Localization in focal adhesions and function in ovarian cancer cell motility
    • Silver DL, Naora H, Liu J, Cheng W, Montell DJ. Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility. Cancer Res 2004; 64: 3550-8.
    • (2004) Cancer Res , vol.64 , pp. 3550-3558
    • Silver, D.L.1    Naora, H.2    Liu, J.3    Cheng, W.4    Montell, D.J.5
  • 110
    • 0041673349 scopus 로고    scopus 로고
    • Human papillomavirus reporting: Impact on Bethesda cytology reports
    • Raab SS. Human papillomavirus reporting: impact on Bethesda cytology reports. Arch Pathol Lab Med 2003; 127: 969-72.
    • (2003) Arch Pathol Lab Med , vol.127 , pp. 969-972
    • Raab, S.S.1
  • 113
    • 0026516503 scopus 로고
    • Human papillomavirus infection of the cervix: Relative risk associations of 15 common anogenital types
    • Lorincz AT, Reid R, Jenson AB, et al. Human papillomavirus infection of the cervix: relative risk associations of 15 common anogenital types. Obstet Gynecol 1992; 79: 328-37.
    • (1992) Obstet Gynecol , vol.79 , pp. 328-337
    • Lorincz, A.T.1    Reid, R.2    Jenson, A.B.3
  • 114
    • 0031608295 scopus 로고    scopus 로고
    • Richart RM, Masood S, Syrjanen KJ, et al. Human papillomavirus. International Academy of Cytology Task Force summary. Diagnostic Cytology Towards the 21st Century: An International Expert Conference and Tutorial. Acta Cytol 1998; 42: 50-8.
    • Richart RM, Masood S, Syrjanen KJ, et al. Human papillomavirus. International Academy of Cytology Task Force summary. Diagnostic Cytology Towards the 21st Century: An International Expert Conference and Tutorial. Acta Cytol 1998; 42: 50-8.
  • 115
    • 0029041842 scopus 로고
    • Prevalence of human papillomavirus in cervical cancer: A worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group
    • Bosch FX, Manos MM, Munoz N, et al. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group. J Natl Cancer Inst 1995; 87: 796-802.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 796-802
    • Bosch, F.X.1    Manos, M.M.2    Munoz, N.3
  • 116
    • 0032840918 scopus 로고    scopus 로고
    • Human papilloma-virus is a necessary cause of invasive cervical cancer worldwide
    • Walboomers JM, Jacobs MV, Manos MM, et al. Human papilloma-virus is a necessary cause of invasive cervical cancer worldwide. J Pathol 1999; 189: 12-9.
    • (1999) J Pathol , vol.189 , pp. 12-19
    • Walboomers, J.M.1    Jacobs, M.V.2    Manos, M.M.3
  • 117
    • 0031888717 scopus 로고    scopus 로고
    • Aetiology, pathogenesis, and pathology of cervical neoplasia
    • Arends MJ, Buckley CH, Wells M. Aetiology, pathogenesis, and pathology of cervical neoplasia. J Clin Pathol 1998; 51: 96-103.
    • (1998) J Clin Pathol , vol.51 , pp. 96-103
    • Arends, M.J.1    Buckley, C.H.2    Wells, M.3
  • 118
    • 8444249386 scopus 로고    scopus 로고
    • Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: A randomised controlled trial
    • Harper DM, Franco EL, Wheeler C, et al. Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: a randomised controlled trial. Lancet 2004; 364: 1757-65.
    • (2004) Lancet , vol.364 , pp. 1757-1765
    • Harper, D.M.1    Franco, E.L.2    Wheeler, C.3
  • 119
    • 33646058566 scopus 로고    scopus 로고
    • Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: Follow-up from a randomised control trial
    • Harper DM, Franco EL, Wheeler CM, et al. Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trial. Lancet 2006; 367: 1247-55.
    • (2006) Lancet , vol.367 , pp. 1247-1255
    • Harper, D.M.1    Franco, E.L.2    Wheeler, C.M.3
  • 120
    • 33747877038 scopus 로고    scopus 로고
    • : Current findings from prophylactic HPV vaccine trials
    • Suppl 3
    • Koutsky LA, Harper DM. Chapter 13: Current findings from prophylactic HPV vaccine trials. Vaccine 2006; 24 (Suppl 3): S114-21.
    • (2006) Vaccine
    • Koutsky, L.A.1    Harper, D.M.2
  • 121
    • 20944448032 scopus 로고    scopus 로고
    • Villa LL, Costa RL, Petta CA, et al. Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial. Lancet Oncol 2005; 6: 271-8.
    • Villa LL, Costa RL, Petta CA, et al. Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial. Lancet Oncol 2005; 6: 271-8.
  • 122
    • 0031779875 scopus 로고    scopus 로고
    • HPV typing by in situ hybridization on cervical cytologic smears with ASCUS
    • Autillo-Touati A, Joannes M, d'Ercole C, et al. HPV typing by in situ hybridization on cervical cytologic smears with ASCUS. Acta Cytol 1998; 42: 631-8.
    • (1998) Acta Cytol , vol.42 , pp. 631-638
    • Autillo-Touati, A.1    Joannes, M.2    d'Ercole, C.3
  • 123
    • 0031735079 scopus 로고    scopus 로고
    • Generation of type-specific probes for the detection of single-copy human papillomavirus by a novel in situ hybridization method
    • Huang CC, Qiu JT, Kashima ML, Kurman RJ, Wu TC. Generation of type-specific probes for the detection of single-copy human papillomavirus by a novel in situ hybridization method. Mod Pathol 1998; 11: 971-7.
    • (1998) Mod Pathol , vol.11 , pp. 971-977
    • Huang, C.C.1    Qiu, J.T.2    Kashima, M.L.3    Kurman, R.J.4    Wu, T.C.5
  • 124
    • 0036273196 scopus 로고    scopus 로고
    • Telomerase assay and HPV 16/18 typing as adjunct to conventional cytological cervical cancer screening
    • Ngan HY, Cheung AN, Liu SS, Liu KL, Tsao SW. Telomerase assay and HPV 16/18 typing as adjunct to conventional cytological cervical cancer screening. Tumour Biol 2002; 23: 87-92.
    • (2002) Tumour Biol , vol.23 , pp. 87-92
    • Ngan, H.Y.1    Cheung, A.N.2    Liu, S.S.3    Liu, K.L.4    Tsao, S.W.5
  • 125
    • 33748570853 scopus 로고    scopus 로고
    • Semi-quantitative fluorescent PCR analysis identifies PRKAA1 on chromosome 5 as a potential candidate cancer gene of cervical cancer
    • Huang FY, Chiu PM, Tam KF, et al. Semi-quantitative fluorescent PCR analysis identifies PRKAA1 on chromosome 5 as a potential candidate cancer gene of cervical cancer. Gynecol Oncol 2006; 103: 219-25.
    • (2006) Gynecol Oncol , vol.103 , pp. 219-225
    • Huang, F.Y.1    Chiu, P.M.2    Tam, K.F.3
  • 126
    • 0033105716 scopus 로고    scopus 로고
    • Abnormal expression or mutation of TP53 and HPV in vulvar cancer
    • Ngan HY, Cheung AN, Liu SS, Yip PS, Tsao SW. Abnormal expression or mutation of TP53 and HPV in vulvar cancer. Eur J Cancer 1999; 35: 481-4.
    • (1999) Eur J Cancer , vol.35 , pp. 481-484
    • Ngan, H.Y.1    Cheung, A.N.2    Liu, S.S.3    Yip, P.S.4    Tsao, S.W.5
  • 127
    • 0030793675 scopus 로고    scopus 로고
    • Comparison of the hybrid capture tube test and PCR for detection of human papillomavirus DNA in cervical specimens
    • Cope JU, Hildesheim A, Schiffman MH, et al. Comparison of the hybrid capture tube test and PCR for detection of human papillomavirus DNA in cervical specimens. J Clin Microbiol 1997; 35: 2262-5.
    • (1997) J Clin Microbiol , vol.35 , pp. 2262-2265
    • Cope, J.U.1    Hildesheim, A.2    Schiffman, M.H.3
  • 128
    • 0344699343 scopus 로고    scopus 로고
    • Comparative evaluation of first- and second-generation digene hybrid capture assays for detection of human papillomaviruses associated with high or intermediate risk for cervical cancer
    • Poljak M, Brencic A, Seme K, Vince A, Marin IJ. Comparative evaluation of first- and second-generation digene hybrid capture assays for detection of human papillomaviruses associated with high or intermediate risk for cervical cancer. J Clin Microbiol 1999; 37: 796-7.
    • (1999) J Clin Microbiol , vol.37 , pp. 796-797
    • Poljak, M.1    Brencic, A.2    Seme, K.3    Vince, A.4    Marin, I.J.5
  • 129
    • 0031719639 scopus 로고    scopus 로고
    • Comparison of PCR-and hybrid capture-based human papillomavirus detection systems using multiple cervical specimen collection strategies
    • Peyton CL, Schiffman M, Lorincz AT, et al. Comparison of PCR-and hybrid capture-based human papillomavirus detection systems using multiple cervical specimen collection strategies. J Clin Microbiol 1998; 36: 3248-54.
    • (1998) J Clin Microbiol , vol.36 , pp. 3248-3254
    • Peyton, C.L.1    Schiffman, M.2    Lorincz, A.T.3
  • 130
    • 0028814969 scopus 로고
    • Accuracy and interlaboratory reliability of human papillomavirus DNA testing by hybrid capture
    • Schiffman MH, Kiviat NB, Burk RD, et al. Accuracy and interlaboratory reliability of human papillomavirus DNA testing by hybrid capture. J Clin Microbiol 1995; 33: 545-50.
    • (1995) J Clin Microbiol , vol.33 , pp. 545-550
    • Schiffman, M.H.1    Kiviat, N.B.2    Burk, R.D.3
  • 131
    • 0031585924 scopus 로고    scopus 로고
    • Cervical specimens collected in liquid buffer are suitable for both cytologic screening and ancillary human papillomavirus testing
    • Sherman ME, Schiffman MH, Lorincz AT, et al. Cervical specimens collected in liquid buffer are suitable for both cytologic screening and ancillary human papillomavirus testing. Cancer 1997; 81: 89-97.
