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Volumn 21, Issue 2, 2000, Pages 147-151

Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN;

EID: 0033970096     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/21.2.147     Document Type: Article
Times cited : (108)

References (43)
  • 1
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird, A.P. (1986) CpG-rich islands and the function of DNA methylation. Nature, 321, 209-213.
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 2
    • 0023216891 scopus 로고
    • CpG islands in vertebrate genomes
    • Gardiner-Garden, M. and Frommer, M. (1987) CpG islands in vertebrate genomes. J. Mol. Biol., 196, 261-82.
    • (1987) J. Mol. Biol. , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 3
    • 0019510628 scopus 로고
    • Reactivation of an inactive human X chromosome: Evidence for X inactivation by DNA methylation
    • Mohandas, T., Sparkes, R.S. and Shapiro, L.J. (1981) Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation. Science, 211, 393-396.
    • (1981) Science , vol.211 , pp. 393-396
    • Mohandas, T.1    Sparkes, R.S.2    Shapiro, L.J.3
  • 4
    • 0023858127 scopus 로고
    • DNA methylation and genetic inactivation at the thymidine kinase locus: Two different mechanisms for silencing autosomal genes
    • Dobrovic, A., Gareau, J.L., Ouellette, G. and Bradley, W.E.C. (1988) DNA methylation and genetic inactivation at the thymidine kinase locus: two different mechanisms for silencing autosomal genes. Somat. Cell Mol. Genet., 14, 55-68.
    • (1988) Somat. Cell Mol. Genet. , vol.14 , pp. 55-68
    • Dobrovic, A.1    Gareau, J.L.2    Ouellette, G.3    Bradley, W.E.C.4
  • 6
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg, A.P. and Vogelstein, B. (1983) Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature, 301, 89-92.
    • (1983) Nature , vol.301 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 7
    • 0029898837 scopus 로고    scopus 로고
    • DNA methylation errors and cancer
    • Jones, P.A. (1996) DNA methylation errors and cancer. Cancer Res., 56, 2463-2467.
    • (1996) Cancer Res. , vol.56 , pp. 2463-2467
    • Jones, P.A.1
  • 8
    • 0030459140 scopus 로고    scopus 로고
    • The role of DNA methylation in cancer genetics and epigenetics
    • Laird, P.W. and Jaenisch, R. (1996) The role of DNA methylation in cancer genetics and epigenetics. Annu. Rev. Genet., 30, 441-464.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 441-464
    • Laird, P.W.1    Jaenisch, R.2
  • 10
    • 0024365892 scopus 로고
    • Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
    • Greger, V., Passarge, E., Höpping, W., Messmer, E. and Horsthemke, B. (1989) Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet., 83, 155-158.
    • (1989) Hum. Genet. , vol.83 , pp. 155-158
    • Greger, V.1    Passarge, E.2    Höpping, W.3    Messmer, E.4    Horsthemke, B.5
  • 12
    • 0027962591 scopus 로고
    • Frequency and parental origin of hypermethylated RBI alleles in retinoblastoma
    • Greger, V., Debus, N., Lohmann, D., Höpping, W., Passarge, E. and Horsthemke, B. (1994) Frequency and parental origin of hypermethylated RBI alleles in retinoblastoma. Hum. Genet., 94, 491-496.
    • (1994) Hum. Genet. , vol.94 , pp. 491-496
    • Greger, V.1    Debus, N.2    Lohmann, D.3    Höpping, W.4    Passarge, E.5    Horsthemke, B.6
  • 14
    • 0027537296 scopus 로고
    • CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene
    • Ohtani-Fujita, N., Fujita, T., Aoike, A., Osifchin, N.E., Robbins, P.D. and Sakai, T. (1993) CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. Oncogene, 8, 1063-1067.
