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Volumn 21, Issue 3, 2007, Pages 292-302

DNA breaks are masked by multiple Rap1 binding in yeast: Implications for telomere capping and telomerase regulation

Author keywords

DNA damage checkpoint; DNA double strand break; Telomerase; Telomere capping; Telomere length regulation

Indexed keywords

DNA; MRE11 PROTEIN; PROTEIN; PROTEIN CDC13; RAP1 PROTEIN; TELOMERASE; UNCLASSIFIED DRUG;

EID: 33846970933     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.400907     Document Type: Article
Times cited : (78)

References (55)
  • 1
    • 33646501933 scopus 로고    scopus 로고
    • The maintenance and masking of chromosome termini
    • Bertuch, A.A. and Lundblad, V. 2006. The maintenance and masking of chromosome termini. Curr. Opin. Cell Biol. 18: 247-253.
    • (2006) Curr. Opin. Cell Biol , vol.18 , pp. 247-253
    • Bertuch, A.A.1    Lundblad, V.2
  • 2
    • 4944265507 scopus 로고    scopus 로고
    • Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1
    • Bianchi, A., Negrini, S., and Shore, D. 2004. Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1. Mol. Cell 16: 139-146.
    • (2004) Mol. Cell , vol.16 , pp. 139-146
    • Bianchi, A.1    Negrini, S.2    Shore, D.3
  • 3
    • 0035504409 scopus 로고    scopus 로고
    • Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction
    • Booth, C., Griffith, E., Brady, G., and Lydall, D. 2001. Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction. Nucleic Acids Res. 29: 4414-4422.
    • (2001) Nucleic Acids Res , vol.29 , pp. 4414-4422
    • Booth, C.1    Griffith, E.2    Brady, G.3    Lydall, D.4
  • 4
    • 0037716757 scopus 로고    scopus 로고
    • Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining
    • Chan, S.W. and Blackburn, E.H. 2003. Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining. Mol. Cell 11: 1379-1387.
    • (2003) Mol. Cell , vol.11 , pp. 1379-1387
    • Chan, S.W.1    Blackburn, E.H.2
  • 5
    • 0036276388 scopus 로고    scopus 로고
    • The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
    • D'Amours, D. and Jackson, S.P. 2002. The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling. Nat. Rev. Mol. Cell Biol. 3: 317-327.
    • (2002) Nat. Rev. Mol. Cell Biol , vol.3 , pp. 317-327
    • D'Amours, D.1    Jackson, S.P.2
  • 6
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • de Lange, T. 2005. Shelterin: The protein complex that shapes and safeguards human telomeres. Genes & Dev. 19: 2100-2110.
    • (2005) Genes & Dev , vol.19 , pp. 2100-2110
    • de Lange, T.1
  • 7
    • 0033598944 scopus 로고    scopus 로고
    • Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases α and δ
    • Diede, S.J. and Gottschling, D.E. 1999. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases α and δ. Cell 99: 723-733.
    • (1999) Cell , vol.99 , pp. 723-733
    • Diede, S.J.1    Gottschling, D.E.2
  • 8
    • 0035806955 scopus 로고    scopus 로고
    • Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere
    • Diede, S.J. and Gottschling, D.E. 2001. Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere. Curr. Biol. 11: 1336-1340.
    • (2001) Curr. Biol , vol.11 , pp. 1336-1340
    • Diede, S.J.1    Gottschling, D.E.2
  • 9
    • 0036021349 scopus 로고    scopus 로고
    • A quantitative assay for telomere protection in Saccharomyces cerevisiae
    • DuBois, M.L., Haimberger, Z.W., McIntosh, M.W., and Gottschling, D.E. 2002. A quantitative assay for telomere protection in Saccharomyces cerevisiae. Genetics 161: 995-1013.