    • (1997) Cancer , vol.81 , pp. 89-97
    • Sherman, M.E.1    Schiffman, M.H.2    Lorincz, A.T.3
  • 132
    • 33750936268 scopus 로고    scopus 로고
    • Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: Comparison of HPV risk group to cytology and histology
    • Castle PE, Sadorra M, Garcia F, Holladay EB, Kornegay J. Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: comparison of HPV risk group to cytology and histology. J Clin Microbiol 2006; 44: 3915-7.
    • (2006) J Clin Microbiol , vol.44 , pp. 3915-3917
    • Castle, P.E.1    Sadorra, M.2    Garcia, F.3    Holladay, E.B.4    Kornegay, J.5
  • 133
    • 33646579137 scopus 로고    scopus 로고
    • Human papillomavirus genotyping using a modified linear array detection protocol
    • Stevens MP, Garland SM, Tabrizi SN. Human papillomavirus genotyping using a modified linear array detection protocol. J Virol Methods 2006; 135: 124-6.
    • (2006) J Virol Methods , vol.135 , pp. 124-126
    • Stevens, M.P.1    Garland, S.M.2    Tabrizi, S.N.3
  • 134
    • 24644483289 scopus 로고    scopus 로고
    • Persistent high risk HPV infection associated with development of cervical neoplasia in a prospective population study
    • Cuschieri KS, Cubie HA, Whitley MW, et al. Persistent high risk HPV infection associated with development of cervical neoplasia in a prospective population study. J Clin Pathol 2005; 58: 946-50.
    • (2005) J Clin Pathol , vol.58 , pp. 946-950
    • Cuschieri, K.S.1    Cubie, H.A.2    Whitley, M.W.3
  • 135
    • 29144443541 scopus 로고    scopus 로고
    • Development and evaluation of a highly sensitive human papillomavirus genotyping DNA chip
    • Kim KH, Yoon MS, Na YJ, et al. Development and evaluation of a highly sensitive human papillomavirus genotyping DNA chip. Gynecol Oncol 2006; 100: 38-43.
    • (2006) Gynecol Oncol , vol.100 , pp. 38-43
    • Kim, K.H.1    Yoon, M.S.2    Na, Y.J.3
  • 136
    • 33745157895 scopus 로고    scopus 로고
    • Development of a sensitive and specific assay combining multiplex PCR and DNA microarray primer extension to detect high-risk mucosal human papillomavirus types
    • Gheit T, Landi S, Gemignani F, et al. Development of a sensitive and specific assay combining multiplex PCR and DNA microarray primer extension to detect high-risk mucosal human papillomavirus types. J Clin Microbiol 2006; 44: 2025-31.
    • (2006) J Clin Microbiol , vol.44 , pp. 2025-2031
    • Gheit, T.1    Landi, S.2    Gemignani, F.3
  • 137
    • 1842831217 scopus 로고    scopus 로고
    • Atypical squamous cells of undetermined significance on cervical smears: Follow-up study of an Asian screening population
    • Cheung AN, Szeto EF, Ng KM, et al. Atypical squamous cells of undetermined significance on cervical smears: follow-up study of an Asian screening population. Cancer 2004; 102: 74-80.
    • (2004) Cancer , vol.102 , pp. 74-80
    • Cheung, A.N.1    Szeto, E.F.2    Ng, K.M.3
  • 138
    • 0031833452 scopus 로고    scopus 로고
    • Where's the high-grade cervical neoplasia? The importance of minimally abnormal Papanicolaou diagnoses
    • Kinney WK, Manos MM, Hurley LB, Ransley JE. Where's the high-grade cervical neoplasia? The importance of minimally abnormal Papanicolaou diagnoses. Obstet Gynecol 1998; 91: 973-6.
    • (1998) Obstet Gynecol , vol.91 , pp. 973-976
    • Kinney, W.K.1    Manos, M.M.2    Hurley, L.B.3    Ransley, J.E.4
  • 139
    • 0033526316 scopus 로고    scopus 로고
    • Identifying women with cervical neoplasia: Using human papillomavirus DNA testing for equivocal Papanicolaou results
    • Manos MM, Kinney WK, Hurley LB, et al. Identifying women with cervical neoplasia: using human papillomavirus DNA testing for equivocal Papanicolaou results. JAMA 1999; 281: 1605-10.
    • (1999) JAMA , vol.281 , pp. 1605-1610
    • Manos, M.M.1    Kinney, W.K.2    Hurley, L.B.3
  • 140
    • 0032783712 scopus 로고    scopus 로고
    • Atypical glandular cells of undetermined significance (AGUS): Cytopathologic features, histopathologic results, and human papillomavirus DNA detection
    • Ronnett BM, Manos MM, Ransley JE, et al. Atypical glandular cells of undetermined significance (AGUS): cytopathologic features, histopathologic results, and human papillomavirus DNA detection. Hum Pathol 1999; 30: 816-25.
    • (1999) Hum Pathol , vol.30 , pp. 816-825
    • Ronnett, B.M.1    Manos, M.M.2    Ransley, J.E.3
  • 141
    • 0027468157 scopus 로고
    • Use of semi-quantitative PCR for human papillomavirus DNA type 16 to identify women with high grade cervical disease in a population presenting with a mildly dyskaryotic smear report
    • Bavin PJ, Giles JA, Deery A, et al. Use of semi-quantitative PCR for human papillomavirus DNA type 16 to identify women with high grade cervical disease in a population presenting with a mildly dyskaryotic smear report. Br J Cancer 1993; 67: 602-5.
    • (1993) Br J Cancer , vol.67 , pp. 602-605
    • Bavin, P.J.1    Giles, J.A.2    Deery, A.3
  • 142
    • 0031727348 scopus 로고    scopus 로고
    • Detection of human papillomavirus in Papanicolaou smears: Correlation with pathologic findings and clinical outcome
    • Nuovo GJ. Detection of human papillomavirus in Papanicolaou smears: correlation with pathologic findings and clinical outcome. Diagn Mol Pathol 1998; 7: 158-63.
    • (1998) Diagn Mol Pathol , vol.7 , pp. 158-163
    • Nuovo, G.J.1
  • 144
    • 0028924317 scopus 로고
    • Human papillomavirus testing by hybrid capture appears to be useful in triaging women with a cytologic diagnosis of atypical squamous cells of undetermined significance
    • Cox JT, Lorincz AT, Schiffman MH, et al. Human papillomavirus testing by hybrid capture appears to be useful in triaging women with a cytologic diagnosis of atypical squamous cells of undetermined significance. Am J Obstet Gynecol 1995; 172: 946-54.
    • (1995) Am J Obstet Gynecol , vol.172 , pp. 946-954
    • Cox, J.T.1    Lorincz, A.T.2    Schiffman, M.H.3
  • 145
    • 0033526367 scopus 로고    scopus 로고
    • Evaluating the role of HPV testing for women with equivocal Papanicolaou test findings
    • Cox JT. Evaluating the role of HPV testing for women with equivocal Papanicolaou test findings. JAMA 1999; 281: 1645-7.
    • (1999) JAMA , vol.281 , pp. 1645-1647
    • Cox, J.T.1
  • 146
    • 0031806962 scopus 로고    scopus 로고
    • Reflex human papillomavirus deoxyribonucleic acid testing in women with abnormal Papanicolaou smears
    • Wright TC, Jr, Lorincz A, Ferris DG, et al. Reflex human papillomavirus deoxyribonucleic acid testing in women with abnormal Papanicolaou smears. Am J Obstet Gynecol 1998; 178: 962-6.
    • (1998) Am J Obstet Gynecol , vol.178 , pp. 962-966
    • Wright Jr, T.C.1    Lorincz, A.2    Ferris, D.G.3
  • 147
    • 33847212110 scopus 로고    scopus 로고
    • Department of Health and Human Services, Division of STD Prevention, Prevention of genital HPV Infection and Sequelae: Report of an External Consultants' Meeting. Altanta: Centres for Disease Control and Prevention (CDC), 1999. http://www.cdc.gov/nchstp/dstd/Reports_Publications/99HPVReport.htm
    • Department of Health and Human Services, Division of STD Prevention, Prevention of genital HPV Infection and Sequelae: Report of an External Consultants' Meeting. Altanta: Centres for Disease Control and Prevention (CDC), 1999. http://www.cdc.gov/nchstp/dstd/Reports_Publications/99HPVReport.htm
  • 148
    • 0030008084 scopus 로고    scopus 로고
    • Can papilloma virus testing be used to improve cervical cancer screening?
    • Jenkins D, Sherlaw-Johnson C, Gallivan S. Can papilloma virus testing be used to improve cervical cancer screening? Int J Cancer 1996; 65: 768-773.
    • (1996) Int J Cancer , vol.65 , pp. 768-773
    • Jenkins, D.1    Sherlaw-Johnson, C.2    Gallivan, S.3
  • 149
    • 0030010030 scopus 로고    scopus 로고
    • Screening for cervical intraepithelial neoplasia grade 2/3: Validity of cytologic study, cervicography, and human papillomavirus detection
    • Schneider A, Zahm DM, Kirchmayr R, Schneider VL. Screening for cervical intraepithelial neoplasia grade 2/3: validity of cytologic study, cervicography, and human papillomavirus detection. Am J Obstet Gynecol 1996; 174: 1534-41.
    • (1996) Am J Obstet Gynecol , vol.174 , pp. 1534-1541
    • Schneider, A.1    Zahm, D.M.2    Kirchmayr, R.3    Schneider, V.L.4
  • 150
    • 0030794704 scopus 로고    scopus 로고
    • Present evidence on the value of HPV testing for cervical cancer screening: A model-based exploration of the (cost-)effectiveness
    • van Ballegooijen M, van den Akker-van Marle ME, Warmerdam PG, et al. Present evidence on the value of HPV testing for cervical cancer screening: a model-based exploration of the (cost-)effectiveness. Br J Cancer 1997; 76: 651-7.
    • (1997) Br J Cancer , vol.76 , pp. 651-657
    • van Ballegooijen, M.1    van den Akker-van Marle, M.E.2    Warmerdam, P.G.3
  • 151
    • 0032864654 scopus 로고    scopus 로고
    • HPV testing in primary screening of older women
    • Cuzick J, Beverley E, Ho L, et al. HPV testing in primary screening of older women. Br J Cancer 1999; 81: 554-8.