    • (1993) Oncogene , vol.8 , pp. 1063-1067
    • Ohtani-Fujita, N.1    Fujita, T.2    Aoike, A.3    Osifchin, N.E.4    Robbins, P.D.5    Sakai, T.6
  • 17
    • 0030940091 scopus 로고    scopus 로고
    • Frequent hypermethylation of p16 and p15 genes in multiple myeloma
    • Ng, M.H.L., Chung, Y.F., Lo, K.W., Wickham, N.M.R., Lee, J.C.K. and Huang, D.P. (1997) Frequent hypermethylation of p16 and p15 genes in multiple myeloma. Blood, 89, 2500-2506.
    • (1997) Blood , vol.89 , pp. 2500-2506
    • Ng, M.H.L.1    Chung, Y.F.2    Lo, K.W.3    Wickham, N.M.R.4    Lee, J.C.K.5    Huang, D.P.6
  • 18
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTS1 in human cancers
    • Merlo, A., Herman, J.G., Mao, L., Lee, D.J., Gabrielson, E., Burger, P.C., Baylin, S.B. and Sidransky, D. (1995) 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTS1 in human cancers. Nature Med., 1, 686-692.
    • (1995) Nature Med. , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 19
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/ MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman, J.G., Merlo, A., Mao, L., Lapidus, R.G., Issa, J.P., Davidson, N.E., Sidransky, D. and Baylin, S.B. (1995) Inactivation of the CDKN2/p16/ MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res., 15, 4525-4530.
    • (1995) Cancer Res. , vol.15 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 20
    • 0028875205 scopus 로고
    • Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta, M., Bender, C.M., Yang, A.S., Nguyen, T.D., Beart, R.W., Van Tornout, J.M. and Jones, P.A. (1995) Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res., 55, 4531-4535.
    • (1995) Cancer Res. , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Nguyen, T.D.4    Beart, R.W.5    Van Tornout, J.M.6    Jones, P.A.7
  • 22
    • 0026935108 scopus 로고
    • Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome
    • Smith, S.A., Easton, D.F., Evans, D.G. and Ponder, B.A. (1992) Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome. Nature Genet., 2, 128-31.
    • (1992) Nature Genet. , vol.2 , pp. 128-131
    • Smith, S.A.1    Easton, D.F.2    Evans, D.G.3    Ponder, B.A.4
  • 27
    • 0028950999 scopus 로고
    • Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression
    • Thompson, M.E., Jensen, R.A., Obermiller, P.S., Page, D.L. and Holt, J.T. (1995) Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nature Genet., 9, 444-150.
    • (1995) Nature Genet. , vol.9 , pp. 444-1150
    • Thompson, M.E.1    Jensen, R.A.2    Obermiller, P.S.3    Page, D.L.4    Holt, J.T.5
  • 28
    • 0032497635 scopus 로고    scopus 로고
    • Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells
    • Rice, J.C., Massey-Brown, K.S. and Futscher, B.W. (1998) Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells. Oncogene, 17, 1807-1812.
    • (1998) Oncogene , vol.17 , pp. 1807-1812
    • Rice, J.C.1    Massey-Brown, K.S.2    Futscher, B.W.3
  • 29
    • 0032542339 scopus 로고    scopus 로고
    • Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region
    • Magdinier, F., Ribieras, S., Lenoir, G.M., Frappart, L. and Dante, R. (1998) Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region. Oncogene, 17, 3169-3176.
    • (1998) Oncogene , vol.17 , pp. 3169-3176
    • Magdinier, F.1    Ribieras, S.2    Lenoir, G.M.3    Frappart, L.4    Dante, R.5
  • 30
    • 0031874053 scopus 로고    scopus 로고
    • An important role for BRCA1 in breast cancer progression is indicated by its loss in a large proportion of non-familial breast cancers
    • Taylor, J., Lymboura, M., Pace, P.E., A'hern, R.P., Desai, A.J., Shousha, S., Coombes, R.C. and Ali, S. (1998) An important role for BRCA1 in breast cancer progression is indicated by its loss in a large proportion of non-familial breast cancers. Int. J. Cancer, 79, 334-342.