    • (2002) Genetics , vol.161 , pp. 995-1013
    • DuBois, M.L.1    Haimberger, Z.W.2    McIntosh, M.W.3    Gottschling, D.E.4
  • 10
    • 0036677405 scopus 로고    scopus 로고
    • MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae
    • Enomoto, S., Glowczewski, L., and Berman, J. 2002. MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae. Mol. Biol. Cell 13: 2626-2638.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2626-2638
    • Enomoto, S.1    Glowczewski, L.2    Berman, J.3
  • 11
    • 0033214013 scopus 로고    scopus 로고
    • Est1 and Cdc13 as comediators of telomerase access
    • Evans, S.K. and Lundblad, V. 1999. Est1 and Cdc13 as comediators of telomerase access. Science 286: 117-120.
    • (1999) Science , vol.286 , pp. 117-120
    • Evans, S.K.1    Lundblad, V.2
  • 12
    • 27544471936 scopus 로고    scopus 로고
    • Ku: A multifunctional protein involved in telomere maintenance
    • Fisher, T.S. and Zakian, V.A. 2005. Ku: A multifunctional protein involved in telomere maintenance. DNA Repair (Amst.) 4: 1215-1226.
    • (2005) DNA Repair (Amst.) , vol.4 , pp. 1215-1226
    • Fisher, T.S.1    Zakian, V.A.2
  • 13
    • 16544390953 scopus 로고    scopus 로고
    • Cell cycle-dependent regulation of yeast telomerase by Ku
    • Fisher, T.S., Taggart, A.K., and Zakian, V.A. 2004. Cell cycle-dependent regulation of yeast telomerase by Ku. Nat. Struct. Mol. Biol. 11: 1198-1205.
    • (2004) Nat. Struct. Mol. Biol , vol.11 , pp. 1198-1205
    • Fisher, T.S.1    Taggart, A.K.2    Zakian, V.A.3
  • 14
    • 0036864626 scopus 로고    scopus 로고
    • Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination
    • Frank-Vaillant, M. and Marcand, S. 2002. Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination. Mol. Cell 10: 1189-1199.
    • (2002) Mol. Cell , vol.10 , pp. 1189-1199
    • Frank-Vaillant, M.1    Marcand, S.2
  • 16
    • 0028822203 scopus 로고
    • Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
    • Garvik, B., Carson, M., and Hartwell, L. 1995. Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol. Cell. Biol. 15: 6128-6138.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 6128-6138
    • Garvik, B.1    Carson, M.2    Hartwell, L.3
  • 17
    • 0028631862 scopus 로고
    • RAP1 stimulates single- to double-strand association of yeast telomeric DNA: Implications for telomere-telomere interactions
    • Gilson, E., Muller, T., Sogo, J., Laroche, T., and Gasser, S.M. 1994. RAP1 stimulates single- to double-strand association of yeast telomeric DNA: Implications for telomere-telomere interactions. Nucleic Acids Res. 22: 5310-5320.
    • (1994) Nucleic Acids Res , vol.22 , pp. 5310-5320
    • Gilson, E.1    Muller, T.2    Sogo, J.3    Laroche, T.4    Gasser, S.M.5
  • 18
    • 0031029001 scopus 로고    scopus 로고
    • Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13
    • Grandin, N., Reed, S.I., and Charbonneau, M. 1997. Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. Genes & Dev. 11: 512-527.
    • (1997) Genes & Dev , vol.11 , pp. 512-527
    • Grandin, N.1    Reed, S.I.2    Charbonneau, M.3
  • 19
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider, C.W. and Blackburn, E.H. 1985. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43: 405-413.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 21
    • 0035158136 scopus 로고    scopus 로고
    • Telomere formation by rap1p binding site arrays reveals end-specific length regulation requirements and active telomeric recombination
    • Grossi, S., Bianchi, A., Damay, P., and Shore, D. 2001. Telomere formation by rap1p binding site arrays reveals end-specific length regulation requirements and active telomeric recombination. Mol. Cell. Biol. 21: 8117-8128.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 8117-8128
    • Grossi, S.1    Bianchi, A.2    Damay, P.3    Shore, D.4
  • 22
    • 0029994841 scopus 로고    scopus 로고
    • A new efficient gene disruption cassette for repeated use in budding yeast
    • Guldener, U., Heck, S., Fielder, T., Beinhauer, J., and Hegemann, J.H. 1996. A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res. 24: 2519-2524.