    • (1999) Br J Cancer , vol.81 , pp. 554-558
    • Cuzick, J.1    Beverley, E.2    Ho, L.3
  • 152
    • 10744221527 scopus 로고    scopus 로고
    • Management of women who test positive for high-risk types of human papillomavirus: The HART study
    • Cuzick J, Szarewski A, Cubie H, et al. Management of women who test positive for high-risk types of human papillomavirus: the HART study. Lancet 2003; 362: 1871-6.
    • (2003) Lancet , vol.362 , pp. 1871-1876
    • Cuzick, J.1    Szarewski, A.2    Cubie, H.3
  • 153
    • 33747892271 scopus 로고    scopus 로고
    • : Issues in planning cervical cancer screening in the era of HPV vaccination
    • Suppl 3
    • Franco EL, Cuzick J, Hildesheim A, de Sanjose S. Chapter 20: Issues in planning cervical cancer screening in the era of HPV vaccination. Vaccine 2006; 24 (Suppl 3): S171-7.
    • (2006) Vaccine
    • Franco, E.L.1    Cuzick, J.2    Hildesheim, A.3    de Sanjose, S.4
  • 154
    • 33745267064 scopus 로고    scopus 로고
    • Human papillomavirus testing and liquid-based cytology: Results at recruitment from the new technologies for cervical cancer randomized controlled trial
    • Ronco G, Segnan N, Giorgi-Rossi P, et al. Human papillomavirus testing and liquid-based cytology: results at recruitment from the new technologies for cervical cancer randomized controlled trial. J Natl Cancer Inst 2006; 98: 765-74.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 765-774
    • Ronco, G.1    Segnan, N.2    Giorgi-Rossi, P.3
  • 155
    • 33745278233 scopus 로고    scopus 로고
    • Human papillomavirus testing and liquid-based cytology in primary screening of women younger than 35 years: Results at recruitment for a randomised controlled trial
    • Ronco G, Giorgi-Rossi P, Carozzi F, et al. Human papillomavirus testing and liquid-based cytology in primary screening of women younger than 35 years: results at recruitment for a randomised controlled trial. Lancet Oncol 2006; 7: 547-55.
    • (2006) Lancet Oncol , vol.7 , pp. 547-555
    • Ronco, G.1    Giorgi-Rossi, P.2    Carozzi, F.3
  • 156
    • 84944661248 scopus 로고
    • Interim guidelines for management of abnormal cervical cytology. The 1992 National Cancer Institute Workshop
    • Kurman RJ, Henson DE, Herbst AL, Noller KL, Schiffman MH. Interim guidelines for management of abnormal cervical cytology. The 1992 National Cancer Institute Workshop. JAMA 1994; 271: 1866-9.
    • (1994) JAMA , vol.271 , pp. 1866-1869
    • Kurman, R.J.1    Henson, D.E.2    Herbst, A.L.3    Noller, K.L.4    Schiffman, M.H.5
  • 157
    • 0026738776 scopus 로고
    • A cohort study of the risk of cervical intraepithelial neoplasia grade 2 or 3 in relation to papillomavirus infection
    • Koutsky LA, Holmes KK, Critchlow CW, et al. A cohort study of the risk of cervical intraepithelial neoplasia grade 2 or 3 in relation to papillomavirus infection. N Engl J Med 1992; 327: 1272-8.
    • (1992) N Engl J Med , vol.327 , pp. 1272-1278
    • Koutsky, L.A.1    Holmes, K.K.2    Critchlow, C.W.3
  • 158
    • 0032510076 scopus 로고    scopus 로고
    • Natural history of cervicovaginal papillomavirus infection in young women
    • Ho GY, Bierman R, Beardsley L, Chang CJ, Burk RD. Natural history of cervicovaginal papillomavirus infection in young women. N Engl J Med 1998; 338: 423-8.
    • (1998) N Engl J Med , vol.338 , pp. 423-428
    • Ho, G.Y.1    Bierman, R.2    Beardsley, L.3    Chang, C.J.4    Burk, R.D.5
  • 159
    • 0033519946 scopus 로고    scopus 로고
    • Relation of human papillomavirus status to cervical lesions and consequences for cervical-cancer screening: A prospective study
    • Nobbenhuis MA, Walboomers JM, Helmerhorst TJ, et al. Relation of human papillomavirus status to cervical lesions and consequences for cervical-cancer screening: a prospective study. Lancet 1999; 354: 20-5.
    • (1999) Lancet , vol.354 , pp. 20-25
    • Nobbenhuis, M.A.1    Walboomers, J.M.2    Helmerhorst, T.J.3
  • 160
    • 0029147763 scopus 로고
    • Persistent genital human papillomavirus infection as a risk factor for persistent cervical dysplasia
    • Ho GY, Burk RD, Klein S, et al. Persistent genital human papillomavirus infection as a risk factor for persistent cervical dysplasia. J Natl Cancer Inst 1995; 87: 1365-71.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1365-1371
    • Ho, G.Y.1    Burk, R.D.2    Klein, S.3
  • 161
    • 0031194612 scopus 로고    scopus 로고
    • Human papillomavirus analysis as a prognostic marker following conization of the cervix uteri
    • Chua KL, Hjerpe A. Human papillomavirus analysis as a prognostic marker following conization of the cervix uteri. Gynecol Oncol 1997; 66: 108-13.
    • (1997) Gynecol Oncol , vol.66 , pp. 108-113
    • Chua, K.L.1    Hjerpe, A.2
  • 162
    • 0034936712 scopus 로고    scopus 로고
    • Negative predictive value of human papillomavirus test following conization of the cervix uteri
    • Jain S, Tseng CJ, Horng SG, Soong YK, Pao CC. Negative predictive value of human papillomavirus test following conization of the cervix uteri. Gynecol Oncol 2001; 82: 177-80.
    • (2001) Gynecol Oncol , vol.82 , pp. 177-180
    • Jain, S.1    Tseng, C.J.2    Horng, S.G.3    Soong, Y.K.4    Pao, C.C.5
  • 163
    • 0035056379 scopus 로고    scopus 로고
    • Value of human papillomavirus deoxyribonucleic acid testing after conization in the prediction of residual disease in the subsequent hysterectomy specimen
    • Lin CT, Tseng CJ, Lai CH, et al. Value of human papillomavirus deoxyribonucleic acid testing after conization in the prediction of residual disease in the subsequent hysterectomy specimen. Am J Obstet Gynecol 2001; 184: 940-5.
    • (2001) Am J Obstet Gynecol , vol.184 , pp. 940-945
    • Lin, C.T.1    Tseng, C.J.2    Lai, C.H.3
  • 164
    • 0025337336 scopus 로고
    • Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA
    • Riou G, Favre M, Jeannel D, et al. Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA. Lancet 1990; 335: 1171-4.
    • (1990) Lancet , vol.335 , pp. 1171-1174
    • Riou, G.1    Favre, M.2    Jeannel, D.3
  • 165
    • 0026072287 scopus 로고
    • Increased age and mortality associated with cervical carcinomas negative for human papillomavirus RNA
    • Higgins GD, Davy M, Roder D, Uzelin DM, Phillips GE, Burrell CJ. Increased age and mortality associated with cervical carcinomas negative for human papillomavirus RNA. Lancet 1991; 338: 910-3.
    • (1991) Lancet , vol.338 , pp. 910-913
    • Higgins, G.D.1    Davy, M.2    Roder, D.3    Uzelin, D.M.4    Phillips, G.E.5    Burrell, C.J.6
  • 166
    • 0026524486 scopus 로고
    • Prognostic importance of human papillomavirus type 16 DNA in cervical cancer
    • Girardi F, Fuchs P, Haas J. Prognostic importance of human papillomavirus type 16 DNA in cervical cancer. Cancer 1992; 69: 2502-4.
    • (1992) Cancer , vol.69 , pp. 2502-2504
    • Girardi, F.1    Fuchs, P.2    Haas, J.3
  • 167
    • 0027157874 scopus 로고
    • Human papillomavirus type 18 associates with more advanced cervical neoplasia than human papillomavirus type 16
    • Arends MJ, Donaldson YK, Duvall E, Wyllie AH, Bird CC. Human papillomavirus type 18 associates with more advanced cervical neoplasia than human papillomavirus type 16. Hum Pathol 1993; 24: 432-7.
    • (1993) Hum Pathol , vol.24 , pp. 432-437
    • Arends, M.J.1    Donaldson, Y.K.2    Duvall, E.3    Wyllie, A.H.4    Bird, C.C.5
  • 168
    • 15144355902 scopus 로고    scopus 로고
    • Presence of human papilloma virus DNA in pelvic lymph nodes can predict unexpected recurrence of cervical cancer in patients with histologically negative lymph nodes
    • Kobayashi Y, Yoshinouchi M, Tianqi G, et al. Presence of human papilloma virus DNA in pelvic lymph nodes can predict unexpected recurrence of cervical cancer in patients with histologically negative lymph nodes. Clin Cancer Res 1998; 4: 979-83.
    • (1998) Clin Cancer Res , vol.4 , pp. 979-983
    • Kobayashi, Y.1    Yoshinouchi, M.2    Tianqi, G.3
  • 169
    • 14344258386 scopus 로고    scopus 로고
    • The HPV test in cervical screening: A brave new world?
    • Desai MS, Cubie HA. The HPV test in cervical screening: a brave new world? Cytopathology 2005; 16: 3-6.
    • (2005) Cytopathology , vol.16 , pp. 3-6
    • Desai, M.S.1    Cubie, H.A.2
  • 170
    • 14844356474 scopus 로고    scopus 로고
    • Emerging technology in cervical cancer screening: Status of molecular markers
    • Padilla-Paz LA. Emerging technology in cervical cancer screening: status of molecular markers. Clin Obstet Gynecol 2005; 48: 218-25.
    • (2005) Clin Obstet Gynecol , vol.48 , pp. 218-225
    • Padilla-Paz, L.A.1
  • 171
    • 0029883791 scopus 로고    scopus 로고
    • Immunocytochemical staining on ThinPrep processed smears
    • Leung SW, Bedard YC. Immunocytochemical staining on ThinPrep processed smears. Mod Pathol 1996; 9: 304-6.
    • (1996) Mod Pathol , vol.9 , pp. 304-306
    • Leung, S.W.1    Bedard, Y.C.2
  • 172
    • 0034712008 scopus 로고    scopus 로고
    • Molecular biology in cytopathology: Current applications and future directions
    • Rimm DL. Molecular biology in cytopathology: current applications and future directions. Cancer 2000; 90: 1-9.