    • (1998) Int. J. Cancer , vol.79 , pp. 334-342
    • Taylor, J.1    Lymboura, M.2    Pace, P.E.3    A'hern, R.P.4    Desai, A.J.5    Shousha, S.6    Coombes, R.C.7    Ali, S.8
  • 33
    • 0030843274 scopus 로고    scopus 로고
    • Methylation of the BRCA1 gene in sporadic breast cancer
    • Dobrovic, A. and Simpfendorfer, D. (1997) Methylation of the BRCA1 gene in sporadic breast cancer. Cancer Res., 57, 3347-3350.
    • (1997) Cancer Res. , vol.57 , pp. 3347-3350
    • Dobrovic, A.1    Simpfendorfer, D.2
  • 34
    • 0032485196 scopus 로고    scopus 로고
    • CpG methylation within the 5′ regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site
    • Mancini, D.N., Rodenhiser, D.I., Ainsworth, P.J., O'Malley, F.P., Singh, S.M., Xing, W. and Archer, T.K. (1998) CpG methylation within the 5′ regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site. Oncogene, 16, 1161-1169.
    • (1998) Oncogene , vol.16 , pp. 1161-1169
    • Mancini, D.N.1    Rodenhiser, D.I.2    Ainsworth, P.J.3    O'Malley, F.P.4    Singh, S.M.5    Xing, W.6    Archer, T.K.7
  • 35
    • 0033580432 scopus 로고    scopus 로고
    • Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: Correlation with disease characteristics
    • Catteau, A., Harris, W.H., Xu, C.F. and Solomon, E. (1999) Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics. Oncogene, 18, 1957-1965.
    • (1999) Oncogene , vol.18 , pp. 1957-1965
    • Catteau, A.1    Harris, W.H.2    Xu, C.F.3    Solomon, E.4
  • 36
    • 0029934489 scopus 로고    scopus 로고
    • The 5′ end of the BRCA1 gene lies within a duplicated region of human chromosome 17q21
    • Brown, M.A., Xu, C.F., Nicolai, H., Griffiths, B., Chambers, J.A., Black, D. and Solomon, E. (1996) The 5′ end of the BRCA1 gene lies within a duplicated region of human chromosome 17q21. Oncogene, 12, 2507-2513.
    • (1996) Oncogene , vol.12 , pp. 2507-2513
    • Brown, M.A.1    Xu, C.F.2    Nicolai, H.3    Griffiths, B.4    Chambers, J.A.5    Black, D.6    Solomon, E.7
  • 37
    • 0030799598 scopus 로고    scopus 로고
    • Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene
    • Xu, C.F., Brown, M.A., Nicolai, H., Chambers, J.A., Griffiths, B.L. and Solomon, E. (1997) Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene. Hum. Mol. Genet., 6, 1057-1062.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1057-1062
    • Xu, C.F.1    Brown, M.A.2    Nicolai, H.3    Chambers, J.A.4    Griffiths, B.L.5    Solomon, E.6
  • 38
    • 0030447834 scopus 로고    scopus 로고
    • The BRCA1 and IA1.3B promoters are parallel elements of a genomic duplication at 17q21
    • Barker, F., Liu, X. and Almeida, E.R.A. (1996) The BRCA1 and IA1.3B promoters are parallel elements of a genomic duplication at 17q21. Genomics, 38, 215-222.
    • (1996) Genomics , vol.38 , pp. 215-222
    • Barker, F.1    Liu, X.2    Almeida, E.R.A.3
  • 40
  • 42
    • 0025006860 scopus 로고
    • High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
    • Antequera, F., Boyes, J. and Bird, A. (1990) High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell, 62, 503-514.
    • (1990) Cell , vol.62 , pp. 503-514
    • Antequera, F.1    Boyes, J.2    Bird, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.