    • (1996) Nucleic Acids Res , vol.24 , pp. 2519-2524
    • Guldener, U.1    Heck, S.2    Fielder, T.3    Beinhauer, J.4    Hegemann, J.H.5
  • 23
    • 0035839132 scopus 로고    scopus 로고
    • Telomere dysfunction increases mutation rate and genomic instability
    • Hackett, J.A., Feldser, D.M., and Greider, C.W. 2001. Telomere dysfunction increases mutation rate and genomic instability. Cell 106: 275-286.
    • (2001) Cell , vol.106 , pp. 275-286
    • Hackett, J.A.1    Feldser, D.M.2    Greider, C.W.3
  • 24
    • 0026623241 scopus 로고
    • A RAP1-interacting protein involved in silencing and telomere length regulation
    • Hardy, C.F.J., Sussel, L., and Shore, D. 1992. A RAP1-interacting protein involved in silencing and telomere length regulation. Genes & Dev. 6: 801-814.
    • (1992) Genes & Dev , vol.6 , pp. 801-814
    • Hardy, C.F.J.1    Sussel, L.2    Shore, D.3
  • 26
    • 0036606186 scopus 로고    scopus 로고
    • Saccharomyces Rrm3p, a 5′ to 3′ DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA
    • Ivessa, A.S., Zhou, J.Q., Schulz, V.P., Monson, E.K., and Zakian, V.A. 2002. Saccharomyces Rrm3p, a 5′ to 3′ DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA. Genes & Dev. 16: 1383-1396.
    • (2002) Genes & Dev , vol.16 , pp. 1383-1396
    • Ivessa, A.S.1    Zhou, J.Q.2    Schulz, V.P.3    Monson, E.K.4    Zakian, V.A.5
  • 27
    • 2942644725 scopus 로고    scopus 로고
    • The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex
    • Larrivee, M., LeBel, C., and Wellinger, R.J. 2004. The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex. Genes & Dev. 18: 1391-1396.
    • (2004) Genes & Dev , vol.18 , pp. 1391-1396
    • Larrivee, M.1    LeBel, C.2    Wellinger, R.J.3
  • 28
    • 0032493889 scopus 로고    scopus 로고
    • Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
    • Lee, S.E., Moore, J.K., Holmes, A., Umezu, K., Kolodner, R.D., and Haber, J.E. 1998. Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell 94: 399-409.
    • (1998) Cell , vol.94 , pp. 399-409
    • Lee, S.E.1    Moore, J.K.2    Holmes, A.3    Umezu, K.4    Kolodner, R.D.5    Haber, J.E.6
  • 29
    • 0029128798 scopus 로고
    • Telomerase and DNA: No longer a lagging strand problem?
    • Lingner, J., Cooper, J.P., and Cech, T.R. 1995. Telomerase and DNA: No longer a lagging strand problem? Science 269: 1533-1534.
    • (1995) Science , vol.269 , pp. 1533-1534
    • Lingner, J.1    Cooper, J.P.2    Cech, T.R.3
  • 30
    • 4544281398 scopus 로고    scopus 로고
    • Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins
    • Lisby, M., Barlow, J.H., Burgess, R.C., and Rothstein, R. 2004. Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins. Cell 118: 699-713.
    • (2004) Cell , vol.118 , pp. 699-713
    • Lisby, M.1    Barlow, J.H.2    Burgess, R.C.3    Rothstein, R.4
  • 31
    • 0031820288 scopus 로고    scopus 로고
    • Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
    • Longtine, M.S., McKenzie III, A., Demarini, D.J., Shah, N.G., Wach, A., Brachat, A., Philippsen, P., and Pringle, J.R. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14: 953-961.