    • (2000) Cancer , vol.90 , pp. 1-9
    • Rimm, D.L.1
  • 173
    • 0035286679 scopus 로고    scopus 로고
    • Surrogate biomarkers of HPV infection in cervical neoplasia screening and diagnosis
    • Keating JT, Ince T, Crum CP. Surrogate biomarkers of HPV infection in cervical neoplasia screening and diagnosis. Adv Anat Pathol 2001; 8: 83-92.
    • (2001) Adv Anat Pathol , vol.8 , pp. 83-92
    • Keating, J.T.1    Ince, T.2    Crum, C.P.3
  • 174
    • 0037289732 scopus 로고    scopus 로고
    • p16INK4a is a useful marker for the diagnosis of adenocarcinoma of the cervix uteri and its precursors: An immunohistochemical study with immunocytochemical correlations
    • Negri G, Egarter-Vigl E, Kasal A, et al. p16INK4a is a useful marker for the diagnosis of adenocarcinoma of the cervix uteri and its precursors: an immunohistochemical study with immunocytochemical correlations. Am J Surg Pathol 2003; 27: 187-93.
    • (2003) Am J Surg Pathol , vol.27 , pp. 187-193
    • Negri, G.1    Egarter-Vigl, E.2    Kasal, A.3
  • 175
    • 31844433618 scopus 로고    scopus 로고
    • Immunocytochemistry in liquid-based cervical cytology: Analysis of clinical use following a cross-sectional study
    • Sahebali S, Depuydt CE, Boulet GA, et al. Immunocytochemistry in liquid-based cervical cytology: analysis of clinical use following a cross-sectional study. Int J Cancer 2006; 118: 1254-60.
    • (2006) Int J Cancer , vol.118 , pp. 1254-1260
    • Sahebali, S.1    Depuydt, C.E.2    Boulet, G.A.3
  • 176
    • 3142514396 scopus 로고    scopus 로고
    • Chromosome in situ hybridisation, Ki-67, and telomerase immunocytochemistry in liquid based cervical cytology
    • Cheung AN, Chiu PM, Tsun KL, Khoo US, Leung BS, Ngan HY. Chromosome in situ hybridisation, Ki-67, and telomerase immunocytochemistry in liquid based cervical cytology. J Clin Pathol 2004; 57: 721-7.
    • (2004) J Clin Pathol , vol.57 , pp. 721-727
    • Cheung, A.N.1    Chiu, P.M.2    Tsun, K.L.3    Khoo, U.S.4    Leung, B.S.5    Ngan, H.Y.6
  • 177
    • 1842853122 scopus 로고    scopus 로고
    • Usefulness of liquid-based cytology specimens for the immunocytochemical study of p16 expression and human papillomavirus testing: A comparative study using simultaneously sampled histology materials
    • Yoshida T, Fukuda T, Sano T, Kanuma T, Owada N, Nakajima T. Usefulness of liquid-based cytology specimens for the immunocytochemical study of p16 expression and human papillomavirus testing: a comparative study using simultaneously sampled histology materials. Cancer 2004; 102: 100-8.
    • (2004) Cancer , vol.102 , pp. 100-108
    • Yoshida, T.1    Fukuda, T.2    Sano, T.3    Kanuma, T.4    Owada, N.5    Nakajima, T.6
  • 178
    • 1342263744 scopus 로고    scopus 로고
    • P16INK4a as an adjunct marker in liquid-based cervical cytology
    • Sahebali S, Depuydt CE, Segers K, et al. P16INK4a as an adjunct marker in liquid-based cervical cytology. Int J Cancer 2004; 108: 871-6.
    • (2004) Int J Cancer , vol.108 , pp. 871-876
    • Sahebali, S.1    Depuydt, C.E.2    Segers, K.3
  • 179
    • 0031740497 scopus 로고    scopus 로고
    • Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions
    • Sano T, Oyama T, Kashiwabara K, Fukuda T, Nakajima T. Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions. Am J Pathol 1998; 153: 1741-8.
    • (1998) Am J Pathol , vol.153 , pp. 1741-1748
    • Sano, T.1    Oyama, T.2    Kashiwabara, K.3    Fukuda, T.4    Nakajima, T.5
  • 180
    • 0034962509 scopus 로고    scopus 로고
    • Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia
    • Keating JT, Cviko A, Riethdorf S, et al. Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia. Am J Surg Pathol 2001; 25: 884-91.
    • (2001) Am J Surg Pathol , vol.25 , pp. 884-891
    • Keating, J.T.1    Cviko, A.2    Riethdorf, S.3
  • 181
    • 0035871985 scopus 로고    scopus 로고
    • Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri
    • Klaes R, Friedrich T, Spitkovsky D, et al. Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Int J Cancer 2001; 92: 276-84.
    • (2001) Int J Cancer , vol.92 , pp. 276-284
    • Klaes, R.1    Friedrich, T.2    Spitkovsky, D.3
  • 182
    • 0037770031 scopus 로고    scopus 로고
    • p16(INK4a) expression correlates with degree of cervical neoplasia: A comparison with Ki-67 expression and detection of high-risk HPV types
    • Agoff SN, Lin P, Morihara J, Mao C, Kiviat NB, Koutsky LA. p16(INK4a) expression correlates with degree of cervical neoplasia: a comparison with Ki-67 expression and detection of high-risk HPV types. Mod Pathol 2003; 16: 665-73.
    • (2003) Mod Pathol , vol.16 , pp. 665-673
    • Agoff, S.N.1    Lin, P.2    Morihara, J.3    Mao, C.4    Kiviat, N.B.5    Koutsky, L.A.6
  • 183
    • 3042851635 scopus 로고    scopus 로고
    • Evaluation of p16INK4a and pRb expression in cervical squamous and glandular neoplasia
    • Tringler B, Gup CJ, Singh M, et al. Evaluation of p16INK4a and pRb expression in cervical squamous and glandular neoplasia. Hum Pathol 2004; 35: 689-96.
    • (2004) Hum Pathol , vol.35 , pp. 689-696
    • Tringler, B.1    Gup, C.J.2    Singh, M.3
  • 184
    • 0037207502 scopus 로고    scopus 로고
    • p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrep smears
    • Murphy N, Ring M, Killalea AG, et al. p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrep smears. J Clin Pathol 2003; 56: 56-63.
    • (2003) J Clin Pathol , vol.56 , pp. 56-63
    • Murphy, N.1    Ring, M.2    Killalea, A.G.3
  • 185
    • 33748128513 scopus 로고    scopus 로고
    • p16INK4a immunoexpression: Surrogate marker of high-risk HPV and high-grade cervical intraepithelial neoplasia
    • Kalof AN, Cooper K. p16INK4a immunoexpression: surrogate marker of high-risk HPV and high-grade cervical intraepithelial neoplasia. Adv Anat Pathol 2006; 13: 190-4.
    • (2006) Adv Anat Pathol , vol.13 , pp. 190-194
    • Kalof, A.N.1    Cooper, K.2
  • 186
    • 23944496041 scopus 로고    scopus 로고
    • Trichomonas vaginalis P16 Immunoreactivity in cervicovaginal Pap tests: A diagnostic pitfall
    • Pantanowitz L, Florence RR, Goulart RA, Otis CN. Trichomonas vaginalis P16 Immunoreactivity in cervicovaginal Pap tests: a diagnostic pitfall. Diagn Cytopathol 2005; 33: 210-3.
    • (2005) Diagn Cytopathol , vol.33 , pp. 210-213
    • Pantanowitz, L.1    Florence, R.R.2    Goulart, R.A.3    Otis, C.N.4
  • 187
    • 1642494668 scopus 로고    scopus 로고
    • Distinction of endocervical and endometrial adenocarcinomas: Immunohistochemical p16 expression correlated with human papillomavirus (HPV) DNA detection
    • Ansari-Lari MA, Staebler A, Zaino RJ, Shah KV, Ronnett BM. Distinction of endocervical and endometrial adenocarcinomas: immunohistochemical p16 expression correlated with human papillomavirus (HPV) DNA detection. Am J Surg Pathol 2004; 28: 160-7.
    • (2004) Am J Surg Pathol , vol.28 , pp. 160-167
    • Ansari-Lari, M.A.1    Staebler, A.2    Zaino, R.J.3    Shah, K.V.4    Ronnett, B.M.5
  • 188
    • 0037531418 scopus 로고    scopus 로고
    • p16 immunoreactivity may assist in the distinction between endometrial and endocervical adenocarcinoma
    • McCluggage WG, Jenkins D. p16 immunoreactivity may assist in the distinction between endometrial and endocervical adenocarcinoma. Int J Gynecol Pathol 2003; 22: 231-5.
    • (2003) Int J Gynecol Pathol , vol.22 , pp. 231-235
    • McCluggage, W.G.1    Jenkins, D.2
  • 189
    • 0034929515 scopus 로고    scopus 로고
    • DNA methylation: An alternative pathway to cancer
    • Wajed SA, Laird PW, DeMeester TR. DNA methylation: an alternative pathway to cancer. Ann Surg 2001; 234: 10-20.
    • (2001) Ann Surg , vol.234 , pp. 10-20
    • Wajed, S.A.1    Laird, P.W.2    DeMeester, T.R.3
  • 191
    • 0032587282 scopus 로고    scopus 로고
    • Methylation of p16INK4A in primary gynecologic malignancy
    • Wong YF, Chung TK, Cheung TH, et al. Methylation of p16INK4A in primary gynecologic malignancy. Cancer Lett 1999; 136: 231-5.
    • (1999) Cancer Lett , vol.136 , pp. 231-235
    • Wong, Y.F.1    Chung, T.K.2    Cheung, T.H.3
  • 192
    • 8744242129 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in hydatidiform mole and choriocarcinoma
    • Xue WC, Chan KY, Feng HC, et al. Promoter hypermethylation of multiple genes in hydatidiform mole and choriocarcinoma. J Mol Diagn 2004; 6: 326-34.
    • (2004) J Mol Diagn , vol.6 , pp. 326-334
    • Xue, W.C.1    Chan, K.Y.2    Feng, H.C.3
  • 193
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004; 429: 457-63.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 194
    • 13844320790 scopus 로고    scopus 로고
    • GSTP1 hypermethylation as a molecular marker in the diagnosis of prostatic cancer: Is there a correlation with clinical stage, Gleason grade, PSA value or age?
    • Bastian PJ, Ellinger J, Schmidt D, et al. GSTP1 hypermethylation as a molecular marker in the diagnosis of prostatic cancer: is there a correlation with clinical stage, Gleason grade, PSA value or age? Eur J Med Res 2004; 9: 523-7.
    • (2004) Eur J Med Res , vol.9 , pp. 523-527
    • Bastian, P.J.1    Ellinger, J.2    Schmidt, D.3
  • 195
    • 5144220196 scopus 로고    scopus 로고
    • Molecular detection of prostate cancer: A role for GSTP1 hypermethylation
    • discussion 669
    • Henrique R, Jeronimo C. Molecular detection of prostate cancer: a role for GSTP1 hypermethylation. Eur Urol 2004; 46: 660-9; discussion 669.
    • (2004) Eur Urol , vol.46 , pp. 660-669
    • Henrique, R.1    Jeronimo, C.2
  • 196
    • 0343621494 scopus 로고    scopus 로고
    • Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
    • Costello JF, Fruhwald MC, Smiraglia DJ, et al. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 2000; 24: 132-8.
    • (2000) Nat Genet , vol.24 , pp. 132-138
    • Costello, J.F.1    Fruhwald, M.C.2    Smiraglia, D.J.3
  • 198
    • 14644396228 scopus 로고    scopus 로고
    • Detection and interpretation of altered methylation patterns in cancer cells
    • Ushijima T. Detection and interpretation of altered methylation patterns in cancer cells. Nat Rev Cancer 2005; 5: 223-31.
    • (2005) Nat Rev Cancer , vol.5 , pp. 223-231
    • Ushijima, T.1
  • 199
    • 0037355974 scopus 로고    scopus 로고
    • Sensitive detection of DNA methylation
    • Cottrell SE, Laird PW. Sensitive detection of DNA methylation. Ann NY Acad Sci 2003; 983: 120-30.
    • (2003) Ann NY Acad Sci , vol.983 , pp. 120-130
    • Cottrell, S.E.1    Laird, P.W.2
  • 200
    • 0038576158 scopus 로고    scopus 로고
    • The power and the promise of DNA methylation markers
    • Laird PW. The power and the promise of DNA methylation markers. Nat Rev Cancer 2003; 3: 253-66.
    • (2003) Nat Rev Cancer , vol.3 , pp. 253-266
    • Laird, P.W.1
  • 201
    • 0037099625 scopus 로고    scopus 로고
    • Epigenetic factors controlling the BRCA1 and BRCA2 genes in sporadic ovarian cancer
    • Chan KY, Ozcelik H, Cheung AN, Ngan HY, Khoo US. Epigenetic factors controlling the BRCA1 and BRCA2 genes in sporadic ovarian cancer. Cancer Res 2002; 62: 4151-6.
    • (2002) Cancer Res , vol.62 , pp. 4151-4156
    • Chan, K.Y.1    Ozcelik, H.2    Cheung, A.N.3    Ngan, H.Y.4    Khoo, U.S.5
  • 202
    • 17844395211 scopus 로고    scopus 로고
    • Epigenetic and genetic alterations of p33ING1b in ovarian cancer
    • Shen DH, Chan KY, Khoo US, et al. Epigenetic and genetic alterations of p33ING1b in ovarian cancer. Carcinogenesis 2005; 26: 855-63.
    • (2005) Carcinogenesis , vol.26 , pp. 855-863
    • Shen, D.H.1    Chan, K.Y.2    Khoo, U.S.3
  • 203
    • 0034904625 scopus 로고    scopus 로고
    • DNA methylation and ovarian cancer. I. Analysis of CpG island hypermethylation in human ovarian cancer using differential methylation hybridization
    • Ahluwalia A, Yan P, Hurteau JA, et al. DNA methylation and ovarian cancer. I. Analysis of CpG island hypermethylation in human ovarian cancer using differential methylation hybridization. Gynecol Oncol 2001; 82: 261-8.
    • (2001) Gynecol Oncol , vol.82 , pp. 261-268
    • Ahluwalia, A.1    Yan, P.2    Hurteau, J.A.3
  • 204
    • 0033970096 scopus 로고    scopus 로고
    • Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer
    • Bianco T, Chenevix-Trench G, Walsh DC, Cooper JE, Dobrovic A. Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer. Carcinogenesis 2000; 21: 147-51.
    • (2000) Carcinogenesis , vol.21 , pp. 147-151
    • Bianco, T.1    Chenevix-Trench, G.2    Walsh, D.C.3    Cooper, J.E.4    Dobrovic, A.5
  • 205
    • 0035099160 scopus 로고    scopus 로고
    • Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes
    • Strathdee G, Appleton K, Illand M, et al. Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes. Am J Pathol 2001; 158: 1121-7.
    • (2001) Am J Pathol , vol.158 , pp. 1121-1127
    • Strathdee, G.1    Appleton, K.2    Illand, M.3
  • 206
    • 23044466227 scopus 로고    scopus 로고
    • Promoter hypermethylation profile of ovarian epithelial neoplasms
    • Makarla PB, Saboorian MH, Ashfaq R, et al. Promoter hypermethylation profile of ovarian epithelial neoplasms. Clin Cancer Res 2005; 11: 5365-9.
    • (2005) Clin Cancer Res , vol.11 , pp. 5365-5369
    • Makarla, P.B.1    Saboorian, M.H.2    Ashfaq, R.3
  • 207
    • 33646725688 scopus 로고    scopus 로고
    • Prognostic DNA methylation biomarkers in ovarian cancer
    • Wei SH, Balch C, Paik HH, et al. Prognostic DNA methylation biomarkers in ovarian cancer. Clin Cancer Res 2006; 12: 2788-94.
    • (2006) Clin Cancer Res , vol.12 , pp. 2788-2794
    • Wei, S.H.1    Balch, C.2    Paik, H.H.3
  • 208
    • 0035992386 scopus 로고    scopus 로고
    • Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers
    • Wei SH, Chen CM, Strathdee G, et al. Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers. Clin Cancer Res 2002; 8: 2246-52.
    • (2002) Clin Cancer Res , vol.8 , pp. 2246-2252
    • Wei, S.H.1    Chen, C.M.2    Strathdee, G.3
  • 209
    • 12344267687 scopus 로고    scopus 로고
    • Gene expression signature with independent prognostic significance in epithelial ovarian cancer
    • Spentzos D, Levine DA, Ramoni MF, et al. Gene expression signature with independent prognostic significance in epithelial ovarian cancer. J Clin Oncol 2004; 22: 4700-10.
    • (2004) J Clin Oncol , vol.22 , pp. 4700-4710
    • Spentzos, D.1    Levine, D.A.2    Ramoni, M.F.3
  • 210
    • 20444457518 scopus 로고    scopus 로고
    • Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
    • Glinsky GV, Berezovska O, Glinskii AB. Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest 2005; 115: 1503-21.
    • (2005) J Clin Invest , vol.115 , pp. 1503-1521
    • Glinsky, G.V.1    Berezovska, O.2    Glinskii, A.B.3
  • 211
    • 0032706744 scopus 로고    scopus 로고
    • hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis
    • Esteller M, Catasus L, Matias-Guiu X, et al. hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis. Am J Pathol 1999; 155: 1767-72.
    • (1999) Am J Pathol , vol.155 , pp. 1767-1772
    • Esteller, M.1    Catasus, L.2    Matias-Guiu, X.3
  • 212
    • 0035754225 scopus 로고    scopus 로고
    • New molecular tumor markers for endometrial cancer
    • Numa F, Umayahara K, Suehiro Y, et al. New molecular tumor markers for endometrial cancer. Hum Cell 2001; 14: 272-4.
    • (2001) Hum Cell , vol.14 , pp. 272-274
    • Numa, F.1    Umayahara, K.2    Suehiro, Y.3
  • 213
    • 0031041908 scopus 로고    scopus 로고
    • Association of IGF2 and H19 imprinting with choriocarcinoma development
    • Arima T, Matsuda T, Takagi N, Wake N. Association of IGF2 and H19 imprinting with choriocarcinoma development. Cancer Genet Cytogenet 1997; 93: 39-47.
    • (1997) Cancer Genet Cytogenet , vol.93 , pp. 39-47
    • Arima, T.1    Matsuda, T.2    Takagi, N.3    Wake, N.4
  • 214
    • 0142154308 scopus 로고    scopus 로고
    • Suppression of gap junctional intercellular communication via 5′ CpG island methylation in promoter region of E-cadherin gene in endometrial cancer cells
    • Nishimura M, Saito T, Yamasaki H, Kudo R. Suppression of gap junctional intercellular communication via 5′ CpG island methylation in promoter region of E-cadherin gene in endometrial cancer cells. Carcinogenesis 2003; 24: 1615-23.
    • (2003) Carcinogenesis , vol.24 , pp. 1615-1623
    • Nishimura, M.1    Saito, T.2    Yamasaki, H.3    Kudo, R.4
  • 215
    • 0033990501 scopus 로고    scopus 로고
    • Comparative genomic hybridization studies in hydatidiform moles and choriocarcinoma: Amplification of 7q21-q31 and loss of 8p12-p21 in choriocarcinoma
    • Ahmed MN, Kim K, Haddad B, Berchuck A, Qumsiyeh MB. Comparative genomic hybridization studies in hydatidiform moles and choriocarcinoma: amplification of 7q21-q31 and loss of 8p12-p21 in choriocarcinoma. Cancer Genet Cytogenet 2000; 116: 10-5.
    • (2000) Cancer Genet Cytogenet , vol.116 , pp. 10-15
    • Ahmed, M.N.1    Kim, K.2    Haddad, B.3    Berchuck, A.4    Qumsiyeh, M.B.5
  • 216
    • 33747463915 scopus 로고    scopus 로고
    • RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma
    • Kang S, Lee JM, Jeon ES, et al. RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma. Int J Cancer 2006; 119: 1316-21.
    • (2006) Int J Cancer , vol.119 , pp. 1316-1321
    • Kang, S.1    Lee, J.M.2    Jeon, E.S.3
  • 217
    • 0034772724 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix
    • Dong SM, Kim HS, Rha SH, Sidransky D. Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix. Clin Cancer Res 2001; 7: 1982-6.