    • (1998) Yeast , vol.14 , pp. 953-961
    • Longtine, M.S.1    McKenzie III, A.2    Demarini, D.J.3    Shah, N.G.4    Wach, A.5    Brachat, A.6    Philippsen, P.7    Pringle, J.R.8
  • 32
    • 1942518292 scopus 로고    scopus 로고
    • Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions
    • Makovets, S., Herskowitz, I., and Blackburn, E.H. 2004. Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions. Mol. Cell. Biol. 24: 4019-4031.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 4019-4031
    • Makovets, S.1    Herskowitz, I.2    Blackburn, E.H.3
  • 33
    • 0031036351 scopus 로고    scopus 로고
    • A protein-counting mechanism for telomere length regulation in yeast
    • Marcand, S., Gilson, E., and Shore, D. 1997. A protein-counting mechanism for telomere length regulation in yeast. Science 275: 986-990.
    • (1997) Science , vol.275 , pp. 986-990
    • Marcand, S.1    Gilson, E.2    Shore, D.3
  • 34
    • 0034175814 scopus 로고    scopus 로고
    • Cell cycle restriction of telomere elongation
    • Marcand, S., Brevet, V., Mann, C., and Gilson, E. 2000. Cell cycle restriction of telomere elongation. Curr. Biol. 10: 487-490.
    • (2000) Curr. Biol , vol.10 , pp. 487-490
    • Marcand, S.1    Brevet, V.2    Mann, C.3    Gilson, E.4
  • 35
    • 33745474120 scopus 로고    scopus 로고
    • Break-induced replication and recombinational telomere elongation in yeast
    • McEachern, M.J. and Haber, J.E. 2006. Break-induced replication and recombinational telomere elongation in yeast. Annu. Rev. Biochem. 75: 111-135.
    • (2006) Annu. Rev. Biochem , vol.75 , pp. 111-135
    • McEachern, M.J.1    Haber, J.E.2
  • 36
    • 27644578165 scopus 로고    scopus 로고
    • A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint
    • Michelson, R.J., Rosenstein, S., and Weinert, T. 2005. A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint. Genes & Dev. 19: 2546-2559.
    • (2005) Genes & Dev , vol.19 , pp. 2546-2559
    • Michelson, R.J.1    Rosenstein, S.2    Weinert, T.3
  • 37
    • 0141814665 scopus 로고    scopus 로고
    • Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae
    • Mieczkowski, P.A., Mieczkowska, J.O., Dominska, M., and Petes, T.D. 2003. Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae. Proc. Natl. Acad. Sci. 100: 10854-10859.
    • (2003) Proc. Natl. Acad. Sci , vol.100 , pp. 10854-10859
    • Mieczkowski, P.A.1    Mieczkowska, J.O.2    Dominska, M.3    Petes, T.D.4
  • 38
    • 33645747064 scopus 로고    scopus 로고
    • Semi-conservative DNA replication through telomeres requires Taz1
    • Miller, K.M., Rog, O., and Cooper, J.P. 2006. Semi-conservative DNA replication through telomeres requires Taz1. Nature 440: 824-828.
    • (2006) Nature , vol.440 , pp. 824-828
    • Miller, K.M.1    Rog, O.2    Cooper, J.P.3
  • 39
    • 0028589212 scopus 로고
    • Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy
    • Muller, T., Gilson, E., Schmidt, R., Giraldo, R., Sogo, J., Gross, H., and Gasser, S.M. 1994. Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy. J. Struct. Biol. 113: 1-12.
    • (1994) J. Struct. Biol , vol.113 , pp. 1-12
    • Muller, T.1    Gilson, E.2    Schmidt, R.3    Giraldo, R.4    Sogo, J.5    Gross, H.6    Gasser, S.M.7
  • 40
    • 0034663809 scopus 로고    scopus 로고
    • The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast
    • Paciotti, V., Clerici, M., Lucchini, G., and Longhese, M.P. 2000. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. Genes & Dev. 14: 2046-2059.
    • (2000) Genes & Dev , vol.14 , pp. 2046-2059
    • Paciotti, V.1    Clerici, M.2    Lucchini, G.3    Longhese, M.P.4
  • 41
    • 27144489538 scopus 로고    scopus 로고
    • Rap1 prevents telomere fusions by nonhomologous end joining
    • Pardo, B. and Marcand, S. 2005. Rap1 prevents telomere fusions by nonhomologous end joining. EMBO J. 24: 3117-3127.