    • (2001) Clin Cancer Res , vol.7 , pp. 1982-1986
    • Dong, S.M.1    Kim, H.S.2    Rha, S.H.3    Sidransky, D.4
  • 218
    • 0034899399 scopus 로고    scopus 로고
    • Aberrant methylation during cervical carcinogenesis
    • Virmani AK, Muller C, Rathi A, et al. Aberrant methylation during cervical carcinogenesis. Clin Cancer Res 2001; 7: 584-9.
    • (2001) Clin Cancer Res , vol.7 , pp. 584-589
    • Virmani, A.K.1    Muller, C.2    Rathi, A.3
  • 219
    • 0033607147 scopus 로고    scopus 로고
    • In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis
    • Nuovo GJ, Plaia TW, Belinsky SA, et al. In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis. Proc Natl Acad Sci USA 1999; 96: 12754-9.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12754-12759
    • Nuovo, G.J.1    Plaia, T.W.2    Belinsky, S.A.3
  • 220
    • 1242281346 scopus 로고    scopus 로고
    • Frequent promoter methylation of CDH1, DAPK, RARB, and HIC1 genes in carcinoma of cervix uteri: Its relationship to clinical outcome
    • Narayan G, Arias-Pulido H, Koul S, et al. Frequent promoter methylation of CDH1, DAPK, RARB, and HIC1 genes in carcinoma of cervix uteri: its relationship to clinical outcome. Mol Cancer 2003; 2: 24.
    • (2003) Mol Cancer , vol.2 , pp. 24
    • Narayan, G.1    Arias-Pulido, H.2    Koul, S.3
  • 221
    • 1942508904 scopus 로고    scopus 로고
    • Detection of hypermethylated genes in tumor and plasma of cervical cancer patients
    • Yang HJ, Liu VW, Wang Y, et al. Detection of hypermethylated genes in tumor and plasma of cervical cancer patients. Gynecol Oncol 2004; 93: 435-40.
    • (2004) Gynecol Oncol , vol.93 , pp. 435-440
    • Yang, H.J.1    Liu, V.W.2    Wang, Y.3
  • 222
    • 33645461015 scopus 로고    scopus 로고
    • Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis
    • Sova P, Feng Q, Geiss G, et al. Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis. Cancer Epidemiol Biomarkers Prev 2006; 15: 114-23.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 114-123
    • Sova, P.1    Feng, Q.2    Geiss, G.3
  • 223
    • 0037348555 scopus 로고    scopus 로고
    • Prevalence of specific types of human papillomavirus and cervical squamous intraepithelial lesions in consecutive, previously unscreened, West-African women over 35 years of age
    • Xi LF, Toure P, Critchlow CW, et al. Prevalence of specific types of human papillomavirus and cervical squamous intraepithelial lesions in consecutive, previously unscreened, West-African women over 35 years of age. Int J Cancer 2003; 103: 803-9.
    • (2003) Int J Cancer , vol.103 , pp. 803-809
    • Xi, L.F.1    Toure, P.2    Critchlow, C.W.3
  • 224
    • 4143072588 scopus 로고    scopus 로고
    • DNA methylation profiling of cervical squamous intraepithelial lesions using liquid-based cytology specimens: An approach that utilizes receiver-operating characteristic analysis
    • Gustafson KS, Furth EE, Heitjan DF, et al. DNA methylation profiling of cervical squamous intraepithelial lesions using liquid-based cytology specimens: an approach that utilizes receiver-operating characteristic analysis. Cancer 2004; 102: 259-68.
    • (2004) Cancer , vol.102 , pp. 259-268
    • Gustafson, K.S.1    Furth, E.E.2    Heitjan, D.F.3
  • 225
    • 20044383919 scopus 로고    scopus 로고
    • Detection of hypermethylated genes in women with and without cervical neoplasia
    • Feng Q, Balasubramanian A, Hawes SE, et al. Detection of hypermethylated genes in women with and without cervical neoplasia. J Natl Cancer Ins 2005; 97: 273-82.
    • (2005) J Natl Cancer Ins , vol.97 , pp. 273-282
    • Feng, Q.1    Balasubramanian, A.2    Hawes, S.E.3
  • 226
    • 0031749535 scopus 로고    scopus 로고
    • Telomerase activity as a biomarker for (pre)neoplastic cervical disease in scrapings and frozen sections from patients with abnormal cervical smear
    • Wisman GB, Hollema H, de Jong S, et al. Telomerase activity as a biomarker for (pre)neoplastic cervical disease in scrapings and frozen sections from patients with abnormal cervical smear. J Clin Oncol 1998; 16: 2238-45.
    • (1998) J Clin Oncol , vol.16 , pp. 2238-2245
    • Wisman, G.B.1    Hollema, H.2    de Jong, S.3
  • 227
    • 1242277423 scopus 로고    scopus 로고
    • Methylation status and expression of E-cadherin and cadherin-11 in gestational trophoblastic diseases
    • Xue WC, Feng HC, Tsao SW, et al. Methylation status and expression of E-cadherin and cadherin-11 in gestational trophoblastic diseases. Int J Gynecol Cancer 2003; 13: 879-88.
    • (2003) Int J Gynecol Cancer , vol.13 , pp. 879-888
    • Xue, W.C.1    Feng, H.C.2    Tsao, S.W.3
  • 228
    • 3543087401 scopus 로고    scopus 로고
    • Down-regulation and promoter methylation of tissue inhibitor of metalloproteinase 3 in choriocarcinoma
    • Feng H, Cheung AN, Xue WC, et al. Down-regulation and promoter methylation of tissue inhibitor of metalloproteinase 3 in choriocarcinoma. Gynecol Oncol 2004; 94: 375-82.
    • (2004) Gynecol Oncol , vol.94 , pp. 375-382
    • Feng, H.1    Cheung, A.N.2    Xue, W.C.3
  • 229
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266: 2011-5.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 230
    • 0029096515 scopus 로고
    • The RNA component of human telomerase
    • Feng J, Funk WD, Wang SS, et al. The RNA component of human telomerase. Science 1995; 269: 1236-41.
    • (1995) Science , vol.269 , pp. 1236-1241
    • Feng, J.1    Funk, W.D.2    Wang, S.S.3
  • 231
    • 27944458006 scopus 로고    scopus 로고
    • Telomerase: Is it the future diagnostic and prognostic tool in human cancer?
    • Mabruk MJ, O'Flatharta C. Telomerase: is it the future diagnostic and prognostic tool in human cancer? Expert Rev Mol Diagn 2005; 5: 907-16.
    • (2005) Expert Rev Mol Diagn , vol.5 , pp. 907-916
    • Mabruk, M.J.1    O'Flatharta, C.2
  • 232
    • 0037461917 scopus 로고    scopus 로고
    • Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase
    • Bilsland AE, Anderson CJ, Fletcher-Monaghan AJ, et al. Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase. Oncogene 2003; 22: 370-80.
    • (2003) Oncogene , vol.22 , pp. 370-380
    • Bilsland, A.E.1    Anderson, C.J.2    Fletcher-Monaghan, A.J.3
  • 234
    • 33646477843 scopus 로고    scopus 로고
    • Telomerase targeting by retinoids in cells from patients with myeloid leukemias of various subtypes, not only APL
    • Pendino F, Hillion J, Dudognon C, et al. Telomerase targeting by retinoids in cells from patients with myeloid leukemias of various subtypes, not only APL. Leukemia 2006; 20: 599-603.
    • (2006) Leukemia , vol.20 , pp. 599-603
    • Pendino, F.1    Hillion, J.2    Dudognon, C.3
  • 235
    • 0141682212 scopus 로고    scopus 로고
    • The evolving role of telomerase inhibitors in the treatment of cancer
    • Mokbel K. The evolving role of telomerase inhibitors in the treatment of cancer. Curr Med Res Opin 2003; 19: 470-2.
    • (2003) Curr Med Res Opin , vol.19 , pp. 470-472
    • Mokbel, K.1
  • 236
    • 16544383400 scopus 로고    scopus 로고
    • Telomerase is frequently activated in tumors with microsatellite instability
    • Ibanez de Caceres I, Frolova N, Varkonyi RJ, et al. Telomerase is frequently activated in tumors with microsatellite instability. Cancer Biol Ther 2004; 3: 289-92.
    • (2004) Cancer Biol Ther , vol.3 , pp. 289-292
    • Ibanez de Caceres, I.1    Frolova, N.2    Varkonyi, R.J.3
  • 237
    • 0035000951 scopus 로고    scopus 로고
    • Telomerase activation by human papillomavirus type 16 E6 protein: Induction of human telomerase reverse transcriptase expression through Myc and GC-rich Sp1 binding sites
    • Oh ST, Kyo S, Laimins LA. Telomerase activation by human papillomavirus type 16 E6 protein: induction of human telomerase reverse transcriptase expression through Myc and GC-rich Sp1 binding sites. J Virol 2001; 75: 5559-66.
    • (2001) J Virol , vol.75 , pp. 5559-5566
    • Oh, S.T.1    Kyo, S.2    Laimins, L.A.3
  • 238
    • 3242679040 scopus 로고    scopus 로고
    • The role of HPV oncoproteins and cellular factors in maintenance of hTERT expression in cervical carcinoma cells
    • Jeong Seo E, Jung Kim H, Jae Lee C, et al. The role of HPV oncoproteins and cellular factors in maintenance of hTERT expression in cervical carcinoma cells. Gynecol Oncol 2004; 94: 40-7.
    • (2004) Gynecol Oncol , vol.94 , pp. 40-47
    • Jeong Seo, E.1    Jung Kim, H.2    Jae Lee, C.3
  • 239
    • 0030747661 scopus 로고    scopus 로고
    • Telomerase activation in cervical cancer
    • Anderson S, Shera K, Ihle J, et al. Telomerase activation in cervical cancer. Am J Pathol 1997; 151: 25-31.
    • (1997) Am J Pathol , vol.151 , pp. 25-31
    • Anderson, S.1    Shera, K.2    Ihle, J.3
  • 240
    • 0030915159 scopus 로고    scopus 로고
    • Differential expression of telomerase activity in human cervical cancer and cervical intraepithelial neoplasia lesions
    • Pao CC, Tseng CJ, Lin CY, et al. Differential expression of telomerase activity in human cervical cancer and cervical intraepithelial neoplasia lesions. J Clin Oncol 1997; 15: 1932-7.
    • (1997) J Clin Oncol , vol.15 , pp. 1932-1937
    • Pao, C.C.1    Tseng, C.J.2    Lin, C.Y.3
  • 241
    • 0032006620 scopus 로고    scopus 로고
    • Telomerase activation in cervical neoplasia
    • Iwasaka T, Zheng PS, Yokoyama M, et al. Telomerase activation in cervical neoplasia. Obstet Gynecol 1998; 91: 260-2.
    • (1998) Obstet Gynecol , vol.91 , pp. 260-262
    • Iwasaka, T.1    Zheng, P.S.2    Yokoyama, M.3
  • 242
    • 0032549082 scopus 로고    scopus 로고
    • Telomerase activity in cervical cancer is quantitatively distinct from that in its precursor lesions
    • Kyo S, Takakura M, Tanaka M, Kanaya T, Inoue M. Telomerase activity in cervical cancer is quantitatively distinct from that in its precursor lesions. Int J Cancer 1998; 79: 66-70.
    • (1998) Int J Cancer , vol.79 , pp. 66-70
    • Kyo, S.1    Takakura, M.2    Tanaka, M.3    Kanaya, T.4    Inoue, M.5
  • 243
    • 0031703757 scopus 로고    scopus 로고
    • Telomerase activity and expression of telomerase RNA component and telomerase catalytic subunit gene in cervical cancer
    • Nakano K, Watney E, McDougall JK. Telomerase activity and expression of telomerase RNA component and telomerase catalytic subunit gene in cervical cancer. Am J Pathol 1998; 153: 857-64.
    • (1998) Am J Pathol , vol.153 , pp. 857-864
    • Nakano, K.1    Watney, E.2    McDougall, J.K.3
  • 244
    • 0031932663 scopus 로고    scopus 로고
    • Telomerase expression in normal epithelium, reactive atypia, squamous dysplasia, and squamous cell carcinoma of the uterine cervix
    • Shroyer KR, Thompson LC, Enomoto T, Eskens JL, Shroyer AL, McGregor JA. Telomerase expression in normal epithelium, reactive atypia, squamous dysplasia, and squamous cell carcinoma of the uterine cervix. Am J Clin Pathol 1998; 109: 153-62.
    • (1998) Am J Clin Pathol , vol.109 , pp. 153-162
    • Shroyer, K.R.1    Thompson, L.C.2    Enomoto, T.3    Eskens, J.L.4    Shroyer, A.L.5    McGregor, J.A.6
  • 245
    • 0032170044 scopus 로고    scopus 로고
    • Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: Strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA
    • Snijders PJ, van Duin M, Walboomers JM, et al. Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA. Cancer Res 1998; 58: 3812-8.
    • (1998) Cancer Res , vol.58 , pp. 3812-3818
    • Snijders, P.J.1    van Duin, M.2    Walboomers, J.M.3
  • 246
    • 0032054313 scopus 로고    scopus 로고
    • Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer
    • Takakura M, Kyo S, Kanaya T, Tanaka M, Inoue M. Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer. Cancer Res 1998; 58: 1558-61.
    • (1998) Cancer Res , vol.58 , pp. 1558-1561
    • Takakura, M.1    Kyo, S.2    Kanaya, T.3    Tanaka, M.4    Inoue, M.5
  • 247
    • 0032055145 scopus 로고    scopus 로고
    • Telomerase activity and expression of its RNA component in cervical lesions
    • Yashima K, Ashfaq R, Nowak J, et al. Telomerase activity and expression of its RNA component in cervical lesions. Cancer 1998; 82: 1319-27.
    • (1998) Cancer , vol.82 , pp. 1319-1327
    • Yashima, K.1    Ashfaq, R.2    Nowak, J.3
  • 248
    • 0032994054 scopus 로고    scopus 로고
    • Clinical significance of telomerase activation and telomeric restriction fragment (TRF) in cervical cancer
    • Zhang DK, Ngan HY, Cheng RY, Cheung AN, Liu SS, Tsao SW. Clinical significance of telomerase activation and telomeric restriction fragment (TRF) in cervical cancer. Eur J Cancer 1999; 35: 154-60.
    • (1999) Eur J Cancer , vol.35 , pp. 154-160
    • Zhang, D.K.1    Ngan, H.Y.2    Cheng, R.Y.3    Cheung, A.N.4    Liu, S.S.5    Tsao, S.W.6
  • 249
    • 0032192188 scopus 로고    scopus 로고
    • Effect of acetic acid on telomerase activity in cervical intraepithelial neoplasia
    • ChangChien CC, Lin H, Leung SW, Hsu CY, Cho CL. Effect of acetic acid on telomerase activity in cervical intraepithelial neoplasia. Gynecol Oncol 1998; 71: 99-103.
    • (1998) Gynecol Oncol , vol.71 , pp. 99-103
    • ChangChien, C.C.1    Lin, H.2    Leung, S.W.3    Hsu, C.Y.4    Cho, C.L.5
  • 250
    • 0035085614 scopus 로고    scopus 로고
    • Relationship between telomerase activation and HPV 16/18 oncogene expression in squamous intraepithelial lesions and squamous cell carcinomas of the uterine cervix
    • Riethdorf S, Riethdorf L, Schulz G, et al. Relationship between telomerase activation and HPV 16/18 oncogene expression in squamous intraepithelial lesions and squamous cell carcinomas of the uterine cervix. Int J Gynecol Pathol 2001; 20: 177-85.
    • (2001) Int J Gynecol Pathol , vol.20 , pp. 177-185
    • Riethdorf, S.1    Riethdorf, L.2    Schulz, G.3
  • 251
    • 0037148289 scopus 로고    scopus 로고
    • Analysis of telomerase as a diagnostic biomarker of cervical dysplasia and carcinoma
    • Jarboe EA, Liaw KL, Thompson LC, et al. Analysis of telomerase as a diagnostic biomarker of cervical dysplasia and carcinoma. Oncogene 2002; 21: 664-73.
    • (2002) Oncogene , vol.21 , pp. 664-673
    • Jarboe, E.A.1    Liaw, K.L.2    Thompson, L.C.3
  • 252
    • 33750463058 scopus 로고    scopus 로고
    • Telomerase activity as an adjunct to high-risk human papillomavirus types 16 and 18 and cytology screening in cervical cancer
    • Kailash U, Soundararajan CC, Lakshmy R, Arora R, Vivekanandhan S, Das BC. Telomerase activity as an adjunct to high-risk human papillomavirus types 16 and 18 and cytology screening in cervical cancer. Br J Cancer 2006; 95: 1250-7.
    • (2006) Br J Cancer , vol.95 , pp. 1250-1257
    • Kailash, U.1    Soundararajan, C.C.2    Lakshmy, R.3    Arora, R.4    Vivekanandhan, S.5    Das, B.C.6
  • 253
    • 0030958979 scopus 로고    scopus 로고
    • Application of telomerase assay for the screening of cervical lesions
    • Kyo S, Takakura M, Ishikawa H, et al. Application of telomerase assay for the screening of cervical lesions. Cancer Res 1997; 57: 1863-7.
    • (1997) Cancer Res , vol.57 , pp. 1863-1867
    • Kyo, S.1    Takakura, M.2    Ishikawa, H.3
  • 254
    • 0034041446 scopus 로고    scopus 로고
    • Telomerase activity in Papanicolaou smear-negative exfoliated cervical cells and its association with lesions and oncogenic human papillomaviruses
    • Zheng PS, Iwasaka T, Zhang ZM, Pater A, Sugimori H. Telomerase activity in Papanicolaou smear-negative exfoliated cervical cells and its association with lesions and oncogenic human papillomaviruses. Gynecol Oncol 2000; 77: 394-8.
    • (2000) Gynecol Oncol , vol.77 , pp. 394-398
    • Zheng, P.S.1    Iwasaka, T.2    Zhang, Z.M.3    Pater, A.4    Sugimori, H.5
  • 255
    • 0037245542 scopus 로고    scopus 로고
    • Detection of telomerase, its components, and human papillomavirus in cervical scrapings as a tool for triage in women with cervical dysplasia
    • Reesink-Peters N, Helder MN, Wisman GB, et al. Detection of telomerase, its components, and human papillomavirus in cervical scrapings as a tool for triage in women with cervical dysplasia. J Clin Pathol 2003; 56: 31-5.
    • (2003) J Clin Pathol , vol.56 , pp. 31-35
    • Reesink-Peters, N.1    Helder, M.N.2    Wisman, G.B.3
  • 256
    • 24644468229 scopus 로고    scopus 로고
    • Potential of telomerase expression and activity in cervical specimens as a diagnostic tool
    • Bravaccini S, Sanchini MA, Amadori A, et al. Potential of telomerase expression and activity in cervical specimens as a diagnostic tool. J Clin Pathol 2005; 58: 911-4.
    • (2005) J Clin Pathol , vol.58 , pp. 911-914
    • Bravaccini, S.1    Sanchini, M.A.2    Amadori, A.3
  • 257
    • 30744460366 scopus 로고    scopus 로고
    • Quantitative determination of human telomerase reverse transcriptase messenger RNA expression in premalignant cervical lesions and correlation with human papillomavirus load
    • Oikonomou P, Mademtzis I, Messinis I, Tsezou A. Quantitative determination of human telomerase reverse transcriptase messenger RNA expression in premalignant cervical lesions and correlation with human papillomavirus load. Hum Pathol 2006; 37: 135-42.
    • (2006) Hum Pathol , vol.37 , pp. 135-142
    • Oikonomou, P.1    Mademtzis, I.2    Messinis, I.3    Tsezou, A.4
  • 258
    • 20244368966 scopus 로고    scopus 로고
    • Genomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer
    • Heselmeyer-Haddad K, Sommerfeld K, White NM, et al. Genomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer. Am J Pathol 2005; 166: 1229-38.
    • (2005) Am J Pathol , vol.166 , pp. 1229-1238
    • Heselmeyer-Haddad, K.1    Sommerfeld, K.2    White, N.M.3
  • 259
    • 0030787753 scopus 로고    scopus 로고
    • Telomerase activity in benign endometrium and endometrial carcinoma
    • Brien TP, Kallakury BV, Lowry CV, et al. Telomerase activity in benign endometrium and endometrial carcinoma. Cancer Res 1997; 57: 2760-4.