    • (2005) EMBO J , vol.24 , pp. 3117-3127
    • Pardo, B.1    Marcand, S.2
  • 42
    • 0035830494 scopus 로고    scopus 로고
    • Cdc13 delivers separate complexes to the telomere for end protection and replication
    • Pennock, E., Buckley, K., and Lundblad, V. 2001. Cdc13 delivers separate complexes to the telomere for end protection and replication. Cell 104: 387-396.
    • (2001) Cell , vol.104 , pp. 387-396
    • Pennock, E.1    Buckley, K.2    Lundblad, V.3
  • 43
    • 0032913466 scopus 로고    scopus 로고
    • The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction
    • Ray, A. and Runge, K.W. 1999. The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction. Mol. Cell. Biol. 19: 31-45.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 31-45
    • Ray, A.1    Runge, K.W.2
  • 44
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery, and chromosome loss
    • Sandell, L.L. and Zakian, V.A. 1993. Loss of a yeast telomere: Arrest, recovery, and chromosome loss. Cell 75: 729-739.
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.A.2
  • 46
    • 0035313820 scopus 로고    scopus 로고
    • Telomeric chromatin: Replicating and wrapping up chromosome ends
    • Shore, D. 2001. Telomeric chromatin: Replicating and wrapping up chromosome ends. Curr. Opin. Genet. Dev. 11: 189-198.
    • (2001) Curr. Opin. Genet. Dev , vol.11 , pp. 189-198
    • Shore, D.1
  • 47
  • 48
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • Smogorzewska, A. and De Lange, T. 2004. Regulation of telomerase by telomeric proteins. Annu. Rev. Biochem. 73: 177-208.
    • (2004) Annu. Rev. Biochem , vol.73 , pp. 177-208
    • Smogorzewska, A.1    De Lange, T.2
  • 49
    • 0037047643 scopus 로고    scopus 로고
    • Est1p as a cell cycle-regulated activator of telomere-bound telomerase
    • Taggart, A.K., Teng, S.C., and Zakian, V.A. 2002. Est1p as a cell cycle-regulated activator of telomere-bound telomerase. Science 297: 1023-1026.
    • (2002) Science , vol.297 , pp. 1023-1026
    • Taggart, A.K.1    Teng, S.C.2    Zakian, V.A.3
  • 50
    • 13944265075 scopus 로고    scopus 로고
    • Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae
    • Takata, H., Tanaka, Y., and Matsuura, A. 2005. Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae. Mol. Cell 17: 573-583.
    • (2005) Mol. Cell , vol.17 , pp. 573-583
    • Takata, H.1    Tanaka, Y.2    Matsuura, A.3
  • 51
    • 2042534735 scopus 로고    scopus 로고
    • Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states
    • Teixeira, M.T., Arneric, M., Sperisen, P., and Lingner, J. 2004. Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states. Cell 117: 323-335.
    • (2004) Cell , vol.117 , pp. 323-335
    • Teixeira, M.T.1    Arneric, M.2    Sperisen, P.3    Lingner, J.4
  • 52
    • 0031027618 scopus 로고    scopus 로고
    • Control of telomere length by the human telomeric protein TRF1
    • van Steensel, B. and de Lange, T. 1997. Control of telomere length by the human telomeric protein TRF1. Nature 385: 740-743.
    • (1997) Nature , vol.385 , pp. 740-743
    • van Steensel, B.1    de Lange, T.2
  • 53
    • 0027212282 scopus 로고
    • Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint
    • Weinert, T.A. and Hartwell, L.H. 1993. Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint. Genetics 134: 63-80.
    • (1993) Genetics , vol.134 , pp. 63-80
    • Weinert, T.A.1    Hartwell, L.H.2
  • 54
    • 0030995534 scopus 로고    scopus 로고
    • A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae
    • Wotton, D. and Shore, D. 1997. A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae. Genes & Dev. 11: 748-760.
    • (1997) Genes & Dev , vol.11 , pp. 748-760
    • Wotton, D.1    Shore, D.2
  • 55
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou, B.B. and Elledge, S.J. 2000. The DNA damage response: Putting checkpoints in perspective. Nature 408: 433-439.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2


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