    • (1997) Cancer Res , vol.57 , pp. 2760-2764
    • Brien, T.P.1    Kallakury, B.V.2    Lowry, C.V.3
  • 260
    • 17144471436 scopus 로고    scopus 로고
    • Proliferation-associated regulation of telomerase activity in human endometrium and its potential implication in early cancer diagnosis
    • Saito T, Schneider A, Martel N, et al. Proliferation-associated regulation of telomerase activity in human endometrium and its potential implication in early cancer diagnosis. Biochem Biophys Res Commun 1997; 231: 610-4.
    • (1997) Biochem Biophys Res Commun , vol.231 , pp. 610-614
    • Saito, T.1    Schneider, A.2    Martel, N.3
  • 261
    • 0030923751 scopus 로고    scopus 로고
    • Telomerase expression in normal endometrium, endometrial hyperplasia, and endometrial adenocarcinoma
    • Shroyer KR, Stephens JK, Silverberg SG, et al. Telomerase expression in normal endometrium, endometrial hyperplasia, and endometrial adenocarcinoma. Int J Gynecol Pathol 1997; 16: 225-32.
    • (1997) Int J Gynecol Pathol , vol.16 , pp. 225-232
    • Shroyer, K.R.1    Stephens, J.K.2    Silverberg, S.G.3
  • 262
    • 0033524343 scopus 로고    scopus 로고
    • Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues
    • Kyo S, Kanaya T, Takakura M, Tanaka M, Inoue M. Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues. Int J Cancer 1999; 80: 60-3.
    • (1999) Int J Cancer , vol.80 , pp. 60-63
    • Kyo, S.1    Kanaya, T.2    Takakura, M.3    Tanaka, M.4    Inoue, M.5
  • 263
    • 0031794989 scopus 로고    scopus 로고
    • Expression of telomerase activity in human endometrium is localized to epithelial glandular cells and regulated in a menstrual phase-dependent manner correlated with cell proliferation
    • Tanaka M, Kyo S, Takakura M, et al. Expression of telomerase activity in human endometrium is localized to epithelial glandular cells and regulated in a menstrual phase-dependent manner correlated with cell proliferation. Am J Pathol 1998; 153: 1985-91.
    • (1998) Am J Pathol , vol.153 , pp. 1985-1991
    • Tanaka, M.1    Kyo, S.2    Takakura, M.3
  • 264
    • 0034547779 scopus 로고    scopus 로고
    • Expression of telomerase reverse transcriptase mRNA and its quantitative analysis in human endometrial cancer
    • Oshita T, Nagai N, Ohama K. Expression of telomerase reverse transcriptase mRNA and its quantitative analysis in human endometrial cancer. Int J Oncol 2000; 17: 1225-30.
    • (2000) Int J Oncol , vol.17 , pp. 1225-1230
    • Oshita, T.1    Nagai, N.2    Ohama, K.3
  • 265
    • 15244363372 scopus 로고    scopus 로고
    • Immunohistochemical detection of human telomerase reverse transcriptase (hTERT), topoisomerase IIalpha expression, and apoptosis in endometrial adenocarcinoma and atypical hyperplasia
    • Brustmann H. Immunohistochemical detection of human telomerase reverse transcriptase (hTERT), topoisomerase IIalpha expression, and apoptosis in endometrial adenocarcinoma and atypical hyperplasia. Int J Gynecol Pathol 2005; 24: 184-92.
    • (2005) Int J Gynecol Pathol , vol.24 , pp. 184-192
    • Brustmann, H.1
  • 266
    • 0036141098 scopus 로고    scopus 로고
    • Quantitative analysis of telomerase hTERT mRNA and telomerase activity in endometrioid adenocarcinoma and in normal endometrium
    • Lehner R, Enomoto T, McGregor JA, et al. Quantitative analysis of telomerase hTERT mRNA and telomerase activity in endometrioid adenocarcinoma and in normal endometrium. Gynecol Oncol 2002; 84: 120-5.
    • (2002) Gynecol Oncol , vol.84 , pp. 120-125
    • Lehner, R.1    Enomoto, T.2    McGregor, J.A.3
  • 267
    • 0032823839 scopus 로고    scopus 로고
    • Analysis of telomerase activity in ovarian cystadenomas, low-malignant-potential tumors, and invasive carcinomas
    • Datar RH, Naritoku WY, Li P, et al. Analysis of telomerase activity in ovarian cystadenomas, low-malignant-potential tumors, and invasive carcinomas. Gynecol Oncol 1999; 74: 338-45.
    • (1999) Gynecol Oncol , vol.74 , pp. 338-345
    • Datar, R.H.1    Naritoku, W.Y.2    Li, P.3
  • 268
    • 23844447668 scopus 로고    scopus 로고
    • Immunohistochemical detection of human telomerase reverse transcriptase (hTERT) and c-kit in serous ovarian carcinoma: A clinicopathologic study
    • Brustmann H. Immunohistochemical detection of human telomerase reverse transcriptase (hTERT) and c-kit in serous ovarian carcinoma: a clinicopathologic study. Gynecol Oncol 2005; 98: 396-402.
    • (2005) Gynecol Oncol , vol.98 , pp. 396-402
    • Brustmann, H.1
  • 269
    • 0032481426 scopus 로고    scopus 로고
    • Detection of ovarian cancer cells: Comparison of a telomerase assay and cytologic examination
    • Duggan BD, Wan M, Yu MC, et al. Detection of ovarian cancer cells: comparison of a telomerase assay and cytologic examination. J Natl Cancer Inst 1998; 90: 238-42.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 238-242
    • Duggan, B.D.1    Wan, M.2    Yu, M.C.3
  • 270
    • 11144356835 scopus 로고    scopus 로고
    • Detection of residual subclinical ovarian carcinoma after completion of adjuvant chemotherapy
    • Nouriani M, Bahador A, Berek JS, et al. Detection of residual subclinical ovarian carcinoma after completion of adjuvant chemotherapy. Clin Cancer Res 2004; 10: 2681-6.
    • (2004) Clin Cancer Res , vol.10 , pp. 2681-2686
    • Nouriani, M.1    Bahador, A.2    Berek, J.S.3
  • 271
    • 0037837653 scopus 로고    scopus 로고
    • Human telomerase reverse transcriptase mRNA expression assessed by real-time reverse transcription polymerase chain reaction predicts chemosensitivity in patients with ovarian carcinoma
    • Buttitta F, Pellegrini C, Marchetti A, et al. Human telomerase reverse transcriptase mRNA expression assessed by real-time reverse transcription polymerase chain reaction predicts chemosensitivity in patients with ovarian carcinoma. J Clin Oncol 2003; 21: 1320-5.
    • (2003) J Clin Oncol , vol.21 , pp. 1320-1325
    • Buttitta, F.1    Pellegrini, C.2    Marchetti, A.3
  • 272
    • 3242679756 scopus 로고    scopus 로고
    • Effect of all-trans retinoic acid on telomerase activity in ovarian cancer cells
    • Purev E, Soprano DR, Soprano KJ. Effect of all-trans retinoic acid on telomerase activity in ovarian cancer cells. J Exp Clin Cancer Res 2004; 23: 309-16.
    • (2004) J Exp Clin Cancer Res , vol.23 , pp. 309-316
    • Purev, E.1    Soprano, D.R.2    Soprano, K.J.3
  • 273
    • 0032807852 scopus 로고    scopus 로고
    • Telomerase activity in gestational trophoblastic disease
    • Cheung AN, Zhang DK, Liu Y, et al. Telomerase activity in gestational trophoblastic disease. J Clin Pathol 1999; 52: 588-92.
    • (1999) J Clin Pathol , vol.52 , pp. 588-592
    • Cheung, A.N.1    Zhang, D.K.2    Liu, Y.3
  • 274
    • 0032957840 scopus 로고    scopus 로고
    • Telomerase activity in complete hydatidiform mole
    • Bae SN, Kim SJ. Telomerase activity in complete hydatidiform mole. Am J Obstet Gynecol 1999; 180: 328-33.
    • (1999) Am J Obstet Gynecol , vol.180 , pp. 328-333
    • Bae, S.N.1    Kim, S.J.2
  • 275
    • 0019973272 scopus 로고
    • Simultaneous presentation of carcinoma involving the ovary and the uterine corpus
    • Eifel P, Hendrickson M, Ross J, Ballon S, Martinez A, Kempson R. Simultaneous presentation of carcinoma involving the ovary and the uterine corpus. Cancer 1982; 50: 163-70.
    • (1982) Cancer , vol.50 , pp. 163-170
    • Eifel, P.1    Hendrickson, M.2    Ross, J.3    Ballon, S.4    Martinez, A.5    Kempson, R.6
  • 276
    • 0035423062 scopus 로고    scopus 로고
    • Molecular evidence for the independent origin of extra-ovarian papillary serous tumors of low malignant potential
    • Gu J, Roth LM, Younger C, et al. Molecular evidence for the independent origin of extra-ovarian papillary serous tumors of low malignant potential. J Natl Cancer Inst 2001; 93: 1147-52.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1147-1152
    • Gu, J.1    Roth, L.M.2    Younger, C.3
  • 279
    • 0027988421 scopus 로고
    • Analysis of clonality by amplification of short tandem repeats. Carcinomas of the female reproductive tract
    • Enomoto T, Fujita M, Inoue M, et al. Analysis of clonality by amplification of short tandem repeats. Carcinomas of the female reproductive tract. Diagn Mol Pathol 1994; 3: 292-7.
    • (1994) Diagn Mol Pathol , vol.3 , pp. 292-297
    • Enomoto, T.1    Fujita, M.2    Inoue, M.3
  • 280
    • 0028018115 scopus 로고
    • Clonal analysis of human gynecologic cancers by means of the polymerase chain reaction
    • Sawada M, Azuma C, Hashimoto K, et al. Clonal analysis of human gynecologic cancers by means of the polymerase chain reaction. Int J Cancer 1994; 58: 492-6.
    • (1994) Int J Cancer , vol.58 , pp. 492-496
    • Sawada, M.1    Azuma, C.2    Hashimoto, K.3
  • 281
    • 0036282618 scopus 로고    scopus 로고
    • Clonality analysis in synchronous tumors of the female genital tract
    • Prat J. Clonality analysis in synchronous tumors of the female genital tract. Hum Pathol 2002; 33: 383-5.
    • (2002) Hum Pathol , vol.33 , pp. 383-385
    • Prat, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.